DPM2 (dolichyl-phosphate mannosyltransferase subunit 2, regulatory)

Gene

• Entrez ID: 8818
• Gene name: Dolichyl-phosphate mannosyltransferase subunit 2, regulatory
• Gene symbol: DPM2
• Synonyms (NCBI Gene): CDG1U
• Chromosome: 9
• Chromosome location: 9q34.11
• Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mann

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs397514503	T>C	Pathogenic	Intron variant, non coding transcript variant, missense variant, coding sequence variant
rs797044467	C>G,T	Pathogenic	Intron variant, splice acceptor variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT477982	hsa-miR-634	PAR-CLIP	23592263
MIRT477981	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT477980	hsa-miR-4779	PAR-CLIP	23592263
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT477976	hsa-miR-4501	PAR-CLIP	23592263
MIRT477975	hsa-miR-4459	PAR-CLIP	23592263
MIRT477974	hsa-miR-4270	PAR-CLIP	23592263
MIRT477973	hsa-miR-4441	PAR-CLIP	23592263
MIRT477972	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT477969	hsa-miR-4251	PAR-CLIP	23592263
MIRT477968	hsa-miR-4329	PAR-CLIP	23592263
MIRT477967	hsa-miR-6761-5p	PAR-CLIP	23592263
MIRT477966	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT477965	hsa-miR-4751	PAR-CLIP	23592263
MIRT477964	hsa-miR-1827	PAR-CLIP	23592263
MIRT477963	hsa-miR-655-5p	PAR-CLIP	23592263
MIRT477962	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT477961	hsa-miR-6086	PAR-CLIP	23592263
MIRT477960	hsa-miR-4696	PAR-CLIP	23592263
MIRT477959	hsa-miR-6124	PAR-CLIP	23592263
MIRT477958	hsa-miR-4294	PAR-CLIP	23592263
MIRT477957	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT477954	hsa-miR-4736	PAR-CLIP	23592263
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477952	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT477951	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT477947	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT477946	hsa-miR-4271	PAR-CLIP	23592263
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT477943	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT477942	hsa-miR-4504	PAR-CLIP	23592263
MIRT477941	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT477940	hsa-miR-4316	PAR-CLIP	23592263
MIRT477939	hsa-miR-1294	PAR-CLIP	23592263
MIRT477938	hsa-miR-4425	PAR-CLIP	23592263
MIRT477937	hsa-miR-7150	PAR-CLIP	23592263
MIRT477936	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT477935	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT477934	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477933	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT477932	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT477931	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT477930	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT477929	hsa-miR-3689c	PAR-CLIP	23592263
MIRT477928	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT477927	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT477926	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT440779	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440779	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	26701625
MIRT477951	hsa-miR-149-3p	PAR-CLIP	26701625
MIRT477964	hsa-miR-1827	PAR-CLIP	26701625
MIRT477964	hsa-miR-1827	PAR-CLIP	26701625
