ACCS (1-aminocyclopropane-1-carboxylate synthase homolog (inactive))

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 84680
Gene name 1-aminocyclopropane-1-carboxylate synthase homolog (inactive)
Gene symbol ACCS
Synonyms (NCBI Gene)
ACSPHACS
Chromosome 11
Chromosome location 11p11.2
miRNA miRNA information provided by mirtarbase database.
15
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (15)
miRTarBase ID miRNA Experiments Reference
MIRT762436 hsa-miR-1260 CLIP-seq
MIRT762437 hsa-miR-1260b CLIP-seq
MIRT762438 hsa-miR-140-3p CLIP-seq
MIRT762439 hsa-miR-188-3p CLIP-seq
MIRT762440 hsa-miR-3156-3p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 35156780
GO:0006520 Process Amino acid metabolic process IBA
GO:0008483 Function Transaminase activity IBA
GO:0016847 Function 1-aminocyclopropane-1-carboxylate synthase activity IDA 11470512
GO:0030170 Function Pyridoxal phosphate binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
608405 23989 ENSG00000110455
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96QU6
Protein name 1-aminocyclopropane-1-carboxylate synthase-like protein 1 (ACC synthase-like protein 1)
Protein function Does not catalyze the synthesis of 1-aminocyclopropane-1-carboxylate but is capable of catalyzing the deamination of L-vinylglycine.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00155 Aminotran_1_2 96 → 468 Aminotransferase class I and II Domain
Sequence
Sequence length 501
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (1)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
IGA GLOMERULONEPHRITIS — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (101)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Acute Coronary Syndrome Coronary Syndrome BEFREE 17706812, 22575314, 23136988, 28089149, 28233628, 28267469, 28511772, 28545849, 28838475, 28855078, 28947562, 28982673, 29437596, 29499359, 29601956
View all (24 more)
★★★★★
★☆☆☆☆
Found in Text Mining only
Acute lymphocytic leukemia Lymphocytic Leukemia BEFREE 30023654
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenocarcinoma of pancreas Pancreatic adenocarcinoma BEFREE 28747265
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenoid Cystic Carcinoma Adenocarcinoma BEFREE 15521066, 21258767, 22931165
★★★★★
★☆☆☆☆
Found in Text Mining only
Adult Acute Lymphocytic Leukemia Lymphocytic Leukemia BEFREE 30023654
★★★★★
★☆☆☆☆
Found in Text Mining only
Aortic Aneurysm, Abdominal Aortic Aneurysm BEFREE 28483623, 31226476
★★★★★
★☆☆☆☆
Found in Text Mining only
Aortic Valve Insufficiency Aortic Valve Insufficiency BEFREE 29288564
★★★★★
★☆☆☆☆
Found in Text Mining only
Appendicitis Appendicitis BEFREE 28654543, 28693849, 30635205, 31388806
★★★★★
★☆☆☆☆
Found in Text Mining only
Arteriosclerosis Arteriosclerosis BEFREE 27796172, 31504738
★★★★★
★☆☆☆☆
Found in Text Mining only
Atherosclerosis Atherosclerosis BEFREE 27796172, 31504738
★★★★★
★☆☆☆☆
Found in Text Mining only