DYDC2 (DPY30 domain containing 2)

Gene

• Entrez ID: 84332
• Gene name: DPY30 domain containing 2
• Gene symbol: DYDC2
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10q23.1
• Summary: This gene encodes a member of a family of proteins that contains a DPY30 domain. This gene locus overlaps with a closely related gene on the opposite strand. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT948784	hsa-miR-1304	CLIP-seq
MIRT948785	hsa-miR-1827	CLIP-seq
MIRT948786	hsa-miR-224	CLIP-seq
MIRT948787	hsa-miR-3125	CLIP-seq
MIRT948788	hsa-miR-3147	CLIP-seq
MIRT948789	hsa-miR-3148	CLIP-seq
MIRT948790	hsa-miR-3161	CLIP-seq
MIRT948791	hsa-miR-3591-5p	CLIP-seq
MIRT948792	hsa-miR-3689a-3p	CLIP-seq
MIRT948793	hsa-miR-3689c	CLIP-seq
MIRT948794	hsa-miR-3916	CLIP-seq
MIRT948795	hsa-miR-4255	CLIP-seq
MIRT948796	hsa-miR-4328	CLIP-seq
MIRT948797	hsa-miR-4425	CLIP-seq
MIRT948798	hsa-miR-450b-5p	CLIP-seq
MIRT948799	hsa-miR-4696	CLIP-seq
MIRT948800	hsa-miR-4732-5p	CLIP-seq
MIRT948801	hsa-miR-507	CLIP-seq
MIRT948802	hsa-miR-557	CLIP-seq
MIRT1548086	hsa-miR-185	CLIP-seq
MIRT1548087	hsa-miR-3150a-3p	CLIP-seq
MIRT1548088	hsa-miR-3175	CLIP-seq
MIRT1548089	hsa-miR-4306	CLIP-seq
MIRT948796	hsa-miR-4328	CLIP-seq
MIRT1548090	hsa-miR-4492	CLIP-seq
MIRT1548091	hsa-miR-4498	CLIP-seq
MIRT1548092	hsa-miR-4505	CLIP-seq
MIRT948798	hsa-miR-450b-5p	CLIP-seq
MIRT1548093	hsa-miR-4644	CLIP-seq
MIRT1548094	hsa-miR-4667-5p	CLIP-seq
MIRT948799	hsa-miR-4696	CLIP-seq
MIRT1548095	hsa-miR-4700-5p	CLIP-seq
MIRT1548096	hsa-miR-4731-5p	CLIP-seq
MIRT948800	hsa-miR-4732-5p	CLIP-seq
MIRT948801	hsa-miR-507	CLIP-seq
MIRT1548097	hsa-miR-539	CLIP-seq
MIRT948802	hsa-miR-557	CLIP-seq
MIRT1548098	hsa-miR-762	CLIP-seq
MIRT1548099	hsa-miR-939	CLIP-seq
MIRT948796	hsa-miR-4328	CLIP-seq
MIRT948798	hsa-miR-450b-5p	CLIP-seq
MIRT948799	hsa-miR-4696	CLIP-seq
MIRT948800	hsa-miR-4732-5p	CLIP-seq
MIRT948801	hsa-miR-507	CLIP-seq
MIRT948802	hsa-miR-557	CLIP-seq
MIRT948788	hsa-miR-3147	CLIP-seq
MIRT948792	hsa-miR-3689a-3p	CLIP-seq
MIRT948793	hsa-miR-3689c	CLIP-seq
MIRT948796	hsa-miR-4328	CLIP-seq
MIRT948797	hsa-miR-4425	CLIP-seq
MIRT948798	hsa-miR-450b-5p	CLIP-seq
MIRT948799	hsa-miR-4696	CLIP-seq
MIRT948800	hsa-miR-4732-5p	CLIP-seq
MIRT2216236	hsa-miR-4753-3p	CLIP-seq
MIRT2216237	hsa-miR-4768-5p	CLIP-seq
MIRT948801	hsa-miR-507	CLIP-seq
MIRT2216238	hsa-miR-548c-3p	CLIP-seq
MIRT948802	hsa-miR-557	CLIP-seq
MIRT948796	hsa-miR-4328	CLIP-seq
MIRT948798	hsa-miR-450b-5p	CLIP-seq
MIRT948799	hsa-miR-4696	CLIP-seq
MIRT948800	hsa-miR-4732-5p	CLIP-seq
MIRT948801	hsa-miR-507	CLIP-seq
MIRT948802	hsa-miR-557	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 19447967, 31515488, 32296183, 33961781
GO:0048188	Component	Set1C/COMPASS complex	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96IM9
• Protein name: DPY30 domain-containing protein 2
• PDB: 8J07
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05186	Dpy-30	1 → 42	Dpy-30 motif	Motif

• Sequence:

  METNYLKRCFGNCLAQALAEVAKVRPSDPIEYLAHWLYHYRKTAKAKEENREKKIHLQEE
  YDSSLKEMEMTEMLKQEEYQIQQNCEKCHKELTSETVSTKKTIFMQEDTNPLEKEALKQE
  FLPGTSSLIPGMPQQVPPSESAGQIDQNFKMPQEINYKEAFQHEVAHEMPPGSKSPF

• Sequence length: 177

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
GOUT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SARCOIDOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations