GTPBP10 (GTP binding protein 10)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 85865 |
| Gene name | GTP binding protein 10 |
| Gene symbol | GTPBP10 |
| Synonyms (NCBI Gene) |
ObgH2UG0751c10
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| Chromosome | 7 |
| Chromosome location | 7q21.13 |
| Summary | Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubM |
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miRNA
miRNA information provided by mirtarbase database.
677
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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A4D1E9 | |||||||||||||||
| Protein name | GTP-binding protein 10 (Protein obg homolog 2) (ObgH2) | |||||||||||||||
| Protein function | May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nucleolar architecture is observed. {ECO:0000269|PubMed:1 | |||||||||||||||
| PDB | 7OI6 , 8PK0 | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 387 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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