Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	8939
Gene name	Far upstream element binding protein 3
Gene symbol	FUBP3
Synonyms (NCBI Gene)	FBP3
Chromosome	9
Chromosome location	9q34.11-q34.12

184

Show/Hide all (184)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020823	hsa-miR-155-5p	Proteomics	18668040
MIRT023861	hsa-miR-1-3p	Proteomics	18668040
MIRT045868	hsa-miR-128-3p	CLASH	23622248
MIRT1006030	hsa-miR-101	CLIP-seq
MIRT1006031	hsa-miR-1279	CLIP-seq
MIRT1006032	hsa-miR-128	CLIP-seq
MIRT1006033	hsa-miR-1324	CLIP-seq
MIRT1006034	hsa-miR-139-5p	CLIP-seq
MIRT1006035	hsa-miR-141	CLIP-seq
MIRT1006036	hsa-miR-144	CLIP-seq
MIRT1006037	hsa-miR-1468	CLIP-seq
MIRT739651	hsa-miR-1827	CLIP-seq
MIRT1006038	hsa-miR-200a	CLIP-seq
MIRT1006039	hsa-miR-200b	CLIP-seq
MIRT1006040	hsa-miR-200c	CLIP-seq
MIRT739650	hsa-miR-203	CLIP-seq
MIRT1006041	hsa-miR-23a	CLIP-seq
MIRT1006042	hsa-miR-23b	CLIP-seq
MIRT1006043	hsa-miR-23c	CLIP-seq
MIRT1006044	hsa-miR-27a	CLIP-seq
MIRT1006045	hsa-miR-27b	CLIP-seq
MIRT1006046	hsa-miR-28-3p	CLIP-seq
MIRT1006047	hsa-miR-300	CLIP-seq
MIRT1006048	hsa-miR-30a	CLIP-seq
MIRT1006049	hsa-miR-30b	CLIP-seq
MIRT1006050	hsa-miR-30c	CLIP-seq
MIRT1006051	hsa-miR-30d	CLIP-seq
MIRT1006052	hsa-miR-30e	CLIP-seq
MIRT1006053	hsa-miR-3120-5p	CLIP-seq
MIRT1006054	hsa-miR-3143	CLIP-seq
MIRT1006055	hsa-miR-3152-3p	CLIP-seq
MIRT1006056	hsa-miR-338-5p	CLIP-seq
MIRT1006057	hsa-miR-3692	CLIP-seq
MIRT1006058	hsa-miR-374c	CLIP-seq
MIRT1006059	hsa-miR-381	CLIP-seq
MIRT739653	hsa-miR-3921	CLIP-seq
MIRT1006060	hsa-miR-409-3p	CLIP-seq
MIRT1006061	hsa-miR-4255	CLIP-seq
MIRT1006062	hsa-miR-4264	CLIP-seq
MIRT1006063	hsa-miR-4277	CLIP-seq
MIRT1006064	hsa-miR-429	CLIP-seq
MIRT1006065	hsa-miR-4302	CLIP-seq
MIRT1006066	hsa-miR-4328	CLIP-seq
MIRT1006067	hsa-miR-4528	CLIP-seq
MIRT739652	hsa-miR-4649-3p	CLIP-seq
MIRT739654	hsa-miR-4653-5p	CLIP-seq
MIRT1006068	hsa-miR-4666-3p	CLIP-seq
MIRT1006069	hsa-miR-4666-5p	CLIP-seq
MIRT1006070	hsa-miR-4704-5p	CLIP-seq
MIRT1006071	hsa-miR-4797-3p	CLIP-seq
MIRT1006072	hsa-miR-4799-5p	CLIP-seq
MIRT1006073	hsa-miR-498	CLIP-seq
MIRT1006074	hsa-miR-511	CLIP-seq
MIRT1006075	hsa-miR-513a-5p	CLIP-seq
MIRT1006076	hsa-miR-543	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT1006078	hsa-miR-548c-3p	CLIP-seq
MIRT1006079	hsa-miR-548n	CLIP-seq
MIRT1006080	hsa-miR-548t	CLIP-seq
MIRT1006081	hsa-miR-606	CLIP-seq
MIRT1006082	hsa-miR-633	CLIP-seq
MIRT739655	hsa-miR-653	CLIP-seq
MIRT1006083	hsa-miR-655	CLIP-seq
MIRT1006084	hsa-miR-656	CLIP-seq
MIRT1006085	hsa-miR-664	CLIP-seq
MIRT1006086	hsa-miR-875-3p	CLIP-seq
MIRT1006039	hsa-miR-200b	CLIP-seq
MIRT1006040	hsa-miR-200c	CLIP-seq
MIRT1006046	hsa-miR-28-3p	CLIP-seq
MIRT1006058	hsa-miR-374c	CLIP-seq
MIRT1006064	hsa-miR-429	CLIP-seq
MIRT1549082	hsa-miR-4760-3p	CLIP-seq
MIRT1006083	hsa-miR-655	CLIP-seq
MIRT1549083	hsa-miR-944	CLIP-seq
MIRT1006032	hsa-miR-128	CLIP-seq
MIRT1006036	hsa-miR-144	CLIP-seq
MIRT1006039	hsa-miR-200b	CLIP-seq
MIRT1006040	hsa-miR-200c	CLIP-seq
MIRT1006041	hsa-miR-23a	CLIP-seq
MIRT1006042	hsa-miR-23b	CLIP-seq
MIRT1006043	hsa-miR-23c	CLIP-seq
MIRT1006053	hsa-miR-3120-5p	CLIP-seq
MIRT1006055	hsa-miR-3152-3p	CLIP-seq
MIRT1006056	hsa-miR-338-5p	CLIP-seq
MIRT1006057	hsa-miR-3692	CLIP-seq
MIRT1006060	hsa-miR-409-3p	CLIP-seq
MIRT1006062	hsa-miR-4264	CLIP-seq
MIRT1006063	hsa-miR-4277	CLIP-seq
