FUBP1 (far upstream element binding protein 1)

Gene

• Entrez ID: 8880
• Gene name: Far upstream element binding protein 1
• Gene symbol: FUBP1
• Synonyms (NCBI Gene): FBP, FUBP, hDH V
• Chromosome: 1
• Chromosome location: 1p31.1
• Summary: The protein encoded by this gene is a single stranded DNA-binding protein that binds to multiple DNA elements, including the far upstream element (FUSE) located upstream of c-myc. Binding to FUSE occurs on the non-coding strand, and is important to the re

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020591	hsa-miR-155-5p	Proteomics	18668040
MIRT023618	hsa-miR-1-3p	Proteomics	18668040
MIRT024616	hsa-miR-215-5p	Microarray	19074876
MIRT026246	hsa-miR-192-5p	Microarray	19074876
MIRT030728	hsa-miR-21-5p	Microarray	18591254
MIRT050458	hsa-miR-22-3p	CLASH	23622248
MIRT046588	hsa-miR-222-3p	CLASH	23622248
MIRT042947	hsa-miR-324-3p	CLASH	23622248
MIRT039813	hsa-miR-615-3p	CLASH	23622248
MIRT557748	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT557746	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT557747	hsa-miR-4787-3p	HITS-CLIP	21572407
MIRT557745	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT557744	hsa-let-7i-3p	HITS-CLIP	21572407
MIRT557748	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT557746	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT557747	hsa-miR-4787-3p	PAR-CLIP	21572407
MIRT557745	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT557744	hsa-let-7i-3p	PAR-CLIP	21572407
MIRT440607	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440607	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT557748	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT557746	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT557747	hsa-miR-4787-3p	HITS-CLIP	21572407
MIRT557745	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT557744	hsa-let-7i-3p	HITS-CLIP	21572407
MIRT557748	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT557746	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT557747	hsa-miR-4787-3p	PAR-CLIP	21572407
MIRT557745	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT557744	hsa-let-7i-3p	PAR-CLIP	21572407
MIRT1005946	hsa-miR-1183	CLIP-seq
MIRT1005947	hsa-miR-1208	CLIP-seq
MIRT1005948	hsa-miR-1297	CLIP-seq
MIRT1005949	hsa-miR-132	CLIP-seq
MIRT1005950	hsa-miR-15a	CLIP-seq
MIRT1005951	hsa-miR-15b	CLIP-seq
MIRT1005952	hsa-miR-16	CLIP-seq
MIRT1005953	hsa-miR-195	CLIP-seq
MIRT1005954	hsa-miR-200b	CLIP-seq
MIRT1005955	hsa-miR-200c	CLIP-seq
MIRT1005956	hsa-miR-2053	CLIP-seq
MIRT1005957	hsa-miR-21	CLIP-seq
MIRT1005958	hsa-miR-2110	CLIP-seq
MIRT1005959	hsa-miR-212	CLIP-seq
MIRT1005960	hsa-miR-217	CLIP-seq
MIRT1005961	hsa-miR-2276	CLIP-seq
MIRT1005962	hsa-miR-23a	CLIP-seq
MIRT1005963	hsa-miR-23b	CLIP-seq
MIRT1005964	hsa-miR-23c	CLIP-seq
MIRT1005965	hsa-miR-26a	CLIP-seq
MIRT1005966	hsa-miR-26b	CLIP-seq
MIRT1005967	hsa-miR-3074-3p	CLIP-seq
