VWA5B2 (von Willebrand factor A domain containing 5B2)

Gene

• Entrez ID: 90113
• Gene name: Von Willebrand factor A domain containing 5B2
• Gene symbol: VWA5B2
• Synonyms (NCBI Gene): -
• Chromosome: 3
• Chromosome location: 3q27.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1488334	hsa-miR-3150b-3p	CLIP-seq
MIRT1488335	hsa-miR-342-5p	CLIP-seq
MIRT1488336	hsa-miR-3689a-3p	CLIP-seq
MIRT1488337	hsa-miR-3689c	CLIP-seq
MIRT1488338	hsa-miR-4419a	CLIP-seq
MIRT1488339	hsa-miR-4481	CLIP-seq
MIRT1488340	hsa-miR-4510	CLIP-seq
MIRT1488341	hsa-miR-4651	CLIP-seq
MIRT1488342	hsa-miR-4664-5p	CLIP-seq
MIRT1488343	hsa-miR-4728-5p	CLIP-seq
MIRT1488344	hsa-miR-4745-5p	CLIP-seq
MIRT1488345	hsa-miR-4758-5p	CLIP-seq
MIRT1488346	hsa-miR-4784	CLIP-seq
MIRT1488347	hsa-miR-574-5p	CLIP-seq
MIRT1488348	hsa-miR-608	CLIP-seq
MIRT1488349	hsa-miR-765	CLIP-seq
MIRT2367556	hsa-miR-1321	CLIP-seq
MIRT2367557	hsa-miR-1909	CLIP-seq
MIRT2367558	hsa-miR-2392	CLIP-seq
MIRT2367559	hsa-miR-3162-5p	CLIP-seq
MIRT2367560	hsa-miR-3164	CLIP-seq
MIRT2367561	hsa-miR-3194-5p	CLIP-seq
MIRT2367562	hsa-miR-34a	CLIP-seq
MIRT2367563	hsa-miR-34c-5p	CLIP-seq
MIRT2367564	hsa-miR-3605-5p	CLIP-seq
MIRT2367565	hsa-miR-3653	CLIP-seq
MIRT2367566	hsa-miR-3659	CLIP-seq
MIRT2367567	hsa-miR-3670	CLIP-seq
MIRT2367568	hsa-miR-4257	CLIP-seq
MIRT2367569	hsa-miR-4270	CLIP-seq
MIRT2367570	hsa-miR-4292	CLIP-seq
MIRT2367571	hsa-miR-4300	CLIP-seq
MIRT1488338	hsa-miR-4419a	CLIP-seq
MIRT2367572	hsa-miR-4441	CLIP-seq
MIRT2367573	hsa-miR-4486	CLIP-seq
MIRT2367574	hsa-miR-449a	CLIP-seq
MIRT2367575	hsa-miR-449b	CLIP-seq
MIRT1488340	hsa-miR-4510	CLIP-seq
MIRT2367576	hsa-miR-4658	CLIP-seq
MIRT2367577	hsa-miR-4684-3p	CLIP-seq
MIRT2367578	hsa-miR-4721	CLIP-seq
MIRT1488343	hsa-miR-4728-5p	CLIP-seq
MIRT2367579	hsa-miR-4739	CLIP-seq
MIRT2367580	hsa-miR-4756-5p	CLIP-seq
MIRT1488345	hsa-miR-4758-5p	CLIP-seq
MIRT1488347	hsa-miR-574-5p	CLIP-seq
MIRT2367581	hsa-miR-892a	CLIP-seq
MIRT2367582	hsa-miR-920	CLIP-seq
MIRT2661043	hsa-miR-15a	CLIP-seq
MIRT2661044	hsa-miR-15b	CLIP-seq
MIRT2661045	hsa-miR-16	CLIP-seq
MIRT2367557	hsa-miR-1909	CLIP-seq
MIRT2661046	hsa-miR-195	CLIP-seq
MIRT2661047	hsa-miR-214	CLIP-seq
MIRT2367561	hsa-miR-3194-5p	CLIP-seq
MIRT2661048	hsa-miR-3619-5p	CLIP-seq
MIRT2661049	hsa-miR-424	CLIP-seq
MIRT2661050	hsa-miR-4690-3p	CLIP-seq
MIRT2661051	hsa-miR-486-3p	CLIP-seq
MIRT2661052	hsa-miR-497	CLIP-seq
MIRT2661053	hsa-miR-761	CLIP-seq
MIRT2661043	hsa-miR-15a	CLIP-seq
MIRT2661044	hsa-miR-15b	CLIP-seq
MIRT2661045	hsa-miR-16	CLIP-seq
MIRT2367557	hsa-miR-1909	CLIP-seq
MIRT2661046	hsa-miR-195	CLIP-seq
MIRT2661047	hsa-miR-214	CLIP-seq
MIRT2367561	hsa-miR-3194-5p	CLIP-seq
MIRT2661048	hsa-miR-3619-5p	CLIP-seq
MIRT2661049	hsa-miR-424	CLIP-seq
MIRT2661050	hsa-miR-4690-3p	CLIP-seq
MIRT2661051	hsa-miR-486-3p	CLIP-seq
MIRT2661052	hsa-miR-497	CLIP-seq
MIRT2661053	hsa-miR-761	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N398
• Protein name: von Willebrand factor A domain-containing protein 5B2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13757	VIT_2	2 → 79	Vault protein inter-alpha-trypsin domain	Domain
  PF13768	VWA_3	353 → 501	von Willebrand factor type A domain	Domain