MIRT1006064	hsa-miR-429	CLIP-seq
MIRT1006065	hsa-miR-4302	CLIP-seq
MIRT1006066	hsa-miR-4328	CLIP-seq
MIRT1006071	hsa-miR-4797-3p	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT1006079	hsa-miR-548n	CLIP-seq
MIRT1006080	hsa-miR-548t	CLIP-seq
MIRT1006082	hsa-miR-633	CLIP-seq
MIRT1006085	hsa-miR-664	CLIP-seq
MIRT2231745	hsa-miR-1	CLIP-seq
MIRT1006030	hsa-miR-101	CLIP-seq
MIRT1006031	hsa-miR-1279	CLIP-seq
MIRT1006033	hsa-miR-1324	CLIP-seq
MIRT1006034	hsa-miR-139-5p	CLIP-seq
MIRT1006035	hsa-miR-141	CLIP-seq
MIRT1006036	hsa-miR-144	CLIP-seq
MIRT2231746	hsa-miR-188-5p	CLIP-seq
MIRT2231747	hsa-miR-191	CLIP-seq
MIRT1006038	hsa-miR-200a	CLIP-seq
MIRT1006039	hsa-miR-200b	CLIP-seq
MIRT1006040	hsa-miR-200c	CLIP-seq
MIRT2231748	hsa-miR-204	CLIP-seq
MIRT2231749	hsa-miR-206	CLIP-seq
MIRT2231750	hsa-miR-211	CLIP-seq
MIRT1006041	hsa-miR-23a	CLIP-seq
MIRT1006042	hsa-miR-23b	CLIP-seq
MIRT1006043	hsa-miR-23c	CLIP-seq
MIRT1006044	hsa-miR-27a	CLIP-seq
MIRT1006045	hsa-miR-27b	CLIP-seq
MIRT1006046	hsa-miR-28-3p	CLIP-seq
MIRT1006047	hsa-miR-300	CLIP-seq
MIRT1006048	hsa-miR-30a	CLIP-seq
MIRT1006049	hsa-miR-30b	CLIP-seq
MIRT1006050	hsa-miR-30c	CLIP-seq
MIRT1006051	hsa-miR-30d	CLIP-seq
MIRT1006052	hsa-miR-30e	CLIP-seq
MIRT1006056	hsa-miR-338-5p	CLIP-seq
MIRT1006058	hsa-miR-374c	CLIP-seq
MIRT1006059	hsa-miR-381	CLIP-seq
MIRT1006061	hsa-miR-4255	CLIP-seq
MIRT1006062	hsa-miR-4264	CLIP-seq
MIRT2231751	hsa-miR-4275	CLIP-seq
MIRT1006063	hsa-miR-4277	CLIP-seq
MIRT1006064	hsa-miR-429	CLIP-seq
MIRT1006066	hsa-miR-4328	CLIP-seq
MIRT2231752	hsa-miR-4464	CLIP-seq
MIRT2231753	hsa-miR-4495	CLIP-seq
MIRT2231754	hsa-miR-450b-5p	CLIP-seq
MIRT1006070	hsa-miR-4704-5p	CLIP-seq
MIRT2231755	hsa-miR-4709-5p	CLIP-seq
MIRT2231756	hsa-miR-4738-3p	CLIP-seq
MIRT2231757	hsa-miR-4748	CLIP-seq
MIRT1549082	hsa-miR-4760-3p	CLIP-seq
MIRT1006071	hsa-miR-4797-3p	CLIP-seq
MIRT1006075	hsa-miR-513a-5p	CLIP-seq
MIRT2231758	hsa-miR-518a-5p	CLIP-seq
MIRT2231759	hsa-miR-527	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT2231760	hsa-miR-548ac	CLIP-seq
MIRT2231761	hsa-miR-548ae	CLIP-seq
MIRT2231762	hsa-miR-548aj	CLIP-seq
MIRT2231763	hsa-miR-548am	CLIP-seq
MIRT1006078	hsa-miR-548c-3p	CLIP-seq
MIRT2231764	hsa-miR-548d-3p	CLIP-seq
MIRT2231765	hsa-miR-548g	CLIP-seq
MIRT2231766	hsa-miR-548x	CLIP-seq
MIRT2231767	hsa-miR-548z	CLIP-seq
MIRT2231768	hsa-miR-607	CLIP-seq
MIRT2231769	hsa-miR-613	CLIP-seq
MIRT1006082	hsa-miR-633	CLIP-seq
MIRT1006083	hsa-miR-655	CLIP-seq
MIRT1006084	hsa-miR-656	CLIP-seq
MIRT1006085	hsa-miR-664	CLIP-seq
MIRT1006086	hsa-miR-875-3p	CLIP-seq
MIRT1006031	hsa-miR-1279	CLIP-seq
MIRT1006032	hsa-miR-128	CLIP-seq
MIRT2231746	hsa-miR-188-5p	CLIP-seq
MIRT2231748	hsa-miR-204	CLIP-seq
MIRT2231750	hsa-miR-211	CLIP-seq
MIRT1006055	hsa-miR-3152-3p	CLIP-seq
MIRT1006057	hsa-miR-3692	CLIP-seq
MIRT1006060	hsa-miR-409-3p	CLIP-seq
MIRT1006065	hsa-miR-4302	CLIP-seq
MIRT1006079	hsa-miR-548n	CLIP-seq
MIRT1006080	hsa-miR-548t	CLIP-seq
MIRT1006081	hsa-miR-606	CLIP-seq
MIRT1006084	hsa-miR-656	CLIP-seq
MIRT1006086	hsa-miR-875-3p	CLIP-seq
MIRT2449930	hsa-miR-1197	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT2449930	hsa-miR-1197	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT2449930	hsa-miR-1197	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq
MIRT2449930	hsa-miR-1197	CLIP-seq
MIRT1006077	hsa-miR-548aa	CLIP-seq