MIRT1005968	hsa-miR-3148	CLIP-seq
MIRT1005969	hsa-miR-3153	CLIP-seq
MIRT1005970	hsa-miR-3156-5p	CLIP-seq
MIRT1005971	hsa-miR-3163	CLIP-seq
MIRT1005972	hsa-miR-324-5p	CLIP-seq
MIRT1005973	hsa-miR-330-3p	CLIP-seq
MIRT1005974	hsa-miR-3609	CLIP-seq
MIRT1005975	hsa-miR-361-3p	CLIP-seq
MIRT1005976	hsa-miR-3653	CLIP-seq
MIRT1005977	hsa-miR-3658	CLIP-seq
MIRT1005978	hsa-miR-3679-3p	CLIP-seq
MIRT1005979	hsa-miR-3688-3p	CLIP-seq
MIRT1005980	hsa-miR-3924	CLIP-seq
MIRT1005981	hsa-miR-3977	CLIP-seq
MIRT1005982	hsa-miR-3978	CLIP-seq
MIRT1005983	hsa-miR-424	CLIP-seq
MIRT1005984	hsa-miR-4271	CLIP-seq
MIRT1005985	hsa-miR-429	CLIP-seq
MIRT1005986	hsa-miR-432	CLIP-seq
MIRT1005987	hsa-miR-4418	CLIP-seq
MIRT1005988	hsa-miR-4420	CLIP-seq
MIRT1005989	hsa-miR-4422	CLIP-seq
MIRT1005990	hsa-miR-4446-5p	CLIP-seq
MIRT1005991	hsa-miR-4459	CLIP-seq
MIRT1005992	hsa-miR-4465	CLIP-seq
MIRT1005993	hsa-miR-4511	CLIP-seq
MIRT1005994	hsa-miR-4524	CLIP-seq
MIRT1005995	hsa-miR-4633-5p	CLIP-seq
MIRT1005996	hsa-miR-4668-5p	CLIP-seq
MIRT1005997	hsa-miR-4691-5p	CLIP-seq
MIRT1005998	hsa-miR-4708-3p	CLIP-seq
MIRT1005999	hsa-miR-4717-3p	CLIP-seq
MIRT1006000	hsa-miR-4719	CLIP-seq
MIRT1006001	hsa-miR-4725-3p	CLIP-seq
MIRT1006002	hsa-miR-4729	CLIP-seq
MIRT1006003	hsa-miR-4742-3p	CLIP-seq
MIRT1006004	hsa-miR-4773	CLIP-seq
MIRT1006005	hsa-miR-4802-3p	CLIP-seq
MIRT1006006	hsa-miR-488	CLIP-seq
MIRT1006007	hsa-miR-495	CLIP-seq
MIRT1006008	hsa-miR-497	CLIP-seq
MIRT1006009	hsa-miR-503	CLIP-seq
MIRT1006010	hsa-miR-509-3-5p	CLIP-seq
MIRT1006011	hsa-miR-509-5p	CLIP-seq
MIRT1006012	hsa-miR-513a-3p	CLIP-seq
MIRT1006013	hsa-miR-548ae	CLIP-seq
MIRT1006014	hsa-miR-548ah	CLIP-seq
MIRT1006015	hsa-miR-548aj	CLIP-seq
MIRT1006016	hsa-miR-548am	CLIP-seq
MIRT1006017	hsa-miR-548b-3p	CLIP-seq
MIRT1006018	hsa-miR-548k	CLIP-seq
MIRT1006019	hsa-miR-548l	CLIP-seq
MIRT1006020	hsa-miR-548n	CLIP-seq
MIRT1006021	hsa-miR-548t	CLIP-seq
MIRT1006022	hsa-miR-548x	CLIP-seq
MIRT1006023	hsa-miR-552	CLIP-seq
MIRT1006024	hsa-miR-568	CLIP-seq
MIRT1006025	hsa-miR-569	CLIP-seq
MIRT1006026	hsa-miR-590-5p	CLIP-seq
MIRT1006027	hsa-miR-599	CLIP-seq
MIRT1006028	hsa-miR-625	CLIP-seq
MIRT1006029	hsa-miR-646	CLIP-seq
MIRT1005947	hsa-miR-1208	CLIP-seq
MIRT1998121	hsa-miR-155	CLIP-seq
MIRT1005956	hsa-miR-2053	CLIP-seq
MIRT1998122	hsa-miR-302f	CLIP-seq
MIRT1005967	hsa-miR-3074-3p	CLIP-seq
MIRT1005970	hsa-miR-3156-5p	CLIP-seq
MIRT1005972	hsa-miR-324-5p	CLIP-seq
MIRT1005973	hsa-miR-330-3p	CLIP-seq
MIRT1005974	hsa-miR-3609	CLIP-seq
MIRT1005988	hsa-miR-4420	CLIP-seq
MIRT1005989	hsa-miR-4422	CLIP-seq
MIRT1005991	hsa-miR-4459	CLIP-seq
MIRT1998123	hsa-miR-4672	CLIP-seq
MIRT1006000	hsa-miR-4719	CLIP-seq
MIRT1006002	hsa-miR-4729	CLIP-seq
MIRT1006012	hsa-miR-513a-3p	CLIP-seq
MIRT1998124	hsa-miR-518a-5p	CLIP-seq
MIRT1998125	hsa-miR-527	CLIP-seq
MIRT1006014	hsa-miR-548ah	CLIP-seq
MIRT1006018	hsa-miR-548k	CLIP-seq
MIRT1006019	hsa-miR-548l	CLIP-seq
MIRT1006020	hsa-miR-548n	CLIP-seq
