Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	8870
Gene name	Immediate early response 3
Gene symbol	IER3
Synonyms (NCBI Gene)	DIF-2DIF2GLY96IEX-1IEX-1LIEX1PRG1
Chromosome	6
Chromosome location	6p21.33
Summary	This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not g

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004200	hsa-miR-197-3p	Microarray	16822819
MIRT027607	hsa-miR-98-5p	Microarray	19088304
MIRT722053	hsa-miR-499b-5p	HITS-CLIP	19536157
MIRT722052	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT722050	hsa-miR-7977	HITS-CLIP	19536157
MIRT512839	hsa-miR-3942-5p	PAR-CLIP	23446348
MIRT512838	hsa-miR-4703-5p	PAR-CLIP	23446348
MIRT512837	hsa-miR-28-5p	PAR-CLIP	23446348
MIRT512836	hsa-miR-3139	PAR-CLIP	23446348
MIRT512835	hsa-miR-708-5p	PAR-CLIP	23446348
MIRT512834	hsa-miR-4266	PAR-CLIP	23446348
MIRT440468	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT440469	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440468	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT727473	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727472	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727471	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727470	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT440469	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT727469	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT727468	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT722053	hsa-miR-499b-5p	PAR-CLIP	26701625
MIRT722053	hsa-miR-499b-5p	PAR-CLIP	26701625
MIRT722053	hsa-miR-499b-5p	PAR-CLIP	26701625
MIRT722053	hsa-miR-499b-5p	HITS-CLIP	19536157
MIRT722052	hsa-miR-6729-3p	HITS-CLIP	19536157
MIRT722050	hsa-miR-7977	HITS-CLIP	19536157
MIRT512839	hsa-miR-3942-5p	PAR-CLIP	23446348
MIRT512838	hsa-miR-4703-5p	PAR-CLIP	23446348
MIRT512837	hsa-miR-28-5p	PAR-CLIP	23446348
MIRT512836	hsa-miR-3139	PAR-CLIP	23446348
MIRT512835	hsa-miR-708-5p	PAR-CLIP	23446348
MIRT512834	hsa-miR-4266	PAR-CLIP	23446348
MIRT1059804	hsa-miR-1207-3p	CLIP-seq
MIRT1059805	hsa-miR-1228	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT1059807	hsa-miR-1273g	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059809	hsa-miR-1297	CLIP-seq
MIRT1059810	hsa-miR-1324	CLIP-seq
MIRT1059811	hsa-miR-136	CLIP-seq
MIRT1059812	hsa-miR-142-3p	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059814	hsa-miR-153	CLIP-seq
MIRT1059815	hsa-miR-1587	CLIP-seq
MIRT1059816	hsa-miR-188-3p	CLIP-seq
MIRT1059817	hsa-miR-1909	CLIP-seq
MIRT1059818	hsa-miR-2110	CLIP-seq
MIRT1059819	hsa-miR-2115	CLIP-seq
MIRT1059820	hsa-miR-214	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059823	hsa-miR-26a	CLIP-seq
MIRT1059824	hsa-miR-26b	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059827	hsa-miR-3120-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT1059829	hsa-miR-3150a-3p	CLIP-seq
MIRT1059830	hsa-miR-3152-5p	CLIP-seq
MIRT1059831	hsa-miR-3166	CLIP-seq
MIRT1059832	hsa-miR-3175	CLIP-seq
MIRT1059833	hsa-miR-342-3p	CLIP-seq
MIRT1059834	hsa-miR-3605-3p	CLIP-seq
MIRT1059835	hsa-miR-3619-5p	CLIP-seq
MIRT1059836	hsa-miR-370	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059838	hsa-miR-378g	CLIP-seq
MIRT1059839	hsa-miR-3934	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059841	hsa-miR-4255	CLIP-seq
MIRT1059842	hsa-miR-4258	CLIP-seq
MIRT1059843	hsa-miR-4259	CLIP-seq
MIRT1059844	hsa-miR-4260	CLIP-seq
MIRT1059845	hsa-miR-4281	CLIP-seq
MIRT1059846	hsa-miR-4303	CLIP-seq
MIRT1059847	hsa-miR-4320	CLIP-seq
MIRT1059848	hsa-miR-4323	CLIP-seq
MIRT1059849	hsa-miR-4423-5p	CLIP-seq
MIRT1059850	hsa-miR-4450	CLIP-seq
MIRT1059851	hsa-miR-4465	CLIP-seq
MIRT1059852	hsa-miR-448	CLIP-seq
MIRT1059853	hsa-miR-4484	CLIP-seq
MIRT1059854	hsa-miR-4492	CLIP-seq
MIRT1059855	hsa-miR-4498	CLIP-seq
MIRT1059856	hsa-miR-4509	CLIP-seq
MIRT1059857	hsa-miR-4645-3p	CLIP-seq
MIRT1059858	hsa-miR-4656	CLIP-seq
MIRT1059859	hsa-miR-4675	CLIP-seq
MIRT1059860	hsa-miR-4682	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059862	hsa-miR-4691-3p	CLIP-seq
MIRT1059863	hsa-miR-4694-5p	CLIP-seq
MIRT1059864	hsa-miR-4695-3p	CLIP-seq
MIRT1059865	hsa-miR-4695-5p	CLIP-seq
MIRT1059866	hsa-miR-4706	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059868	hsa-miR-4716-3p	CLIP-seq
MIRT1059869	hsa-miR-4733-3p	CLIP-seq
MIRT1059870	hsa-miR-4741	CLIP-seq
MIRT1059871	hsa-miR-4746-5p	CLIP-seq
MIRT1059872	hsa-miR-4749-5p	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059874	hsa-miR-4771	CLIP-seq
MIRT1059875	hsa-miR-4779	CLIP-seq
MIRT1059876	hsa-miR-4787-3p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059878	hsa-miR-516a-3p	CLIP-seq
MIRT1059879	hsa-miR-542-3p	CLIP-seq
MIRT1059880	hsa-miR-548an	CLIP-seq
MIRT1059881	hsa-miR-550a	CLIP-seq
MIRT1059882	hsa-miR-574-3p	CLIP-seq
MIRT1059883	hsa-miR-590-3p	CLIP-seq
MIRT1059884	hsa-miR-593	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059886	hsa-miR-625	CLIP-seq
MIRT1059887	hsa-miR-708	CLIP-seq
MIRT1059888	hsa-miR-744	CLIP-seq
MIRT1059889	hsa-miR-761	CLIP-seq
MIRT1059890	hsa-miR-762	CLIP-seq
MIRT1059891	hsa-miR-769-5p	CLIP-seq
MIRT1059892	hsa-miR-933	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059894	hsa-miR-939	CLIP-seq
MIRT1059807	hsa-miR-1273g	CLIP-seq
MIRT1059818	hsa-miR-2110	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059829	hsa-miR-3150a-3p	CLIP-seq
MIRT1059832	hsa-miR-3175	CLIP-seq
MIRT1059833	hsa-miR-342-3p	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059844	hsa-miR-4260	CLIP-seq
MIRT1059847	hsa-miR-4320	CLIP-seq
MIRT1059866	hsa-miR-4706	CLIP-seq
MIRT1059872	hsa-miR-4749-5p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059888	hsa-miR-744	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059894	hsa-miR-939	CLIP-seq
MIRT1059804	hsa-miR-1207-3p	CLIP-seq
MIRT2013936	hsa-miR-1224-3p	CLIP-seq
MIRT1059805	hsa-miR-1228	CLIP-seq
MIRT2013937	hsa-miR-1260	CLIP-seq
MIRT2013938	hsa-miR-1260b	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT1059807	hsa-miR-1273g	CLIP-seq
MIRT2013939	hsa-miR-1280	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059809	hsa-miR-1297	CLIP-seq
MIRT1059810	hsa-miR-1324	CLIP-seq
MIRT1059811	hsa-miR-136	CLIP-seq
MIRT1059812	hsa-miR-142-3p	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059814	hsa-miR-153	CLIP-seq
MIRT1059815	hsa-miR-1587	CLIP-seq
MIRT1059816	hsa-miR-188-3p	CLIP-seq
MIRT1059817	hsa-miR-1909	CLIP-seq
MIRT1059818	hsa-miR-2110	CLIP-seq
MIRT1059819	hsa-miR-2115	CLIP-seq
