Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID	8543
Gene name	LIM domain only 4
Gene symbol	LMO4
Synonyms (NCBI Gene)	-
Chromosome	1
Chromosome location	1p22.3
Summary	This gene encodes a cysteine-rich protein that contains two LIM domains but lacks a DNA-binding homeodomain. The encoded protein may play a role as a transcriptional regulator or as an oncogene. [provided by RefSeq, Aug 2008]

329

Show/Hide all (329)

miRTarBase ID	miRNA	Experiments	Reference
MIRT734687	hsa-miR-409-3p	Luciferase reporter assay	33139574
MIRT1111915	hsa-miR-1197	CLIP-seq
MIRT1111916	hsa-miR-1273e	CLIP-seq
MIRT1111917	hsa-miR-1298	CLIP-seq
MIRT1111918	hsa-miR-214	CLIP-seq
MIRT1111919	hsa-miR-22	CLIP-seq
MIRT1111920	hsa-miR-24	CLIP-seq
MIRT1111921	hsa-miR-25	CLIP-seq
MIRT1111922	hsa-miR-302f	CLIP-seq
MIRT1111923	hsa-miR-3117-3p	CLIP-seq
MIRT1111924	hsa-miR-3140-3p	CLIP-seq
MIRT1111925	hsa-miR-3143	CLIP-seq
MIRT1111926	hsa-miR-3199	CLIP-seq
MIRT1111927	hsa-miR-32	CLIP-seq
MIRT1111928	hsa-miR-331-3p	CLIP-seq
MIRT1111929	hsa-miR-3619-5p	CLIP-seq
MIRT1111930	hsa-miR-363	CLIP-seq
MIRT1111931	hsa-miR-367	CLIP-seq
MIRT1111932	hsa-miR-3679-3p	CLIP-seq
MIRT1111933	hsa-miR-4278	CLIP-seq
MIRT1111934	hsa-miR-4291	CLIP-seq
MIRT1111935	hsa-miR-4325	CLIP-seq
MIRT1111936	hsa-miR-4437	CLIP-seq
MIRT1111937	hsa-miR-4446-5p	CLIP-seq
MIRT1111938	hsa-miR-4528	CLIP-seq
MIRT1111939	hsa-miR-4666-5p	CLIP-seq
MIRT1111940	hsa-miR-4672	CLIP-seq
MIRT1111941	hsa-miR-4694-3p	CLIP-seq
MIRT1111942	hsa-miR-4716-3p	CLIP-seq
MIRT1111943	hsa-miR-4797-3p	CLIP-seq
MIRT1111944	hsa-miR-522	CLIP-seq
MIRT1111945	hsa-miR-543	CLIP-seq
MIRT1111946	hsa-miR-545	CLIP-seq
MIRT1111947	hsa-miR-625	CLIP-seq
MIRT1111948	hsa-miR-761	CLIP-seq
MIRT1111949	hsa-miR-802	CLIP-seq
MIRT1111950	hsa-miR-922	CLIP-seq
MIRT1111951	hsa-miR-92a	CLIP-seq
MIRT1111952	hsa-miR-92b	CLIP-seq
MIRT2031238	hsa-miR-18a	CLIP-seq
MIRT2031239	hsa-miR-18b	CLIP-seq
MIRT1111919	hsa-miR-22	CLIP-seq
MIRT1111922	hsa-miR-302f	CLIP-seq
MIRT2031240	hsa-miR-3164	CLIP-seq
MIRT2031241	hsa-miR-3618	CLIP-seq
MIRT2031242	hsa-miR-3622b-5p	CLIP-seq
MIRT2031243	hsa-miR-3647-3p	CLIP-seq
MIRT2031244	hsa-miR-4487	CLIP-seq
MIRT2031245	hsa-miR-4633-3p	CLIP-seq
MIRT1111940	hsa-miR-4672	CLIP-seq
MIRT2031246	hsa-miR-4735-3p	CLIP-seq
MIRT2031247	hsa-miR-498	CLIP-seq
MIRT2031248	hsa-miR-520d-5p	CLIP-seq
MIRT2031249	hsa-miR-524-5p	CLIP-seq
MIRT2031250	hsa-miR-548q	CLIP-seq