MIRT1006021	hsa-miR-548t	CLIP-seq
MIRT1006025	hsa-miR-569	CLIP-seq
MIRT1998126	hsa-miR-579	CLIP-seq
MIRT2231734	hsa-miR-1	CLIP-seq
MIRT1005946	hsa-miR-1183	CLIP-seq
MIRT1005947	hsa-miR-1208	CLIP-seq
MIRT2231735	hsa-miR-1287	CLIP-seq
MIRT1005948	hsa-miR-1297	CLIP-seq
MIRT1005949	hsa-miR-132	CLIP-seq
MIRT1998121	hsa-miR-155	CLIP-seq
MIRT1005950	hsa-miR-15a	CLIP-seq
MIRT1005951	hsa-miR-15b	CLIP-seq
MIRT1005952	hsa-miR-16	CLIP-seq
MIRT1005953	hsa-miR-195	CLIP-seq
MIRT1005954	hsa-miR-200b	CLIP-seq
MIRT1005955	hsa-miR-200c	CLIP-seq
MIRT1005956	hsa-miR-2053	CLIP-seq
MIRT2231736	hsa-miR-206	CLIP-seq
MIRT1005957	hsa-miR-21	CLIP-seq
MIRT1005958	hsa-miR-2110	CLIP-seq
MIRT1005959	hsa-miR-212	CLIP-seq
MIRT1005965	hsa-miR-26a	CLIP-seq
MIRT1005966	hsa-miR-26b	CLIP-seq
MIRT1998122	hsa-miR-302f	CLIP-seq
MIRT1005967	hsa-miR-3074-3p	CLIP-seq
MIRT2231737	hsa-miR-3135b	CLIP-seq
MIRT1005968	hsa-miR-3148	CLIP-seq
MIRT1005969	hsa-miR-3153	CLIP-seq
MIRT1005970	hsa-miR-3156-5p	CLIP-seq
MIRT1005971	hsa-miR-3163	CLIP-seq
MIRT2231738	hsa-miR-3177-5p	CLIP-seq
MIRT1005972	hsa-miR-324-5p	CLIP-seq
MIRT1005973	hsa-miR-330-3p	CLIP-seq
MIRT2231739	hsa-miR-3545-5p	CLIP-seq
MIRT1005975	hsa-miR-361-3p	CLIP-seq
MIRT2231740	hsa-miR-3673	CLIP-seq
MIRT1005978	hsa-miR-3679-3p	CLIP-seq
MIRT1005979	hsa-miR-3688-3p	CLIP-seq
MIRT1005980	hsa-miR-3924	CLIP-seq
MIRT1005982	hsa-miR-3978	CLIP-seq
MIRT1005983	hsa-miR-424	CLIP-seq
MIRT1005984	hsa-miR-4271	CLIP-seq
MIRT1005985	hsa-miR-429	CLIP-seq
MIRT1005986	hsa-miR-432	CLIP-seq
MIRT1005988	hsa-miR-4420	CLIP-seq
MIRT1005989	hsa-miR-4422	CLIP-seq
MIRT2231741	hsa-miR-4436b-5p	CLIP-seq
MIRT1005990	hsa-miR-4446-5p	CLIP-seq
MIRT1005992	hsa-miR-4465	CLIP-seq
MIRT1005994	hsa-miR-4524	CLIP-seq
MIRT1005995	hsa-miR-4633-5p	CLIP-seq
MIRT1006000	hsa-miR-4719	CLIP-seq
MIRT1006001	hsa-miR-4725-3p	CLIP-seq
MIRT1006002	hsa-miR-4729	CLIP-seq
MIRT1006003	hsa-miR-4742-3p	CLIP-seq
MIRT2231742	hsa-miR-4766-5p	CLIP-seq
MIRT2231743	hsa-miR-494	CLIP-seq
MIRT1006007	hsa-miR-495	CLIP-seq
MIRT1006008	hsa-miR-497	CLIP-seq
MIRT1006009	hsa-miR-503	CLIP-seq
MIRT1006012	hsa-miR-513a-3p	CLIP-seq
MIRT1998124	hsa-miR-518a-5p	CLIP-seq
MIRT1998125	hsa-miR-527	CLIP-seq
MIRT1006013	hsa-miR-548ae	CLIP-seq
MIRT1006015	hsa-miR-548aj	CLIP-seq
MIRT1006016	hsa-miR-548am	CLIP-seq
MIRT1006022	hsa-miR-548x	CLIP-seq
MIRT1006023	hsa-miR-552	CLIP-seq
MIRT1006024	hsa-miR-568	CLIP-seq
MIRT1006025	hsa-miR-569	CLIP-seq
MIRT1006026	hsa-miR-590-5p	CLIP-seq
MIRT1006027	hsa-miR-599	CLIP-seq
MIRT2231744	hsa-miR-613	CLIP-seq
MIRT1006029	hsa-miR-646	CLIP-seq
MIRT1005947	hsa-miR-1208	CLIP-seq
MIRT2535757	hsa-miR-1252	CLIP-seq
MIRT2535758	hsa-miR-1279	CLIP-seq
MIRT2535759	hsa-miR-151-3p	CLIP-seq
MIRT1998121	hsa-miR-155	CLIP-seq
MIRT1005956	hsa-miR-2053	CLIP-seq
MIRT2535760	hsa-miR-2116	CLIP-seq
MIRT1005962	hsa-miR-23a	CLIP-seq
MIRT1005963	hsa-miR-23b	CLIP-seq
MIRT1005964	hsa-miR-23c	CLIP-seq
MIRT1998122	hsa-miR-302f	CLIP-seq
