Gene Gene information from NCBI Gene database.
Entrez ID 90273
Gene name CEA cell adhesion molecule 21
Gene symbol CEACAM21
Synonyms (NCBI Gene)
CEACAM3R29124_1
Chromosome 19
Chromosome location 19q13.2
miRNA miRNA information provided by mirtarbase database.
13
miRTarBase ID miRNA Experiments Reference
MIRT017227 hsa-miR-335-5p Microarray 18185580
MIRT882982 hsa-miR-3127-5p CLIP-seq
MIRT882983 hsa-miR-4270 CLIP-seq
MIRT882984 hsa-miR-4441 CLIP-seq
MIRT882985 hsa-miR-4446-3p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
GO ID Ontology Definition Evidence Reference
GO:0006955 Process Immune response IBA
GO:0009897 Component External side of plasma membrane IBA
GO:0016020 Component Membrane IEA
GO:0042110 Process T cell activation IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
618191 28834 ENSG00000007129
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q3KPI0
Protein name Cell adhesion molecule CEACAM21 (Carcinoembryonic antigen-related cell adhesion molecule 21) (CEA cell adhesion molecule 21)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 38 141 Immunoglobulin V-set domain Domain
PF00047 ig 149 226 Immunoglobulin domain Domain
Sequence
Sequence length 293
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
LUNG ADENOCARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA Disgenet, GWAS catalog
Disgenet, GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Cerebrovascular Accidents Stroke BEFREE 31603298
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 31295447, 7808000
★☆☆☆☆
Found in Text Mining only
Acute Promyelocytic Leukemia Promyelocytic Leukemia BEFREE 2789512
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Adenocarcinoma BEFREE 11263866, 1484322, 17540439, 21397974, 24852187, 27072585, 28877268, 29069854, 30115364, 30458812, 30849967, 7690349
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma Of Esophagus Esophageal Cancer BEFREE 30724779
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of lung (disorder) Lung adenocarcinoma BEFREE 23099808, 24487967, 27990560, 28705152, 29069748, 30647803, 30944644
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of pancreas Pancreatic adenocarcinoma BEFREE 30153903
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of rectum Adenocarcinoma Of Rectum BEFREE 30822523
★☆☆☆☆
Found in Text Mining only
Adenoma Adenoma BEFREE 2067130, 27100181
★☆☆☆☆
Found in Text Mining only
Adenoma of large intestine Colorectal adenoma BEFREE 2125040, 3544799
★☆☆☆☆
Found in Text Mining only