MIRT1059820	hsa-miR-214	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059823	hsa-miR-26a	CLIP-seq
MIRT1059824	hsa-miR-26b	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059827	hsa-miR-3120-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT1059829	hsa-miR-3150a-3p	CLIP-seq
MIRT1059830	hsa-miR-3152-5p	CLIP-seq
MIRT2013940	hsa-miR-3156-3p	CLIP-seq
MIRT1059831	hsa-miR-3166	CLIP-seq
MIRT1059832	hsa-miR-3175	CLIP-seq
MIRT2013941	hsa-miR-3202	CLIP-seq
MIRT1059833	hsa-miR-342-3p	CLIP-seq
MIRT1059834	hsa-miR-3605-3p	CLIP-seq
MIRT2013942	hsa-miR-361-3p	CLIP-seq
MIRT1059835	hsa-miR-3619-5p	CLIP-seq
MIRT2013943	hsa-miR-3667-3p	CLIP-seq
MIRT1059836	hsa-miR-370	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059838	hsa-miR-378g	CLIP-seq
MIRT1059839	hsa-miR-3934	CLIP-seq
MIRT2013944	hsa-miR-3943	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059841	hsa-miR-4255	CLIP-seq
MIRT1059843	hsa-miR-4259	CLIP-seq
MIRT1059844	hsa-miR-4260	CLIP-seq
MIRT1059846	hsa-miR-4303	CLIP-seq
MIRT1059847	hsa-miR-4320	CLIP-seq
MIRT1059848	hsa-miR-4323	CLIP-seq
MIRT1059849	hsa-miR-4423-5p	CLIP-seq
MIRT2013945	hsa-miR-4426	CLIP-seq
MIRT1059850	hsa-miR-4450	CLIP-seq
MIRT1059851	hsa-miR-4465	CLIP-seq
MIRT1059852	hsa-miR-448	CLIP-seq
MIRT1059853	hsa-miR-4484	CLIP-seq
MIRT1059854	hsa-miR-4492	CLIP-seq
MIRT1059855	hsa-miR-4498	CLIP-seq
MIRT1059856	hsa-miR-4509	CLIP-seq
MIRT2013946	hsa-miR-4533	CLIP-seq
MIRT2013947	hsa-miR-4643	CLIP-seq
MIRT1059857	hsa-miR-4645-3p	CLIP-seq
MIRT2013948	hsa-miR-4647	CLIP-seq
MIRT1059858	hsa-miR-4656	CLIP-seq
MIRT2013949	hsa-miR-4659a-3p	CLIP-seq
MIRT2013950	hsa-miR-4659b-3p	CLIP-seq
MIRT2013951	hsa-miR-466	CLIP-seq
MIRT2013952	hsa-miR-4662b	CLIP-seq
MIRT1059859	hsa-miR-4675	CLIP-seq
MIRT1059860	hsa-miR-4682	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059862	hsa-miR-4691-3p	CLIP-seq
MIRT1059863	hsa-miR-4694-5p	CLIP-seq
MIRT1059864	hsa-miR-4695-3p	CLIP-seq
MIRT1059865	hsa-miR-4695-5p	CLIP-seq
MIRT1059866	hsa-miR-4706	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059868	hsa-miR-4716-3p	CLIP-seq
MIRT1059869	hsa-miR-4733-3p	CLIP-seq
MIRT1059870	hsa-miR-4741	CLIP-seq
MIRT1059872	hsa-miR-4749-5p	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059874	hsa-miR-4771	CLIP-seq
MIRT1059875	hsa-miR-4779	CLIP-seq
MIRT2013953	hsa-miR-4789-3p	CLIP-seq
MIRT2013954	hsa-miR-499a-5p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059878	hsa-miR-516a-3p	CLIP-seq
MIRT1059879	hsa-miR-542-3p	CLIP-seq
MIRT1059880	hsa-miR-548an	CLIP-seq
MIRT1059881	hsa-miR-550a	CLIP-seq
MIRT2013955	hsa-miR-551b	CLIP-seq
MIRT1059882	hsa-miR-574-3p	CLIP-seq
MIRT1059883	hsa-miR-590-3p	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059886	hsa-miR-625	CLIP-seq
MIRT1059887	hsa-miR-708	CLIP-seq
MIRT1059888	hsa-miR-744	CLIP-seq
MIRT1059889	hsa-miR-761	CLIP-seq
MIRT1059890	hsa-miR-762	CLIP-seq
MIRT1059891	hsa-miR-769-5p	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059894	hsa-miR-939	CLIP-seq
MIRT2013956	hsa-miR-942	CLIP-seq
MIRT1059804	hsa-miR-1207-3p	CLIP-seq
MIRT2013936	hsa-miR-1224-3p	CLIP-seq
MIRT1059805	hsa-miR-1228	CLIP-seq
MIRT2013937	hsa-miR-1260	CLIP-seq
MIRT2013938	hsa-miR-1260b	CLIP-seq
MIRT2013939	hsa-miR-1280	CLIP-seq
MIRT1059809	hsa-miR-1297	CLIP-seq