MIRT1111915	hsa-miR-1197	CLIP-seq
MIRT2262027	hsa-miR-1206	CLIP-seq
MIRT2262028	hsa-miR-124	CLIP-seq
MIRT1111916	hsa-miR-1273e	CLIP-seq
MIRT2262029	hsa-miR-1273f	CLIP-seq
MIRT2262030	hsa-miR-1276	CLIP-seq
MIRT2262031	hsa-miR-1279	CLIP-seq
MIRT2262032	hsa-miR-1283	CLIP-seq
MIRT2262033	hsa-miR-1289	CLIP-seq
MIRT1111917	hsa-miR-1298	CLIP-seq
MIRT2262034	hsa-miR-134	CLIP-seq
MIRT2262035	hsa-miR-139-5p	CLIP-seq
MIRT2262036	hsa-miR-143	CLIP-seq
MIRT2262037	hsa-miR-146b-3p	CLIP-seq
MIRT2262038	hsa-miR-1470	CLIP-seq
MIRT2262039	hsa-miR-150	CLIP-seq
MIRT2262040	hsa-miR-1825	CLIP-seq
MIRT2262041	hsa-miR-186	CLIP-seq
MIRT2031238	hsa-miR-18a	CLIP-seq
MIRT2031239	hsa-miR-18b	CLIP-seq
MIRT2262042	hsa-miR-197	CLIP-seq
MIRT2262043	hsa-miR-200b	CLIP-seq
MIRT2262044	hsa-miR-200c	CLIP-seq
MIRT2262045	hsa-miR-2052	CLIP-seq
MIRT2262046	hsa-miR-2053	CLIP-seq
MIRT1111919	hsa-miR-22	CLIP-seq
MIRT2262047	hsa-miR-223	CLIP-seq
MIRT2262048	hsa-miR-2276	CLIP-seq
MIRT2262049	hsa-miR-2355-5p	CLIP-seq
MIRT1111921	hsa-miR-25	CLIP-seq
MIRT2262050	hsa-miR-300	CLIP-seq
MIRT1111922	hsa-miR-302f	CLIP-seq
MIRT2262051	hsa-miR-3074-3p	CLIP-seq
MIRT1111923	hsa-miR-3117-3p	CLIP-seq
MIRT2262052	hsa-miR-3118	CLIP-seq
MIRT2262053	hsa-miR-3121-3p	CLIP-seq
MIRT2262054	hsa-miR-3124-3p	CLIP-seq
MIRT2262055	hsa-miR-3132	CLIP-seq
MIRT2262056	hsa-miR-3133	CLIP-seq
MIRT2262057	hsa-miR-3138	CLIP-seq
MIRT1111925	hsa-miR-3143	CLIP-seq
MIRT2031240	hsa-miR-3164	CLIP-seq
MIRT2262058	hsa-miR-3165	CLIP-seq
MIRT2262059	hsa-miR-3173-5p	CLIP-seq
MIRT2262060	hsa-miR-3176	CLIP-seq
MIRT2262061	hsa-miR-3182	CLIP-seq
MIRT2262062	hsa-miR-3198	CLIP-seq
MIRT1111926	hsa-miR-3199	CLIP-seq
MIRT1111927	hsa-miR-32	CLIP-seq
MIRT2262063	hsa-miR-3200-5p	CLIP-seq
MIRT2262064	hsa-miR-3202	CLIP-seq
MIRT2262065	hsa-miR-320e	CLIP-seq
MIRT2262066	hsa-miR-338-5p	CLIP-seq
MIRT2262067	hsa-miR-34a	CLIP-seq
MIRT2262068	hsa-miR-34c-5p	CLIP-seq
MIRT2262069	hsa-miR-361-3p	CLIP-seq
MIRT2031241	hsa-miR-3618	CLIP-seq
MIRT2262070	hsa-miR-3622a-5p	CLIP-seq
MIRT2031242	hsa-miR-3622b-5p	CLIP-seq
MIRT1111930	hsa-miR-363	CLIP-seq
MIRT2262071	hsa-miR-3664-5p	CLIP-seq
MIRT1111931	hsa-miR-367	CLIP-seq
MIRT2262072	hsa-miR-371b-3p	CLIP-seq
MIRT2262073	hsa-miR-374c	CLIP-seq
MIRT2262074	hsa-miR-381	CLIP-seq
MIRT2262075	hsa-miR-3907	CLIP-seq
MIRT2262076	hsa-miR-3921	CLIP-seq
MIRT2262077	hsa-miR-3922-3p	CLIP-seq
MIRT2262078	hsa-miR-412	CLIP-seq
MIRT2262079	hsa-miR-4251	CLIP-seq
