HAT1 (histone acetyltransferase 1)

Gene

• Entrez ID: 8520
• Gene name: Histone acetyltransferase 1
• Gene symbol: HAT1
• Synonyms (NCBI Gene): KAT1
• Chromosome: 2
• Chromosome location: 2q31.1
• Summary: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. H

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028253	hsa-miR-32-5p	Sequencing	20371350
MIRT498997	hsa-miR-3133	PAR-CLIP	20371350
MIRT498995	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT498994	hsa-miR-1243	PAR-CLIP	20371350
MIRT498993	hsa-miR-4463	PAR-CLIP	20371350
MIRT498992	hsa-miR-4494	PAR-CLIP	20371350
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	20371350
MIRT498990	hsa-miR-1261	PAR-CLIP	20371350
MIRT498997	hsa-miR-3133	PAR-CLIP	21572407
MIRT498995	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT498994	hsa-miR-1243	PAR-CLIP	21572407
MIRT498993	hsa-miR-4463	PAR-CLIP	21572407
MIRT498992	hsa-miR-4494	PAR-CLIP	21572407
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	21572407
MIRT498990	hsa-miR-1261	PAR-CLIP	21572407
MIRT498997	hsa-miR-3133	PAR-CLIP	22012620
MIRT498995	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT527666	hsa-miR-8485	PAR-CLIP	22012620
MIRT527665	hsa-miR-329-3p	PAR-CLIP	22012620
MIRT527664	hsa-miR-362-3p	PAR-CLIP	22012620
MIRT527663	hsa-miR-603	PAR-CLIP	22012620
MIRT498994	hsa-miR-1243	PAR-CLIP	22012620
MIRT498993	hsa-miR-4463	PAR-CLIP	22012620
MIRT498992	hsa-miR-4494	PAR-CLIP	22012620
MIRT527662	hsa-miR-5190	PAR-CLIP	22012620
MIRT523319	hsa-miR-542-3p	PAR-CLIP	22012620
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	22012620
MIRT527661	hsa-miR-3941	PAR-CLIP	22012620
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	22012620
MIRT498990	hsa-miR-1261	PAR-CLIP	22012620
MIRT498997	hsa-miR-3133	PAR-CLIP	23446348
MIRT498995	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT498994	hsa-miR-1243	PAR-CLIP	23446348
MIRT498993	hsa-miR-4463	PAR-CLIP	23446348
MIRT498992	hsa-miR-4494	PAR-CLIP	23446348
MIRT523319	hsa-miR-542-3p	PAR-CLIP	23446348
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	23446348
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT498990	hsa-miR-1261	PAR-CLIP	23446348
MIRT498997	hsa-miR-3133	PAR-CLIP	23446348
MIRT498995	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT498994	hsa-miR-1243	PAR-CLIP	23446348
MIRT498993	hsa-miR-4463	PAR-CLIP	23446348
MIRT498992	hsa-miR-4494	PAR-CLIP	23446348
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	23446348
MIRT498990	hsa-miR-1261	PAR-CLIP	23446348
MIRT498997	hsa-miR-3133	PAR-CLIP	24398324
MIRT498995	hsa-miR-186-5p	PAR-CLIP	24398324
MIRT498994	hsa-miR-1243	PAR-CLIP	24398324
MIRT498993	hsa-miR-4463	PAR-CLIP	24398324
MIRT498992	hsa-miR-4494	PAR-CLIP	24398324
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	24398324
MIRT498990	hsa-miR-1261	PAR-CLIP	24398324
MIRT475853	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT475852	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT299418	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT475851	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT475850	hsa-let-7c-3p	PAR-CLIP	23592263
MIRT475849	hsa-let-7a-2-3p	PAR-CLIP	23592263
MIRT475848	hsa-let-7g-3p	PAR-CLIP	23592263
MIRT475847	hsa-miR-493-5p	PAR-CLIP	23592263
MIRT475846	hsa-miR-5096	PAR-CLIP	23592263
MIRT475845	hsa-miR-335-3p	PAR-CLIP	23592263
MIRT449473	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT449472	hsa-miR-300	PAR-CLIP	22100165
