RIOK3 (RIO kinase 3)

Gene

• Entrez ID: 8780
• Gene name: RIO kinase 3
• Gene symbol: RIOK3
• Synonyms (NCBI Gene): SUDD
• Chromosome: 18
• Chromosome location: 18q11.2
• Summary: This gene was first identified by the similarity of its product to the Aspergillus nidulans SUDD protein. This gene is now recognized as a member of the right open reading frame (RIO) kinase gene family. This gene encodes a serine/threonine kinase that lo

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052360	hsa-let-7a-5p	CLASH	23622248
MIRT051978	hsa-let-7b-5p	CLASH	23622248
MIRT051135	hsa-miR-16-5p	CLASH	23622248
MIRT047563	hsa-miR-10a-5p	CLASH	23622248
MIRT437594	hsa-miR-140-5p	Microarray, qRT-PCR	22815788
MIRT437724	hsa-miR-29a-3p	Microarray, qRT-PCR	22815788
MIRT437725	hsa-miR-29b-3p	Microarray, qRT-PCR	22815788
MIRT437726	hsa-miR-29c-3p	Microarray, qRT-PCR	22815788
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT615736	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT615735	hsa-miR-3940-5p	HITS-CLIP	23824327
MIRT615734	hsa-miR-4507	HITS-CLIP	23824327
MIRT615733	hsa-miR-6839-3p	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT614809	hsa-miR-3690	HITS-CLIP	23824327
MIRT614808	hsa-miR-4254	HITS-CLIP	23824327
MIRT614807	hsa-miR-1273f	HITS-CLIP	23824327
MIRT614806	hsa-miR-4683	HITS-CLIP	23824327
MIRT614805	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT614804	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT614803	hsa-miR-1270	HITS-CLIP	23824327
MIRT614802	hsa-miR-620	HITS-CLIP	23824327
MIRT614801	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT614800	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT1307492	hsa-miR-106a	CLIP-seq
MIRT1307493	hsa-miR-106b	CLIP-seq
MIRT1307494	hsa-miR-1243	CLIP-seq
MIRT1307495	hsa-miR-1245	CLIP-seq
MIRT1307496	hsa-miR-1254	CLIP-seq
MIRT1307497	hsa-miR-1297	CLIP-seq
MIRT1307498	hsa-miR-1321	CLIP-seq
MIRT1307499	hsa-miR-150	CLIP-seq
MIRT1307500	hsa-miR-17	CLIP-seq
MIRT1307501	hsa-miR-20a	CLIP-seq
MIRT1307502	hsa-miR-20b	CLIP-seq
MIRT1307503	hsa-miR-224	CLIP-seq
MIRT1307504	hsa-miR-26a	CLIP-seq
MIRT1307505	hsa-miR-26b	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT1307509	hsa-miR-302a	CLIP-seq
MIRT1307510	hsa-miR-302b	CLIP-seq
MIRT1307511	hsa-miR-302c	CLIP-seq
MIRT1307512	hsa-miR-302d	CLIP-seq
MIRT1307513	hsa-miR-302e	CLIP-seq
MIRT1307514	hsa-miR-3064-3p	CLIP-seq
MIRT1307515	hsa-miR-3116	CLIP-seq
MIRT1307516	hsa-miR-3136-5p	CLIP-seq
MIRT1307517	hsa-miR-3145-5p	CLIP-seq
MIRT1307518	hsa-miR-3161	CLIP-seq
MIRT1307519	hsa-miR-3163	CLIP-seq
MIRT1307520	hsa-miR-320a	CLIP-seq
MIRT1307521	hsa-miR-320b	CLIP-seq
MIRT1307522	hsa-miR-320c	CLIP-seq
MIRT1307523	hsa-miR-320d	CLIP-seq