MIRT2262080	hsa-miR-4256	CLIP-seq
MIRT2262081	hsa-miR-4267	CLIP-seq
MIRT2262082	hsa-miR-4270	CLIP-seq
MIRT1111933	hsa-miR-4278	CLIP-seq
MIRT2262083	hsa-miR-429	CLIP-seq
MIRT1111934	hsa-miR-4291	CLIP-seq
MIRT2262084	hsa-miR-4294	CLIP-seq
MIRT2262085	hsa-miR-4299	CLIP-seq
MIRT2262086	hsa-miR-4309	CLIP-seq
MIRT2262087	hsa-miR-4310	CLIP-seq
MIRT1111935	hsa-miR-4325	CLIP-seq
MIRT2262088	hsa-miR-4328	CLIP-seq
MIRT2262089	hsa-miR-4329	CLIP-seq
MIRT2262090	hsa-miR-4330	CLIP-seq
MIRT2262091	hsa-miR-4422	CLIP-seq
MIRT2262092	hsa-miR-4435	CLIP-seq
MIRT2262093	hsa-miR-4441	CLIP-seq
MIRT1111937	hsa-miR-4446-5p	CLIP-seq
MIRT2031244	hsa-miR-4487	CLIP-seq
MIRT2262094	hsa-miR-4493	CLIP-seq
MIRT2262095	hsa-miR-449a	CLIP-seq
MIRT2262096	hsa-miR-449b	CLIP-seq
MIRT2262097	hsa-miR-450b-3p	CLIP-seq
MIRT2262098	hsa-miR-4515	CLIP-seq
MIRT2262099	hsa-miR-4521	CLIP-seq
MIRT2262100	hsa-miR-4522	CLIP-seq
MIRT2031245	hsa-miR-4633-3p	CLIP-seq
MIRT2262101	hsa-miR-4643	CLIP-seq
MIRT2262102	hsa-miR-4645-5p	CLIP-seq
MIRT2262103	hsa-miR-4650-3p	CLIP-seq
MIRT2262104	hsa-miR-4650-5p	CLIP-seq
MIRT2262105	hsa-miR-4653-5p	CLIP-seq
MIRT2262106	hsa-miR-4659a-3p	CLIP-seq
MIRT2262107	hsa-miR-4659b-3p	CLIP-seq
MIRT2262108	hsa-miR-4666-3p	CLIP-seq
MIRT1111939	hsa-miR-4666-5p	CLIP-seq
MIRT2262109	hsa-miR-4667-3p	CLIP-seq
MIRT1111940	hsa-miR-4672	CLIP-seq
MIRT2262110	hsa-miR-4673	CLIP-seq
MIRT2262111	hsa-miR-4677-3p	CLIP-seq
MIRT2262112	hsa-miR-4679	CLIP-seq
MIRT2262113	hsa-miR-4684-5p	CLIP-seq
MIRT2262114	hsa-miR-4695-3p	CLIP-seq
MIRT2262115	hsa-miR-4704-3p	CLIP-seq
MIRT2262116	hsa-miR-4708-5p	CLIP-seq
MIRT2262117	hsa-miR-4713-3p	CLIP-seq
MIRT2262118	hsa-miR-4713-5p	CLIP-seq
MIRT2262119	hsa-miR-4714-5p	CLIP-seq
MIRT1111942	hsa-miR-4716-3p	CLIP-seq
MIRT2262120	hsa-miR-4717-3p	CLIP-seq
MIRT2262121	hsa-miR-4719	CLIP-seq
MIRT2262122	hsa-miR-4724-5p	CLIP-seq
MIRT2262123	hsa-miR-4726-3p	CLIP-seq
MIRT2031246	hsa-miR-4735-3p	CLIP-seq
MIRT2262124	hsa-miR-4735-5p	CLIP-seq
MIRT2262125	hsa-miR-4744	CLIP-seq
MIRT2262126	hsa-miR-4747-5p	CLIP-seq
MIRT2262127	hsa-miR-4753-3p	CLIP-seq
MIRT2262128	hsa-miR-4755-5p	CLIP-seq
MIRT2262129	hsa-miR-4756-3p	CLIP-seq
MIRT2262130	hsa-miR-4760-3p	CLIP-seq
MIRT2262131	hsa-miR-4762-5p	CLIP-seq
MIRT2262132	hsa-miR-4763-5p	CLIP-seq
MIRT2262133	hsa-miR-4766-5p	CLIP-seq
MIRT2262134	hsa-miR-4770	CLIP-seq
MIRT2262135	hsa-miR-4772-3p	CLIP-seq
MIRT2262136	hsa-miR-4795-3p	CLIP-seq
MIRT1111943	hsa-miR-4797-3p	CLIP-seq
MIRT2262137	hsa-miR-4797-5p	CLIP-seq
MIRT2262138	hsa-miR-490-5p	CLIP-seq
MIRT2262139	hsa-miR-494	CLIP-seq
MIRT2262140	hsa-miR-499a-5p	CLIP-seq
MIRT2262141	hsa-miR-506	CLIP-seq
MIRT2262142	hsa-miR-513c	CLIP-seq
MIRT2262143	hsa-miR-514b-5p	CLIP-seq
MIRT2031248	hsa-miR-520d-5p	CLIP-seq
MIRT2031249	hsa-miR-524-5p	CLIP-seq
MIRT2262144	hsa-miR-532-3p	CLIP-seq
MIRT2262145	hsa-miR-544	CLIP-seq
MIRT1111946	hsa-miR-545	CLIP-seq
MIRT2262146	hsa-miR-548ag	CLIP-seq
MIRT2262147	hsa-miR-548ai	CLIP-seq
MIRT2031250	hsa-miR-548q	CLIP-seq
MIRT2262148	hsa-miR-569	CLIP-seq
MIRT2262149	hsa-miR-570	CLIP-seq
MIRT2262150	hsa-miR-595	CLIP-seq
MIRT2262151	hsa-miR-621	CLIP-seq
MIRT1111947	hsa-miR-625	CLIP-seq
MIRT2262152	hsa-miR-638	CLIP-seq
MIRT2262153	hsa-miR-642a	CLIP-seq
MIRT2262154	hsa-miR-642b	CLIP-seq
MIRT2262155	hsa-miR-655	CLIP-seq
MIRT2262156	hsa-miR-656	CLIP-seq
MIRT2262157	hsa-miR-758	CLIP-seq
MIRT2262158	hsa-miR-769-3p	CLIP-seq
MIRT2262159	hsa-miR-874	CLIP-seq
MIRT1111951	hsa-miR-92a	CLIP-seq
MIRT1111952	hsa-miR-92b	CLIP-seq
MIRT2262160	hsa-miR-934	CLIP-seq
MIRT2262027	hsa-miR-1206	CLIP-seq
MIRT2561857	hsa-miR-1255a	CLIP-seq
MIRT2561858	hsa-miR-1255b	CLIP-seq
MIRT2262030	hsa-miR-1276	CLIP-seq
MIRT2262032	hsa-miR-1283	CLIP-seq
MIRT2262037	hsa-miR-146b-3p	CLIP-seq
MIRT2262040	hsa-miR-1825	CLIP-seq
MIRT2262045	hsa-miR-2052	CLIP-seq
MIRT2262046	hsa-miR-2053	CLIP-seq
MIRT2262047	hsa-miR-223	CLIP-seq
MIRT2262050	hsa-miR-300	CLIP-seq
MIRT2262053	hsa-miR-3121-3p	CLIP-seq
MIRT2262054	hsa-miR-3124-3p	CLIP-seq
MIRT2262055	hsa-miR-3132	CLIP-seq
MIRT2031240	hsa-miR-3164	CLIP-seq
MIRT2262059	hsa-miR-3173-5p	CLIP-seq
MIRT2262060	hsa-miR-3176	CLIP-seq
MIRT2262066	hsa-miR-338-5p	CLIP-seq
MIRT2031241	hsa-miR-3618	CLIP-seq
MIRT2031243	hsa-miR-3647-3p	CLIP-seq
MIRT2561859	hsa-miR-3689a-5p	CLIP-seq
MIRT2561860	hsa-miR-3689b	CLIP-seq
MIRT2561861	hsa-miR-3689e	CLIP-seq
MIRT2561862	hsa-miR-3689f	CLIP-seq
MIRT2262072	hsa-miR-371b-3p	CLIP-seq
MIRT2561863	hsa-miR-376a	CLIP-seq
MIRT2561864	hsa-miR-376b	CLIP-seq
MIRT2262074	hsa-miR-381	CLIP-seq
MIRT2262075	hsa-miR-3907	CLIP-seq
MIRT2262077	hsa-miR-3922-3p	CLIP-seq
MIRT2561865	hsa-miR-4282	CLIP-seq
MIRT2262088	hsa-miR-4328	CLIP-seq
MIRT2262092	hsa-miR-4435	CLIP-seq
MIRT2262103	hsa-miR-4650-3p	CLIP-seq
MIRT2262108	hsa-miR-4666-3p	CLIP-seq
MIRT1111939	hsa-miR-4666-5p	CLIP-seq
MIRT2262121	hsa-miR-4719	CLIP-seq
MIRT2262122	hsa-miR-4724-5p	CLIP-seq