MIRT1059811	hsa-miR-136	CLIP-seq
MIRT1059812	hsa-miR-142-3p	CLIP-seq
MIRT1059814	hsa-miR-153	CLIP-seq
MIRT1059815	hsa-miR-1587	CLIP-seq
MIRT1059816	hsa-miR-188-3p	CLIP-seq
MIRT1059818	hsa-miR-2110	CLIP-seq
MIRT1059819	hsa-miR-2115	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059823	hsa-miR-26a	CLIP-seq
MIRT1059824	hsa-miR-26b	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059829	hsa-miR-3150a-3p	CLIP-seq
MIRT2013940	hsa-miR-3156-3p	CLIP-seq
MIRT1059832	hsa-miR-3175	CLIP-seq
MIRT1059833	hsa-miR-342-3p	CLIP-seq
MIRT2013943	hsa-miR-3667-3p	CLIP-seq
MIRT1059836	hsa-miR-370	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059838	hsa-miR-378g	CLIP-seq
MIRT1059839	hsa-miR-3934	CLIP-seq
MIRT2013944	hsa-miR-3943	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059841	hsa-miR-4255	CLIP-seq
MIRT1059842	hsa-miR-4258	CLIP-seq
MIRT1059844	hsa-miR-4260	CLIP-seq
MIRT1059845	hsa-miR-4281	CLIP-seq
MIRT1059847	hsa-miR-4320	CLIP-seq
MIRT1059848	hsa-miR-4323	CLIP-seq
MIRT1059851	hsa-miR-4465	CLIP-seq
MIRT1059852	hsa-miR-448	CLIP-seq
MIRT1059853	hsa-miR-4484	CLIP-seq
MIRT1059854	hsa-miR-4492	CLIP-seq
MIRT1059855	hsa-miR-4498	CLIP-seq
MIRT1059856	hsa-miR-4509	CLIP-seq
MIRT2013947	hsa-miR-4643	CLIP-seq
MIRT1059858	hsa-miR-4656	CLIP-seq
MIRT2013951	hsa-miR-466	CLIP-seq
MIRT1059859	hsa-miR-4675	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059862	hsa-miR-4691-3p	CLIP-seq
MIRT1059869	hsa-miR-4733-3p	CLIP-seq
MIRT1059870	hsa-miR-4741	CLIP-seq
MIRT1059871	hsa-miR-4746-5p	CLIP-seq
MIRT1059876	hsa-miR-4787-3p	CLIP-seq
MIRT2013953	hsa-miR-4789-3p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059878	hsa-miR-516a-3p	CLIP-seq
MIRT1059880	hsa-miR-548an	CLIP-seq
MIRT1059881	hsa-miR-550a	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059890	hsa-miR-762	CLIP-seq
MIRT1059892	hsa-miR-933	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059894	hsa-miR-939	CLIP-seq
MIRT1059804	hsa-miR-1207-3p	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059815	hsa-miR-1587	CLIP-seq
MIRT1059816	hsa-miR-188-3p	CLIP-seq
MIRT1059817	hsa-miR-1909	CLIP-seq
MIRT1059820	hsa-miR-214	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059827	hsa-miR-3120-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT2013942	hsa-miR-361-3p	CLIP-seq
MIRT1059835	hsa-miR-3619-5p	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059838	hsa-miR-378g	CLIP-seq
MIRT2013944	hsa-miR-3943	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059848	hsa-miR-4323	CLIP-seq
MIRT1059854	hsa-miR-4492	CLIP-seq
MIRT1059855	hsa-miR-4498	CLIP-seq
MIRT1059858	hsa-miR-4656	CLIP-seq
MIRT2013949	hsa-miR-4659a-3p	CLIP-seq
MIRT2013950	hsa-miR-4659b-3p	CLIP-seq
MIRT1059859	hsa-miR-4675	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059868	hsa-miR-4716-3p	CLIP-seq
MIRT1059870	hsa-miR-4741	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059876	hsa-miR-4787-3p	CLIP-seq
MIRT2013954	hsa-miR-499a-5p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059881	hsa-miR-550a	CLIP-seq
MIRT2013955	hsa-miR-551b	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059886	hsa-miR-625	CLIP-seq
MIRT1059889	hsa-miR-761	CLIP-seq
MIRT1059890	hsa-miR-762	CLIP-seq