MIRT1005967	hsa-miR-3074-3p	CLIP-seq
MIRT1005968	hsa-miR-3148	CLIP-seq
MIRT1005971	hsa-miR-3163	CLIP-seq
MIRT2535761	hsa-miR-3200-5p	CLIP-seq
MIRT2535762	hsa-miR-329	CLIP-seq
MIRT1005973	hsa-miR-330-3p	CLIP-seq
MIRT2231739	hsa-miR-3545-5p	CLIP-seq
MIRT1005974	hsa-miR-3609	CLIP-seq
MIRT2535763	hsa-miR-362-3p	CLIP-seq
MIRT1005979	hsa-miR-3688-3p	CLIP-seq
MIRT2535764	hsa-miR-3941	CLIP-seq
MIRT1005981	hsa-miR-3977	CLIP-seq
MIRT2535765	hsa-miR-4282	CLIP-seq
MIRT2535766	hsa-miR-4289	CLIP-seq
MIRT2535767	hsa-miR-4328	CLIP-seq
MIRT1005988	hsa-miR-4420	CLIP-seq
MIRT1005989	hsa-miR-4422	CLIP-seq
MIRT1005991	hsa-miR-4459	CLIP-seq
MIRT2535768	hsa-miR-452	CLIP-seq
MIRT2535769	hsa-miR-4643	CLIP-seq
MIRT2535770	hsa-miR-4676-3p	CLIP-seq
MIRT2535771	hsa-miR-4677-5p	CLIP-seq
MIRT1005999	hsa-miR-4717-3p	CLIP-seq
MIRT1006000	hsa-miR-4719	CLIP-seq
MIRT1006002	hsa-miR-4729	CLIP-seq
MIRT2231742	hsa-miR-4766-5p	CLIP-seq
MIRT1006005	hsa-miR-4802-3p	CLIP-seq
MIRT1006006	hsa-miR-488	CLIP-seq
MIRT2231743	hsa-miR-494	CLIP-seq
MIRT1006012	hsa-miR-513a-3p	CLIP-seq
MIRT1998124	hsa-miR-518a-5p	CLIP-seq
MIRT1998125	hsa-miR-527	CLIP-seq
MIRT2535772	hsa-miR-548a-3p	CLIP-seq
MIRT1006013	hsa-miR-548ae	CLIP-seq
MIRT1006014	hsa-miR-548ah	CLIP-seq
MIRT1006015	hsa-miR-548aj	CLIP-seq
MIRT1006016	hsa-miR-548am	CLIP-seq
MIRT2535773	hsa-miR-548e	CLIP-seq
MIRT2535774	hsa-miR-548f	CLIP-seq
MIRT2535775	hsa-miR-548g	CLIP-seq
MIRT1006018	hsa-miR-548k	CLIP-seq
MIRT1006019	hsa-miR-548l	CLIP-seq
MIRT1006020	hsa-miR-548n	CLIP-seq
MIRT1006021	hsa-miR-548t	CLIP-seq
MIRT1006022	hsa-miR-548x	CLIP-seq
MIRT1006024	hsa-miR-568	CLIP-seq
MIRT1006025	hsa-miR-569	CLIP-seq
MIRT2535776	hsa-miR-570	CLIP-seq
MIRT2535777	hsa-miR-603	CLIP-seq
MIRT1005947	hsa-miR-1208	CLIP-seq
MIRT2535757	hsa-miR-1252	CLIP-seq
MIRT1998121	hsa-miR-155	CLIP-seq
MIRT1005956	hsa-miR-2053	CLIP-seq
MIRT2535760	hsa-miR-2116	CLIP-seq
MIRT1005962	hsa-miR-23a	CLIP-seq
MIRT1005963	hsa-miR-23b	CLIP-seq
MIRT1005964	hsa-miR-23c	CLIP-seq
MIRT1005967	hsa-miR-3074-3p	CLIP-seq
MIRT1005968	hsa-miR-3148	CLIP-seq
MIRT1005971	hsa-miR-3163	CLIP-seq
MIRT2535762	hsa-miR-329	CLIP-seq
MIRT1005973	hsa-miR-330-3p	CLIP-seq
MIRT2231739	hsa-miR-3545-5p	CLIP-seq
MIRT1005974	hsa-miR-3609	CLIP-seq
MIRT2535763	hsa-miR-362-3p	CLIP-seq
MIRT1005979	hsa-miR-3688-3p	CLIP-seq
MIRT2535764	hsa-miR-3941	CLIP-seq
MIRT1005981	hsa-miR-3977	CLIP-seq
MIRT2535766	hsa-miR-4289	CLIP-seq
MIRT2535767	hsa-miR-4328	CLIP-seq
MIRT1005988	hsa-miR-4420	CLIP-seq
MIRT1005989	hsa-miR-4422	CLIP-seq
MIRT1005991	hsa-miR-4459	CLIP-seq
MIRT2535769	hsa-miR-4643	CLIP-seq
MIRT2535771	hsa-miR-4677-5p	CLIP-seq
MIRT1005999	hsa-miR-4717-3p	CLIP-seq
MIRT1006000	hsa-miR-4719	CLIP-seq
MIRT1006002	hsa-miR-4729	CLIP-seq
MIRT1006005	hsa-miR-4802-3p	CLIP-seq
MIRT1006006	hsa-miR-488	CLIP-seq
MIRT2231743	hsa-miR-494	CLIP-seq
MIRT1006012	hsa-miR-513a-3p	CLIP-seq
MIRT2535772	hsa-miR-548a-3p	CLIP-seq
