Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	8945
Gene name	Beta-transducin repeat containing E3 ubiquitin protein ligase
Gene symbol	BTRC
Synonyms (NCBI Gene)	BETA-TRCPFBW1AFBXW1FBXW1AFWD1bTrCPbTrCP1betaTrCP
Chromosome	10
Chromosome location	10q24.32
Summary	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), w

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004673	hsa-miR-183-5p	5'RACEqRT-PCRWestern blot	19647520
MIRT005510	hsa-miR-10a-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	20624982
MIRT016603	hsa-miR-193b-3p	Microarray	20304954
MIRT051452	hsa-let-7e-5p	CLASH	23622248
MIRT051351	hsa-miR-15a-5p	CLASH	23622248
MIRT051304	hsa-miR-16-5p	CLASH	23622248
MIRT049068	hsa-miR-92a-3p	CLASH	23622248
MIRT044652	hsa-miR-320a	CLASH	23622248
MIRT437793	hsa-miR-195-5p	Luciferase reporter assayWestern blot	23544130
MIRT437794	hsa-miR-497-5p	Luciferase reporter assayWestern blot	23544130
MIRT480603	hsa-miR-3974	PAR-CLIP	22012620
MIRT512876	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT512875	hsa-miR-624-5p	PAR-CLIP	22012620
MIRT528631	hsa-miR-6871-5p	PAR-CLIP	22012620
MIRT512874	hsa-miR-4709-5p	PAR-CLIP	22012620
MIRT512873	hsa-miR-554	PAR-CLIP	22012620
MIRT528630	hsa-miR-493-3p	PAR-CLIP	22012620
MIRT528629	hsa-miR-505-3p	PAR-CLIP	22012620
MIRT528628	hsa-miR-3115	PAR-CLIP	22012620
MIRT528627	hsa-miR-421	PAR-CLIP	22012620
MIRT528626	hsa-miR-6884-5p	PAR-CLIP	22012620
MIRT512876	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT512875	hsa-miR-624-5p	PAR-CLIP	23446348
MIRT512874	hsa-miR-4709-5p	PAR-CLIP	23446348
MIRT512873	hsa-miR-554	PAR-CLIP	23446348
MIRT480604	hsa-miR-3714	PAR-CLIP	22291592
MIRT496800	hsa-miR-4695-5p	PAR-CLIP	22291592
MIRT496799	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496798	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496797	hsa-miR-940	PAR-CLIP	22291592
MIRT496796	hsa-miR-4762-5p	PAR-CLIP	22291592
MIRT480598	hsa-miR-4459	PAR-CLIP	22291592
MIRT496795	hsa-miR-4514	PAR-CLIP	22291592
MIRT496794	hsa-miR-4692	PAR-CLIP	22291592
MIRT496793	hsa-miR-605-3p	PAR-CLIP	22291592
MIRT496792	hsa-miR-5008-5p	PAR-CLIP	22291592
MIRT496791	hsa-miR-4722-5p	PAR-CLIP	22291592
MIRT496790	hsa-miR-3136-3p	PAR-CLIP	22291592
MIRT496789	hsa-miR-7155-3p	PAR-CLIP	22291592
MIRT480605	hsa-miR-548an	PAR-CLIP	23592263
MIRT480604	hsa-miR-3714	PAR-CLIP	23592263
MIRT480603	hsa-miR-3974	PAR-CLIP	23592263
MIRT480602	hsa-miR-2682-5p	PAR-CLIP	23592263
MIRT480601	hsa-miR-34b-5p	PAR-CLIP	23592263
MIRT480600	hsa-miR-449c-5p	PAR-CLIP	23592263
MIRT480599	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT480598	hsa-miR-4459	PAR-CLIP	23592263
MIRT480597	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT480596	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT480595	hsa-miR-765	PAR-CLIP	23592263
MIRT480594	hsa-miR-548au-3p	PAR-CLIP	23592263
MIRT480593	hsa-miR-4271	PAR-CLIP	23592263
MIRT051351	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT728171	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT051304	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT437793	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT480603	hsa-miR-3974	PAR-CLIP	22012620
MIRT512876	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT512875	hsa-miR-624-5p	PAR-CLIP	22012620
MIRT528631	hsa-miR-6871-5p	PAR-CLIP	22012620
MIRT512874	hsa-miR-4709-5p	PAR-CLIP	22012620
MIRT512873	hsa-miR-554	PAR-CLIP	22012620
MIRT528630	hsa-miR-493-3p	PAR-CLIP	22012620
MIRT528629	hsa-miR-505-3p	PAR-CLIP	22012620
MIRT528628	hsa-miR-3115	PAR-CLIP	22012620
MIRT528627	hsa-miR-421	PAR-CLIP	22012620
MIRT528626	hsa-miR-6884-5p	PAR-CLIP	22012620
MIRT512876	hsa-miR-101-3p	PAR-CLIP	23446348
MIRT512875	hsa-miR-624-5p	PAR-CLIP	23446348
MIRT512874	hsa-miR-4709-5p	PAR-CLIP	23446348
MIRT512873	hsa-miR-554	PAR-CLIP	23446348
MIRT480604	hsa-miR-3714	PAR-CLIP	22291592
MIRT496800	hsa-miR-4695-5p	PAR-CLIP	22291592
MIRT496799	hsa-miR-6808-5p	PAR-CLIP	22291592
MIRT496798	hsa-miR-6893-5p	PAR-CLIP	22291592
MIRT496797	hsa-miR-940	PAR-CLIP	22291592
MIRT496796	hsa-miR-4762-5p	PAR-CLIP	22291592
MIRT480598	hsa-miR-4459	PAR-CLIP	22291592
MIRT496795	hsa-miR-4514	PAR-CLIP	22291592
MIRT496794	hsa-miR-4692	PAR-CLIP	22291592
MIRT496793	hsa-miR-605-3p	PAR-CLIP	22291592
MIRT496792	hsa-miR-5008-5p	PAR-CLIP	22291592
