Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Other IDs Pathways Associated diseases
Entrez ID	8681
Gene name	JMJD7-PLA2G4B readthrough
Gene symbol	JMJD7-PLA2G4B
Synonyms (NCBI Gene)	HsT16992cPLA2-beta
Chromosome	15
Chromosome location	15q15.1
Summary	This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino ac

Show/Hide all (3)

miRTarBase ID	miRNA	Experiments
MIRT1077092	hsa-miR-4300	CLIP-seq
MIRT1077093	hsa-miR-4687-5p	CLIP-seq
MIRT1077094	hsa-miR-920	CLIP-seq

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Interactions View interactions

	KEGG		Reactome
	Glycerophospholipid metabolism Ether lipid metabolism Arachidonic acid metabolism Linoleic acid metabolism alpha-Linolenic acid metabolism Metabolic pathways MAPK signaling pathway Ras signaling pathway Phospholipase D signaling pathway Necroptosis Vascular smooth muscle contraction VEGF signaling pathway Platelet activation Fc epsilon RI signaling pathway Fc gamma R-mediated phagocytosis Glutamatergic synapse Serotonergic synapse Long-term depression Inflammatory mediator regulation of TRP channels GnRH signaling pathway Ovarian steroidogenesis Oxytocin signaling pathway Choline metabolism in cancer		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PG Hydrolysis of LPC Synthesis of PA XBP1(S) activates chaperone genes

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
JMJD7-PLA2G4B-related disorder	Likely benign; Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Melanoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	28030848		★★★★★ ★☆☆☆☆ Found in Text Mining only

JMJD7-PLA2G4B (JMJD7-PLA2G4B readthrough)