MIRT1059891	hsa-miR-769-5p	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059825	hsa-miR-27a	CLIP-seq
MIRT1059826	hsa-miR-27b	CLIP-seq
MIRT1059857	hsa-miR-4645-3p	CLIP-seq
MIRT1059877	hsa-miR-513a-5p	CLIP-seq
MIRT1059883	hsa-miR-590-3p	CLIP-seq
MIRT1059885	hsa-miR-599	CLIP-seq
MIRT1059804	hsa-miR-1207-3p	CLIP-seq
MIRT2013936	hsa-miR-1224-3p	CLIP-seq
MIRT2013937	hsa-miR-1260	CLIP-seq
MIRT2013938	hsa-miR-1260b	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT2013939	hsa-miR-1280	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059815	hsa-miR-1587	CLIP-seq
MIRT1059816	hsa-miR-188-3p	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT2013940	hsa-miR-3156-3p	CLIP-seq
MIRT2013941	hsa-miR-3202	CLIP-seq
MIRT1059833	hsa-miR-342-3p	CLIP-seq
MIRT1059834	hsa-miR-3605-3p	CLIP-seq
MIRT2013943	hsa-miR-3667-3p	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059838	hsa-miR-378g	CLIP-seq
MIRT2013944	hsa-miR-3943	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059848	hsa-miR-4323	CLIP-seq
MIRT2013945	hsa-miR-4426	CLIP-seq
MIRT1059853	hsa-miR-4484	CLIP-seq
MIRT1059854	hsa-miR-4492	CLIP-seq
MIRT1059855	hsa-miR-4498	CLIP-seq
MIRT1059856	hsa-miR-4509	CLIP-seq
MIRT2013946	hsa-miR-4533	CLIP-seq
MIRT2013947	hsa-miR-4643	CLIP-seq
MIRT2013948	hsa-miR-4647	CLIP-seq
MIRT1059858	hsa-miR-4656	CLIP-seq
MIRT2013951	hsa-miR-466	CLIP-seq
MIRT2013952	hsa-miR-4662b	CLIP-seq
MIRT1059859	hsa-miR-4675	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059862	hsa-miR-4691-3p	CLIP-seq
MIRT1059864	hsa-miR-4695-3p	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059870	hsa-miR-4741	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059876	hsa-miR-4787-3p	CLIP-seq
MIRT2013953	hsa-miR-4789-3p	CLIP-seq
MIRT1059879	hsa-miR-542-3p	CLIP-seq
MIRT1059880	hsa-miR-548an	CLIP-seq
MIRT1059881	hsa-miR-550a	CLIP-seq
MIRT1059890	hsa-miR-762	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059805	hsa-miR-1228	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059811	hsa-miR-136	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059814	hsa-miR-153	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059852	hsa-miR-448	CLIP-seq
MIRT2013947	hsa-miR-4643	CLIP-seq
MIRT2013951	hsa-miR-466	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059862	hsa-miR-4691-3p	CLIP-seq
MIRT1059865	hsa-miR-4695-5p	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059875	hsa-miR-4779	CLIP-seq
MIRT2013953	hsa-miR-4789-3p	CLIP-seq
MIRT1059887	hsa-miR-708	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq
MIRT1059805	hsa-miR-1228	CLIP-seq
MIRT1059806	hsa-miR-1273f	CLIP-seq
MIRT1059808	hsa-miR-1287	CLIP-seq
MIRT1059811	hsa-miR-136	CLIP-seq
MIRT1059813	hsa-miR-143	CLIP-seq
MIRT1059814	hsa-miR-153	CLIP-seq
MIRT1059821	hsa-miR-219-1-3p	CLIP-seq
MIRT1059822	hsa-miR-2277-3p	CLIP-seq
MIRT1059828	hsa-miR-3135b	CLIP-seq
MIRT1059837	hsa-miR-377	CLIP-seq
MIRT1059840	hsa-miR-411	CLIP-seq
MIRT1059852	hsa-miR-448	CLIP-seq
MIRT2013947	hsa-miR-4643	CLIP-seq
MIRT2013951	hsa-miR-466	CLIP-seq
MIRT1059861	hsa-miR-4690-3p	CLIP-seq
MIRT1059865	hsa-miR-4695-5p	CLIP-seq
MIRT1059867	hsa-miR-4708-5p	CLIP-seq
MIRT1059873	hsa-miR-4770	CLIP-seq
MIRT1059875	hsa-miR-4779	CLIP-seq
MIRT2013953	hsa-miR-4789-3p	CLIP-seq
MIRT1059893	hsa-miR-936	CLIP-seq