MIRT496791	hsa-miR-4722-5p	PAR-CLIP	22291592
MIRT496790	hsa-miR-3136-3p	PAR-CLIP	22291592
MIRT496789	hsa-miR-7155-3p	PAR-CLIP	22291592
MIRT480605	hsa-miR-548an	PAR-CLIP	23592263
MIRT480604	hsa-miR-3714	PAR-CLIP	23592263
MIRT480603	hsa-miR-3974	PAR-CLIP	23592263
MIRT480602	hsa-miR-2682-5p	PAR-CLIP	23592263
MIRT480601	hsa-miR-34b-5p	PAR-CLIP	23592263
MIRT480600	hsa-miR-449c-5p	PAR-CLIP	23592263
MIRT480599	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT480598	hsa-miR-4459	PAR-CLIP	23592263
MIRT480597	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT480596	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT480595	hsa-miR-765	PAR-CLIP	23592263
MIRT480594	hsa-miR-548au-3p	PAR-CLIP	23592263
MIRT480593	hsa-miR-4271	PAR-CLIP	23592263
MIRT005510	hsa-miR-10a-5p	Luciferase reporter assayWestern blotting	36199080
MIRT827508	hsa-miR-1185	CLIP-seq
MIRT827509	hsa-miR-1225-5p	CLIP-seq
MIRT827510	hsa-miR-1236	CLIP-seq
MIRT827511	hsa-miR-1248	CLIP-seq
MIRT827512	hsa-miR-1253	CLIP-seq
MIRT827513	hsa-miR-1254	CLIP-seq
MIRT827514	hsa-miR-1285	CLIP-seq
MIRT827515	hsa-miR-1343	CLIP-seq
MIRT827516	hsa-miR-145	CLIP-seq
MIRT827517	hsa-miR-15a	CLIP-seq
MIRT827518	hsa-miR-15b	CLIP-seq
MIRT827519	hsa-miR-16	CLIP-seq
MIRT827520	hsa-miR-181a	CLIP-seq
MIRT827521	hsa-miR-181b	CLIP-seq
MIRT827522	hsa-miR-181c	CLIP-seq
MIRT827523	hsa-miR-181d	CLIP-seq
MIRT827524	hsa-miR-185	CLIP-seq
MIRT827525	hsa-miR-195	CLIP-seq
MIRT827526	hsa-miR-198	CLIP-seq
MIRT827527	hsa-miR-214	CLIP-seq
MIRT827528	hsa-miR-218	CLIP-seq
MIRT827529	hsa-miR-223	CLIP-seq
MIRT827530	hsa-miR-2355-5p	CLIP-seq
MIRT827531	hsa-miR-3116	CLIP-seq
MIRT827532	hsa-miR-3123	CLIP-seq
MIRT827533	hsa-miR-3150b-3p	CLIP-seq
MIRT827534	hsa-miR-3163	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT827536	hsa-miR-3174	CLIP-seq
MIRT827537	hsa-miR-3180-5p	CLIP-seq
MIRT827538	hsa-miR-3182	CLIP-seq
MIRT827539	hsa-miR-3187-5p	CLIP-seq
MIRT827540	hsa-miR-3189-3p	CLIP-seq
MIRT827541	hsa-miR-3202	CLIP-seq
MIRT827542	hsa-miR-330-3p	CLIP-seq
MIRT827543	hsa-miR-3591-5p	CLIP-seq
MIRT827544	hsa-miR-3606	CLIP-seq
MIRT827545	hsa-miR-3615	CLIP-seq
MIRT827546	hsa-miR-3616-3p	CLIP-seq
MIRT827547	hsa-miR-3617	CLIP-seq
MIRT827548	hsa-miR-3619-5p	CLIP-seq
MIRT827549	hsa-miR-3662	CLIP-seq
MIRT827550	hsa-miR-3668	CLIP-seq
MIRT827551	hsa-miR-3679-5p	CLIP-seq
MIRT827552	hsa-miR-3691-3p	CLIP-seq
MIRT827553	hsa-miR-3925-5p	CLIP-seq
MIRT827554	hsa-miR-3927	CLIP-seq
MIRT827555	hsa-miR-3938	CLIP-seq
MIRT827556	hsa-miR-3976	CLIP-seq
MIRT827557	hsa-miR-411	CLIP-seq
MIRT827558	hsa-miR-424	CLIP-seq
MIRT827559	hsa-miR-4262	CLIP-seq
MIRT827560	hsa-miR-4274	CLIP-seq
MIRT827561	hsa-miR-4276	CLIP-seq
MIRT827562	hsa-miR-4286	CLIP-seq
MIRT827563	hsa-miR-4291	CLIP-seq
MIRT827564	hsa-miR-4302	CLIP-seq
MIRT827565	hsa-miR-4306	CLIP-seq
MIRT827566	hsa-miR-4310	CLIP-seq
MIRT827567	hsa-miR-4422	CLIP-seq
MIRT827568	hsa-miR-4461	CLIP-seq
MIRT827569	hsa-miR-448	CLIP-seq
MIRT827570	hsa-miR-4506	CLIP-seq
MIRT827571	hsa-miR-4524	CLIP-seq
MIRT827572	hsa-miR-4640-5p	CLIP-seq
MIRT827573	hsa-miR-4644	CLIP-seq
MIRT827574	hsa-miR-4646-5p	CLIP-seq
MIRT827575	hsa-miR-4650-3p	CLIP-seq
MIRT827576	hsa-miR-4662a-3p	CLIP-seq
MIRT827577	hsa-miR-4663	CLIP-seq
MIRT827578	hsa-miR-4666-5p	CLIP-seq
MIRT827579	hsa-miR-4697-3p	CLIP-seq
MIRT827580	hsa-miR-4712-5p	CLIP-seq
MIRT827581	hsa-miR-4719	CLIP-seq
MIRT827582	hsa-miR-4721	CLIP-seq
MIRT827583	hsa-miR-4724-3p	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827585	hsa-miR-4726-5p	CLIP-seq
MIRT827586	hsa-miR-4747-5p	CLIP-seq
MIRT827587	hsa-miR-4762-3p	CLIP-seq
MIRT827588	hsa-miR-4764-3p	CLIP-seq
MIRT827589	hsa-miR-4766-5p	CLIP-seq
MIRT827590	hsa-miR-4779	CLIP-seq
MIRT827591	hsa-miR-4784	CLIP-seq
MIRT827592	hsa-miR-488	CLIP-seq
MIRT827593	hsa-miR-497	CLIP-seq
MIRT827594	hsa-miR-499a-5p	CLIP-seq
MIRT827595	hsa-miR-503	CLIP-seq
MIRT827596	hsa-miR-513b	CLIP-seq
MIRT827597	hsa-miR-518d-5p	CLIP-seq
MIRT827598	hsa-miR-519b-5p	CLIP-seq
MIRT827599	hsa-miR-519c-5p	CLIP-seq
MIRT827600	hsa-miR-520c-5p	CLIP-seq
MIRT827601	hsa-miR-526a	CLIP-seq
MIRT827602	hsa-miR-542-5p	CLIP-seq
MIRT827603	hsa-miR-543	CLIP-seq
MIRT827604	hsa-miR-548m	CLIP-seq
MIRT827605	hsa-miR-549	CLIP-seq
MIRT827606	hsa-miR-556-3p	CLIP-seq
MIRT827607	hsa-miR-580	CLIP-seq
MIRT827608	hsa-miR-583	CLIP-seq
MIRT827609	hsa-miR-584	CLIP-seq