MIRT2262127	hsa-miR-4753-3p	CLIP-seq
MIRT2262129	hsa-miR-4756-3p	CLIP-seq
MIRT2262137	hsa-miR-4797-5p	CLIP-seq
MIRT2561866	hsa-miR-488	CLIP-seq
MIRT2262139	hsa-miR-494	CLIP-seq
MIRT2031248	hsa-miR-520d-5p	CLIP-seq
MIRT2031249	hsa-miR-524-5p	CLIP-seq
MIRT2262146	hsa-miR-548ag	CLIP-seq
MIRT2262147	hsa-miR-548ai	CLIP-seq
MIRT2031250	hsa-miR-548q	CLIP-seq
MIRT2262148	hsa-miR-569	CLIP-seq
MIRT2262150	hsa-miR-595	CLIP-seq
MIRT2262151	hsa-miR-621	CLIP-seq
MIRT2262157	hsa-miR-758	CLIP-seq
MIRT2262159	hsa-miR-874	CLIP-seq
MIRT2262160	hsa-miR-934	CLIP-seq
MIRT2561857	hsa-miR-1255a	CLIP-seq
MIRT2561858	hsa-miR-1255b	CLIP-seq
MIRT2262030	hsa-miR-1276	CLIP-seq
MIRT2262032	hsa-miR-1283	CLIP-seq
MIRT2262037	hsa-miR-146b-3p	CLIP-seq
MIRT2262040	hsa-miR-1825	CLIP-seq
MIRT2262041	hsa-miR-186	CLIP-seq
MIRT2031238	hsa-miR-18a	CLIP-seq
MIRT2031239	hsa-miR-18b	CLIP-seq
MIRT2262046	hsa-miR-2053	CLIP-seq
MIRT2262050	hsa-miR-300	CLIP-seq
MIRT2262053	hsa-miR-3121-3p	CLIP-seq
MIRT2262054	hsa-miR-3124-3p	CLIP-seq
MIRT2262055	hsa-miR-3132	CLIP-seq
MIRT2262056	hsa-miR-3133	CLIP-seq
MIRT2031240	hsa-miR-3164	CLIP-seq
MIRT2262059	hsa-miR-3173-5p	CLIP-seq
MIRT2262060	hsa-miR-3176	CLIP-seq
MIRT2262066	hsa-miR-338-5p	CLIP-seq
MIRT2031241	hsa-miR-3618	CLIP-seq
MIRT2561859	hsa-miR-3689a-5p	CLIP-seq
MIRT2561860	hsa-miR-3689b	CLIP-seq
MIRT2561861	hsa-miR-3689e	CLIP-seq
MIRT2561862	hsa-miR-3689f	CLIP-seq
MIRT2262072	hsa-miR-371b-3p	CLIP-seq
MIRT2262074	hsa-miR-381	CLIP-seq
MIRT2262075	hsa-miR-3907	CLIP-seq
MIRT2262077	hsa-miR-3922-3p	CLIP-seq
MIRT2262092	hsa-miR-4435	CLIP-seq
MIRT2262103	hsa-miR-4650-3p	CLIP-seq
MIRT2262108	hsa-miR-4666-3p	CLIP-seq
MIRT1111939	hsa-miR-4666-5p	CLIP-seq
MIRT2262121	hsa-miR-4719	CLIP-seq
MIRT2031246	hsa-miR-4735-3p	CLIP-seq
MIRT2262125	hsa-miR-4744	CLIP-seq
MIRT2262127	hsa-miR-4753-3p	CLIP-seq
MIRT2262129	hsa-miR-4756-3p	CLIP-seq
MIRT2262137	hsa-miR-4797-5p	CLIP-seq
MIRT2561866	hsa-miR-488	CLIP-seq
MIRT2262139	hsa-miR-494	CLIP-seq
MIRT2031248	hsa-miR-520d-5p	CLIP-seq
MIRT2031249	hsa-miR-524-5p	CLIP-seq
MIRT2262146	hsa-miR-548ag	CLIP-seq
MIRT2262147	hsa-miR-548ai	CLIP-seq
MIRT2031250	hsa-miR-548q	CLIP-seq
MIRT2262148	hsa-miR-569	CLIP-seq
MIRT2262150	hsa-miR-595	CLIP-seq
MIRT2262151	hsa-miR-621	CLIP-seq
MIRT2262157	hsa-miR-758	CLIP-seq
MIRT2262159	hsa-miR-874	CLIP-seq
MIRT2262160	hsa-miR-934	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
SP1	Unknown	23291272

