Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84460
Gene name	Zinc finger matrin-type 1
Gene symbol	ZMAT1
Synonyms (NCBI Gene)	-
Chromosome	X
Chromosome location	Xq22.1
Summary	This gene encodes a protein containing Cys2-His2 (C2H2)-type zinc fingers, which are similar to those found in the nuclear matrix protein matrin 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Show/Hide all (54)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018428	hsa-miR-335-5p	Microarray	18185580
MIRT709972	hsa-miR-548n	HITS-CLIP	19536157
MIRT709971	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT709970	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT709969	hsa-miR-6507-5p	HITS-CLIP	19536157
MIRT640813	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT640812	hsa-miR-1248	HITS-CLIP	23824327
MIRT640811	hsa-miR-3119	HITS-CLIP	23824327
MIRT640810	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT640809	hsa-miR-6740-5p	HITS-CLIP	23824327
MIRT640808	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT640807	hsa-miR-4674	HITS-CLIP	23824327
MIRT640806	hsa-miR-1587	HITS-CLIP	23824327
MIRT640805	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT709972	hsa-miR-548n	HITS-CLIP	19536157
MIRT709971	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT709970	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT709969	hsa-miR-6507-5p	HITS-CLIP	19536157
MIRT640813	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT640812	hsa-miR-1248	HITS-CLIP	23824327
MIRT640811	hsa-miR-3119	HITS-CLIP	23824327
MIRT640810	hsa-miR-27a-5p	HITS-CLIP	23824327
MIRT640809	hsa-miR-6740-5p	HITS-CLIP	23824327
MIRT640808	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT640807	hsa-miR-4674	HITS-CLIP	23824327
MIRT640806	hsa-miR-1587	HITS-CLIP	23824327
MIRT640805	hsa-miR-3620-5p	HITS-CLIP	23824327
MIRT1514077	hsa-miR-151-3p	CLIP-seq
MIRT1514078	hsa-miR-4275	CLIP-seq
MIRT1514079	hsa-miR-4463	CLIP-seq
MIRT1514080	hsa-miR-4499	CLIP-seq
MIRT1514081	hsa-miR-452	CLIP-seq
MIRT1514082	hsa-miR-4659a-3p	CLIP-seq
MIRT1514083	hsa-miR-4659b-3p	CLIP-seq
MIRT1514084	hsa-miR-4676-3p	CLIP-seq
MIRT1514085	hsa-miR-4778-3p	CLIP-seq
MIRT1514086	hsa-miR-4795-3p	CLIP-seq
MIRT1514087	hsa-miR-513a-3p	CLIP-seq
MIRT1514088	hsa-miR-579	CLIP-seq
MIRT2155060	hsa-miR-3692	CLIP-seq
MIRT2155061	hsa-miR-578	CLIP-seq
MIRT1514088	hsa-miR-579	CLIP-seq
MIRT2374990	hsa-miR-2116	CLIP-seq
MIRT2374991	hsa-miR-320a	CLIP-seq
MIRT2374992	hsa-miR-320b	CLIP-seq
MIRT2374993	hsa-miR-320c	CLIP-seq
MIRT2374994	hsa-miR-320d	CLIP-seq
MIRT2374995	hsa-miR-4257	CLIP-seq
MIRT2374996	hsa-miR-4329	CLIP-seq
MIRT2374997	hsa-miR-4330	CLIP-seq
MIRT2374998	hsa-miR-4429	CLIP-seq
MIRT2374999	hsa-miR-4677-5p	CLIP-seq
MIRT2375000	hsa-miR-4789-3p	CLIP-seq
MIRT2375001	hsa-miR-642b	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
301007	29377	ENSG00000166432

Q5H9K5

Protein name

Zinc finger matrin-type protein 1

Family and domains

Pfam

Accession	ID	Position in sequence	Type
PF12874	zf-met	56 → 80	Domain
PF12874	zf-met	121 → 145	Domain
PF12874	zf-met	175 → 199	Domain

Sequence

MESCSVTRLECSGAISAHCSLHLPGSSDSPASASQIAGTTDAIWNEQEKAELFTDKFCQV
CGVMLQFESQRISHYEGEKHAQNVSFYFQMHGEQNEVPGKKMKMHVENFQVHRYEGVDKN
KFCDLCNMMFSSPLIAQSHYVGKVHAKKLKQLMEEHDQASPSGFQPEMAFSMRTYVCHIC
SIAFTSLDMFRSHMQGSEHQIKESIVINLVKNSRKTQDSYQNECADYINVQKARGLEAKT
CFRKMEESSLETRRYREVVDSRPRHRMFEQRLPFETFRTYAAPYNISQAMEKQLPHSKKT
YDSFQDELEDYIKVQKARGLDPKTCFRKMRENSVDTHGYREMVDSGPRSRMCEQRFSHEA
SQTYQRPYHISPVESQLPQWLPTHSKRTYDSFQDELEDYIKVQKARGLEPKTCFRKIGDS
SVETHRNREMVDVRPRHRMLEQKLPCETFQTYSGPYSISQVVENQLPHCLPAHDSKQRLD
SISYCQLTRDCFPEKPVPLSLNQQENNSGSYSVESEVYKHLSSENNTADHQAGHKQKHQK
RKRHLEEGKERPEKEQSKHKRKKSYEDTDLDKDKSIRQRKREEDRVKVSSGKLKHRKKKK
SHDVPSEKEERKHRKEKKKSVEERTEEEMLWDESILGF

Sequence length

638

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Abnormality of neuronal migration	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma Pancreatic Ductal	Pancreatic ductal carcinoma	Pubtator	35392973	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	32751923	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	26191264	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	26191264		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	26191264		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	35392973	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	26191264		★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	26191264	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZMAT1 (zinc finger matrin-type 1)