MIRT827610	hsa-miR-586	CLIP-seq
MIRT827611	hsa-miR-590-3p	CLIP-seq
MIRT827612	hsa-miR-612	CLIP-seq
MIRT827613	hsa-miR-618	CLIP-seq
MIRT827614	hsa-miR-641	CLIP-seq
MIRT827615	hsa-miR-646	CLIP-seq
MIRT827616	hsa-miR-661	CLIP-seq
MIRT827617	hsa-miR-761	CLIP-seq
MIRT827618	hsa-miR-770-5p	CLIP-seq
MIRT827619	hsa-miR-802	CLIP-seq
MIRT827620	hsa-miR-890	CLIP-seq
MIRT827621	hsa-miR-891b	CLIP-seq
MIRT827622	hsa-miR-921	CLIP-seq
MIRT827623	hsa-miR-922	CLIP-seq
MIRT827624	hsa-miR-1244	CLIP-seq
MIRT827514	hsa-miR-1285	CLIP-seq
MIRT827625	hsa-miR-199a-3p	CLIP-seq
MIRT827626	hsa-miR-199b-3p	CLIP-seq
MIRT827530	hsa-miR-2355-5p	CLIP-seq
MIRT827627	hsa-miR-3129-5p	CLIP-seq
MIRT827628	hsa-miR-3153	CLIP-seq
MIRT827629	hsa-miR-3171	CLIP-seq
MIRT827539	hsa-miR-3187-5p	CLIP-seq
MIRT827545	hsa-miR-3615	CLIP-seq
MIRT827630	hsa-miR-3679-3p	CLIP-seq
MIRT827562	hsa-miR-4286	CLIP-seq
MIRT827568	hsa-miR-4461	CLIP-seq
MIRT827631	hsa-miR-4528	CLIP-seq
MIRT827574	hsa-miR-4646-5p	CLIP-seq
MIRT827578	hsa-miR-4666-5p	CLIP-seq
MIRT827632	hsa-miR-4668-5p	CLIP-seq
MIRT827633	hsa-miR-4685-5p	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT827635	hsa-miR-539	CLIP-seq
MIRT827602	hsa-miR-542-5p	CLIP-seq
MIRT827607	hsa-miR-580	CLIP-seq
MIRT827612	hsa-miR-612	CLIP-seq
MIRT827515	hsa-miR-1343	CLIP-seq
MIRT1944856	hsa-miR-3150a-3p	CLIP-seq
MIRT1944857	hsa-miR-4433	CLIP-seq
MIRT1944858	hsa-miR-4659a-3p	CLIP-seq
MIRT1944859	hsa-miR-4659b-3p	CLIP-seq
MIRT827595	hsa-miR-503	CLIP-seq
MIRT827615	hsa-miR-646	CLIP-seq
MIRT1944860	hsa-miR-1245b-3p	CLIP-seq
MIRT1944861	hsa-miR-1258	CLIP-seq
MIRT1944862	hsa-miR-1267	CLIP-seq
MIRT1944863	hsa-miR-1273g	CLIP-seq
MIRT1944864	hsa-miR-1321	CLIP-seq
MIRT1944865	hsa-miR-140-3p	CLIP-seq
MIRT1944866	hsa-miR-147	CLIP-seq
MIRT1944867	hsa-miR-186	CLIP-seq
MIRT827527	hsa-miR-214	CLIP-seq
MIRT1944868	hsa-miR-3117-5p	CLIP-seq
MIRT1944869	hsa-miR-3124-3p	CLIP-seq
MIRT1944870	hsa-miR-3130-3p	CLIP-seq
MIRT1944871	hsa-miR-3133	CLIP-seq
MIRT1944872	hsa-miR-3154	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT1944873	hsa-miR-3179	CLIP-seq
MIRT827541	hsa-miR-3202	CLIP-seq
MIRT827548	hsa-miR-3619-5p	CLIP-seq
MIRT1944874	hsa-miR-3663-5p	CLIP-seq
MIRT1944875	hsa-miR-3911	CLIP-seq
MIRT827555	hsa-miR-3938	CLIP-seq
MIRT1944876	hsa-miR-3940-5p	CLIP-seq
MIRT1944877	hsa-miR-4266	CLIP-seq
MIRT1944878	hsa-miR-4270	CLIP-seq
MIRT827563	hsa-miR-4291	CLIP-seq
MIRT1944879	hsa-miR-4318	CLIP-seq
MIRT1944880	hsa-miR-4423-5p	CLIP-seq
MIRT1944881	hsa-miR-4441	CLIP-seq
MIRT1944882	hsa-miR-4507	CLIP-seq
MIRT1944883	hsa-miR-452	CLIP-seq
MIRT1944884	hsa-miR-4527	CLIP-seq
MIRT827577	hsa-miR-4663	CLIP-seq
MIRT1944885	hsa-miR-4676-3p	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT1944886	hsa-miR-4739	CLIP-seq
MIRT1944887	hsa-miR-4744	CLIP-seq
MIRT827586	hsa-miR-4747-5p	CLIP-seq
MIRT1944888	hsa-miR-4753-3p	CLIP-seq
MIRT1944889	hsa-miR-4756-5p	CLIP-seq
MIRT827590	hsa-miR-4779	CLIP-seq
MIRT1944890	hsa-miR-4793-3p	CLIP-seq
MIRT1944891	hsa-miR-485-5p	CLIP-seq
MIRT1944892	hsa-miR-548g	CLIP-seq
MIRT1944893	hsa-miR-556-5p	CLIP-seq
MIRT1944894	hsa-miR-587	CLIP-seq
MIRT1944895	hsa-miR-610	CLIP-seq
MIRT1944896	hsa-miR-644	CLIP-seq
MIRT1944897	hsa-miR-7	CLIP-seq
MIRT1944898	hsa-miR-760	CLIP-seq
MIRT827617	hsa-miR-761	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq
MIRT827623	hsa-miR-922	CLIP-seq
MIRT2183369	hsa-miR-103a	CLIP-seq
MIRT2183370	hsa-miR-107	CLIP-seq
MIRT2183371	hsa-miR-1231	CLIP-seq
MIRT827624	hsa-miR-1244	CLIP-seq
MIRT2183372	hsa-miR-1263	CLIP-seq
MIRT1944862	hsa-miR-1267	CLIP-seq
MIRT1944863	hsa-miR-1273g	CLIP-seq
MIRT2183373	hsa-miR-1279	CLIP-seq
MIRT827514	hsa-miR-1285	CLIP-seq
MIRT827515	hsa-miR-1343	CLIP-seq
MIRT2183374	hsa-miR-135a	CLIP-seq
MIRT2183375	hsa-miR-135b	CLIP-seq
MIRT827517	hsa-miR-15a	CLIP-seq
MIRT827518	hsa-miR-15b	CLIP-seq
MIRT827519	hsa-miR-16	CLIP-seq
MIRT827520	hsa-miR-181a	CLIP-seq
MIRT827521	hsa-miR-181b	CLIP-seq
MIRT827522	hsa-miR-181c	CLIP-seq
MIRT827523	hsa-miR-181d	CLIP-seq
MIRT827525	hsa-miR-195	CLIP-seq
MIRT827625	hsa-miR-199a-3p	CLIP-seq
MIRT827626	hsa-miR-199b-3p	CLIP-seq
MIRT2183376	hsa-miR-2054	CLIP-seq
MIRT2183377	hsa-miR-2115	CLIP-seq
MIRT827528	hsa-miR-218	CLIP-seq
MIRT827529	hsa-miR-223	CLIP-seq
MIRT1944868	hsa-miR-3117-5p	CLIP-seq
MIRT2183378	hsa-miR-3120-5p	CLIP-seq
MIRT2183379	hsa-miR-3125	CLIP-seq
