LMLN (leishmanolysin like peptidase)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 89782 |
| Gene name | Leishmanolysin like peptidase |
| Gene symbol | LMLN |
| Synonyms (NCBI Gene) |
GP63INVIX14LMNL1MSP
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| Chromosome | 3 |
| Chromosome location | 3q29 |
| Summary | This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96KR4 | ||||||||||||||||||||
| Protein name | Leishmanolysin-like peptidase (EC 3.4.24.-) (Invadolysin) | ||||||||||||||||||||
| Protein function | Metalloprotease. | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in all cell lines analyzed. {ECO:0000269|PubMed:19706689}. | ||||||||||||||||||||
| Sequence |
MVTTLGPKMAAEWGGGVGYSGSGPGRSRWRWSGSVWVRSVLLLLGGLRASATSTPVSLGS |
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| Sequence length | 655 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with LMLN across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to LMLN (see Related Genes above), that are NOT already directly curated for LMLN itself -- a lead worth checking, not a confirmed association.
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