MIRT1006013	hsa-miR-548ae	CLIP-seq
MIRT1006014	hsa-miR-548ah	CLIP-seq
MIRT1006015	hsa-miR-548aj	CLIP-seq
MIRT1006016	hsa-miR-548am	CLIP-seq
MIRT2535773	hsa-miR-548e	CLIP-seq
MIRT2535774	hsa-miR-548f	CLIP-seq
MIRT2535775	hsa-miR-548g	CLIP-seq
MIRT1006018	hsa-miR-548k	CLIP-seq
MIRT1006019	hsa-miR-548l	CLIP-seq
MIRT1006020	hsa-miR-548n	CLIP-seq
MIRT1006021	hsa-miR-548t	CLIP-seq
MIRT1006022	hsa-miR-548x	CLIP-seq
MIRT1006024	hsa-miR-568	CLIP-seq
MIRT1006025	hsa-miR-569	CLIP-seq
MIRT2535777	hsa-miR-603	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0003697	Function	Single-stranded DNA binding	TAS	8125259
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003729	Function	MRNA binding	IBA
GO:0005515	Function	Protein binding	IPI	20711187, 21285945, 21779003, 21988832, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	19087307
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0010468	Process	Regulation of gene expression	TAS	8125259
GO:0010628	Process	Positive regulation of gene expression	IDA	19087307

Other IDs

• MIM: 603444
• HGNC: 4004
• e!Ensembl: ENSG00000162613

Protein

• UniProt ID: Q96AE4
• Protein name: Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V)
• Protein function: Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.
• PDB: 1J4W, 2KXH, 4LIJ, 6Y24, 6Y2C, 6Y2D, 8P25
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00013	KH_1	102 → 166	KH domain	Domain
  PF00013	KH_1	187 → 253	KH domain	Domain
  PF00013	KH_1	277 → 341	KH domain	Domain
  PF00013	KH_1	378 → 445	KH domain	Domain
  PF09005	DUF1897	572 → 599	Domain of unknown function (DUF1897)	Domain
  PF09005	DUF1897	602 → 626	Domain of unknown function (DUF1897)	Domain

• Sequence:

  MADYSTVPPPSSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGY
  GGQKRPLEDGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGRGG
  EQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHHG
  DGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLRITGD
  PYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNGEMIKK
  IQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRG
  RGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNA
  DPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLGPPVPHGPHGVPGPHGPPGPPGPGTP
  MGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTDPNSAAWAAY
  YAHYYQQQAQPPPAAPAGAPTTTQTNGQGDQQNPAPAGQVDYTKAWEEYYKKMGQAVPAP
  TGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPPAPQGQ

• Sequence length: 644

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast ductal adenocarcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Familial pancreatic carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hepatocellular carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUNG NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant lymphoma, large B-cell, diffuse	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenoma	Adenoma	BEFREE	25030436		★☆☆☆☆ Found in Text Mining only