MIRT827627	hsa-miR-3129-5p	CLIP-seq
MIRT2183380	hsa-miR-3158-5p	CLIP-seq
MIRT2183381	hsa-miR-3166	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT827538	hsa-miR-3182	CLIP-seq
MIRT827539	hsa-miR-3187-5p	CLIP-seq
MIRT827540	hsa-miR-3189-3p	CLIP-seq
MIRT2183382	hsa-miR-342-3p	CLIP-seq
MIRT2183383	hsa-miR-3545-5p	CLIP-seq
MIRT827545	hsa-miR-3615	CLIP-seq
MIRT827546	hsa-miR-3616-3p	CLIP-seq
MIRT827547	hsa-miR-3617	CLIP-seq
MIRT2183384	hsa-miR-3622a-3p	CLIP-seq
MIRT2183385	hsa-miR-3622b-3p	CLIP-seq
MIRT2183386	hsa-miR-3657	CLIP-seq
MIRT1944874	hsa-miR-3663-5p	CLIP-seq
MIRT2183387	hsa-miR-3664-5p	CLIP-seq
MIRT2183388	hsa-miR-377	CLIP-seq
MIRT2183389	hsa-miR-378g	CLIP-seq
MIRT2183390	hsa-miR-3916	CLIP-seq
MIRT827557	hsa-miR-411	CLIP-seq
MIRT827558	hsa-miR-424	CLIP-seq
MIRT2183391	hsa-miR-425	CLIP-seq
MIRT827559	hsa-miR-4262	CLIP-seq
MIRT1944878	hsa-miR-4270	CLIP-seq
MIRT2183392	hsa-miR-4272	CLIP-seq
MIRT827560	hsa-miR-4274	CLIP-seq
MIRT2183393	hsa-miR-4279	CLIP-seq
MIRT2183394	hsa-miR-4282	CLIP-seq
MIRT2183395	hsa-miR-4288	CLIP-seq
MIRT2183396	hsa-miR-4301	CLIP-seq
MIRT827564	hsa-miR-4302	CLIP-seq
MIRT1944879	hsa-miR-4318	CLIP-seq
MIRT2183397	hsa-miR-4418	CLIP-seq
MIRT2183398	hsa-miR-4436b-5p	CLIP-seq
MIRT1944881	hsa-miR-4441	CLIP-seq
MIRT2183399	hsa-miR-4453	CLIP-seq
MIRT2183400	hsa-miR-4471	CLIP-seq
MIRT2183401	hsa-miR-4481	CLIP-seq
MIRT2183402	hsa-miR-4490	CLIP-seq
MIRT827570	hsa-miR-4506	CLIP-seq
MIRT827571	hsa-miR-4524	CLIP-seq
MIRT1944884	hsa-miR-4527	CLIP-seq
MIRT2183403	hsa-miR-4538	CLIP-seq
MIRT2183404	hsa-miR-4539	CLIP-seq
MIRT827572	hsa-miR-4640-5p	CLIP-seq
MIRT1944858	hsa-miR-4659a-3p	CLIP-seq
MIRT1944859	hsa-miR-4659b-3p	CLIP-seq
MIRT2183405	hsa-miR-466	CLIP-seq
MIRT2183406	hsa-miR-4660	CLIP-seq
MIRT2183407	hsa-miR-4661-5p	CLIP-seq
MIRT827577	hsa-miR-4663	CLIP-seq
MIRT827578	hsa-miR-4666-5p	CLIP-seq
MIRT2183408	hsa-miR-4669	CLIP-seq
MIRT2183409	hsa-miR-4680-5p	CLIP-seq
MIRT827633	hsa-miR-4685-5p	CLIP-seq
MIRT827579	hsa-miR-4697-3p	CLIP-seq
MIRT2183410	hsa-miR-4712-3p	CLIP-seq
MIRT827581	hsa-miR-4719	CLIP-seq
MIRT827582	hsa-miR-4721	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827585	hsa-miR-4726-5p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT2183411	hsa-miR-4745-5p	CLIP-seq
MIRT2183412	hsa-miR-4758-5p	CLIP-seq
MIRT827587	hsa-miR-4762-3p	CLIP-seq
MIRT827589	hsa-miR-4766-5p	CLIP-seq
MIRT2183413	hsa-miR-4771	CLIP-seq
MIRT2183414	hsa-miR-4774-5p	CLIP-seq
MIRT2183415	hsa-miR-4786-3p	CLIP-seq
MIRT2183416	hsa-miR-4793-5p	CLIP-seq
MIRT827593	hsa-miR-497	CLIP-seq
MIRT827594	hsa-miR-499a-5p	CLIP-seq
MIRT827595	hsa-miR-503	CLIP-seq
MIRT2183417	hsa-miR-505	CLIP-seq
MIRT2183418	hsa-miR-509-3-5p	CLIP-seq
MIRT2183419	hsa-miR-509-5p	CLIP-seq
MIRT827635	hsa-miR-539	CLIP-seq
MIRT827602	hsa-miR-542-5p	CLIP-seq
MIRT827603	hsa-miR-543	CLIP-seq
MIRT2183420	hsa-miR-545	CLIP-seq
MIRT2183421	hsa-miR-548ac	CLIP-seq
MIRT2183422	hsa-miR-548d-3p	CLIP-seq
MIRT2183423	hsa-miR-548z	CLIP-seq
MIRT827606	hsa-miR-556-3p	CLIP-seq
MIRT827607	hsa-miR-580	CLIP-seq
MIRT827608	hsa-miR-583	CLIP-seq
MIRT827609	hsa-miR-584	CLIP-seq
MIRT2183424	hsa-miR-609	CLIP-seq
MIRT827612	hsa-miR-612	CLIP-seq
MIRT2183425	hsa-miR-632	CLIP-seq
MIRT2183426	hsa-miR-633	CLIP-seq
MIRT827614	hsa-miR-641	CLIP-seq
MIRT827615	hsa-miR-646	CLIP-seq
MIRT2183427	hsa-miR-885-3p	CLIP-seq
MIRT827621	hsa-miR-891b	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq
MIRT1944860	hsa-miR-1245b-3p	CLIP-seq
MIRT1944862	hsa-miR-1267	CLIP-seq
MIRT1944863	hsa-miR-1273g	CLIP-seq
MIRT827514	hsa-miR-1285	CLIP-seq
MIRT827515	hsa-miR-1343	CLIP-seq
MIRT1944865	hsa-miR-140-3p	CLIP-seq
MIRT1944866	hsa-miR-147	CLIP-seq
MIRT1944867	hsa-miR-186	CLIP-seq
MIRT1944868	hsa-miR-3117-5p	CLIP-seq
MIRT1944871	hsa-miR-3133	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT827539	hsa-miR-3187-5p	CLIP-seq
MIRT1944874	hsa-miR-3663-5p	CLIP-seq
MIRT1944875	hsa-miR-3911	CLIP-seq
MIRT827560	hsa-miR-4274	CLIP-seq
MIRT827564	hsa-miR-4302	CLIP-seq
MIRT1944879	hsa-miR-4318	CLIP-seq
MIRT827570	hsa-miR-4506	CLIP-seq
MIRT1944883	hsa-miR-452	CLIP-seq
MIRT1944884	hsa-miR-4527	CLIP-seq
MIRT827577	hsa-miR-4663	CLIP-seq
MIRT1944885	hsa-miR-4676-3p	CLIP-seq
MIRT827579	hsa-miR-4697-3p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT1944887	hsa-miR-4744	CLIP-seq
