Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84689
Gene name	Membrane spanning 4-domains A14
Gene symbol	MS4A14
Synonyms (NCBI Gene)	MS4A16NYD-SP21
Chromosome	11
Chromosome location	11q12.2

Show/Hide all (16)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018213	hsa-miR-335-5p	Microarray	18185580
MIRT1160941	hsa-miR-140-3p	CLIP-seq
MIRT1160942	hsa-miR-146a	CLIP-seq
MIRT1160943	hsa-miR-146b-5p	CLIP-seq
MIRT1160944	hsa-miR-3688-5p	CLIP-seq
MIRT1160945	hsa-miR-580	CLIP-seq
MIRT1160946	hsa-miR-589	CLIP-seq
MIRT1551392	hsa-miR-1202	CLIP-seq
MIRT1551393	hsa-miR-1825	CLIP-seq
MIRT1551394	hsa-miR-3671	CLIP-seq
MIRT1551395	hsa-miR-3972	CLIP-seq
MIRT1551396	hsa-miR-3977	CLIP-seq
MIRT1551397	hsa-miR-4776-3p	CLIP-seq
MIRT1551398	hsa-miR-520f	CLIP-seq
MIRT1551399	hsa-miR-579	CLIP-seq
MIRT1551400	hsa-miR-607	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005886	Component	Plasma membrane	IBA
GO:0007166	Process	Cell surface receptor signaling pathway	IBA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q96JA4

Protein name

Membrane-spanning 4-domains subfamily A member 14 (Testis development protein NYD-SP21)

Protein function

May be involved in signal transduction as a component of a multimeric receptor complex.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04103	CD20	44 → 202	CD20-like family	Family

Sequence

MESTSQDRRATHVITIKPNETVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFG
TIFALNYIGFSQRLPLVVLTGYPFWGALIFILTGYLTVTDKKSKLLGQGVTGMNVISSLV
AITGITFTILSYRHQDKYCQMPSFEEICVFSRTLFIVLFFLPSDVTQNSEQPAPEENDQL
QFVLQEEFSSDDSTTNAQSVIFGGYAFFKLTLSRSPLVSQPGNKGREFVPDEQKQSILPS
PKFSEEEIEPLPPTLEKKPSENMSIQLDSTFKQMKDEDLQSAIVQPSQMQTKLLQDQAAS
LQVFPSHSALKLEDISPEDLPSQALPVEGLSEQTMPSKSTSSHVKQSSNLTANDLPPQGI
LSQDTSSQDMLFHDMTSQDMQSLDMLSQDTPSHAMPPQDIPSQDMLSQALSAHAILPEAS
TSHIVQFPEIQHLLQQPPDLQPENTEPQNQQILQMSYQDIRSEVMEETKEWKSEEELHRR
KSSRRHSLNQQTKALQYLRRHSLDVQAKGQKSSKRHSLDQQSKGWQSPKQKSLDQQIKDW
LSPKRHSVDKQAQLNQTKEQLPDQQAEDQQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQ
TQDQQTEDQPAQEKKSPKGQFQNVQAEGQQAQVEKVPKLLCQDSESQIQQYQFWQFHKGN
LQAGQPRTVNLLAKNPLTG

Sequence length

679

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Essential tremor	Uncertain significance	ClinVar Disgenet	★★★★★ ★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Behcet Syndrome	Behcet disease	Pubtator	36226612	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★★★★★ ★☆☆☆☆ Found in Text Mining only

MS4A14 (membrane spanning 4-domains A14)