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	26701625
MIRT477957	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT477957	hsa-miR-31-5p	PAR-CLIP	26701625
MIRT477946	hsa-miR-4271	PAR-CLIP	26701625
MIRT477946	hsa-miR-4271	PAR-CLIP	26701625
MIRT477940	hsa-miR-4316	PAR-CLIP	26701625
MIRT477940	hsa-miR-4316	PAR-CLIP	26701625
MIRT477975	hsa-miR-4459	PAR-CLIP	26701625
MIRT477975	hsa-miR-4459	PAR-CLIP	26701625
MIRT477976	hsa-miR-4501	PAR-CLIP	26701625
MIRT477976	hsa-miR-4501	PAR-CLIP	26701625
MIRT477942	hsa-miR-4504	PAR-CLIP	26701625
MIRT477942	hsa-miR-4504	PAR-CLIP	26701625
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	26701625
MIRT477960	hsa-miR-4696	PAR-CLIP	26701625
MIRT477960	hsa-miR-4696	PAR-CLIP	26701625
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	26701625
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	26701625
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	26701625
MIRT477954	hsa-miR-4736	PAR-CLIP	26701625
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	26701625
MIRT477980	hsa-miR-4779	PAR-CLIP	26701625
MIRT477980	hsa-miR-4779	PAR-CLIP	26701625
MIRT477941	hsa-miR-542-3p	PAR-CLIP	26701625
MIRT477941	hsa-miR-542-3p	PAR-CLIP	26701625
MIRT477959	hsa-miR-6124	PAR-CLIP	26701625
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	26701625
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	26701625
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	26701625
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	26701625
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	26701625
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	26701625
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	26701625
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	26701625
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	26701625
MIRT477937	hsa-miR-7150	PAR-CLIP	26701625
MIRT477982	hsa-miR-634	PAR-CLIP	23592263
MIRT477981	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT477980	hsa-miR-4779	PAR-CLIP	23592263
MIRT477979	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT477978	hsa-miR-6815-5p	PAR-CLIP	23592263
MIRT477977	hsa-miR-6865-5p	PAR-CLIP	23592263
MIRT477976	hsa-miR-4501	PAR-CLIP	23592263
MIRT477975	hsa-miR-4459	PAR-CLIP	23592263
MIRT477974	hsa-miR-4270	PAR-CLIP	23592263
MIRT477973	hsa-miR-4441	PAR-CLIP	23592263
MIRT477972	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT477971	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT477970	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT477969	hsa-miR-4251	PAR-CLIP	23592263
MIRT477968	hsa-miR-4329	PAR-CLIP	23592263
MIRT477967	hsa-miR-6761-5p	PAR-CLIP	23592263
MIRT477966	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT477965	hsa-miR-4751	PAR-CLIP	23592263
MIRT477964	hsa-miR-1827	PAR-CLIP	23592263
MIRT477963	hsa-miR-655-5p	PAR-CLIP	23592263
MIRT477962	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT477961	hsa-miR-6086	PAR-CLIP	23592263
MIRT477960	hsa-miR-4696	PAR-CLIP	23592263
MIRT477959	hsa-miR-6124	PAR-CLIP	23592263
MIRT477958	hsa-miR-4294	PAR-CLIP	23592263
MIRT477957	hsa-miR-31-5p	PAR-CLIP	23592263
MIRT477956	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT477955	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT477954	hsa-miR-4736	PAR-CLIP	23592263
