FAM181A (family with sequence similarity 181 member A)

Gene

• Entrez ID: 90050
• Gene name: Family with sequence similarity 181 member A
• Gene symbol: FAM181A
• Synonyms (NCBI Gene): C14orf152
• Chromosome: 14
• Chromosome location: 14q32.12

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT982405	hsa-miR-1233	CLIP-seq
MIRT982406	hsa-miR-1913	CLIP-seq
MIRT982407	hsa-miR-3150b-3p	CLIP-seq
MIRT982408	hsa-miR-3173-5p	CLIP-seq
MIRT982409	hsa-miR-324-3p	CLIP-seq
MIRT982410	hsa-miR-4689	CLIP-seq
MIRT982411	hsa-miR-4784	CLIP-seq
MIRT982412	hsa-miR-544b	CLIP-seq
MIRT982413	hsa-miR-2276	CLIP-seq
MIRT982414	hsa-miR-3179	CLIP-seq
MIRT982415	hsa-miR-3929	CLIP-seq
MIRT982416	hsa-miR-4419b	CLIP-seq
MIRT982417	hsa-miR-4478	CLIP-seq
MIRT982418	hsa-miR-4708-3p	CLIP-seq
MIRT2225328	hsa-miR-2115	CLIP-seq
MIRT982413	hsa-miR-2276	CLIP-seq
MIRT2225329	hsa-miR-3202	CLIP-seq
MIRT982418	hsa-miR-4708-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IDA	28891297

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8N9Y4
• Protein name: Protein FAM181A
• PDB: 6L9F, 6SEN
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15238	FAM181	63 → 342	FAM181	Family

• Sequence:

  MPLEERRSSGERNDAAPTNHRRPGEKRASTAKQVSSVPFLGAAGHQQSLPSSWKASCSGP
  LVMASDSDVKMLLNFVNLASSDIKAALDKSAPCRRSVDHRKYLQKQLKRFSQKYSRLPRG
  LPGRAAEPYLKRGSEDRPRRLLLDLGPDSSPGGGGGCKEKVLRNPYREECLAKEQLPQRQ
  HPEAAQPGQVPMRKRQLPASFWEEPRPTHSYHVGLEGGLGPREGPPYEGKKNCKGLEPLG
  PETTLVSMSPRALAEKEPLKMPGVSLVGRVNAWSCCPFQYHGQPIYPGPLGALPQSPVPS
  LGLWRKSPAFPGELAHLCKDVDGLGQKVCRPVVLKPIPTKPAVPPPIFNVFGYL

• Sequence length: 354

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer`s Disease	Alzheimer disease	GWASCAT_DG	26830138		★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	Pubtator	25288825	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33080570	Associate	★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Thyroid cancer	Pubtator	35642209	Associate	★☆☆☆☆ Found in Text Mining only