Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	90580
Gene name	Translocase of inner mitochondrial membrane 29
Gene symbol	TIMM29
Synonyms (NCBI Gene)	C19orf52TIM29
Chromosome	19
Chromosome location	19p13.2

136

Show/Hide all (136)

miRTarBase ID	miRNA	Experiments	Reference
MIRT724330	hsa-miR-590-3p	HITS-CLIP	19536157
MIRT724329	hsa-miR-483-5p	HITS-CLIP	19536157
MIRT724328	hsa-miR-4735-5p	HITS-CLIP	19536157
MIRT724327	hsa-miR-4775	HITS-CLIP	19536157
MIRT531649	hsa-miR-4781-3p	HITS-CLIP	21572407
MIRT531648	hsa-miR-1304-3p	HITS-CLIP	21572407
MIRT531644	hsa-miR-6499-3p	HITS-CLIP	21572407
MIRT531643	hsa-miR-3135b	HITS-CLIP	21572407
MIRT531640	hsa-miR-504-3p	HITS-CLIP	21572407
MIRT531639	hsa-miR-122-5p	HITS-CLIP	21572407
MIRT531638	hsa-miR-3652	HITS-CLIP	21572407
MIRT531637	hsa-miR-4430	HITS-CLIP	21572407
MIRT531636	hsa-miR-143-5p	HITS-CLIP	21572407
MIRT531635	hsa-miR-6501-5p	HITS-CLIP	21572407
MIRT531634	hsa-miR-4423-5p	HITS-CLIP	21572407
MIRT531631	hsa-miR-744-3p	HITS-CLIP	21572407
MIRT531630	hsa-miR-5698	HITS-CLIP	21572407
MIRT695877	hsa-miR-26a-1-3p	HITS-CLIP	23313552
MIRT695876	hsa-miR-26a-2-3p	HITS-CLIP	23313552
MIRT695875	hsa-miR-3664-5p	HITS-CLIP	23313552
MIRT695874	hsa-miR-5586-3p	HITS-CLIP	23313552
MIRT695873	hsa-miR-3065-5p	HITS-CLIP	23313552
MIRT621001	hsa-miR-759	HITS-CLIP	23313552
MIRT620999	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT620998	hsa-miR-6742-3p	HITS-CLIP	23313552
MIRT620995	hsa-miR-6776-5p	HITS-CLIP	23313552
MIRT695872	hsa-miR-3120-5p	HITS-CLIP	23313552
MIRT695871	hsa-miR-4522	HITS-CLIP	23313552
MIRT695870	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT695869	hsa-miR-661	HITS-CLIP	23313552
MIRT620993	hsa-miR-6772-5p	HITS-CLIP	23313552
MIRT620992	hsa-miR-4455	HITS-CLIP	23313552
MIRT620991	hsa-miR-609	HITS-CLIP	23313552
MIRT695868	hsa-miR-7159-5p	HITS-CLIP	23313552
MIRT620989	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT620988	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT695867	hsa-miR-6888-3p	HITS-CLIP	23313552
MIRT695866	hsa-miR-6510-3p	HITS-CLIP	23313552
MIRT679448	hsa-miR-6858-3p	HITS-CLIP	23824327
MIRT679447	hsa-miR-4676-5p	HITS-CLIP	23824327
MIRT679446	hsa-miR-575	HITS-CLIP	23824327
MIRT679445	hsa-miR-2392	HITS-CLIP	23824327
MIRT679444	hsa-miR-3622a-3p	HITS-CLIP	23824327
MIRT679443	hsa-miR-3622b-3p	HITS-CLIP	23824327
MIRT679442	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT679441	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679440	hsa-miR-1193	HITS-CLIP	23824327
MIRT679439	hsa-miR-4662a-5p	HITS-CLIP	23824327
MIRT679438	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT679437	hsa-miR-640	HITS-CLIP	23824327
MIRT679436	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679435	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT677568	hsa-miR-8062	HITS-CLIP	23824327
MIRT677567	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677566	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT677565	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677562	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT677561	hsa-miR-4532	HITS-CLIP	23824327
MIRT677557	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT531648	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT679434	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT677553	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT677552	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677551	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT677550	hsa-miR-4284	HITS-CLIP	23824327
MIRT677549	hsa-miR-1297	HITS-CLIP	23824327
MIRT677548	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT677547	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT677546	hsa-miR-4465	HITS-CLIP	23824327
MIRT677544	hsa-miR-7641	HITS-CLIP	23824327
MIRT677568	hsa-miR-8062	HITS-CLIP	23824327
MIRT677567	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677566	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT677565	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT677564	hsa-miR-622	HITS-CLIP	23824327
MIRT677563	hsa-miR-5693	HITS-CLIP	23824327
MIRT677562	hsa-miR-1247-3p	HITS-CLIP	23824327
MIRT677561	hsa-miR-4532	HITS-CLIP	23824327
MIRT677560	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT677559	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT677558	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT677557	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT531648	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT677556	hsa-miR-4264	HITS-CLIP	23824327
MIRT677555	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677554	hsa-miR-1976	HITS-CLIP	23824327
MIRT677553	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT677552	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT677551	hsa-miR-4695-3p	HITS-CLIP	23824327
MIRT677550	hsa-miR-4284	HITS-CLIP	23824327
MIRT677549	hsa-miR-1297	HITS-CLIP	23824327
MIRT677548	hsa-miR-26a-5p	HITS-CLIP	23824327
MIRT677547	hsa-miR-26b-5p	HITS-CLIP	23824327
MIRT677546	hsa-miR-4465	HITS-CLIP	23824327
MIRT677545	hsa-miR-4279	HITS-CLIP	23824327
MIRT677544	hsa-miR-7641	HITS-CLIP	23824327
MIRT621006	hsa-miR-216b-5p	HITS-CLIP	23824327
MIRT621005	hsa-miR-6728-3p	HITS-CLIP	23824327
MIRT621004	hsa-miR-2276-3p	HITS-CLIP	23824327
MIRT621003	hsa-miR-4327	HITS-CLIP	23824327
MIRT621002	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT621001	hsa-miR-759	HITS-CLIP	23824327
MIRT621000	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT620999	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT620998	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT620997	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT620996	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT620995	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT620994	hsa-miR-4252	HITS-CLIP	23824327
MIRT620993	hsa-miR-6772-5p	HITS-CLIP	23824327
MIRT620992	hsa-miR-4455	HITS-CLIP	23824327
MIRT620991	hsa-miR-609	HITS-CLIP	23824327
MIRT620990	hsa-miR-1227-3p	HITS-CLIP	23824327
MIRT620989	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT620988	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT620987	hsa-miR-7703	HITS-CLIP	23824327
MIRT531649	hsa-miR-4781-3p	PAR-CLIP	22012620
MIRT531648	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT531647	hsa-miR-3160-3p	PAR-CLIP	22012620
MIRT531646	hsa-miR-558	PAR-CLIP	22012620
MIRT531645	hsa-miR-4487	PAR-CLIP	22012620
MIRT531644	hsa-miR-6499-3p	PAR-CLIP	22012620
MIRT531643	hsa-miR-3135b	PAR-CLIP	22012620
MIRT531642	hsa-miR-1289	PAR-CLIP	22012620
MIRT531641	hsa-miR-4294	PAR-CLIP	22012620
MIRT531640	hsa-miR-504-3p	PAR-CLIP	22012620
MIRT531639	hsa-miR-122-5p	PAR-CLIP	22012620
MIRT531638	hsa-miR-3652	PAR-CLIP	22012620
MIRT531637	hsa-miR-4430	PAR-CLIP	22012620
MIRT531636	hsa-miR-143-5p	PAR-CLIP	22012620
MIRT531635	hsa-miR-6501-5p	PAR-CLIP	22012620
MIRT531634	hsa-miR-4423-5p	PAR-CLIP	22012620
MIRT531633	hsa-miR-3198	PAR-CLIP	22012620
MIRT531632	hsa-miR-4309	PAR-CLIP	22012620
MIRT531631	hsa-miR-744-3p	PAR-CLIP	22012620
MIRT531630	hsa-miR-5698	PAR-CLIP	22012620

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	27554484, 27718247, 28514442, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	27554484, 27718247, 32901109
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005758	Component	Mitochondrial intermembrane space	IDA	27554484
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0042721	Component	TIM22 mitochondrial import inner membrane insertion complex	IBA
GO:0042721	Component	TIM22 mitochondrial import inner membrane insertion complex	IDA	27554484, 27718247, 28712724, 28712726
GO:0042721	Component	TIM22 mitochondrial import inner membrane insertion complex	IEA
GO:0042721	Component	TIM22 mitochondrial import inner membrane insertion complex	IPI	32901109
GO:0045039	Process	Protein insertion into mitochondrial inner membrane	IBA
GO:0045039	Process	Protein insertion into mitochondrial inner membrane	IDA	28712724, 28712726, 32901109
GO:0045039	Process	Protein insertion into mitochondrial inner membrane	IMP	27554484
GO:0140318	Function	Protein transporter activity	IMP	27554484

MIM	HGNC	e!Ensembl
617380	25152	ENSG00000142444

Q9BSF4

Protein name

Mitochondrial import inner membrane translocase subunit Tim29 (TIM29)

Protein function

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the

PDB

7CGP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10171	Tim29	22 → 186	Translocase of the Inner Mitochondrial membrane 29	Family

Sequence

MAAAALRRFWSRRRAEAGDAVVAKPGVWARLGSWARALLRDYAEACRDASAEARARPGRA
AVYVGLLGGAAACFTLAPSEGAFEEALLEASGTLLLLAPATRNRESEAFVQRLLWLRGRG
RLRYVNLGLCSLVYEAPFDAQASLYQARCRYLQPRWTDFPGRVLDVGFVGRWWVLGAWMR
DCDINDDEFLHLPAHLRVVGPQQLHSETNERLFDEKYKPVVLTDDQVDQALWEEQVLQKE
KKDRLALSQAHSLVQAEAPR

Sequence length

260

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
MYOCARDIAL INFARCTION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

TIMM29 (translocase of inner mitochondrial membrane 29)