MIRT477953	hsa-miR-4668-5p	PAR-CLIP	23592263
MIRT477952	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT477951	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT477950	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT477949	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT477948	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT477947	hsa-miR-6799-5p	PAR-CLIP	23592263
MIRT477946	hsa-miR-4271	PAR-CLIP	23592263
MIRT477945	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT477944	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT477943	hsa-miR-92a-1-5p	PAR-CLIP	23592263
MIRT477942	hsa-miR-4504	PAR-CLIP	23592263
MIRT477941	hsa-miR-542-3p	PAR-CLIP	23592263
MIRT477940	hsa-miR-4316	PAR-CLIP	23592263
MIRT477939	hsa-miR-1294	PAR-CLIP	23592263
MIRT477938	hsa-miR-4425	PAR-CLIP	23592263
MIRT477937	hsa-miR-7150	PAR-CLIP	23592263
MIRT477936	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT477935	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT477934	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT477933	hsa-miR-1273h-5p	PAR-CLIP	23592263
MIRT477932	hsa-miR-30b-3p	PAR-CLIP	23592263
MIRT477931	hsa-miR-3689a-3p	PAR-CLIP	23592263
MIRT477930	hsa-miR-3689b-3p	PAR-CLIP	23592263
MIRT477929	hsa-miR-3689c	PAR-CLIP	23592263
MIRT477928	hsa-miR-6779-5p	PAR-CLIP	23592263
MIRT477927	hsa-miR-6780a-5p	PAR-CLIP	23592263
MIRT477926	hsa-miR-887-5p	PAR-CLIP	23592263
MIRT944052	hsa-miR-1207-3p	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT944055	hsa-miR-125a-5p	CLIP-seq
MIRT944056	hsa-miR-125b	CLIP-seq
MIRT944057	hsa-miR-1287	CLIP-seq
MIRT944058	hsa-miR-1291	CLIP-seq
MIRT944059	hsa-miR-1295	CLIP-seq
MIRT944060	hsa-miR-1538	CLIP-seq
MIRT944061	hsa-miR-1914	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT944063	hsa-miR-198	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT944067	hsa-miR-3135b	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT944069	hsa-miR-3151	CLIP-seq
MIRT944070	hsa-miR-3154	CLIP-seq
MIRT944071	hsa-miR-3179	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT944073	hsa-miR-3194-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944078	hsa-miR-338-3p	CLIP-seq
MIRT944079	hsa-miR-339-5p	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT944082	hsa-miR-3649	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944089	hsa-miR-4265	CLIP-seq
MIRT944090	hsa-miR-4292	CLIP-seq
MIRT944091	hsa-miR-4296	CLIP-seq
MIRT944092	hsa-miR-4310	CLIP-seq
MIRT944093	hsa-miR-4319	CLIP-seq
MIRT944094	hsa-miR-4322	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT944096	hsa-miR-4447	CLIP-seq
MIRT944097	hsa-miR-4472	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT944102	hsa-miR-4532	CLIP-seq
MIRT944103	hsa-miR-4638-3p	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944105	hsa-miR-4640-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT944107	hsa-miR-4651	CLIP-seq
MIRT944108	hsa-miR-4667-5p	CLIP-seq
MIRT944109	hsa-miR-4675	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT944111	hsa-miR-4700-5p	CLIP-seq
MIRT944112	hsa-miR-4726-5p	CLIP-seq
MIRT944113	hsa-miR-4734	CLIP-seq
MIRT944114	hsa-miR-4741	CLIP-seq
MIRT944115	hsa-miR-4745-3p	CLIP-seq
