Gene Gene information from NCBI Gene database.
Entrez ID 84747
Gene name Unc-119 lipid binding chaperone B
Gene symbol UNC119B
Synonyms (NCBI Gene)
POC7B
Chromosome 12
Chromosome location 12q24.31
miRNA miRNA information provided by mirtarbase database.
671
miRTarBase ID miRNA Experiments Reference
MIRT024043 hsa-miR-1-3p Microarray 18668037
MIRT651870 hsa-miR-216b-5p HITS-CLIP 23824327
MIRT651869 hsa-miR-4762-5p HITS-CLIP 23824327
MIRT651868 hsa-miR-3919 HITS-CLIP 23824327
MIRT651867 hsa-miR-2467-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 22085962, 22960633, 33961781
GO:0005829 Component Cytosol TAS
GO:0005929 Component Cilium IBA
GO:0005929 Component Cilium IEA
GO:0005929 Component Cilium TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620513 16488 ENSG00000175970
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A6NIH7
Protein name Protein unc-119 homolog B
Protein function Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localiza
PDB 7OK6 , 7OK7
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05351 GMP_PDE_delta 88 247 GMP-PDE, delta subunit Family
Sequence
Sequence length 251
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Trafficking of myristoylated proteins to the cilium
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
TYPE 2 DIABETES MELLITUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 37903971 Associate
★☆☆☆☆
Found in Text Mining only