MIRT1307524	hsa-miR-3545-3p	CLIP-seq
MIRT1307525	hsa-miR-3617	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT1307527	hsa-miR-3663-5p	CLIP-seq
MIRT1307528	hsa-miR-3689d	CLIP-seq
MIRT1307529	hsa-miR-372	CLIP-seq
MIRT1307530	hsa-miR-373	CLIP-seq
MIRT1307531	hsa-miR-4270	CLIP-seq
MIRT1307532	hsa-miR-4282	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT1307534	hsa-miR-4429	CLIP-seq
MIRT1307535	hsa-miR-4439	CLIP-seq
MIRT1307536	hsa-miR-4441	CLIP-seq
MIRT1307537	hsa-miR-4464	CLIP-seq
MIRT1307538	hsa-miR-4465	CLIP-seq
MIRT1307539	hsa-miR-4519	CLIP-seq
MIRT1307540	hsa-miR-4532	CLIP-seq
MIRT1307541	hsa-miR-4635	CLIP-seq
MIRT1307542	hsa-miR-4680-5p	CLIP-seq
MIRT1307543	hsa-miR-4695-3p	CLIP-seq
MIRT1307544	hsa-miR-4713-5p	CLIP-seq
MIRT1307545	hsa-miR-4731-5p	CLIP-seq
MIRT1307546	hsa-miR-4739	CLIP-seq
MIRT1307547	hsa-miR-4744	CLIP-seq
MIRT1307548	hsa-miR-4748	CLIP-seq
MIRT1307549	hsa-miR-4756-5p	CLIP-seq
MIRT1307550	hsa-miR-4766-5p	CLIP-seq
MIRT1307551	hsa-miR-4772-3p	CLIP-seq
MIRT1307552	hsa-miR-483-3p	CLIP-seq
MIRT1307553	hsa-miR-498	CLIP-seq
MIRT1307554	hsa-miR-5095	CLIP-seq
MIRT1307555	hsa-miR-512-3p	CLIP-seq
MIRT1307556	hsa-miR-519d	CLIP-seq
MIRT1307557	hsa-miR-520a-3p	CLIP-seq
MIRT1307558	hsa-miR-520b	CLIP-seq
MIRT1307559	hsa-miR-520c-3p	CLIP-seq
MIRT1307560	hsa-miR-520d-3p	CLIP-seq
MIRT1307561	hsa-miR-520e	CLIP-seq
MIRT1307562	hsa-miR-520g	CLIP-seq
MIRT1307563	hsa-miR-520h	CLIP-seq
MIRT1307564	hsa-miR-532-3p	CLIP-seq
MIRT1307565	hsa-miR-550a	CLIP-seq
MIRT1307566	hsa-miR-552	CLIP-seq
MIRT1307567	hsa-miR-561	CLIP-seq
MIRT1307568	hsa-miR-579	CLIP-seq
MIRT1307569	hsa-miR-640	CLIP-seq
MIRT1307570	hsa-miR-641	CLIP-seq
MIRT1307571	hsa-miR-661	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT1307573	hsa-miR-93	CLIP-seq
MIRT1307574	hsa-miR-934	CLIP-seq
MIRT1307575	hsa-miR-943	CLIP-seq
MIRT1553110	hsa-miR-4716-5p	CLIP-seq
MIRT2091133	hsa-miR-1238	CLIP-seq
MIRT2091134	hsa-miR-1256	CLIP-seq
MIRT2091135	hsa-miR-1271	CLIP-seq
MIRT1307497	hsa-miR-1297	CLIP-seq
MIRT2091136	hsa-miR-182	CLIP-seq
MIRT1307504	hsa-miR-26a	CLIP-seq
MIRT1307505	hsa-miR-26b	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT2091137	hsa-miR-3124-3p	CLIP-seq
MIRT2091138	hsa-miR-3133	CLIP-seq
MIRT2091139	hsa-miR-3145-3p	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT2091140	hsa-miR-3689a-5p	CLIP-seq
MIRT2091141	hsa-miR-3689b	CLIP-seq
MIRT2091142	hsa-miR-3689e	CLIP-seq
MIRT2091143	hsa-miR-3689f	CLIP-seq
MIRT2091144	hsa-miR-4263	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT1307538	hsa-miR-4465	CLIP-seq
MIRT1307540	hsa-miR-4532	CLIP-seq
MIRT2091145	hsa-miR-4642	CLIP-seq
MIRT2091146	hsa-miR-4668-5p	CLIP-seq