Show/Hide all (6)

Transcription factor	Regulation	Reference
HOXA1	Unknown	17213808
MYC	Unknown	12360408
NFKB1	Unknown	12360408
REL	Unknown	12360408
RELA	Unknown	12360408
TP53	Unknown	12360408

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001562	Process	Response to protozoan	IEA
GO:0003085	Process	Negative regulation of systemic arterial blood pressure	IEA
GO:0005515	Function	Protein binding	IPI	15451437, 16456541, 18191642, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	20467439
GO:0005634	Component	Nucleus	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006096	Process	Glycolytic process	IEA
GO:0006282	Process	Regulation of DNA repair	IEA
GO:0006915	Process	Apoptotic process	TAS	9196025
GO:0006974	Process	DNA damage response	IBA
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	IMP	20467439
GO:0007095	Process	Mitotic G2 DNA damage checkpoint signaling	IEA
GO:0008630	Process	Intrinsic apoptotic signaling pathway in response to DNA damage	IEA
GO:0009653	Process	Anatomical structure morphogenesis	TAS	9196025
GO:0016020	Component	Membrane	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	TAS	9703517
GO:0045732	Process	Positive regulation of protein catabolic process	IEA
GO:0045820	Process	Negative regulation of glycolytic process	IEA
GO:0046822	Process	Regulation of nucleocytoplasmic transport	IEA
GO:0050728	Process	Negative regulation of inflammatory response	IEA
GO:1901029	Process	Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	IEA
GO:2000377	Process	Regulation of reactive oxygen species metabolic process	IEA