MIRT1944892	hsa-miR-548g	CLIP-seq
MIRT1944893	hsa-miR-556-5p	CLIP-seq
MIRT1944895	hsa-miR-610	CLIP-seq
MIRT827612	hsa-miR-612	CLIP-seq
MIRT1944896	hsa-miR-644	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq
MIRT827515	hsa-miR-1343	CLIP-seq
MIRT827528	hsa-miR-218	CLIP-seq
MIRT827529	hsa-miR-223	CLIP-seq
MIRT2183380	hsa-miR-3158-5p	CLIP-seq
MIRT2183381	hsa-miR-3166	CLIP-seq
MIRT827542	hsa-miR-330-3p	CLIP-seq
MIRT2183386	hsa-miR-3657	CLIP-seq
MIRT2435825	hsa-miR-371-5p	CLIP-seq
MIRT2435826	hsa-miR-371b-5p	CLIP-seq
MIRT827557	hsa-miR-411	CLIP-seq
MIRT827560	hsa-miR-4274	CLIP-seq
MIRT2435827	hsa-miR-4294	CLIP-seq
MIRT2183397	hsa-miR-4418	CLIP-seq
MIRT1944857	hsa-miR-4433	CLIP-seq
MIRT827577	hsa-miR-4663	CLIP-seq
MIRT2183408	hsa-miR-4669	CLIP-seq
MIRT2183413	hsa-miR-4771	CLIP-seq
MIRT2183418	hsa-miR-509-3-5p	CLIP-seq
MIRT2183419	hsa-miR-509-5p	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq
MIRT2444927	hsa-miR-1237	CLIP-seq
MIRT2444928	hsa-miR-200b	CLIP-seq
MIRT2444929	hsa-miR-200c	CLIP-seq
MIRT2444930	hsa-miR-2276	CLIP-seq
MIRT2444931	hsa-miR-2682	CLIP-seq
MIRT2444932	hsa-miR-3157-3p	CLIP-seq
MIRT2444933	hsa-miR-429	CLIP-seq
MIRT2444934	hsa-miR-4328	CLIP-seq
MIRT1944857	hsa-miR-4433	CLIP-seq
MIRT2444935	hsa-miR-4455	CLIP-seq
MIRT2444936	hsa-miR-449c	CLIP-seq
MIRT2444937	hsa-miR-4772-3p	CLIP-seq
MIRT2444938	hsa-miR-544	CLIP-seq
MIRT2183424	hsa-miR-609	CLIP-seq
MIRT2444939	hsa-miR-874	CLIP-seq
MIRT2444940	hsa-miR-938	CLIP-seq
MIRT2444931	hsa-miR-2682	CLIP-seq
MIRT2444934	hsa-miR-4328	CLIP-seq
MIRT1944857	hsa-miR-4433	CLIP-seq
MIRT2444936	hsa-miR-449c	CLIP-seq
MIRT2183369	hsa-miR-103a	CLIP-seq
MIRT2183370	hsa-miR-107	CLIP-seq
MIRT2444927	hsa-miR-1237	CLIP-seq
MIRT1944860	hsa-miR-1245b-3p	CLIP-seq
MIRT1944861	hsa-miR-1258	CLIP-seq
MIRT1944862	hsa-miR-1267	CLIP-seq
MIRT1944863	hsa-miR-1273g	CLIP-seq
MIRT2487024	hsa-miR-1284	CLIP-seq
MIRT2487025	hsa-miR-1301	CLIP-seq
MIRT1944864	hsa-miR-1321	CLIP-seq
MIRT2487026	hsa-miR-138	CLIP-seq
MIRT1944865	hsa-miR-140-3p	CLIP-seq
MIRT2487027	hsa-miR-141	CLIP-seq
MIRT827516	hsa-miR-145	CLIP-seq
MIRT1944866	hsa-miR-147	CLIP-seq
MIRT827520	hsa-miR-181a	CLIP-seq
MIRT827521	hsa-miR-181b	CLIP-seq
MIRT827522	hsa-miR-181c	CLIP-seq
MIRT827523	hsa-miR-181d	CLIP-seq
MIRT2487028	hsa-miR-1825	CLIP-seq
MIRT1944867	hsa-miR-186	CLIP-seq
MIRT2487029	hsa-miR-187	CLIP-seq
MIRT2487030	hsa-miR-199a-5p	CLIP-seq
MIRT2487031	hsa-miR-199b-5p	CLIP-seq
MIRT2487032	hsa-miR-200a	CLIP-seq
MIRT2444928	hsa-miR-200b	CLIP-seq
MIRT2444929	hsa-miR-200c	CLIP-seq
MIRT2487033	hsa-miR-205	CLIP-seq
MIRT2444930	hsa-miR-2276	CLIP-seq
MIRT2487034	hsa-miR-3064-3p	CLIP-seq
MIRT1944868	hsa-miR-3117-5p	CLIP-seq
MIRT1944870	hsa-miR-3130-3p	CLIP-seq
MIRT1944871	hsa-miR-3133	CLIP-seq
MIRT1944872	hsa-miR-3154	CLIP-seq
MIRT2444932	hsa-miR-3157-3p	CLIP-seq
MIRT2487035	hsa-miR-3157-5p	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT1944873	hsa-miR-3179	CLIP-seq
MIRT827541	hsa-miR-3202	CLIP-seq
MIRT2487036	hsa-miR-329	CLIP-seq
MIRT2487037	hsa-miR-3591-3p	CLIP-seq
MIRT2487038	hsa-miR-3614-5p	CLIP-seq
MIRT2487039	hsa-miR-362-3p	CLIP-seq
MIRT2487040	hsa-miR-3653	CLIP-seq
MIRT2487041	hsa-miR-3655	CLIP-seq
MIRT2487042	hsa-miR-3658	CLIP-seq
MIRT1944874	hsa-miR-3663-5p	CLIP-seq
MIRT827552	hsa-miR-3691-3p	CLIP-seq
MIRT2487043	hsa-miR-3910	CLIP-seq
MIRT1944875	hsa-miR-3911	CLIP-seq
MIRT2487044	hsa-miR-3925-3p	CLIP-seq
MIRT2487045	hsa-miR-3936	CLIP-seq
MIRT827555	hsa-miR-3938	CLIP-seq
MIRT2487046	hsa-miR-3941	CLIP-seq
MIRT2487047	hsa-miR-3944-5p	CLIP-seq
MIRT2487048	hsa-miR-3975	CLIP-seq
MIRT2487049	hsa-miR-4259	CLIP-seq
MIRT827559	hsa-miR-4262	CLIP-seq
MIRT1944877	hsa-miR-4266	CLIP-seq
MIRT1944878	hsa-miR-4270	CLIP-seq
MIRT827561	hsa-miR-4276	CLIP-seq
MIRT2487050	hsa-miR-4283	CLIP-seq
MIRT2444933	hsa-miR-429	CLIP-seq
MIRT827564	hsa-miR-4302	CLIP-seq
MIRT2487051	hsa-miR-4311	CLIP-seq
MIRT1944879	hsa-miR-4318	CLIP-seq
MIRT2487052	hsa-miR-4421	CLIP-seq
MIRT1944881	hsa-miR-4441	CLIP-seq
MIRT2444935	hsa-miR-4455	CLIP-seq
MIRT2487053	hsa-miR-4489	CLIP-seq
MIRT1944883	hsa-miR-452	CLIP-seq
MIRT1944884	hsa-miR-4527	CLIP-seq
MIRT2487054	hsa-miR-4646-3p	CLIP-seq
MIRT2487055	hsa-miR-4656	CLIP-seq
MIRT1944885	hsa-miR-4676-3p	CLIP-seq
MIRT2487056	hsa-miR-4708-3p	CLIP-seq
MIRT2487057	hsa-miR-4715-5p	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT1944886	hsa-miR-4739	CLIP-seq
MIRT1944887	hsa-miR-4744	CLIP-seq
MIRT827586	hsa-miR-4747-5p	CLIP-seq
MIRT1944889	hsa-miR-4756-5p	CLIP-seq
MIRT2444937	hsa-miR-4772-3p	CLIP-seq
MIRT827590	hsa-miR-4779	CLIP-seq
MIRT1944890	hsa-miR-4793-3p	CLIP-seq
MIRT2487058	hsa-miR-4797-5p	CLIP-seq
MIRT1944891	hsa-miR-485-5p	CLIP-seq
MIRT2487059	hsa-miR-5047	CLIP-seq
MIRT2487060	hsa-miR-511	CLIP-seq
MIRT2444938	hsa-miR-544	CLIP-seq
MIRT2183420	hsa-miR-545	CLIP-seq
MIRT1944892	hsa-miR-548g	CLIP-seq
MIRT1944893	hsa-miR-556-5p	CLIP-seq
MIRT2487061	hsa-miR-562	CLIP-seq
MIRT2487062	hsa-miR-578	CLIP-seq
MIRT2487063	hsa-miR-581	CLIP-seq
MIRT2487064	hsa-miR-603	CLIP-seq
MIRT2183424	hsa-miR-609	CLIP-seq
MIRT1944895	hsa-miR-610	CLIP-seq
MIRT1944896	hsa-miR-644	CLIP-seq
MIRT2487065	hsa-miR-648	CLIP-seq
MIRT827616	hsa-miR-661	CLIP-seq
MIRT1944897	hsa-miR-7	CLIP-seq
MIRT1944898	hsa-miR-760	CLIP-seq
MIRT2487066	hsa-miR-767-5p	CLIP-seq
MIRT2444939	hsa-miR-874	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq
MIRT2444940	hsa-miR-938	CLIP-seq
MIRT2183369	hsa-miR-103a	CLIP-seq
MIRT2183370	hsa-miR-107	CLIP-seq
MIRT1944860	hsa-miR-1245b-3p	CLIP-seq
MIRT1944861	hsa-miR-1258	CLIP-seq
MIRT1944862	hsa-miR-1267	CLIP-seq
MIRT1944863	hsa-miR-1273g	CLIP-seq
MIRT2487025	hsa-miR-1301	CLIP-seq
MIRT1944864	hsa-miR-1321	CLIP-seq
MIRT2487026	hsa-miR-138	CLIP-seq
MIRT1944865	hsa-miR-140-3p	CLIP-seq
MIRT2487027	hsa-miR-141	CLIP-seq
MIRT2676228	hsa-miR-143	CLIP-seq
MIRT1944866	hsa-miR-147	CLIP-seq
MIRT2487028	hsa-miR-1825	CLIP-seq
MIRT1944867	hsa-miR-186	CLIP-seq
MIRT2487029	hsa-miR-187	CLIP-seq
MIRT2487030	hsa-miR-199a-5p	CLIP-seq
MIRT2487031	hsa-miR-199b-5p	CLIP-seq
MIRT2487032	hsa-miR-200a	CLIP-seq
MIRT2487033	hsa-miR-205	CLIP-seq
MIRT2487034	hsa-miR-3064-3p	CLIP-seq
MIRT1944868	hsa-miR-3117-5p	CLIP-seq
MIRT1944869	hsa-miR-3124-3p	CLIP-seq
MIRT1944870	hsa-miR-3130-3p	CLIP-seq
MIRT1944871	hsa-miR-3133	CLIP-seq
MIRT2676229	hsa-miR-3145-3p	CLIP-seq
MIRT1944872	hsa-miR-3154	CLIP-seq
MIRT2487035	hsa-miR-3157-5p	CLIP-seq
MIRT827535	hsa-miR-3173-3p	CLIP-seq
MIRT1944873	hsa-miR-3179	CLIP-seq
MIRT827541	hsa-miR-3202	CLIP-seq
MIRT2487036	hsa-miR-329	CLIP-seq
MIRT2487037	hsa-miR-3591-3p	CLIP-seq
MIRT2487038	hsa-miR-3614-5p	CLIP-seq
MIRT2487039	hsa-miR-362-3p	CLIP-seq
MIRT2487041	hsa-miR-3655	CLIP-seq
MIRT1944874	hsa-miR-3663-5p	CLIP-seq
MIRT2676230	hsa-miR-3682-3p	CLIP-seq
MIRT827552	hsa-miR-3691-3p	CLIP-seq
MIRT2487043	hsa-miR-3910	CLIP-seq
MIRT1944875	hsa-miR-3911	CLIP-seq
MIRT2487044	hsa-miR-3925-3p	CLIP-seq
MIRT2487045	hsa-miR-3936	CLIP-seq
MIRT827555	hsa-miR-3938	CLIP-seq
MIRT2487046	hsa-miR-3941	CLIP-seq
MIRT2487047	hsa-miR-3944-5p	CLIP-seq
MIRT2676231	hsa-miR-412	CLIP-seq
MIRT2487049	hsa-miR-4259	CLIP-seq
MIRT1944877	hsa-miR-4266	CLIP-seq
MIRT1944878	hsa-miR-4270	CLIP-seq
MIRT827561	hsa-miR-4276	CLIP-seq
MIRT2487050	hsa-miR-4283	CLIP-seq
MIRT827564	hsa-miR-4302	CLIP-seq
MIRT827566	hsa-miR-4310	CLIP-seq
MIRT1944879	hsa-miR-4318	CLIP-seq
MIRT2676232	hsa-miR-4420	CLIP-seq
MIRT1944881	hsa-miR-4441	CLIP-seq
MIRT2676233	hsa-miR-4462	CLIP-seq
MIRT2487053	hsa-miR-4489	CLIP-seq
MIRT1944883	hsa-miR-452	CLIP-seq
MIRT1944884	hsa-miR-4527	CLIP-seq
MIRT2487055	hsa-miR-4656	CLIP-seq
MIRT1944885	hsa-miR-4676-3p	CLIP-seq
MIRT2487056	hsa-miR-4708-3p	CLIP-seq
MIRT2487057	hsa-miR-4715-5p	CLIP-seq
MIRT2676234	hsa-miR-4724-5p	CLIP-seq
MIRT827584	hsa-miR-4725-3p	CLIP-seq
MIRT827634	hsa-miR-4738-3p	CLIP-seq
MIRT1944886	hsa-miR-4739	CLIP-seq
MIRT1944887	hsa-miR-4744	CLIP-seq
MIRT827586	hsa-miR-4747-5p	CLIP-seq
MIRT1944888	hsa-miR-4753-3p	CLIP-seq
MIRT1944889	hsa-miR-4756-5p	CLIP-seq
MIRT2676235	hsa-miR-4770	CLIP-seq
MIRT827590	hsa-miR-4779	CLIP-seq
MIRT2676236	hsa-miR-4781-3p	CLIP-seq
MIRT1944891	hsa-miR-485-5p	CLIP-seq
MIRT2487059	hsa-miR-5047	CLIP-seq
MIRT2183420	hsa-miR-545	CLIP-seq
MIRT1944892	hsa-miR-548g	CLIP-seq
MIRT1944893	hsa-miR-556-5p	CLIP-seq
MIRT2487061	hsa-miR-562	CLIP-seq
MIRT2487064	hsa-miR-603	CLIP-seq
MIRT1944895	hsa-miR-610	CLIP-seq
MIRT1944896	hsa-miR-644	CLIP-seq
MIRT2487065	hsa-miR-648	CLIP-seq
MIRT827616	hsa-miR-661	CLIP-seq
MIRT1944897	hsa-miR-7	CLIP-seq
MIRT1944898	hsa-miR-760	CLIP-seq
MIRT2487066	hsa-miR-767-5p	CLIP-seq
MIRT1944899	hsa-miR-892a	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SMAD4	Repression	14988407