MIRT449471	hsa-miR-381-3p	PAR-CLIP	22100165
MIRT449470	hsa-miR-4666a-3p	PAR-CLIP	22100165
MIRT449469	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT449467	hsa-miR-4635	PAR-CLIP	22100165
MIRT449468	hsa-let-7a-3p	PAR-CLIP	22100165
MIRT449466	hsa-let-7b-3p	PAR-CLIP	22100165
MIRT449465	hsa-let-7f-1-3p	PAR-CLIP	22100165
MIRT449464	hsa-miR-98-3p	PAR-CLIP	22100165
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	22100165
MIRT449462	hsa-let-7f-2-3p	PAR-CLIP	22100165
MIRT449461	hsa-miR-1185-1-3p	PAR-CLIP	22100165
MIRT449460	hsa-miR-1185-2-3p	PAR-CLIP	22100165
MIRT449459	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT733470	hsa-miR-486-5p	qRT-PCR	26654953
MIRT733470	hsa-miR-486-5p	RNA-seq	34199766
MIRT733470	hsa-miR-486-5p	ELISA, In situ hybridization, Luciferase reporter assay, Microarray, qRT-PCR, Western blotting	33244226
MIRT498997	hsa-miR-3133	PAR-CLIP	20371350
MIRT498995	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT498994	hsa-miR-1243	PAR-CLIP	20371350
MIRT498993	hsa-miR-4463	PAR-CLIP	20371350
MIRT498992	hsa-miR-4494	PAR-CLIP	20371350
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	20371350
MIRT498990	hsa-miR-1261	PAR-CLIP	20371350
MIRT498997	hsa-miR-3133	PAR-CLIP	21572407
MIRT498995	hsa-miR-186-5p	PAR-CLIP	21572407
MIRT498994	hsa-miR-1243	PAR-CLIP	21572407
MIRT498993	hsa-miR-4463	PAR-CLIP	21572407
MIRT498992	hsa-miR-4494	PAR-CLIP	21572407
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	21572407
MIRT498990	hsa-miR-1261	PAR-CLIP	21572407
MIRT498997	hsa-miR-3133	PAR-CLIP	22012620
MIRT498995	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT527666	hsa-miR-8485	PAR-CLIP	22012620
MIRT527665	hsa-miR-329-3p	PAR-CLIP	22012620
MIRT527664	hsa-miR-362-3p	PAR-CLIP	22012620
MIRT527663	hsa-miR-603	PAR-CLIP	22012620
MIRT498994	hsa-miR-1243	PAR-CLIP	22012620
MIRT498993	hsa-miR-4463	PAR-CLIP	22012620
MIRT498992	hsa-miR-4494	PAR-CLIP	22012620
MIRT527662	hsa-miR-5190	PAR-CLIP	22012620
MIRT523319	hsa-miR-542-3p	PAR-CLIP	22012620
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	22012620
MIRT527661	hsa-miR-3941	PAR-CLIP	22012620
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	22012620
MIRT498990	hsa-miR-1261	PAR-CLIP	22012620
MIRT498997	hsa-miR-3133	PAR-CLIP	23446348
MIRT498995	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT498994	hsa-miR-1243	PAR-CLIP	23446348
MIRT498993	hsa-miR-4463	PAR-CLIP	23446348
MIRT498992	hsa-miR-4494	PAR-CLIP	23446348
MIRT523319	hsa-miR-542-3p	PAR-CLIP	23446348
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	23446348
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	23446348
MIRT498990	hsa-miR-1261	PAR-CLIP	23446348
MIRT498997	hsa-miR-3133	PAR-CLIP	23446348
MIRT498995	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT498994	hsa-miR-1243	PAR-CLIP	23446348
MIRT498993	hsa-miR-4463	PAR-CLIP	23446348
MIRT498992	hsa-miR-4494	PAR-CLIP	23446348
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	23446348
MIRT498990	hsa-miR-1261	PAR-CLIP	23446348
MIRT498997	hsa-miR-3133	PAR-CLIP	24398324
MIRT498995	hsa-miR-186-5p	PAR-CLIP	24398324
MIRT498994	hsa-miR-1243	PAR-CLIP	24398324
MIRT498993	hsa-miR-4463	PAR-CLIP	24398324
MIRT498992	hsa-miR-4494	PAR-CLIP	24398324
MIRT498991	hsa-miR-4536-5p	PAR-CLIP	24398324
MIRT498990	hsa-miR-1261	PAR-CLIP	24398324
MIRT475853	hsa-miR-27a-3p	PAR-CLIP	23592263
MIRT475852	hsa-miR-27b-3p	PAR-CLIP	23592263
MIRT299418	hsa-miR-10b-3p	PAR-CLIP	23592263
MIRT475851	hsa-miR-513a-5p	PAR-CLIP	23592263
MIRT475850	hsa-let-7c-3p	PAR-CLIP	23592263
MIRT475849	hsa-let-7a-2-3p	PAR-CLIP	23592263
MIRT475848	hsa-let-7g-3p	PAR-CLIP	23592263
MIRT475847	hsa-miR-493-5p	PAR-CLIP	23592263
MIRT475846	hsa-miR-5096	PAR-CLIP	23592263
MIRT475845	hsa-miR-335-3p	PAR-CLIP	23592263
MIRT449473	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT449472	hsa-miR-300	PAR-CLIP	22100165
MIRT449471	hsa-miR-381-3p	PAR-CLIP	22100165
MIRT449470	hsa-miR-4666a-3p	PAR-CLIP	22100165
MIRT449469	hsa-miR-3613-3p	PAR-CLIP	22100165
MIRT449467	hsa-miR-4635	PAR-CLIP	22100165
MIRT449468	hsa-let-7a-3p	PAR-CLIP	22100165
MIRT449466	hsa-let-7b-3p	PAR-CLIP	22100165
MIRT449465	hsa-let-7f-1-3p	PAR-CLIP	22100165
MIRT449464	hsa-miR-98-3p	PAR-CLIP	22100165
MIRT449463	hsa-miR-4789-5p	PAR-CLIP	22100165
MIRT449462	hsa-let-7f-2-3p	PAR-CLIP	22100165
MIRT449461	hsa-miR-1185-1-3p	PAR-CLIP	22100165
MIRT449460	hsa-miR-1185-2-3p	PAR-CLIP	22100165
MIRT449459	hsa-miR-488-3p	PAR-CLIP	22100165
MIRT1040988	hsa-miR-144	CLIP-seq
MIRT1040989	hsa-miR-216b	CLIP-seq
MIRT1040990	hsa-miR-381	CLIP-seq
MIRT1040991	hsa-miR-4666-3p	CLIP-seq
MIRT1040992	hsa-miR-618	CLIP-seq
MIRT2008572	hsa-miR-4282	CLIP-seq
MIRT2008573	hsa-miR-4457	CLIP-seq
MIRT2008574	hsa-miR-4698	CLIP-seq
MIRT2008575	hsa-miR-513b	CLIP-seq
MIRT2008576	hsa-miR-548p	CLIP-seq
MIRT2241011	hsa-miR-199a-3p	CLIP-seq
MIRT2241012	hsa-miR-199b-3p	CLIP-seq
MIRT2241013	hsa-miR-27a	CLIP-seq
MIRT2241014	hsa-miR-27b	CLIP-seq
MIRT2241015	hsa-miR-3129-5p	CLIP-seq
MIRT2241016	hsa-miR-3942-3p	CLIP-seq
MIRT2544574	hsa-miR-2278	CLIP-seq
MIRT2241013	hsa-miR-27a	CLIP-seq
MIRT2241014	hsa-miR-27b	CLIP-seq
MIRT2544575	hsa-miR-3647-3p	CLIP-seq
MIRT2008572	hsa-miR-4282	CLIP-seq
MIRT2008573	hsa-miR-4457	CLIP-seq
MIRT2544576	hsa-miR-450b-5p	CLIP-seq
MIRT2544577	hsa-miR-4797-5p	CLIP-seq
MIRT2008575	hsa-miR-513b	CLIP-seq
MIRT2544578	hsa-miR-516a-3p	CLIP-seq
MIRT2544574	hsa-miR-2278	CLIP-seq
MIRT2241013	hsa-miR-27a	CLIP-seq
MIRT2241014	hsa-miR-27b	CLIP-seq
MIRT2544575	hsa-miR-3647-3p	CLIP-seq
MIRT2008572	hsa-miR-4282	CLIP-seq
MIRT2008573	hsa-miR-4457	CLIP-seq
MIRT2544576	hsa-miR-450b-5p	CLIP-seq
MIRT2544577	hsa-miR-4797-5p	CLIP-seq
MIRT2008575	hsa-miR-513b	CLIP-seq
MIRT2544578	hsa-miR-516a-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000781	Component	Chromosome, telomeric region	HDA	19135898
GO:0000785	Component	Chromatin	IDA	14718166
GO:0004402	Function	Histone acetyltransferase activity	IEA
GO:0004402	Function	Histone acetyltransferase activity	TAS	9427644
GO:0005515	Function	Protein binding	IPI	19862764, 22190034, 22615379, 24981860, 25416956, 32296183, 33961781
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	9427644
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006334	Process	Nucleosome assembly	IDA	14718166
GO:0006475	Process	Internal protein amino acid acetylation	TAS	9427644
GO:0010485	Function	Histone H4 acetyltransferase activity	IBA
GO:0016363	Component	Nuclear matrix	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0031509	Process	Subtelomeric heterochromatin formation	IEA
GO:0032991	Component	Protein-containing complex	IDA	14718166
GO:0042393	Function	Histone binding	IEA
GO:0043997	Function	Histone H4K12 acetyltransferase activity	IDA	22615379
GO:0051276	Process	Chromosome organization	TAS	9427644
GO:0061733	Function	Protein-lysine-acetyltransferase activity	IEA

Other IDs

• MIM: 603053
• HGNC: 4821
• e!Ensembl: ENSG00000128708

Protein

• UniProt ID: O14929
• Protein name: Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)
• Protein function: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair (PubMed:20953179, PubMed:23653357, PubMed:31278053, PubMed:32081014). Coo
• PDB: 2P0W, 6VO5, 9MJG
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10394	Hat1_N	25 → 187	Histone acetyl transferase HAT1 N-terminus	Domain

• Sequence:

  MAGFGAMEKFLVEYKSAVEKKLAEYKCNTNTAIELKLVRFPEDLENDIRTFFPEYTHQLF
  GDDETAFGYKGLKILLYYIAGSLSTMFRVEYASKVDENFDCVEADDVEGKIRQIIPPGFC
  TNTNDFLSLLEKEVDFKPFGTLLHTYSVLSPTGGENFTFQIYKADMTCRGFREYHERLQT
  FLMWFIETASFIDVDDERWHYFLVFEKYNKDGATLFATVGYMTVYNYYVYPDKTRPRVSQ
  MLILTPFQGQGHGAQLLETVHRYYTEFPTVLDITAEDPSKSYVKLRDFVLVKLCQDLPCF
  SREKLMQGFNEDMAIEAQQKFKINKQHARRVYEILRLLVTDMSDAEQYRSYRLDIKRRLI
  SPYKKKQRDLAKMRKCLRPEELTNQMNQIEISMQHEQLEESFQELVEDYRRVIERLAQE

• Sequence length: 419

Pathways

KEGG:

Neutrophil extracellular trap formation
Alcoholism

Reactome:

HATs acetylate histones

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	30709380		★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	31565149		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	31565149		★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	Pubtator	31565149	Associate	★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	25358520		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	12841681	Associate	★☆☆☆☆ Found in Text Mining only
Cancer of Nasopharynx	Nasopharyngeal Cancer	BEFREE	29621521		★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	33372411	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33372411	Stimulate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	37763801	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	29163803		★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Cholangiocarcinoma	Pubtator	33372411	Stimulate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	31666808		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	29777939		★☆☆☆☆ Found in Text Mining only
Esophageal carcinoma	Esophageal Carcinoma	BEFREE	25120766		★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Esophageal neoplasm	Pubtator	25120766	Associate	★☆☆☆☆ Found in Text Mining only
Esophageal Squamous Cell Carcinoma	Esophageal squamous cell carcinoma	Pubtator	25120766	Associate	★☆☆☆☆ Found in Text Mining only
Hyperlipidemia	Hyperlipidemia	BEFREE	30784937		★☆☆☆☆ Found in Text Mining only
Hypoxia	Hypoxia	Pubtator	30385847	Associate	★☆☆☆☆ Found in Text Mining only
Immunologic Deficiency Syndromes	Immunologic Deficiency Syndromes	BEFREE	29615725		★☆☆☆☆ Found in Text Mining only
Inflammatory Bowel Diseases	Inflammatory Bowel Disease	BEFREE	31666808		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	27938492		★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	22683764		★☆☆☆☆ Found in Text Mining only
Malignant melanoma of choroid	Choroidal melanoma	BEFREE	28706436		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	25358520		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	29163803		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of nasopharynx	Nasopharyngeal carcinoma	BEFREE	29621521		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	30709380		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29535128, 30709380		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	29777939		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	29621521		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	25120766, 30709380, 31152456		★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	30385847	Inhibit	★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	Pubtator	30385847	Inhibit	★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	30942624, 31152456		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	30942624	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	30709380		★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	33372411	Stimulate	★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	BEFREE	31419323		★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	33244226	Associate	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	GWASCAT_DG	31374203		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	25120766		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of lip	Carcinoma of Lip	BEFREE	28107582		★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	31666808		★☆☆☆☆ Found in Text Mining only