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003697	Function	Single-stranded DNA binding	IDA	8940189
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003729	Function	MRNA binding	IBA
GO:0005515	Function	Protein binding	IPI	16713569, 25416956, 32296183, 39251607
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	19087307
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	8940189
GO:0005654	Component	Nucleoplasm	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	19087307
GO:0005840	Component	Ribosome	IEA
GO:0006351	Process	DNA-templated transcription	IDA	8940189
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008298	Process	Intracellular mRNA localization	IEA
GO:0010628	Process	Positive regulation of gene expression	IDA	19087307
GO:0016020	Component	Membrane	HDA	19946888
GO:0043025	Component	Neuronal cell body	IEA
GO:0043198	Component	Dendritic shaft	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	8940189
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8940183
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8940189

MIM	HGNC	e!Ensembl
603536	4005	ENSG00000107164

Q96I24

Protein name

Far upstream element-binding protein 3 (FUSE-binding protein 3)

Protein function

May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00013	KH_1	79 → 143	KH domain	Domain
PF00013	KH_1	164 → 230	KH domain	Domain
PF00013	KH_1	255 → 319	KH domain	Domain
PF00013	KH_1	356 → 423	KH domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in a number of cell lines.

Sequence

MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPL
DDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGI
PERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR
GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF
RGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERA
AQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT
VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQL
IDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGP
PAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSP
PDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ

Sequence length

572

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
UPPER AERODIGESTIVE TRACT NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	19087307	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	35413821	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glycosuria Renal	Renal glycosuria	Pubtator	19087307	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	21356256		★★★★★ ★☆☆☆☆ Found in Text Mining only

FUBP3 (far upstream element binding protein 3)