Show/Hide all (68)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000045	Process	Autophagosome assembly	IDA	28890335
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	TAS	11001584
GO:0000209	Process	Protein polyubiquitination	IDA	12820959
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0000209	Process	Protein polyubiquitination	IMP	12820959
GO:0005515	Function	Protein binding	IPI	9859996, 11238952, 12609982, 12791267, 12820959, 12902344, 15070733, 15448698, 15917222, 16189514, 16371461, 16376880, 16865698, 16885022, 17318178, 17510365, 18354482, 18354483, 18521620, 18794143, 18805092, 19159283, 19196987, 19411070, 19615732, 19945379, 19966869, 20389281, 2053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IC	10066435
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006470	Process	Protein dephosphorylation	ISS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IDA	15448698
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	TAS	9990853
GO:0007040	Process	Lysosome organization	IDA	24448649
GO:0007165	Process	Signal transduction	TAS	9990853
GO:0008013	Function	Beta-catenin binding	IDA	12820959
GO:0008013	Function	Beta-catenin binding	IEA
GO:0010507	Process	Negative regulation of autophagy	IDA	32561715
GO:0010508	Process	Positive regulation of autophagy	IDA	22017875, 22017876
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016567	Process	Protein ubiquitination	IDA	16885022, 18354482
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IMP	21258371
GO:0016874	Function	Ligase activity	IEA
GO:0019005	Component	SCF ubiquitin ligase complex	IDA	12820959, 19966869
GO:0019005	Component	SCF ubiquitin ligase complex	IEA
GO:0030163	Process	Protein catabolic process	IEA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	22017875, 22017876, 22017877, 36608670
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IEA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	ISS	21911472
GO:0031648	Process	Protein destabilization	IEA
GO:0031648	Process	Protein destabilization	IMP	16885022
GO:0031669	Process	Cellular response to nutrient levels	IDA	32561715
GO:0033598	Process	Mammary gland epithelial cell proliferation	IEA
GO:0038061	Process	Non-canonical NF-kappaB signal transduction	IDA	12048232, 25038658
GO:0038061	Process	Non-canonical NF-kappaB signal transduction	IDA	10066435
GO:0038202	Process	TORC1 signaling	IDA	12087098
GO:0042752	Process	Regulation of circadian rhythm	IDA	15917222
GO:0042753	Process	Positive regulation of circadian rhythm	IEA
GO:0042753	Process	Positive regulation of circadian rhythm	ISS
GO:0043122	Process	Regulation of canonical NF-kappaB signal transduction	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	15917222
GO:0045309	Function	Protein phosphorylated amino acid binding	IEA
GO:0045862	Process	Positive regulation of proteolysis	IEA
GO:0045862	Process	Positive regulation of proteolysis	IMP	16885022
GO:0045879	Process	Negative regulation of smoothened signaling pathway	TAS	11001584
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	ISS
GO:0046983	Function	Protein dimerization activity	IEA
GO:0048511	Process	Rhythmic process	IEA
GO:0050852	Process	T cell receptor signaling pathway	IDA	8943371
GO:0050860	Process	Negative regulation of T cell receptor signaling pathway	IDA	38225265
GO:0050862	Process	Positive regulation of T cell receptor signaling pathway	IDA	38225265
GO:0051726	Process	Regulation of cell cycle	IEA
GO:0060444	Process	Branching involved in mammary gland duct morphogenesis	IEA
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IC	12820959
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IEA
GO:0061136	Process	Regulation of proteasomal protein catabolic process	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070534	Process	Protein K63-linked ubiquitination	IDA	38225265
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	38225265
GO:0070936	Process	Protein K48-linked ubiquitination	IEA
GO:1904262	Process	Negative regulation of TORC1 signaling	IDA	22017875, 22017876
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IDA	10066435, 11158290, 12820959, 22017875, 22017876, 22017877, 33110214, 36608670
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IEA
GO:1990757	Function	Ubiquitin ligase activator activity	IDA	12820959

