Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84287
Gene name	ZDHHC palmitoyltransferase 16
Gene symbol	ZDHHC16
Synonyms (NCBI Gene)	APH2DHHC-16
Chromosome	10
Chromosome location	10q24.1

113

Show/Hide all (113)

miRTarBase ID	miRNA	Experiments	Reference
MIRT057733	hsa-miR-34a-5p	PAR-CLIP	21572407
MIRT057736	hsa-miR-34c-5p	PAR-CLIP	21572407
MIRT057738	hsa-miR-449a	PAR-CLIP	21572407
MIRT057740	hsa-miR-449b-5p	PAR-CLIP	21572407
MIRT057729	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT057734	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT057730	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT057735	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT057737	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT057739	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT057752	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT057744	hsa-miR-3607-5p	PAR-CLIP	21572407
MIRT057743	hsa-miR-4287	PAR-CLIP	21572407
MIRT057747	hsa-miR-4685-3p	PAR-CLIP	21572407
MIRT057748	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT057742	hsa-miR-1253	PAR-CLIP	21572407
MIRT057750	hsa-miR-6770-5p	PAR-CLIP	21572407
MIRT057731	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT057732	hsa-miR-107	PAR-CLIP	21572407
MIRT057753	hsa-miR-7106-3p	PAR-CLIP	21572407
MIRT545914	hsa-miR-548au-3p	PAR-CLIP	21572407
MIRT057751	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT057746	hsa-miR-4503	PAR-CLIP	21572407
MIRT057733	hsa-miR-34a-5p	PAR-CLIP	21572407
MIRT057736	hsa-miR-34c-5p	PAR-CLIP	21572407
MIRT057738	hsa-miR-449a	PAR-CLIP	21572407
MIRT057740	hsa-miR-449b-5p	PAR-CLIP	21572407
MIRT057729	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT057734	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT057730	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT057735	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT057737	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT057739	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT057752	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT057744	hsa-miR-3607-5p	PAR-CLIP	21572407
MIRT057743	hsa-miR-4287	PAR-CLIP	21572407
MIRT057747	hsa-miR-4685-3p	PAR-CLIP	21572407
MIRT057748	hsa-miR-4795-5p	PAR-CLIP	21572407
MIRT057742	hsa-miR-1253	PAR-CLIP	21572407
MIRT057750	hsa-miR-6770-5p	PAR-CLIP	21572407
MIRT057731	hsa-miR-103a-3p	PAR-CLIP	21572407
MIRT057732	hsa-miR-107	PAR-CLIP	21572407
MIRT057753	hsa-miR-7106-3p	PAR-CLIP	21572407
MIRT545914	hsa-miR-548au-3p	PAR-CLIP	21572407
MIRT057751	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT057746	hsa-miR-4503	PAR-CLIP	21572407
MIRT1507839	hsa-miR-103a	CLIP-seq
MIRT1507840	hsa-miR-15a	CLIP-seq
MIRT1507841	hsa-miR-15b	CLIP-seq
MIRT1507842	hsa-miR-16	CLIP-seq
MIRT1507843	hsa-miR-1910	CLIP-seq
MIRT1507844	hsa-miR-195	CLIP-seq
MIRT1507845	hsa-miR-223	CLIP-seq
MIRT1507846	hsa-miR-3152-5p	CLIP-seq
MIRT1507847	hsa-miR-3170	CLIP-seq
MIRT1507848	hsa-miR-3182	CLIP-seq
MIRT1507849	hsa-miR-34a	CLIP-seq
MIRT1507850	hsa-miR-424	CLIP-seq
MIRT1507851	hsa-miR-449b	CLIP-seq
MIRT1507852	hsa-miR-455-3p	CLIP-seq
MIRT1507853	hsa-miR-4652-3p	CLIP-seq
MIRT1507854	hsa-miR-4667-5p	CLIP-seq
MIRT1507855	hsa-miR-4697-3p	CLIP-seq
MIRT1507856	hsa-miR-4700-5p	CLIP-seq
MIRT1507857	hsa-miR-4774-3p	CLIP-seq
MIRT1507858	hsa-miR-497	CLIP-seq
MIRT1507859	hsa-miR-637	CLIP-seq
MIRT1507848	hsa-miR-3182	CLIP-seq
MIRT2373258	hsa-miR-1184	CLIP-seq
MIRT2373259	hsa-miR-1205	CLIP-seq
MIRT2373260	hsa-miR-3158-5p	CLIP-seq
MIRT1507848	hsa-miR-3182	CLIP-seq
MIRT1507849	hsa-miR-34a	CLIP-seq
MIRT2373261	hsa-miR-4289	CLIP-seq
MIRT1507851	hsa-miR-449b	CLIP-seq
MIRT2373262	hsa-miR-4659a-3p	CLIP-seq
MIRT2373263	hsa-miR-4659b-3p	CLIP-seq
MIRT2373264	hsa-miR-4711-3p	CLIP-seq
MIRT2373265	hsa-miR-511	CLIP-seq
MIRT2373266	hsa-miR-544	CLIP-seq
MIRT2373267	hsa-miR-592	CLIP-seq
MIRT2373268	hsa-miR-599	CLIP-seq
MIRT1507843	hsa-miR-1910	CLIP-seq
MIRT1507845	hsa-miR-223	CLIP-seq
MIRT1507846	hsa-miR-3152-5p	CLIP-seq
MIRT1507847	hsa-miR-3170	CLIP-seq
MIRT1507848	hsa-miR-3182	CLIP-seq
MIRT2373261	hsa-miR-4289	CLIP-seq
MIRT1507852	hsa-miR-455-3p	CLIP-seq
MIRT1507853	hsa-miR-4652-3p	CLIP-seq
MIRT1507854	hsa-miR-4667-5p	CLIP-seq
MIRT1507855	hsa-miR-4697-3p	CLIP-seq
MIRT1507856	hsa-miR-4700-5p	CLIP-seq
MIRT2373264	hsa-miR-4711-3p	CLIP-seq
MIRT1507857	hsa-miR-4774-3p	CLIP-seq
MIRT2373265	hsa-miR-511	CLIP-seq
MIRT2666095	hsa-miR-515-5p	CLIP-seq
MIRT2373267	hsa-miR-592	CLIP-seq
MIRT2373268	hsa-miR-599	CLIP-seq
MIRT1507859	hsa-miR-637	CLIP-seq
MIRT1507843	hsa-miR-1910	CLIP-seq
MIRT1507845	hsa-miR-223	CLIP-seq
MIRT1507846	hsa-miR-3152-5p	CLIP-seq
MIRT1507847	hsa-miR-3170	CLIP-seq
MIRT1507848	hsa-miR-3182	CLIP-seq
MIRT1507852	hsa-miR-455-3p	CLIP-seq
MIRT1507853	hsa-miR-4652-3p	CLIP-seq
MIRT1507854	hsa-miR-4667-5p	CLIP-seq
MIRT1507855	hsa-miR-4697-3p	CLIP-seq
MIRT1507856	hsa-miR-4700-5p	CLIP-seq
MIRT1507857	hsa-miR-4774-3p	CLIP-seq
MIRT2666095	hsa-miR-515-5p	CLIP-seq
MIRT1507859	hsa-miR-637	CLIP-seq