MIRT944116	hsa-miR-4747-3p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT944118	hsa-miR-491-5p	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944120	hsa-miR-555	CLIP-seq
MIRT944121	hsa-miR-592	CLIP-seq
MIRT944122	hsa-miR-597	CLIP-seq
MIRT944123	hsa-miR-608	CLIP-seq
MIRT944124	hsa-miR-615-5p	CLIP-seq
MIRT944125	hsa-miR-637	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944127	hsa-miR-663b	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT944129	hsa-miR-885-3p	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT1979548	hsa-miR-1184	CLIP-seq
MIRT1979549	hsa-miR-1205	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT944055	hsa-miR-125a-5p	CLIP-seq
MIRT944056	hsa-miR-125b	CLIP-seq
MIRT1979550	hsa-miR-1286	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT1979552	hsa-miR-3144-5p	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT944069	hsa-miR-3151	CLIP-seq
MIRT1979553	hsa-miR-3158-5p	CLIP-seq
MIRT1979554	hsa-miR-3165	CLIP-seq
MIRT1979555	hsa-miR-3191	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT1979556	hsa-miR-3934	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944089	hsa-miR-4265	CLIP-seq
MIRT944091	hsa-miR-4296	CLIP-seq
MIRT944092	hsa-miR-4310	CLIP-seq
MIRT1979557	hsa-miR-4312	CLIP-seq
MIRT944093	hsa-miR-4319	CLIP-seq
MIRT944094	hsa-miR-4322	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT1979558	hsa-miR-4436a	CLIP-seq
MIRT944096	hsa-miR-4447	CLIP-seq
MIRT944097	hsa-miR-4472	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT1979559	hsa-miR-4514	CLIP-seq
MIRT1979560	hsa-miR-4522	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT1979561	hsa-miR-4652-5p	CLIP-seq
MIRT944108	hsa-miR-4667-5p	CLIP-seq
MIRT944109	hsa-miR-4675	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT1979562	hsa-miR-4692	CLIP-seq
MIRT944111	hsa-miR-4700-5p	CLIP-seq
MIRT1979563	hsa-miR-4722-5p	CLIP-seq
MIRT944114	hsa-miR-4741	CLIP-seq
MIRT1979564	hsa-miR-4756-3p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT944118	hsa-miR-491-5p	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944121	hsa-miR-592	CLIP-seq
MIRT944122	hsa-miR-597	CLIP-seq
MIRT944124	hsa-miR-615-5p	CLIP-seq
MIRT944125	hsa-miR-637	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT1979565	hsa-miR-765	CLIP-seq
MIRT1979566	hsa-miR-940	CLIP-seq
MIRT1979548	hsa-miR-1184	CLIP-seq
MIRT1979549	hsa-miR-1205	CLIP-seq
MIRT944052	hsa-miR-1207-3p	CLIP-seq
MIRT944053	hsa-miR-1224-5p	CLIP-seq
MIRT944054	hsa-miR-1254	CLIP-seq
MIRT1979550	hsa-miR-1286	CLIP-seq
MIRT2214643	hsa-miR-1299	CLIP-seq
MIRT2214644	hsa-miR-1470	CLIP-seq
MIRT2214645	hsa-miR-188-5p	CLIP-seq
MIRT2214646	hsa-miR-1910	CLIP-seq
MIRT944062	hsa-miR-1915	CLIP-seq
MIRT944063	hsa-miR-198	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT2214647	hsa-miR-223	CLIP-seq
MIRT2214648	hsa-miR-2355-5p	CLIP-seq
MIRT944064	hsa-miR-2861	CLIP-seq
MIRT944065	hsa-miR-31	CLIP-seq
MIRT944066	hsa-miR-3116	CLIP-seq
MIRT1979552	hsa-miR-3144-5p	CLIP-seq
MIRT944068	hsa-miR-3150b-3p	CLIP-seq
MIRT1979553	hsa-miR-3158-5p	CLIP-seq
MIRT1979554	hsa-miR-3165	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT1979555	hsa-miR-3191	CLIP-seq
MIRT944073	hsa-miR-3194-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944080	hsa-miR-3605-3p	CLIP-seq
MIRT944081	hsa-miR-3607-5p	CLIP-seq
