Gene Gene information from NCBI Gene database.
Entrez ID 91612
Gene name Churchill domain containing 1
Gene symbol CHURC1
Synonyms (NCBI Gene)
C14orf52My015chch
Chromosome 14
Chromosome location 14q23.3
miRNA miRNA information provided by mirtarbase database.
784
miRTarBase ID miRNA Experiments Reference
MIRT440944 hsa-miR-106b-5p HITS-CLIP 22473208
MIRT138670 hsa-miR-155-5p HITS-CLIP 22473208
MIRT440943 hsa-miR-20a-5p HITS-CLIP 22473208
MIRT440944 hsa-miR-106b-5p HITS-CLIP 22473208
MIRT138670 hsa-miR-155-5p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
5
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0008270 Function Zinc ion binding IEA
GO:0008543 Process Fibroblast growth factor receptor signaling pathway IBA
GO:0045893 Process Positive regulation of DNA-templated transcription IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608577 20099 ENSG00000258289
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WUH1
Protein name Protein Churchill
Protein function Transcriptional activator that mediates FGF signaling during neural development (By similarity). Plays a role in the regulation of cell movement (By similarity). ; [Isoform 4
PDB 2JOX
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06573 Churchill 28 138 Churchill protein Family
Sequence
Sequence length 139
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
LUNG ADENOCARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Autistic Disorder Autism BEFREE 21360829
★☆☆☆☆
Found in Text Mining only
Autistic Disorder Autism Pubtator 21360829 Associate
★☆☆☆☆
Found in Text Mining only
Intellectual Disability Intellectual developmental disorder Pubtator 21360829 Associate
★☆☆☆☆
Found in Text Mining only
Learning Disabilities Learning disorders Pubtator 21360829 Associate
★☆☆☆☆
Found in Text Mining only
Schizophrenia Schizophrenia BEFREE 21360829
★☆☆☆☆
Found in Text Mining only