MIM	HGNC	e!Ensembl
602996	5392	ENSG00000137331

P46695

Protein name

Radiation-inducible immediate-early gene IEX-1 (Differentiation-dependent gene 2 protein) (Protein DIF-2) (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1)

Protein function

May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Also acts as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may

Family and domains

Sequence

MCHSRSCHPTMTILQAPTPAPSTIPGPRRGSGPEIFTFDPLPEPAAAPAGRPSASRGHRK
RSRRVLYPRVVRRQLPVEEPNPAKRLLFLLLTIVFCQILMAEEGVPAPLPPEDAPNAASL
APTPVSAVLEPFNLTSEPSDYALDLSTFLQQHPAAF

Sequence length

156

Interactions

View interactions

	Reactome
			PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DERMATITIS, IRRITANT	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DERMATOLOGIC DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSIVE DISEASE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SKIN DISEASES	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SKIN DISEASES, GENETIC	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (79)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acute Promyelocytic Leukemia	Promyelocytic Leukemia	BEFREE	15306824		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	26986830		★★★★★ ★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	25250570		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arsenic Encephalopathy	Arsenic Encephalopathy	CTD_human_DG	16835338		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	27736946, 27898717	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	BEFREE	11782530		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autoimmune Diseases	Autoimmune Diseases	LHGDN	11782530		★★★★★ ★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	30249226		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	23534784, 25684507, 26986830, 27736946	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	27336713, 35291486, 37354485	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	30249226		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Ovarian Epithelial	Epithelial ovarian carcinoma	Pubtator	29431239	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	29431239		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomegaly	Cardiomegaly	Pubtator	15451437	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Cardiomyopathy, Dilated	Cardiomyopathy	BEFREE	28353642		★★★★★ ★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	25666857, 30579899		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	25666857, 26973248, 30579899		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	24311782		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	23379921		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	21335489		★★★★★ ★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn disease	Pubtator	38001042	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	27736946		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis, Irritant	Dermatitis	CTD_human_DG	27258892		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Dermatologic disorders	Dermatologic Disorders	CTD_human_DG	16835338		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Endometriosis	Endometriosis	BEFREE	31636893		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	18564103		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	18564103		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	LHGDN	16960879		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	18564103		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Iga nephropathy	Pubtator	36709307	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatitis C Chronic	Hepatitis c	Pubtator	24130824	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington Disease	BEFREE	17724341		★★★★★ ★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington disease	Pubtator	17724341	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperplasia	Hyperplasia	Pubtator	15451437	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	CTD_human_DG	20713914		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	BEFREE	21112119		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
leukemia	Leukemia	LHGDN	15855159		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	19773435		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	34729939	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Promyelocytic Acute	Promyelocytic leukemia	Pubtator	18039708	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	25684507, 27336713		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Diseases	Lung disease	Pubtator	30343628	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	23534784, 37442331	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	26986830		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus	Lupus Erythematosus	BEFREE	11782530		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Discoid	Lupus Erythematosus	BEFREE	11782530		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	11782530, 12371964		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Vulgaris	Lupus Vulgaris	BEFREE	11782530		★★★★★ ★☆☆☆☆ Found in Text Mining only
Macular Degeneration	Macular degeneration	Pubtator	34061866	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	23508637		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	25250570		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of tongue	Malignant Neoplasm Of Tongue	BEFREE	31832020		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	30249226		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	15087407, 21052099, 21112119, 23320102, 23379921, 30249226		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	25666857, 30579899		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental disorders	Mental Disorders	BEFREE	26671989, 28843862		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Multiple myeloma	Pubtator	19690192	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	19773435, 20592488, 22875062		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	12411319	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	23320102	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Infarction	Myocardial Infarction	BEFREE	29213350		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	17704804, 19773435, 21052099, 23379921, 24311782, 25666857, 25684507, 30249226, 9101411		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	19920113		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Cysts	Ovarian cysts	Pubtator	39377902	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	29431239	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	25250570		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	LHGDN	18026799		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatitis	Pancreatitis	BEFREE	25250570		★★★★★ ★☆☆☆☆ Found in Text Mining only
Peritonitis	Peritonitis	Pubtator	25684507	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	37279148	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pseudohyperkalemia Cardiff	Pseudohyperkalemia Cardiff	BEFREE	24130824		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	27736946		★★★★★ ★☆☆☆☆ Found in Text Mining only
Severe Combined Immunodeficiency	Severe combined immunodeficiency disease	BEFREE	17704804		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sezary Syndrome	Sezary Syndrome	BEFREE	22417305		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sezary Syndrome	Sezary syndrome	Pubtator	22417305	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tetralogy of Fallot	Tetralogy of fallot	Pubtator	30977211	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	30249226	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	25666857, 33228592	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	26973248	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only

IER3 (immediate early response 3)