Adult Oligodendroglioma	Oligodendroglioma	BEFREE	21817013, 24117486, 25943885		★☆☆☆☆ Found in Text Mining only
Anaplastic Oligodendroglioma	Anaplastic Oligodendroglioma	BEFREE	23071531, 28388591		★☆☆☆☆ Found in Text Mining only
Anemia, Hemolytic	Anemia	BEFREE	14766013		★☆☆☆☆ Found in Text Mining only
Arthrogryposis	Arthrogryposis multiplex congenita	BEFREE	14766013		★☆☆☆☆ Found in Text Mining only
Astrocytoma	Astrocytoma	BEFREE	22869205		★☆☆☆☆ Found in Text Mining only
Brain Neoplasms	Brain neoplasms	Pubtator	22869205	Associate	★☆☆☆☆ Found in Text Mining only
Brain Tumor, Primary	Brain Neoplasms	BEFREE	22588899		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	27157613		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	32626933	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25995247	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	28076379	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	25487856, 25995247, 26901106, 33954195	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	37910256	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Renal cell carcinoma	Pubtator	28076379	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29113212		★☆☆☆☆ Found in Text Mining only
Childhood Oligodendroglioma	Oligodendroglioma	BEFREE	21817013, 24117486, 25943885		★☆☆☆☆ Found in Text Mining only
Chordoma	Chordoma	BEFREE	28780352		★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	24966911		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	25030436, 29031818		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34288405	Stimulate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	35546072	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	28076379		★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	30035378		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	30035378		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	8530070		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	29113212		★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	26490982	Associate	★☆☆☆☆ Found in Text Mining only
Ganglioneuroblastoma	Ganglioneuroblastoma	BEFREE	31511046		★☆☆☆☆ Found in Text Mining only
Ganglioneuroma	Ganglioneuroma	BEFREE	31511046		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	36932454	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	22869205, 24117486		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	22869205, 26061751, 29272522, 34589661	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	CGI_DG			★☆☆☆☆ Found in Text Mining only
Hematological Disease	Hematological Disease	BEFREE	30343319		★☆☆☆☆ Found in Text Mining only
Hepatitis C	Hepatitis c	Pubtator	25995247	Associate	★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	30635626		★☆☆☆☆ Found in Text Mining only