Show/Hide all (32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0001843	Process	Neural tube closure	IEA
GO:0001843	Process	Neural tube closure	ISS
GO:0003281	Process	Ventricular septum development	IEA
GO:0003712	Function	Transcription coregulator activity	IEA
GO:0003714	Function	Transcription corepressor activity	IEA
GO:0005515	Function	Protein binding	IPI	15231748, 18330356, 20211142, 25416956, 25502805, 30886144, 31515488, 32296183, 35914814
GO:0005634	Component	Nucleus	IEA
GO:0005667	Component	Transcription regulator complex	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0008045	Process	Motor neuron axon guidance	IEA
GO:0009888	Process	Tissue development	IEA
GO:0021514	Process	Ventral spinal cord interneuron differentiation	IEA
GO:0021520	Process	Spinal cord motor neuron cell fate specification	IEA
GO:0021522	Process	Spinal cord motor neuron differentiation	IEA
GO:0021527	Process	Spinal cord association neuron differentiation	IEA
GO:0030334	Process	Regulation of cell migration	IEA
GO:0030334	Process	Regulation of cell migration	ISS
GO:0031252	Component	Cell leading edge	IEA
GO:0031252	Component	Cell leading edge	ISS
GO:0031333	Process	Negative regulation of protein-containing complex assembly	IEA
GO:0033674	Process	Positive regulation of kinase activity	ISS
GO:0042659	Process	Regulation of cell fate specification	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048538	Process	Thymus development	IEA
GO:0050793	Process	Regulation of developmental process	IEA
GO:0050865	Process	Regulation of cell activation	IEA
GO:0090575	Component	RNA polymerase II transcription regulator complex	IEA
GO:0140297	Function	DNA-binding transcription factor binding	IEA
GO:0140297	Function	DNA-binding transcription factor binding	ISS

MIM	HGNC	e!Ensembl
603129	6644	ENSG00000143013

P61968

Protein name

LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4)

Protein function

Transcription cofactor. Plays a role in establishing motor neuron identity, in concert with MNX1, acting, at least in part, to disrupt LDB1-LHX3 complexes thereby negatively modulating interneuron genes in motor neurons. {ECO:0000250|UniProtKB:P

PDB

9F5B

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00412	LIM	23 → 81	LIM domain	Domain
PF00412	LIM	87 → 143	LIM domain	Domain

Sequence

MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC

Sequence length

165

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ANKYLOSING SPONDYLITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BREAST CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (38)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Anaplasia	Anaplasia	BEFREE	12771919		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Cancer, Familial	Breast Cancer	BEFREE	16280053		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11734645, 12906853, 12925972, 15897450, 15930276, 16288053, 16331278, 17452977, 19648968, 20814902, 22906635, 23291272, 23353824, 23407556, 27354352, 31215771 View all (1 more)		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	11751867	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19099607, 20814902, 21909792, 27354352, 31215771	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt`s Lymphoma	BEFREE	30422313		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	19099607	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	Pubtator	20814902	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	18231110	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	12771919, 33906487	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic retinopathy	Pubtator	34725544	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Epithelioma	Epithelioma	BEFREE	19648968		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	19099607	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intraepithelial Neoplasia	Intraepithelial Neoplasia	BEFREE	15897450		★★★★★ ★☆☆☆☆ Found in Text Mining only
Invasive Ductal Breast Carcinoma	Invasive Duct and Lobular Carcinoma	BEFREE	19099607		★★★★★ ★☆☆☆☆ Found in Text Mining only
Macular dystrophy retinal 1 North Carolina type	Macular dystrophy	Pubtator	34725544	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11734645, 12906853, 12925972, 15897450, 15930276, 16288053, 16331278, 17452977, 19648968, 20814902, 22906635, 23291272, 23353824, 23407556, 27354352, 31215771 View all (1 more)		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	19099607		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	31737204		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	12906853, 21124317		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	BEFREE	22964784		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	11888886, 15897450, 23353824, 23407556, 29736306		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	12877980, 23407937		★★★★★ ★☆☆☆☆ Found in Text Mining only
NEUROTICISM	Neuroticism	BEFREE	25994864		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	25613065	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	19099607		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasm	Pancreatic Neoplasm	LHGDN	19099607		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	19099607	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Papillary thyroid carcinoma	Papillary thyroid carcinoma	BEFREE	30796202		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Pituitary neoplasm	Pubtator	30609812	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	Lymphoblastic Leukemia	BEFREE	11734645		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	29258893		★★★★★ ★☆☆☆☆ Found in Text Mining only
Rhabdomyosarcoma	Rhabdomyosarcoma	BEFREE	21271214		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	12771919		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	12771919	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	31737204		★★★★★ ★☆☆☆☆ Found in Text Mining only
T-Cell Lymphoma	T-Cell Lymphoma	BEFREE	29258893		★★★★★ ★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Triple negative breast cancer	Pubtator	36077333	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

LMO4 (LIM domain only 4)