MIM	HGNC	e!Ensembl
603482	1144	ENSG00000166167

Q9Y297

Protein name

F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)

Protein function

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:10066435, PubMed:10497169, PubMed:10644755

PDB

1P22 , 2P64 , 6M90 , 6M91 , 6M92 , 6M93 , 6M94 , 6TTU

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12125	Beta-TrCP_D	139 → 177	D domain of beta-TrCP	Domain
PF12937	F-box-like	183 → 231	F-box-like	Domain
PF00400	WD40	288 → 329	WD domain, G-beta repeat	Repeat
PF00400	WD40	333 → 369	WD domain, G-beta repeat	Repeat
PF00400	WD40	416 → 452	WD domain, G-beta repeat	Repeat
PF00400	WD40	456 → 492	WD domain, G-beta repeat	Repeat
PF00400	WD40	496 → 532	WD domain, G-beta repeat	Repeat
PF00400	WD40	546 → 581	WD domain, G-beta repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.

Sequence

MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDC
NNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIV
PKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDF
ITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWR
GLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRS
ETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGS
SDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRR
VLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVV
SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPR
APAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTY
TYISR

Sequence length

605

Interactions

View interactions

	KEGG		Reactome
	Oocyte meiosis Ubiquitin mediated proteolysis Cellular senescence Wnt signaling pathway Hedgehog signaling pathway Hippo signaling pathway Circadian rhythm Shigellosis Human immunodeficiency virus 1 infection		Activation of NF-kappaB in B cells Prolactin receptor signaling SCF-beta-TrCP mediated degradation of Emi1 Vpu mediated degradation of CD4 Degradation of beta-catenin by the destruction complex Downstream TCR signaling Regulation of PLK1 Activity at G2/M Transition FCERI mediated NF-kB activation Deactivation of the beta-catenin transactivating complex Dectin-1 mediated noncanonical NF-kB signaling CLEC7A (Dectin-1) signaling Degradation of GLI1 by the proteasome GLI3 is processed to GLI3R by the proteasome NIK-->noncanonical NF-kB signaling MAP3K8 (TPL2)-dependent MAPK1/3 activation Neddylation Interleukin-1 signaling Antigen processing: Ubiquitination & Proteasome degradation

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BTRC-related disorder	Benign; Likely benign; Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CROHN'S DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DESBUQUOIS SYNDROME	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INFLAMMATORY BOWEL DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RESTLESS LEGS SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULCERATIVE COLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (67)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenomatous Polyposis Coli	Multiple polyposis syndrome	LHGDN	19061640		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenomatous Polyposis Coli	Multiple polyposis syndrome	BEFREE	22751121		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adult Diffuse Large B-Cell Lymphoma	B-cell Lymphoma	BEFREE	31731887		★★★★★ ★☆☆☆☆ Found in Text Mining only
Aniridia	Aniridia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	21454620		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	26003292		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	23416973	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	28855742, 32462972, 36194598	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	32462972, 36822623	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	25311538, 36169173, 36822623	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Merkel Cell	Merkel cell carcinoma	Pubtator	30689667, 35336880	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	18372914, 28090088, 30266897		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	23546975	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Basal Cell	Carcinoma	BEFREE	12898158		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	23546975		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	15735746		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	15292388, 27417709		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	BEFREE	28499756		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	29655866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diffuse Large B-Cell Lymphoma	Diffuse Lymphoma	BEFREE	31731887		★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down syndrome	Pubtator	27807027	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectrodactyly	Ectrodactyly	ORPHANET_DG	16691619, 24115638		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ectrodactyly	Ectrodactyly	Pubtator	30622331	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	23546975		★★★★★ ★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	35913453, 37038094	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	21454620		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	21454620		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	28928851		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	33628829	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatoblastoma	Hepatoblastoma	BEFREE	15958610		★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington Disease	BEFREE	20531388		★★★★★ ★☆☆☆☆ Found in Text Mining only
Isolated split hand-split foot malformation	Isolated Split Hand-Split Foot Malformation	Orphanet			★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	19931512, 26004137		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	LHGDN	18372914		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	15753389, 26003292		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	28063214		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	18372914, 28090088, 30266897		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	17295679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24318128, 25632159, 28092836, 30266897		★★★★★ ★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	BEFREE	12898158		★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	LHGDN	12124804		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	17001349, 21829575, 28499756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	28499756		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma Cutaneous Malignant	Melanoma	Pubtator	28499756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	BEFREE	30250603		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	26497204		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	26497204, 36199071	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12898158, 15292388, 15735746, 21454620, 25632159, 26009993, 27854312, 28090088		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	21523764		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	21523764	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroectodermal Tumor, Primitive	Neuroectodermal Tumors	BEFREE	12898158		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oligodactyly	Oligodactyly	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	36199080	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	15855639	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	22711876		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	LHGDN	16651270		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	35562348	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	27476970		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorineural Hearing Loss (disorder)	Hearing Loss	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Sleep Disorders	Sleep Disorders	BEFREE	29856966		★★★★★ ★☆☆☆☆ Found in Text Mining only
SPLIT-HAND/FOOT MALFORMATION 3	Split-Hand-Foot Malformation	BEFREE	16691619		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	29650964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	17295679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach Neoplasms	LHGDN	17295679		★★★★★ ★☆☆☆☆ Found in Text Mining only
Syndactyly of fingers	Syndactyly of fingers	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple Negative Breast Neoplasms	BEFREE	25721419		★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	34197030	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase)