Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84922
Gene name	FLT3 interacting zinc finger 1
Gene symbol	FIZ1
Synonyms (NCBI Gene)	ZNF798
Chromosome	19
Chromosome location	19q13.42
Summary	This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specif

146

Show/Hide all (146)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018416	hsa-miR-335-5p	Microarray	18185580
MIRT021131	hsa-miR-186-5p	Sequencing	20371350
MIRT028700	hsa-miR-27a-3p	Sequencing	20371350
MIRT041828	hsa-miR-484	CLASH	23622248
MIRT462477	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT462476	hsa-miR-3065-3p	PAR-CLIP	23592263
MIRT462475	hsa-miR-383-3p	PAR-CLIP	23592263
MIRT462474	hsa-miR-130b-5p	PAR-CLIP	23592263
MIRT462473	hsa-miR-3153	PAR-CLIP	23592263
MIRT462472	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT462471	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT462470	hsa-miR-6716-5p	PAR-CLIP	23592263
MIRT462469	hsa-miR-4291	PAR-CLIP	23592263
MIRT462477	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT462476	hsa-miR-3065-3p	PAR-CLIP	23592263
MIRT462475	hsa-miR-383-3p	PAR-CLIP	23592263
MIRT462474	hsa-miR-130b-5p	PAR-CLIP	23592263
MIRT462473	hsa-miR-3153	PAR-CLIP	23592263
MIRT462472	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT462471	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT462470	hsa-miR-6716-5p	PAR-CLIP	23592263
MIRT462469	hsa-miR-4291	PAR-CLIP	23592263
MIRT996960	hsa-miR-1207-5p	CLIP-seq
MIRT996961	hsa-miR-122	CLIP-seq
MIRT996962	hsa-miR-1252	CLIP-seq
MIRT996963	hsa-miR-1273f	CLIP-seq
MIRT996964	hsa-miR-1275	CLIP-seq
MIRT996965	hsa-miR-1285	CLIP-seq
MIRT996966	hsa-miR-1293	CLIP-seq
MIRT996967	hsa-miR-141	CLIP-seq
MIRT996968	hsa-miR-1470	CLIP-seq
MIRT996969	hsa-miR-185	CLIP-seq
MIRT996970	hsa-miR-1908	CLIP-seq
MIRT996971	hsa-miR-1910	CLIP-seq
MIRT996972	hsa-miR-1972	CLIP-seq
MIRT996973	hsa-miR-199a-5p	CLIP-seq
MIRT996974	hsa-miR-199b-5p	CLIP-seq
MIRT996975	hsa-miR-200a	CLIP-seq
MIRT996976	hsa-miR-3126-5p	CLIP-seq
MIRT996977	hsa-miR-3127-5p	CLIP-seq
MIRT996978	hsa-miR-3150a-3p	CLIP-seq
MIRT996979	hsa-miR-3167	CLIP-seq
MIRT996980	hsa-miR-3175	CLIP-seq
MIRT996981	hsa-miR-3180	CLIP-seq
MIRT996982	hsa-miR-3180-3p	CLIP-seq
MIRT996983	hsa-miR-3187-5p	CLIP-seq
MIRT996984	hsa-miR-3196	CLIP-seq
MIRT996985	hsa-miR-3607-5p	CLIP-seq
MIRT996986	hsa-miR-3616-3p	CLIP-seq
MIRT996987	hsa-miR-3647-3p	CLIP-seq
MIRT996988	hsa-miR-3650	CLIP-seq
MIRT996989	hsa-miR-3690	CLIP-seq
MIRT996990	hsa-miR-376c	CLIP-seq
MIRT996991	hsa-miR-3925-3p	CLIP-seq
MIRT996992	hsa-miR-4254	CLIP-seq
MIRT996993	hsa-miR-4255	CLIP-seq
MIRT996994	hsa-miR-4260	CLIP-seq
MIRT996995	hsa-miR-4261	CLIP-seq
MIRT996996	hsa-miR-4270	CLIP-seq
MIRT996997	hsa-miR-4271	CLIP-seq
MIRT996998	hsa-miR-4306	CLIP-seq
MIRT996999	hsa-miR-4436a	CLIP-seq
MIRT997000	hsa-miR-4436b-3p	CLIP-seq
MIRT997001	hsa-miR-4441	CLIP-seq
MIRT997002	hsa-miR-4443	CLIP-seq
MIRT997003	hsa-miR-4450	CLIP-seq
MIRT997004	hsa-miR-4455	CLIP-seq
MIRT997005	hsa-miR-4469	CLIP-seq
MIRT997006	hsa-miR-4483	CLIP-seq
MIRT997007	hsa-miR-4496	CLIP-seq
MIRT997008	hsa-miR-4533	CLIP-seq
MIRT997009	hsa-miR-4534	CLIP-seq
MIRT997010	hsa-miR-455-3p	CLIP-seq
MIRT997011	hsa-miR-4639-3p	CLIP-seq
MIRT997012	hsa-miR-4644	CLIP-seq
MIRT997013	hsa-miR-4650-5p	CLIP-seq
MIRT997014	hsa-miR-4665-5p	CLIP-seq
MIRT997015	hsa-miR-4667-3p	CLIP-seq
MIRT997016	hsa-miR-4667-5p	CLIP-seq
MIRT997017	hsa-miR-4669	CLIP-seq
MIRT997018	hsa-miR-4690-3p	CLIP-seq
MIRT997019	hsa-miR-4700-3p	CLIP-seq
MIRT997020	hsa-miR-4700-5p	CLIP-seq
MIRT997021	hsa-miR-4706	CLIP-seq
MIRT997022	hsa-miR-4716-5p	CLIP-seq
MIRT997023	hsa-miR-4725-3p	CLIP-seq
MIRT997024	hsa-miR-4747-5p	CLIP-seq
MIRT997025	hsa-miR-4749-5p	CLIP-seq
MIRT997026	hsa-miR-4756-3p	CLIP-seq
MIRT997027	hsa-miR-4761-5p	CLIP-seq
MIRT997028	hsa-miR-4763-3p	CLIP-seq
MIRT997029	hsa-miR-515-5p	CLIP-seq
MIRT997030	hsa-miR-612	CLIP-seq
MIRT997031	hsa-miR-615-5p	CLIP-seq
MIRT997032	hsa-miR-624	CLIP-seq
MIRT997033	hsa-miR-663	CLIP-seq
MIRT997034	hsa-miR-766	CLIP-seq
MIRT997035	hsa-miR-875-3p	CLIP-seq
MIRT997036	hsa-miR-876-5p	CLIP-seq
MIRT997037	hsa-miR-939	CLIP-seq
MIRT1995628	hsa-miR-1226	CLIP-seq
MIRT1995629	hsa-miR-1245b-3p	CLIP-seq
MIRT996973	hsa-miR-199a-5p	CLIP-seq
MIRT996974	hsa-miR-199b-5p	CLIP-seq
MIRT1995630	hsa-miR-27a	CLIP-seq
MIRT1995631	hsa-miR-27b	CLIP-seq
MIRT1995632	hsa-miR-3156-3p	CLIP-seq
MIRT1995633	hsa-miR-3692	CLIP-seq
MIRT1995634	hsa-miR-4301	CLIP-seq
MIRT1995635	hsa-miR-4330	CLIP-seq
MIRT997003	hsa-miR-4450	CLIP-seq
MIRT1995636	hsa-miR-4525	CLIP-seq
MIRT1995637	hsa-miR-4728-5p	CLIP-seq
MIRT1995638	hsa-miR-4733-3p	CLIP-seq
MIRT1995639	hsa-miR-513a-5p	CLIP-seq
MIRT1995640	hsa-miR-532-3p	CLIP-seq
MIRT1995641	hsa-miR-542-5p	CLIP-seq
MIRT2229629	hsa-miR-1258	CLIP-seq
MIRT2229630	hsa-miR-1266	CLIP-seq
MIRT996963	hsa-miR-1273f	CLIP-seq
MIRT996969	hsa-miR-185	CLIP-seq
MIRT2229631	hsa-miR-24	CLIP-seq
MIRT2229632	hsa-miR-3155	CLIP-seq
MIRT2229633	hsa-miR-3155b	CLIP-seq
MIRT2229634	hsa-miR-3649	CLIP-seq
MIRT2229635	hsa-miR-3664-3p	CLIP-seq
MIRT2229636	hsa-miR-3675-5p	CLIP-seq
MIRT996996	hsa-miR-4270	CLIP-seq
MIRT996998	hsa-miR-4306	CLIP-seq
MIRT2229637	hsa-miR-4433	CLIP-seq
MIRT997001	hsa-miR-4441	CLIP-seq
MIRT2229638	hsa-miR-4459	CLIP-seq
MIRT2229639	hsa-miR-4518	CLIP-seq
MIRT997009	hsa-miR-4534	CLIP-seq
MIRT997012	hsa-miR-4644	CLIP-seq
MIRT2229640	hsa-miR-4685-5p	CLIP-seq
MIRT997026	hsa-miR-4756-3p	CLIP-seq
MIRT997027	hsa-miR-4761-5p	CLIP-seq
MIRT2229641	hsa-miR-4768-3p	CLIP-seq
MIRT2229642	hsa-miR-760	CLIP-seq
MIRT996963	hsa-miR-1273f	CLIP-seq
MIRT996969	hsa-miR-185	CLIP-seq
MIRT996998	hsa-miR-4306	CLIP-seq
MIRT997009	hsa-miR-4534	CLIP-seq
MIRT997012	hsa-miR-4644	CLIP-seq
MIRT997026	hsa-miR-4756-3p	CLIP-seq

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence
GO:0000785	Component	Chromatin	IEA
GO:0000785	Component	Chromatin	ISS
GO:0003713	Function	Transcription coactivator activity	ISS
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0008270	Function	Zinc ion binding	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	IEA
GO:0030971	Function	Receptor tyrosine kinase binding	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0061629	Function	RNA polymerase II-specific DNA-binding transcription factor binding	ISS

MIM	HGNC	e!Ensembl
609133	25917	ENSG00000179943

Q96SL8

Protein name

Flt3-interacting zinc finger protein 1 (Zinc finger protein 798)

Protein function

May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	23 → 45	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	51 → 73	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	228 → 250	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	470 → 492	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:12566383}.

Sequence

MDDVPAPTPAPAPPAAAAPRVPFHCSECGKSFRYRSDLRRHFARHTALKPHACPRCGKGF
KHSFNLANHLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSRS
SLGRHLKRQHRGVLPSPLQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAG
LGSWGLAEAAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAP
ALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPAGG
GVPKLGGLLPEGGGEAPAPAAAAEPSEDTLYQCDCGTFFASAAALASHLEAHSGPATYGC
GHCGALYAALAALEEHRRVSHGEGGGEEAATAAREREPASGEPPSGSGRGKKIFGCSECE
KLFRSPRDLERHVLVHTGEKPFPCLECGKFFRHECYLKRHRLLHGTERPFPCHICGKGFI
TLSNLSRHLKLHRGMD

Sequence length

496

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
PERIODONTITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

FIZ1 (FLT3 interacting zinc finger 1)