MIRT2091147	hsa-miR-4691-5p	CLIP-seq
MIRT1307543	hsa-miR-4695-3p	CLIP-seq
MIRT2091148	hsa-miR-4716-3p	CLIP-seq
MIRT1553110	hsa-miR-4716-5p	CLIP-seq
MIRT2091149	hsa-miR-4717-3p	CLIP-seq
MIRT2091150	hsa-miR-4735-5p	CLIP-seq
MIRT1307550	hsa-miR-4766-5p	CLIP-seq
MIRT1307551	hsa-miR-4772-3p	CLIP-seq
MIRT1307552	hsa-miR-483-3p	CLIP-seq
MIRT1307553	hsa-miR-498	CLIP-seq
MIRT2091151	hsa-miR-576-5p	CLIP-seq
MIRT2091152	hsa-miR-624	CLIP-seq
MIRT2091153	hsa-miR-625	CLIP-seq
MIRT2091154	hsa-miR-758	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT2091155	hsa-miR-96	CLIP-seq
MIRT1307494	hsa-miR-1243	CLIP-seq
MIRT1307495	hsa-miR-1245	CLIP-seq
MIRT2315874	hsa-miR-1295	CLIP-seq
MIRT2315875	hsa-miR-1976	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT1307514	hsa-miR-3064-3p	CLIP-seq
MIRT2315876	hsa-miR-3126-3p	CLIP-seq
MIRT2315877	hsa-miR-3128	CLIP-seq
MIRT1307516	hsa-miR-3136-5p	CLIP-seq
MIRT2315878	hsa-miR-3149	CLIP-seq
MIRT2315879	hsa-miR-3168	CLIP-seq
MIRT1307520	hsa-miR-320a	CLIP-seq
MIRT1307521	hsa-miR-320b	CLIP-seq
MIRT1307522	hsa-miR-320c	CLIP-seq
MIRT1307523	hsa-miR-320d	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT2315880	hsa-miR-3673	CLIP-seq
MIRT2315881	hsa-miR-3692	CLIP-seq
MIRT2315882	hsa-miR-411	CLIP-seq
MIRT2315883	hsa-miR-4279	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT2315884	hsa-miR-4421	CLIP-seq
MIRT2315885	hsa-miR-4423-5p	CLIP-seq
MIRT1307534	hsa-miR-4429	CLIP-seq
MIRT1307535	hsa-miR-4439	CLIP-seq
MIRT1307539	hsa-miR-4519	CLIP-seq
MIRT1307540	hsa-miR-4532	CLIP-seq
MIRT2091146	hsa-miR-4668-5p	CLIP-seq
MIRT1307543	hsa-miR-4695-3p	CLIP-seq
MIRT2091148	hsa-miR-4716-3p	CLIP-seq
MIRT1553110	hsa-miR-4716-5p	CLIP-seq
MIRT2091149	hsa-miR-4717-3p	CLIP-seq
MIRT2315886	hsa-miR-4720-5p	CLIP-seq
MIRT2315887	hsa-miR-4743	CLIP-seq
MIRT1307551	hsa-miR-4772-3p	CLIP-seq
MIRT2315888	hsa-miR-4799-3p	CLIP-seq
MIRT1307552	hsa-miR-483-3p	CLIP-seq
MIRT1307553	hsa-miR-498	CLIP-seq
MIRT2315889	hsa-miR-548c-3p	CLIP-seq
MIRT2315890	hsa-miR-622	CLIP-seq
MIRT2091152	hsa-miR-624	CLIP-seq
MIRT2091153	hsa-miR-625	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT1307575	hsa-miR-943	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT2091146	hsa-miR-4668-5p	CLIP-seq
MIRT2091148	hsa-miR-4716-3p	CLIP-seq
MIRT2091149	hsa-miR-4717-3p	CLIP-seq
MIRT2091152	hsa-miR-624	CLIP-seq
MIRT2091153	hsa-miR-625	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT2315874	hsa-miR-1295	CLIP-seq
MIRT2458255	hsa-miR-181a	CLIP-seq
MIRT2458256	hsa-miR-181b	CLIP-seq
MIRT2458257	hsa-miR-181c	CLIP-seq
MIRT2458258	hsa-miR-181d	CLIP-seq
MIRT2458259	hsa-miR-27a	CLIP-seq
MIRT2458260	hsa-miR-27b	CLIP-seq
MIRT2315878	hsa-miR-3149	CLIP-seq