• Sequence:

  MPGLYCPSSWTPLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVS
  GFEAEAAGRRVSFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLP
  TGIIAAAGTMTVTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTS
  CFGVGSLQEEGLAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRA
  DAPPHASSAATICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARR
  DFQRLQRRDSDGDRQVWFLQRRFHKDILLNPVLALSFCPDLSSKPGHLGTATRELLFLLD
  SSSVAHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESIETLQVP
  SGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTARCFSFGL
  GPTCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFVPDTVEAL
  LTPREIPALYPGDQLLGYCSLFRVDGFRSRPPGGQEPGWQSSGGSVFPSPEEAPSAASPG
  TEPTGTSEPLGTGTVSAELSSPWAARDSEQSTDALTDPVTDPGPNPSDTAIWRRIFQSSY
  IREQYVLTHCSASPEPGPGSTGSSESPGSQGPGSPEGSAPLEPPSQQGCRSLAWGEPAGS
  RSCPLPAPTPAPFKVGALSTEVLGRQHRAALAGRSLSSPPGRANQVPGRPRKPSLGAILD
  GPSPEPGQQLGQGLDDSGNLLSPAPMDWDMLMEPPFLFTAVPPSGELAPPAVPPQAPRCH
  VVIRGLCGEQPMCWEVGVGLETLWGPGDGSQPPSPPVREAAWDQALHRLTAASVVRDNEQ
  LALRGGAETTADRGHARRCWLRALQTSKVSSAPSCFTCPVAVDATTREVLPGALQVCSSE
  PAEPPGTPPASHSHLDAAPLPTVVYSKGLQRGSPAGAWDSDQNGNSKRALGDPATPTEGP
  RRPPPRPPCRLSMGRRHKLCSPDPGQANNSEGSDHDYLPLVRLQEAPGSFRLDAPFCAAV
  RISQERLCRASPFAVHRASLSPTSASLPWALLGPGVGQGDSATASCSPSPSSGSEGPGQV
  DSGRGSDTEASEGAEGLGGTDLRGRTWATAVALAWLEHRCAAAFDEWELTAAKADCWLRA
  QHLPDGLDLAALKAAARGLFLLLRHWDQNLQLHLLCYSPANV

• Sequence length: 1242

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE ID	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations