UNC5C (unc-5 netrin receptor C)

Gene

• Entrez ID: 8633
• Gene name: Unc-5 netrin receptor C
• Gene symbol: UNC5C
• Synonyms (NCBI Gene): UNC5H3
• Chromosome: 4
• Chromosome location: 4q22.3
• Summary: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as rep

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017932	hsa-miR-335-5p	Microarray	18185580
MIRT495575	hsa-miR-936	PAR-CLIP	22291592
MIRT495574	hsa-miR-199a-3p	PAR-CLIP	22291592
MIRT495573	hsa-miR-199b-3p	PAR-CLIP	22291592
MIRT495572	hsa-miR-3129-5p	PAR-CLIP	22291592
MIRT495571	hsa-miR-5088-3p	PAR-CLIP	22291592
MIRT495570	hsa-miR-6806-5p	PAR-CLIP	22291592
MIRT495569	hsa-miR-222-5p	PAR-CLIP	22291592
MIRT495568	hsa-miR-500a-5p	PAR-CLIP	22291592
MIRT495567	hsa-miR-3929	PAR-CLIP	22291592
MIRT495566	hsa-miR-4419b	PAR-CLIP	22291592
MIRT495565	hsa-miR-4478	PAR-CLIP	22291592
MIRT495564	hsa-miR-93-3p	PAR-CLIP	22291592
MIRT495563	hsa-miR-6762-3p	PAR-CLIP	22291592
MIRT444572	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT444571	hsa-miR-323a-3p	PAR-CLIP	22100165
MIRT444570	hsa-miR-4496	PAR-CLIP	22100165
MIRT444569	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT444568	hsa-miR-4477b	PAR-CLIP	22100165
MIRT495575	hsa-miR-936	PAR-CLIP	22291592
MIRT495574	hsa-miR-199a-3p	PAR-CLIP	22291592
MIRT495573	hsa-miR-199b-3p	PAR-CLIP	22291592
MIRT495572	hsa-miR-3129-5p	PAR-CLIP	22291592
MIRT495571	hsa-miR-5088-3p	PAR-CLIP	22291592
MIRT495570	hsa-miR-6806-5p	PAR-CLIP	22291592
MIRT495569	hsa-miR-222-5p	PAR-CLIP	22291592
MIRT495568	hsa-miR-500a-5p	PAR-CLIP	22291592
MIRT495567	hsa-miR-3929	PAR-CLIP	22291592
MIRT495566	hsa-miR-4419b	PAR-CLIP	22291592
MIRT495565	hsa-miR-4478	PAR-CLIP	22291592
MIRT495564	hsa-miR-93-3p	PAR-CLIP	22291592
MIRT495563	hsa-miR-6762-3p	PAR-CLIP	22291592
MIRT444572	hsa-miR-651-3p	PAR-CLIP	22100165
MIRT444571	hsa-miR-323a-3p	PAR-CLIP	22100165
MIRT444570	hsa-miR-4496	PAR-CLIP	22100165
MIRT444569	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT444568	hsa-miR-4477b	PAR-CLIP	22100165
MIRT1475488	hsa-miR-103a	CLIP-seq
MIRT1475489	hsa-miR-103b	CLIP-seq
MIRT1475490	hsa-miR-107	CLIP-seq
MIRT1475491	hsa-miR-1184	CLIP-seq
MIRT1475492	hsa-miR-1197	CLIP-seq
MIRT1475493	hsa-miR-1205	CLIP-seq
MIRT1475494	hsa-miR-1206	CLIP-seq
MIRT1475495	hsa-miR-1224-5p	CLIP-seq
MIRT1475496	hsa-miR-1231	CLIP-seq
MIRT1475497	hsa-miR-1252	CLIP-seq
MIRT1475498	hsa-miR-1273g	CLIP-seq
MIRT739281	hsa-miR-132	CLIP-seq
MIRT1475499	hsa-miR-184	CLIP-seq
MIRT1475500	hsa-miR-190	CLIP-seq
MIRT1475501	hsa-miR-190b	CLIP-seq
MIRT739282	hsa-miR-194	CLIP-seq
MIRT1475502	hsa-miR-204	CLIP-seq
MIRT1475503	hsa-miR-205	CLIP-seq
MIRT1475504	hsa-miR-211	CLIP-seq
MIRT739280	hsa-miR-212	CLIP-seq
MIRT1475505	hsa-miR-221	CLIP-seq
MIRT1475506	hsa-miR-222	CLIP-seq
MIRT1475507	hsa-miR-2355-3p	CLIP-seq
MIRT1475508	hsa-miR-2467-3p	CLIP-seq
MIRT1475509	hsa-miR-28-3p	CLIP-seq
MIRT1475510	hsa-miR-3127-3p	CLIP-seq
MIRT1475511	hsa-miR-3145-3p	CLIP-seq
MIRT1475512	hsa-miR-3151	CLIP-seq
MIRT1475513	hsa-miR-3158-5p	CLIP-seq
MIRT1475514	hsa-miR-3160-5p	CLIP-seq
MIRT1475515	hsa-miR-3170	CLIP-seq
MIRT740231	hsa-miR-340	CLIP-seq
MIRT1475516	hsa-miR-34b	CLIP-seq
MIRT1475517	hsa-miR-3613-5p	CLIP-seq
MIRT1475518	hsa-miR-3622a-3p	CLIP-seq
MIRT1475519	hsa-miR-3622b-3p	CLIP-seq
MIRT1475520	hsa-miR-3646	CLIP-seq
MIRT1475521	hsa-miR-3662	CLIP-seq
MIRT1475522	hsa-miR-3678-3p	CLIP-seq
MIRT1475523	hsa-miR-3679-3p	CLIP-seq
MIRT1475524	hsa-miR-3685	CLIP-seq
MIRT739279	hsa-miR-3688-3p	CLIP-seq
MIRT1475525	hsa-miR-3690	CLIP-seq
MIRT1475526	hsa-miR-376a	CLIP-seq
MIRT1475527	hsa-miR-376b	CLIP-seq
MIRT1475528	hsa-miR-376c	CLIP-seq
MIRT1475529	hsa-miR-3975	CLIP-seq
MIRT1475530	hsa-miR-4265	CLIP-seq
MIRT1475531	hsa-miR-4296	CLIP-seq
MIRT1475532	hsa-miR-4322	CLIP-seq
MIRT740229	hsa-miR-4427	CLIP-seq
MIRT1475533	hsa-miR-4446-5p	CLIP-seq
MIRT1475534	hsa-miR-4447	CLIP-seq
MIRT1475535	hsa-miR-4472	CLIP-seq
MIRT1475536	hsa-miR-4477a	CLIP-seq
MIRT1475537	hsa-miR-4494	CLIP-seq
MIRT1475538	hsa-miR-4499	CLIP-seq
MIRT1475539	hsa-miR-4513	CLIP-seq
MIRT1475540	hsa-miR-4646-3p	CLIP-seq
MIRT1475541	hsa-miR-4649-5p	CLIP-seq
MIRT1475542	hsa-miR-4659a-3p	CLIP-seq
MIRT1475543	hsa-miR-4659b-3p	CLIP-seq
MIRT1475544	hsa-miR-4699-5p	CLIP-seq
MIRT1475545	hsa-miR-4705	CLIP-seq
MIRT740230	hsa-miR-4724-5p	CLIP-seq
MIRT1475546	hsa-miR-4751	CLIP-seq
MIRT1475547	hsa-miR-4755-5p	CLIP-seq
MIRT1475548	hsa-miR-4756-3p	CLIP-seq
MIRT1475549	hsa-miR-4761-5p	CLIP-seq
MIRT1475550	hsa-miR-4764-3p	CLIP-seq
MIRT1475551	hsa-miR-4781-3p	CLIP-seq
MIRT1475552	hsa-miR-4804-5p	CLIP-seq
MIRT1475553	hsa-miR-490-3p	CLIP-seq
MIRT1475554	hsa-miR-491-3p	CLIP-seq
MIRT1475555	hsa-miR-491-5p	CLIP-seq
MIRT1475556	hsa-miR-501-3p	CLIP-seq
MIRT1475557	hsa-miR-502-3p	CLIP-seq
MIRT1475558	hsa-miR-502-5p	CLIP-seq
MIRT1475559	hsa-miR-513c	CLIP-seq
MIRT1475560	hsa-miR-514b-5p	CLIP-seq
MIRT1475561	hsa-miR-516b	CLIP-seq
MIRT1475562	hsa-miR-544	CLIP-seq
MIRT1475563	hsa-miR-579	CLIP-seq
MIRT1475564	hsa-miR-586	CLIP-seq
MIRT1475565	hsa-miR-619	CLIP-seq
MIRT1475566	hsa-miR-623	CLIP-seq
MIRT1475567	hsa-miR-654-3p	CLIP-seq
MIRT740228	hsa-miR-656	CLIP-seq
MIRT1475568	hsa-miR-676	CLIP-seq
MIRT1475569	hsa-miR-767-5p	CLIP-seq
MIRT739283	hsa-miR-802	CLIP-seq
MIRT1475570	hsa-miR-885-3p	CLIP-seq
MIRT739281	hsa-miR-132	CLIP-seq
MIRT739282	hsa-miR-194	CLIP-seq
MIRT739280	hsa-miR-212	CLIP-seq
MIRT739279	hsa-miR-3688-3p	CLIP-seq
MIRT739283	hsa-miR-802	CLIP-seq
MIRT1475494	hsa-miR-1206	CLIP-seq
MIRT2143294	hsa-miR-1207-5p	CLIP-seq
MIRT2143295	hsa-miR-1256	CLIP-seq
MIRT2143296	hsa-miR-134	CLIP-seq
MIRT2143297	hsa-miR-153	CLIP-seq
MIRT2143298	hsa-miR-183	CLIP-seq
MIRT2143299	hsa-miR-1909	CLIP-seq
MIRT1475508	hsa-miR-2467-3p	CLIP-seq
MIRT2143300	hsa-miR-3118	CLIP-seq
MIRT2143301	hsa-miR-3121-3p	CLIP-seq
MIRT2143302	hsa-miR-3171	CLIP-seq
MIRT2143303	hsa-miR-324-5p	CLIP-seq
MIRT2143304	hsa-miR-329	CLIP-seq
MIRT740231	hsa-miR-340	CLIP-seq
MIRT2143305	hsa-miR-362-3p	CLIP-seq
MIRT2143306	hsa-miR-3647-3p	CLIP-seq
MIRT2143307	hsa-miR-3660	CLIP-seq
MIRT2143308	hsa-miR-3908	CLIP-seq
MIRT2143309	hsa-miR-4257	CLIP-seq
MIRT2143310	hsa-miR-4314	CLIP-seq
MIRT2143311	hsa-miR-4488	CLIP-seq
MIRT2143312	hsa-miR-4502	CLIP-seq
MIRT2143313	hsa-miR-4505	CLIP-seq
MIRT2143314	hsa-miR-4526	CLIP-seq
MIRT2143315	hsa-miR-4667-5p	CLIP-seq
MIRT2143316	hsa-miR-4679	CLIP-seq
MIRT2143317	hsa-miR-4688	CLIP-seq
MIRT2143318	hsa-miR-4697-5p	CLIP-seq
MIRT2143319	hsa-miR-4700-5p	CLIP-seq
MIRT2143320	hsa-miR-4731-5p	CLIP-seq
MIRT2143321	hsa-miR-4733-5p	CLIP-seq
MIRT2143322	hsa-miR-4763-3p	CLIP-seq
MIRT2143323	hsa-miR-486-3p	CLIP-seq
MIRT2143324	hsa-miR-526b	CLIP-seq
MIRT2143325	hsa-miR-541	CLIP-seq
MIRT2143326	hsa-miR-548p	CLIP-seq
MIRT2143327	hsa-miR-556-3p	CLIP-seq
MIRT1475563	hsa-miR-579	CLIP-seq
MIRT2143328	hsa-miR-637	CLIP-seq
MIRT2143329	hsa-miR-654-5p	CLIP-seq
MIRT2143330	hsa-miR-943	CLIP-seq
MIRT1475493	hsa-miR-1205	CLIP-seq
MIRT2363570	hsa-miR-1276	CLIP-seq
MIRT2363571	hsa-miR-128	CLIP-seq
MIRT2143302	hsa-miR-3171	CLIP-seq
MIRT2363572	hsa-miR-3612	CLIP-seq
MIRT2363573	hsa-miR-3672	CLIP-seq
MIRT2363574	hsa-miR-3974	CLIP-seq
MIRT2363575	hsa-miR-4443	CLIP-seq
MIRT2363576	hsa-miR-4463	CLIP-seq
MIRT2363577	hsa-miR-583	CLIP-seq
MIRT2363578	hsa-miR-650	CLIP-seq
MIRT1475494	hsa-miR-1206	CLIP-seq
MIRT1475507	hsa-miR-2355-3p	CLIP-seq
MIRT2462930	hsa-miR-370	CLIP-seq
MIRT2462931	hsa-miR-4313	CLIP-seq
MIRT1475540	hsa-miR-4646-3p	CLIP-seq
MIRT1475568	hsa-miR-676	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005042	Function	Netrin receptor activity	IBA
GO:0005042	Function	Netrin receptor activity	IEA
GO:0005042	Function	Netrin receptor activity	TAS	9782087
GO:0005043	Function	Netrin receptor activity involved in chemorepulsion	IEA
GO:0005043	Function	Netrin receptor activity involved in chemorepulsion	ISS
GO:0005515	Function	Protein binding	IPI	22685302, 28483977
GO:0005886	Component	Plasma membrane	IDA	25419706
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007411	Process	Axon guidance	IBA
GO:0007411	Process	Axon guidance	IEA
GO:0007411	Process	Axon guidance	TAS
GO:0007420	Process	Brain development	IEA
GO:0007420	Process	Brain development	TAS	9782087
GO:0009986	Component	Cell surface	IEA
GO:0015631	Function	Tubulin binding	IEA
GO:0015631	Function	Tubulin binding	IPI	28483977
GO:0016020	Component	Membrane	IEA
GO:0019901	Function	Protein kinase binding	IPI	27068745
GO:0030027	Component	Lamellipodium	IEA
GO:0030027	Component	Lamellipodium	ISS
GO:0030175	Component	Filopodium	IEA
GO:0030175	Component	Filopodium	ISS
GO:0030334	Process	Regulation of cell migration	IEA
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0030426	Component	Growth cone	IEA
GO:0030426	Component	Growth cone	ISS
GO:0033564	Process	Anterior/posterior axon guidance	IEA
GO:0035234	Process	Ectopic germ cell programmed cell death	IEA
GO:0038007	Process	Netrin-activated signaling pathway	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0043025	Component	Neuronal cell body	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0045202	Component	Synapse	IEA
GO:0051094	Process	Positive regulation of developmental process	IEA
GO:0061643	Process	Chemorepulsion of axon	IEA
GO:0061643	Process	Chemorepulsion of axon	ISS
GO:1990791	Process	Dorsal root ganglion development	IDA	28483977
GO:2000243	Process	Positive regulation of reproductive process	IEA
GO:2001222	Process	Regulation of neuron migration	IEA

Other IDs

• MIM: 603610
• HGNC: 12569
• e!Ensembl: ENSG00000182168

Protein

• UniProt ID: O95185
• Protein name: Netrin receptor UNC5C (Protein unc-5 homolog 3) (Protein unc-5 homolog C)
• Protein function: Receptor for netrin required for axon guidance (By similarity). Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). NTN1/Netrin-1 binding might cause dissociation of UNC5C from p
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07679	I-set	167 → 257	Immunoglobulin I-set domain	Domain
  PF00090	TSP_1	264 → 313	Thrombospondin type 1 domain	Domain
  PF00090	TSP_1	317 → 367	Thrombospondin type 1 domain	Domain
  PF00791	ZU5	531 → 628	ZU5 domain	Family
  PF17217	UPA	678 → 817	UPA domain	Domain
  PF00531	Death	849 → 928	Death domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Mainly expressed in brain (PubMed:9782087). Expressed in temporal lobe cortical neurons and in neurons of the hippocampal pyramidal layer (PubMed:25419706). Also expressed in kidney (PubMed:9782087). Not expressed in developing or adul
• Sequence:

  MRKGLRATAARCGLGLGYLLQMLVLPALALLSASGTGSAAQDDDFFHELPETFPSDPPEP
  LPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHIVDERVDETSGLIVR
  EVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSL
  EQEVLLQCRPPEGIPVAEVEWLKNEDIIDPVEDRNFYITIDHNLIIKQARLSDTANYTCV
  AKNIVAKRKSTTATVIVYVNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCE
  GQSVQKIACTTLCPVDGRWTPWSKWSTCGTECTHWRRRECTAPAPKNGGKDCDGLVLQSK
  NCTDGLCMQTAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALN
  GGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIK
  VYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLG
  GHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMRPPMDDSQTLLTPVVSCGPPGAL
  LTRPVVLTMHHCADPNTEDWKILLKNQAAQGQWEDVVVVGEENFTTPCYIQLDAEACHIL
  TENLSTYALVGHSTTKAAAKRLKLAIFGPLCCSSLEYSIRVYCLDDTQDALKEILHLERQ
  MGGQLLEEPKALHFKGSTHNLRLSIHDIAHSLWKSKLLAKYQEIPFYHVWSGSQRNLHCT
  FTLERFSLNTVELVCKLCVRQVEGEGQIFQLNCTVSEEPTGIDLPLLDPANTITTVTGPS
  AFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLNLDRYLNYFATKSSPTGVILDLWEAQN
  FPDGNLSMLAAVLEEMGRHETVVSLAAEGQY

• Sequence length: 931

Pathways

KEGG:

Axon guidance

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE, FAMILIAL, 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ASTROCYTOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA, RENAL CELL	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLOR VISION DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MYOCARDIAL INFARCTION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYCYSTIC OVARY SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UNC5C-related disorder	Benign; Uncertain significance; Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenomatous Polyps	Adenomatous Polyposis	BEFREE	18054557, 28378635		★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	27036079, 33522999, 35001095	Associate	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease, Late Onset	Alzheimer disease	BEFREE	25419706, 27068745		★☆☆☆☆ Found in Text Mining only
Alzheimer`s Disease	Alzheimer disease	UNIPROT_DG	25419706, 27068745		★☆☆☆☆ Found in Text Mining only
Amyloidosis	Amyloidosis	BEFREE	25419706		★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Rheumatoid arthritis	Pubtator	19822088	Stimulate	★☆☆☆☆ Found in Text Mining only
Atrophy	Atrophy	Pubtator	30883345	Associate	★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	25316812		★☆☆☆☆ Found in Text Mining only
Brain Diseases	Brain disease	Pubtator	33522999	Associate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	31789389		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	18054557, 20032384, 24376576	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	19242752, 19331160, 20032384		★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	25316812		★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only
Chromophobe Renal Cell Carcinoma	Chromophobe Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Clear-cell metastatic renal cell carcinoma	Renal Carcinoma	BEFREE	21600761		★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Cognition disorder	Pubtator	30883345	Associate	★☆☆☆☆ Found in Text Mining only
Collecting Duct Carcinoma of the Kidney	Renal Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	18054557		★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	19331160, 20032384	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	17967459, 18054557, 19242752, 19331160, 21893118, 24415873, 26852919, 28378635, 29801399		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	12655055, 21893118		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	17967459, 18054557		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	18054557, 21893118, 33706130	Inhibit	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	19331160, 21893118, 24415873, 26852919, 28378635, 29801399, 38172877	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms Hereditary Nonpolyposis	Lynch syndrome	Pubtator	24415873	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21600761		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Coronary artery disease	GWASCAT_DG	29212778		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Degenerative polyarthritis	Arthritis	BEFREE	19822088		★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	GWASDB_DG	22763110		★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	26660111, 30883345		★☆☆☆☆ Found in Text Mining only
Intestinal Neoplasms	Intestinal Neoplasms	BEFREE	17967459, 21893118		★☆☆☆☆ Found in Text Mining only
Intestinal Neoplasms	Intestinal neoplasm	Pubtator	21893118	Associate	★☆☆☆☆ Found in Text Mining only
Kidney Neoplasms	Kidney neoplasm	Pubtator	33706130	Stimulate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	31789389		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of kidney	Kidney Cancer	BEFREE	12655055		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	25316812		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	17967459		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	18054557		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	16778180		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	12655055, 17967459, 19331160, 21600761, 28378635		★☆☆☆☆ Found in Text Mining only
Nervous System Diseases	Nervous system disease	Pubtator	30883345	Associate	★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	30883345	Associate	★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	15886715		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Osteoarthritis	Osteoarthritis	Pubtator	19822088	Stimulate	★☆☆☆☆ Found in Text Mining only
Papillary Renal Cell Carcinoma	Papillary Renal Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic ovary syndrome	Pubtator	32574161	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21600761		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	19822088		★☆☆☆☆ Found in Text Mining only
Sarcomatoid Renal Cell Carcinoma	Renal Carcinoma	CTD_human_DG	21600761		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	PSYGENET_DG	24956103		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sick Sinus Syndrome	Sick sinus syndrome	Pubtator	28378635	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	20032384, 24376576, 24415873	Associate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	25316812	Associate	★☆☆☆☆ Found in Text Mining only
Vitamin E Deficiency	Vitamin e deficiency	Pubtator	26446483	Associate	★☆☆☆☆ Found in Text Mining only