Show/Hide all (23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001654	Process	Eye development	IEA
GO:0001654	Process	Eye development	ISS
GO:0005515	Function	Protein binding	IPI	28826475, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0006915	Process	Apoptotic process	IEA
GO:0006974	Process	DNA damage response	IBA
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	ISS
GO:0007507	Process	Heart development	IBA
GO:0007507	Process	Heart development	IEA
GO:0007507	Process	Heart development	ISS
GO:0016020	Component	Membrane	IEA
GO:0016409	Function	Palmitoyltransferase activity	IBA
GO:0016409	Function	Palmitoyltransferase activity	IDA	23034182
GO:0016409	Function	Palmitoyltransferase activity	IEA
GO:0016409	Function	Palmitoyltransferase activity	IMP	28826475
GO:0016740	Function	Transferase activity	IEA
GO:0016746	Function	Acyltransferase activity	IEA
GO:0019706	Function	Protein-cysteine S-palmitoyltransferase activity	IEA
GO:0021537	Process	Telencephalon development	ISS
GO:0021899	Process	Fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment	IBA

MIM	HGNC	e!Ensembl
616750	20714	ENSG00000171307

Q969W1

Protein name

Palmitoyltransferase ZDHHC16 (EC 2.3.1.225) (Abl-philin 2) (Zinc finger DHHC domain-containing protein 16) (DHHC-16)

Protein function

Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (PubMed:28826475). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN pho

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01529	DHHC	151 → 305	DHHC palmitoyltransferase	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:17123647}.

Sequence

MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTA
VDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFF
YSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLK
MDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKL
QAVANQTYHQTPPPTFSFRERMTHKSLVYLWFLCSSVALALGALTVWHAVLISRGETSIE
RHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMS
WEPPPWVTAHSASVMAV

Sequence length

377

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
INTELLECTUAL DISABILITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adult T-Cell Lymphoma/Leukemia	T-Cell Lymphoma/Leukemia	BEFREE	31597781	★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	27110706	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZDHHC16 (zDHHC palmitoyltransferase 16)