MIRT2214649	hsa-miR-3667-3p	CLIP-seq
MIRT944083	hsa-miR-3690	CLIP-seq
MIRT944084	hsa-miR-377	CLIP-seq
MIRT944085	hsa-miR-3915	CLIP-seq
MIRT944086	hsa-miR-3919	CLIP-seq
MIRT1979556	hsa-miR-3934	CLIP-seq
MIRT944087	hsa-miR-4252	CLIP-seq
MIRT944088	hsa-miR-4260	CLIP-seq
MIRT944090	hsa-miR-4292	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq
MIRT1979557	hsa-miR-4312	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT1979558	hsa-miR-4436a	CLIP-seq
MIRT2214651	hsa-miR-4469	CLIP-seq
MIRT944098	hsa-miR-4489	CLIP-seq
MIRT944099	hsa-miR-4492	CLIP-seq
MIRT944100	hsa-miR-4498	CLIP-seq
MIRT944101	hsa-miR-4505	CLIP-seq
MIRT1979559	hsa-miR-4514	CLIP-seq
MIRT2214652	hsa-miR-4520a-3p	CLIP-seq
MIRT1979560	hsa-miR-4522	CLIP-seq
MIRT2214653	hsa-miR-455-3p	CLIP-seq
MIRT944103	hsa-miR-4638-3p	CLIP-seq
MIRT944104	hsa-miR-4639-5p	CLIP-seq
MIRT944106	hsa-miR-4643	CLIP-seq
MIRT1979561	hsa-miR-4652-5p	CLIP-seq
MIRT2214654	hsa-miR-4667-3p	CLIP-seq
MIRT944110	hsa-miR-4689	CLIP-seq
MIRT1979562	hsa-miR-4692	CLIP-seq
MIRT2214655	hsa-miR-4697-3p	CLIP-seq
MIRT1979563	hsa-miR-4722-5p	CLIP-seq
MIRT1979564	hsa-miR-4756-3p	CLIP-seq
MIRT2214656	hsa-miR-4782-5p	CLIP-seq
MIRT944117	hsa-miR-4784	CLIP-seq
MIRT2214657	hsa-miR-4795-5p	CLIP-seq
MIRT2214658	hsa-miR-516b	CLIP-seq
MIRT944119	hsa-miR-550a	CLIP-seq
MIRT944126	hsa-miR-661	CLIP-seq
MIRT944127	hsa-miR-663b	CLIP-seq
MIRT944128	hsa-miR-762	CLIP-seq
MIRT1979565	hsa-miR-765	CLIP-seq
MIRT2214659	hsa-miR-875-3p	CLIP-seq
MIRT1979566	hsa-miR-940	CLIP-seq
MIRT1979551	hsa-miR-22	CLIP-seq
MIRT944072	hsa-miR-3180-5p	CLIP-seq
MIRT944074	hsa-miR-320a	CLIP-seq
MIRT944075	hsa-miR-320b	CLIP-seq
MIRT944076	hsa-miR-320c	CLIP-seq
MIRT944077	hsa-miR-320d	CLIP-seq
MIRT944095	hsa-miR-4429	CLIP-seq
MIRT2214643	hsa-miR-1299	CLIP-seq
MIRT2214659	hsa-miR-875-3p	CLIP-seq
MIRT2519054	hsa-miR-329	CLIP-seq
MIRT2519055	hsa-miR-362-3p	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq
MIRT2519054	hsa-miR-329	CLIP-seq
MIRT2519055	hsa-miR-362-3p	CLIP-seq
MIRT2214650	hsa-miR-4302	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	IDA	10944123, 16162815
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	IPI	16162815
GO:0000506	Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	TAS	16280320
GO:0005515	Function	Protein binding	IPI	10835346, 10944123, 16162815
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	16162815
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	NAS	9724629
GO:0005789	Component	Endoplasmic reticulum membrane	TAS	9724629, 16280320
GO:0006486	Process	Protein glycosylation	IEA
GO:0006488	Process	Dolichol-linked oligosaccharide biosynthetic process	IBA
GO:0006506	Process	GPI anchor biosynthetic process	IDA	16162815
GO:0008047	Function	Enzyme activator activity	IDA	10835346
GO:0016020	Component	Membrane	IEA
GO:0030234	Function	Enzyme regulator activity	IBA
GO:0030234	Function	Enzyme regulator activity	IEA
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IBA
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IDA	10835346
GO:0033185	Component	Dolichol-phosphate-mannose synthase complex	IPI	10835346
GO:0180047	Process	Dolichol phosphate mannose biosynthetic process	IDA	10835346
GO:0180047	Process	Dolichol phosphate mannose biosynthetic process	IEA

Other IDs

• MIM: 603564
• HGNC: 3006
• e!Ensembl: ENSG00000136908

Protein

• UniProt ID: O94777
• Protein name: Dolichol phosphate-mannose biosynthesis regulatory protein (Dolichol-phosphate mannose synthase subunit 2) (DPM synthase subunit 2)
• Protein function: Regulates the biosynthesis of dolichol phosphate-mannose (PubMed:10835346). Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1 (PubMed:10835346). Part of t
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07297	DPM2	5 → 81	Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)	Family

• Sequence:

  MATGTDQVVGLGLVAVSLIIFTYYTAWVILLPFIDSQHVIHKYFLPRAYAVAIPLAAGLL
  LLLFVGLFISYVMLKTKRVTKKAQ

• Sequence length: 84

Pathways

KEGG:

N-Glycan biosynthesis
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Metabolic pathways

Reactome:

Synthesis of dolichyl-phosphate mannose
Synthesis of glycosylphosphatidylinositol (GPI)
Defective DPM1 causes DPM1-CDG (CDG-1e)
Defective DPM3 causes DPM3-CDG (CDG-1o)
Defective DPM2 causes DPM2-CDG (CDG-1u)

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Congenital muscular dystrophy with intellectual disability and severe epilepsy	Likely pathogenic; Pathogenic	rs549450795, rs1185338798, rs2539553454, rs2539556000, rs2539558352, rs397514503, rs797044467, rs1349389319	RCV001375849 RCV001375850 RCV003150595 RCV003536548 RCV003649640 RCV000032641 RCV000032642 RCV000779570	★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IU	—	CTD, HPO CTD, HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DPM2-related disorder	Likely benign; Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLAUCOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY ANGLE CLOSURE GLAUCOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Angle Closure Glaucoma	Angle Closure Glaucoma	BEFREE	31377279		★☆☆☆☆ Found in Text Mining only
Antithrombin III Deficiency	Antithrombin Deficiency	HPO_DG			★☆☆☆☆ Found in Text Mining only
Byzanthine arch palate	High palate	HPO_DG			★☆☆☆☆ Found in Text Mining only
Cerebellar Hypoplasia	Cerebellar Hypoplasia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Congenital contracture	Congenital contracture	HPO_DG			★☆☆☆☆ Found in Text Mining only
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iu	Congenital disorder of glycosylation	GENOMICS_ENGLAND_DG	19901254, 23109149, 26453362		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iu	Congenital disorder of glycosylation	UNIPROT_DG	23109149		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iu	Congenital disorder of glycosylation	ORPHANET_DG	23109149		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iu	Congenital disorder of glycosylation	CLINVAR_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE Iu	Congenital disorder of glycosylation	CTD_human_DG			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Congenital Disorders of Glycosylation	Congenital disorder of glycosylation	BEFREE	23109149		★☆☆☆☆ Found in Text Mining only
Congenital Disorders of Glycosylation	Congenital disorder of glycosylation	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Congenital muscular dystrophy with intellectual disability and severe epilepsy	Congenital Muscular Dystrophy With Intellectual Disability And Epilepsy	Orphanet			★★★★★ ClinVar: Pathogenic / Likely Pathogenic (≥5 Variants)
Developmental Disabilities	Developmental disability	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	23109149		★☆☆☆☆ Found in Text Mining only
Epileptic encephalopathy	Epileptic encephalopathy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Exfoliation Syndrome	Exfoliation Syndrome	BEFREE	28505344		★☆☆☆☆ Found in Text Mining only
Generalized clonic seizures	Clonic Seizures	HPO_DG			★☆☆☆☆ Found in Text Mining only
Generalized myoclonic seizures	Myoclonic Seizures	HPO_DG			★☆☆☆☆ Found in Text Mining only
Glaucoma	Glaucoma	BEFREE	28505344		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Glycogen Storage Disease XIV	Glycogen storage disease	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Micrognathism	Micrognathism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Muscular Dystrophy	Muscular dystrophy	BEFREE	23109149		★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★☆☆☆☆ Found in Text Mining only
Osteopenia	Osteopenia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Parkinsonian Disorders	Parkinson Disease	BEFREE	29523295		★☆☆☆☆ Found in Text Mining only
Primary angle-closure glaucoma	Angle closure glaucoma	BEFREE	31377279		★☆☆☆☆ Found in Text Mining only
Respiratory Distress Syndrome, Newborn	Congenital alveolar dysplasia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Sarcoidosis	Sarcoidosis	BEFREE	19946248		★☆☆☆☆ Found in Text Mining only
Scoliosis, unspecified	Scoliosis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Seizures	Seizures	Pubtator	33129689	Associate	★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	HPO_DG			★☆☆☆☆ Found in Text Mining only
Trigonocephaly	Trigonocephaly	HPO_DG			★☆☆☆☆ Found in Text Mining only