MIRT2458261	hsa-miR-3613-3p	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT2458262	hsa-miR-380	CLIP-seq
MIRT2315882	hsa-miR-411	CLIP-seq
MIRT2458263	hsa-miR-4262	CLIP-seq
MIRT2458264	hsa-miR-4446-5p	CLIP-seq
MIRT2458265	hsa-miR-4715-3p	CLIP-seq
MIRT2091150	hsa-miR-4735-5p	CLIP-seq
MIRT2315887	hsa-miR-4743	CLIP-seq
MIRT2458266	hsa-miR-4755-5p	CLIP-seq
MIRT2458267	hsa-miR-4775	CLIP-seq
MIRT2458268	hsa-miR-513a-5p	CLIP-seq
MIRT2458269	hsa-miR-590-3p	CLIP-seq
MIRT2458270	hsa-miR-607	CLIP-seq
MIRT2458271	hsa-miR-642a	CLIP-seq
MIRT2458272	hsa-miR-941	CLIP-seq
MIRT2611900	hsa-miR-1200	CLIP-seq
MIRT2611901	hsa-miR-1226	CLIP-seq
MIRT2611902	hsa-miR-1227	CLIP-seq
MIRT2611903	hsa-miR-1253	CLIP-seq
MIRT2611904	hsa-miR-1276	CLIP-seq
MIRT2611905	hsa-miR-1285	CLIP-seq
MIRT2315874	hsa-miR-1295	CLIP-seq
MIRT1307497	hsa-miR-1297	CLIP-seq
MIRT2611906	hsa-miR-1299	CLIP-seq
MIRT2611907	hsa-miR-141	CLIP-seq
MIRT2458255	hsa-miR-181a	CLIP-seq
MIRT2458256	hsa-miR-181b	CLIP-seq
MIRT2458257	hsa-miR-181c	CLIP-seq
MIRT2458258	hsa-miR-181d	CLIP-seq
MIRT2315875	hsa-miR-1976	CLIP-seq
MIRT2611908	hsa-miR-200a	CLIP-seq
MIRT2611909	hsa-miR-2117	CLIP-seq
MIRT1307503	hsa-miR-224	CLIP-seq
MIRT1307504	hsa-miR-26a	CLIP-seq
MIRT1307505	hsa-miR-26b	CLIP-seq
MIRT2458259	hsa-miR-27a	CLIP-seq
MIRT2458260	hsa-miR-27b	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT1307514	hsa-miR-3064-3p	CLIP-seq
MIRT2315878	hsa-miR-3149	CLIP-seq
MIRT2611910	hsa-miR-3152-3p	CLIP-seq
MIRT1307519	hsa-miR-3163	CLIP-seq
MIRT2315879	hsa-miR-3168	CLIP-seq
MIRT2611911	hsa-miR-3187-5p	CLIP-seq
MIRT2611912	hsa-miR-326	CLIP-seq
MIRT2611913	hsa-miR-330-5p	CLIP-seq
MIRT2611914	hsa-miR-34b	CLIP-seq
MIRT2611915	hsa-miR-3607-3p	CLIP-seq
MIRT2458261	hsa-miR-3613-3p	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT2611916	hsa-miR-3686	CLIP-seq
MIRT2611917	hsa-miR-375	CLIP-seq
MIRT2611918	hsa-miR-378g	CLIP-seq
MIRT2611919	hsa-miR-3919	CLIP-seq
MIRT2611920	hsa-miR-3921	CLIP-seq
MIRT2315882	hsa-miR-411	CLIP-seq
MIRT2611921	hsa-miR-4251	CLIP-seq
MIRT2611922	hsa-miR-4261	CLIP-seq
MIRT2458263	hsa-miR-4262	CLIP-seq
MIRT2611923	hsa-miR-4272	CLIP-seq
MIRT2611924	hsa-miR-4273	CLIP-seq
MIRT2315883	hsa-miR-4279	CLIP-seq
MIRT2611925	hsa-miR-4301	CLIP-seq
MIRT2611926	hsa-miR-4311	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT2611927	hsa-miR-4324	CLIP-seq
MIRT2315884	hsa-miR-4421	CLIP-seq
MIRT2611928	hsa-miR-4461	CLIP-seq
MIRT1307538	hsa-miR-4465	CLIP-seq
MIRT2611929	hsa-miR-4486	CLIP-seq
MIRT1307539	hsa-miR-4519	CLIP-seq
MIRT1307540	hsa-miR-4532	CLIP-seq
MIRT2611930	hsa-miR-4640-5p	CLIP-seq
MIRT2611931	hsa-miR-4652-3p	CLIP-seq
MIRT2611932	hsa-miR-4653-5p	CLIP-seq
MIRT2611933	hsa-miR-4663	CLIP-seq
MIRT2091146	hsa-miR-4668-5p	CLIP-seq
MIRT2611934	hsa-miR-4676-5p	CLIP-seq
MIRT2611935	hsa-miR-4677-5p	CLIP-seq
MIRT1307543	hsa-miR-4695-3p	CLIP-seq
MIRT2611936	hsa-miR-4705	CLIP-seq
MIRT2458265	hsa-miR-4715-3p	CLIP-seq
MIRT2091148	hsa-miR-4716-3p	CLIP-seq
MIRT2091149	hsa-miR-4717-3p	CLIP-seq
MIRT2611937	hsa-miR-4726-5p	CLIP-seq
MIRT2611938	hsa-miR-4728-3p	CLIP-seq
MIRT2611939	hsa-miR-4733-3p	CLIP-seq
MIRT2091150	hsa-miR-4735-5p	CLIP-seq
MIRT2315887	hsa-miR-4743	CLIP-seq
MIRT1307547	hsa-miR-4744	CLIP-seq
MIRT1307550	hsa-miR-4766-5p	CLIP-seq
MIRT2611940	hsa-miR-4768-5p	CLIP-seq
MIRT1307551	hsa-miR-4772-3p	CLIP-seq
MIRT2458267	hsa-miR-4775	CLIP-seq
MIRT2611941	hsa-miR-4797-5p	CLIP-seq
MIRT2611942	hsa-miR-4803	CLIP-seq
MIRT1307552	hsa-miR-483-3p	CLIP-seq
MIRT2611943	hsa-miR-494	CLIP-seq
MIRT1307553	hsa-miR-498	CLIP-seq
MIRT2611944	hsa-miR-513a-3p	CLIP-seq
MIRT2458268	hsa-miR-513a-5p	CLIP-seq
MIRT2611945	hsa-miR-539	CLIP-seq
MIRT2611946	hsa-miR-544b	CLIP-seq
MIRT2315889	hsa-miR-548c-3p	CLIP-seq
MIRT1307567	hsa-miR-561	CLIP-seq
MIRT2611947	hsa-miR-570	CLIP-seq
MIRT2611948	hsa-miR-575	CLIP-seq
MIRT1307568	hsa-miR-579	CLIP-seq
MIRT2611949	hsa-miR-580	CLIP-seq
MIRT2611950	hsa-miR-583	CLIP-seq
MIRT2611951	hsa-miR-587	CLIP-seq
MIRT2458269	hsa-miR-590-3p	CLIP-seq
MIRT2611952	hsa-miR-610	CLIP-seq
MIRT2611953	hsa-miR-612	CLIP-seq
MIRT2611954	hsa-miR-618	CLIP-seq
MIRT2315890	hsa-miR-622	CLIP-seq
MIRT2091152	hsa-miR-624	CLIP-seq
MIRT2091153	hsa-miR-625	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT2611955	hsa-miR-875-3p	CLIP-seq
MIRT2611956	hsa-miR-885-3p	CLIP-seq
MIRT2458272	hsa-miR-941	CLIP-seq
MIRT2611900	hsa-miR-1200	CLIP-seq
MIRT2611902	hsa-miR-1227	CLIP-seq
MIRT2611903	hsa-miR-1253	CLIP-seq
MIRT2611904	hsa-miR-1276	CLIP-seq
MIRT2611905	hsa-miR-1285	CLIP-seq
MIRT2315874	hsa-miR-1295	CLIP-seq
MIRT1307497	hsa-miR-1297	CLIP-seq
MIRT2611906	hsa-miR-1299	CLIP-seq
MIRT2458255	hsa-miR-181a	CLIP-seq
MIRT2458256	hsa-miR-181b	CLIP-seq
MIRT2458257	hsa-miR-181c	CLIP-seq
MIRT2458258	hsa-miR-181d	CLIP-seq
MIRT2315875	hsa-miR-1976	CLIP-seq
MIRT1307503	hsa-miR-224	CLIP-seq
MIRT1307504	hsa-miR-26a	CLIP-seq
MIRT1307505	hsa-miR-26b	CLIP-seq
MIRT2458259	hsa-miR-27a	CLIP-seq
MIRT2458260	hsa-miR-27b	CLIP-seq
MIRT1307506	hsa-miR-29a	CLIP-seq
MIRT1307507	hsa-miR-29b	CLIP-seq
MIRT1307508	hsa-miR-29c	CLIP-seq
MIRT1307514	hsa-miR-3064-3p	CLIP-seq
MIRT2315878	hsa-miR-3149	CLIP-seq
MIRT1307519	hsa-miR-3163	CLIP-seq
MIRT2611911	hsa-miR-3187-5p	CLIP-seq
MIRT2611912	hsa-miR-326	CLIP-seq
MIRT2611913	hsa-miR-330-5p	CLIP-seq
MIRT2458261	hsa-miR-3613-3p	CLIP-seq
MIRT1307526	hsa-miR-3622b-5p	CLIP-seq
MIRT2611917	hsa-miR-375	CLIP-seq
MIRT2611918	hsa-miR-378g	CLIP-seq