Leukemia	Leukemia	Pubtator	8125259	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	30635626, 31467227		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	LHGDN	19003864		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	19637194, 25995247, 29031818, 29113212, 31587040		★☆☆☆☆ Found in Text Mining only
Liver neoplasms	Liver neoplasms	BEFREE	25995247		★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	32339054	Stimulate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	27157613		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	23338277, 31587040		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	30301530		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	27157613, 28667493		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29133573, 30301530, 30343319, 31511046		★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	27407063		★☆☆☆☆ Found in Text Mining only
Maturity onset diabetes mellitus in young	Mason type diabetes	BEFREE	8530070		★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy Duchenne	Duchenne muscular dystrophy	Pubtator	25662218	Associate	★☆☆☆☆ Found in Text Mining only
Myeloid Leukemia	Myeloid Leukemia	BEFREE	30635626		★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	30003933		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	21817013, 23071531, 24030748, 24086756, 24117486, 26490982, 28076379, 28270234, 28381186, 30301530, 30343319, 30697074		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	31511046		★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	Pubtator	31511046	Associate	★☆☆☆☆ Found in Text Mining only
oligodendroglioma	Oligodendroglioma	BEFREE	21817013, 22588899, 22869205, 22913971, 23373454, 24117486, 25694352, 25943885		★☆☆☆☆ Found in Text Mining only
Oligodendroglioma	Oligodendroglioma	Pubtator	21817013, 22869205, 23071531, 25694352, 26068201, 28388591	Associate	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	31651209	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	30301530		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	33649780	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	37910256	Inhibit	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	LHGDN	16672220		★☆☆☆☆ Found in Text Mining only
Primary malignant neoplasm of brain	Brain Neoplasms	BEFREE	22869205		★☆☆☆☆ Found in Text Mining only
Rett Syndrome	Rett Syndrome	BEFREE	12939425		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	LHGDN	19165527		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	26490982		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	32339054	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	27157613, 28667493		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	28667493, 34872893	Associate	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	33987449	Associate	★☆☆☆☆ Found in Text Mining only
Well Differentiated Oligodendroglioma	Oligodendroglioma	BEFREE	21817013, 22588899, 22869205, 22913971, 23373454, 24117486, 25694352, 25943885		★☆☆☆☆ Found in Text Mining only