MIRT2611919	hsa-miR-3919	CLIP-seq
MIRT2315882	hsa-miR-411	CLIP-seq
MIRT2611921	hsa-miR-4251	CLIP-seq
MIRT2611922	hsa-miR-4261	CLIP-seq
MIRT2458263	hsa-miR-4262	CLIP-seq
MIRT2611924	hsa-miR-4273	CLIP-seq
MIRT2315883	hsa-miR-4279	CLIP-seq
MIRT2611925	hsa-miR-4301	CLIP-seq
MIRT2611926	hsa-miR-4311	CLIP-seq
MIRT1307533	hsa-miR-4317	CLIP-seq
MIRT2611927	hsa-miR-4324	CLIP-seq
MIRT2315884	hsa-miR-4421	CLIP-seq
MIRT2611928	hsa-miR-4461	CLIP-seq
MIRT1307538	hsa-miR-4465	CLIP-seq
MIRT2611929	hsa-miR-4486	CLIP-seq
MIRT1307539	hsa-miR-4519	CLIP-seq
MIRT1307540	hsa-miR-4532	CLIP-seq
MIRT2611930	hsa-miR-4640-5p	CLIP-seq
MIRT2611933	hsa-miR-4663	CLIP-seq
MIRT2091146	hsa-miR-4668-5p	CLIP-seq
MIRT2611935	hsa-miR-4677-5p	CLIP-seq
MIRT1307543	hsa-miR-4695-3p	CLIP-seq
MIRT2458265	hsa-miR-4715-3p	CLIP-seq
MIRT2091148	hsa-miR-4716-3p	CLIP-seq
MIRT2091149	hsa-miR-4717-3p	CLIP-seq
MIRT2611937	hsa-miR-4726-5p	CLIP-seq
MIRT2611938	hsa-miR-4728-3p	CLIP-seq
MIRT2091150	hsa-miR-4735-5p	CLIP-seq
MIRT2315887	hsa-miR-4743	CLIP-seq
MIRT1307547	hsa-miR-4744	CLIP-seq
MIRT2611940	hsa-miR-4768-5p	CLIP-seq
MIRT1307551	hsa-miR-4772-3p	CLIP-seq
MIRT2458267	hsa-miR-4775	CLIP-seq
MIRT2611941	hsa-miR-4797-5p	CLIP-seq
MIRT2611942	hsa-miR-4803	CLIP-seq
MIRT1307552	hsa-miR-483-3p	CLIP-seq
MIRT2611943	hsa-miR-494	CLIP-seq
MIRT1307553	hsa-miR-498	CLIP-seq
MIRT2611944	hsa-miR-513a-3p	CLIP-seq
MIRT2458268	hsa-miR-513a-5p	CLIP-seq
MIRT2611945	hsa-miR-539	CLIP-seq
MIRT2611946	hsa-miR-544b	CLIP-seq
MIRT2315889	hsa-miR-548c-3p	CLIP-seq
MIRT1307567	hsa-miR-561	CLIP-seq
MIRT2611947	hsa-miR-570	CLIP-seq
MIRT1307568	hsa-miR-579	CLIP-seq
MIRT2611949	hsa-miR-580	CLIP-seq
MIRT2611950	hsa-miR-583	CLIP-seq
MIRT2611951	hsa-miR-587	CLIP-seq
MIRT2458269	hsa-miR-590-3p	CLIP-seq
MIRT2611952	hsa-miR-610	CLIP-seq
MIRT2611953	hsa-miR-612	CLIP-seq
MIRT2611954	hsa-miR-618	CLIP-seq
MIRT2315890	hsa-miR-622	CLIP-seq
MIRT2091152	hsa-miR-624	CLIP-seq
MIRT2091153	hsa-miR-625	CLIP-seq
MIRT1307572	hsa-miR-767-5p	CLIP-seq
MIRT2611955	hsa-miR-875-3p	CLIP-seq
MIRT2458272	hsa-miR-941	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002376	Process	Immune system process	IEA
GO:0003824	Function	Catalytic activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	25865883
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	19557502, 21988832, 24807708, 25865883
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	TAS
GO:0007059	Process	Chromosome segregation	TAS	9602165
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030490	Process	Maturation of SSU-rRNA	IBA
GO:0030490	Process	Maturation of SSU-rRNA	IMP	22418843
GO:0030688	Component	Preribosome, small subunit precursor	IBA
GO:0030688	Component	Preribosome, small subunit precursor	IDA	22072790, 22418843
GO:0031333	Process	Negative regulation of protein-containing complex assembly	IDA	25865883
GO:0032728	Process	Positive regulation of interferon-beta production	IMP	24807708
GO:0039534	Process	Negative regulation of MDA-5 signaling pathway	IMP	25865883
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	19557502
GO:0045087	Process	Innate immune response	IEA
GO:0045089	Process	Positive regulation of innate immune response	IMP	24807708
GO:0046872	Function	Metal ion binding	IEA
GO:0051607	Process	Defense response to virus	IEA
GO:0071359	Process	Cellular response to dsRNA	IMP	24807708
GO:0089720	Function	Caspase binding	IDA	19557502
GO:0098586	Process	Cellular response to virus	IMP	24807708
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1990786	Process	Cellular response to dsDNA	IMP	24807708

Other IDs

• MIM: 603579
• HGNC: 11451
• e!Ensembl: ENSG00000101782

Protein

• UniProt ID: O14730
• Protein name: Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)
• Protein function: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMe
• PDB: 8ZDB, 8ZDC, 8ZDD
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01163	RIO1	264 → 464		Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:9602165}.
• Sequence:

  MDLVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKELQLEEEAAVFPEVA
  VAEGPFITGENIDTSSDLMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYRKVH
  PYEDSDSSEDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARME
  NFAPEFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLL
  MYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFK
  NRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMS
  FIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVW
  LIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEAD
  FLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE

• Sequence length: 519

Pathways

Reactome:

Major pathway of rRNA processing in the nucleolus and cytosol

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OCULAR HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma of pancreas	Pancreatic adenocarcinoma	BEFREE	20553613		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	32193444	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	36880835	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29233656		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	25486436, 29233656		★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	27856519	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	LHGDN	19050074		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	20053773	Associate	★☆☆☆☆ Found in Text Mining only