Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	84269
Gene name	Coiled-coil-helix-coiled-coil-helix domain containing 5
Gene symbol	CHCHD5
Synonyms (NCBI Gene)	C2orf9CHTM1MIC14MIX14
Chromosome	2
Chromosome location	2q14.1

250

Show/Hide all (250)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049489	hsa-miR-92a-3p	CLASH	23622248
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT670107	hsa-miR-764	HITS-CLIP	23824327
MIRT670106	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT670105	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT670104	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT670103	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT670102	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT670101	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT670100	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679046	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT670099	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT670098	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679045	hsa-miR-6131	HITS-CLIP	23824327
MIRT670097	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT679044	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679043	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT670107	hsa-miR-764	HITS-CLIP	23824327
MIRT670106	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT670105	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT670104	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT670103	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT670102	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT670101	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT670100	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT670099	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT670098	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT659538	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT670097	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT659556	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT659555	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT659554	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT659553	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT659552	hsa-miR-302e	HITS-CLIP	23824327
MIRT659551	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT659550	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT659549	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT659548	hsa-miR-520b	HITS-CLIP	23824327
MIRT659547	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT659546	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT659545	hsa-miR-520e	HITS-CLIP	23824327
MIRT659544	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659541	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT659538	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT659537	hsa-miR-4731-5p	HITS-CLIP	23824327
MIRT659536	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT618162	hsa-miR-576-3p	HITS-CLIP	23824327
MIRT618161	hsa-miR-6888-5p	HITS-CLIP	23824327
MIRT618160	hsa-miR-4501	HITS-CLIP	23824327
MIRT618159	hsa-miR-3938	HITS-CLIP	23824327
MIRT618158	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT618157	hsa-miR-3150b-3p	HITS-CLIP	23824327
MIRT618156	hsa-miR-4784	HITS-CLIP	23824327
MIRT618155	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT618154	hsa-miR-6077	HITS-CLIP	23824327
MIRT618153	hsa-miR-7973	HITS-CLIP	23824327
MIRT618152	hsa-miR-623	HITS-CLIP	23824327
MIRT618151	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT618150	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT618149	hsa-miR-192-5p	HITS-CLIP	23824327
MIRT618148	hsa-miR-215-5p	HITS-CLIP	23824327
MIRT618147	hsa-miR-4689	HITS-CLIP	23824327
MIRT618146	hsa-miR-6858-5p	HITS-CLIP	23824327
MIRT618145	hsa-miR-6079	HITS-CLIP	23824327
MIRT618144	hsa-miR-6808-3p	HITS-CLIP	23824327
MIRT618143	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT618142	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT618141	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT618140	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT670107	hsa-miR-764	HITS-CLIP	23824327
MIRT670106	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT670105	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT670104	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT670103	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT670102	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT670101	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT670100	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679046	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT670099	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT670098	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679045	hsa-miR-6131	HITS-CLIP	23824327
MIRT670097	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT679044	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT679043	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT670107	hsa-miR-764	HITS-CLIP	23824327
MIRT670106	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT670105	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT670104	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT670103	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT670102	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT670101	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT670100	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT670099	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT670098	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT659538	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT670097	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT659556	hsa-miR-302a-3p	HITS-CLIP	23824327
MIRT659555	hsa-miR-302b-3p	HITS-CLIP	23824327
MIRT659554	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT659553	hsa-miR-302d-3p	HITS-CLIP	23824327
MIRT659552	hsa-miR-302e	HITS-CLIP	23824327
MIRT659551	hsa-miR-372-3p	HITS-CLIP	23824327
MIRT659550	hsa-miR-373-3p	HITS-CLIP	23824327
MIRT659549	hsa-miR-520a-3p	HITS-CLIP	23824327
MIRT659548	hsa-miR-520b	HITS-CLIP	23824327
MIRT659547	hsa-miR-520c-3p	HITS-CLIP	23824327
MIRT659546	hsa-miR-520d-3p	HITS-CLIP	23824327
MIRT659545	hsa-miR-520e	HITS-CLIP	23824327
MIRT659544	hsa-miR-512-3p	HITS-CLIP	23824327
MIRT659543	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT659542	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT659541	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT659540	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT659539	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT659538	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT659537	hsa-miR-4731-5p	HITS-CLIP	23824327
MIRT659536	hsa-miR-5589-5p	HITS-CLIP	23824327
MIRT659535	hsa-miR-640	HITS-CLIP	23824327
MIRT618162	hsa-miR-576-3p	HITS-CLIP	23824327
MIRT618161	hsa-miR-6888-5p	HITS-CLIP	23824327
MIRT618160	hsa-miR-4501	HITS-CLIP	23824327
MIRT618159	hsa-miR-3938	HITS-CLIP	23824327
MIRT618158	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT618157	hsa-miR-3150b-3p	HITS-CLIP	23824327
MIRT618156	hsa-miR-4784	HITS-CLIP	23824327
MIRT618155	hsa-miR-7-5p	HITS-CLIP	23824327
MIRT618154	hsa-miR-6077	HITS-CLIP	23824327
MIRT618153	hsa-miR-7973	HITS-CLIP	23824327
MIRT618152	hsa-miR-623	HITS-CLIP	23824327
MIRT618151	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT618150	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT618149	hsa-miR-192-5p	HITS-CLIP	23824327
MIRT618148	hsa-miR-215-5p	HITS-CLIP	23824327
MIRT618147	hsa-miR-4689	HITS-CLIP	23824327
MIRT618146	hsa-miR-6858-5p	HITS-CLIP	23824327
MIRT618145	hsa-miR-6079	HITS-CLIP	23824327
MIRT618144	hsa-miR-6808-3p	HITS-CLIP	23824327
MIRT618143	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT618142	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT618141	hsa-miR-7850-5p	HITS-CLIP	23824327
MIRT618140	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT888697	hsa-miR-1184	CLIP-seq
MIRT888698	hsa-miR-1205	CLIP-seq
MIRT888699	hsa-miR-1268	CLIP-seq
MIRT888700	hsa-miR-1268b	CLIP-seq
MIRT888701	hsa-miR-1909	CLIP-seq
MIRT888702	hsa-miR-198	CLIP-seq
MIRT888703	hsa-miR-24	CLIP-seq
MIRT888704	hsa-miR-3126-3p	CLIP-seq
MIRT888705	hsa-miR-3158-5p	CLIP-seq
MIRT888706	hsa-miR-3176	CLIP-seq
MIRT888707	hsa-miR-3184	CLIP-seq
MIRT888708	hsa-miR-3664-3p	CLIP-seq
MIRT888709	hsa-miR-3922-3p	CLIP-seq
MIRT888710	hsa-miR-423-5p	CLIP-seq
MIRT888711	hsa-miR-4436a	CLIP-seq
MIRT888712	hsa-miR-4437	CLIP-seq
MIRT888713	hsa-miR-4447	CLIP-seq
MIRT888714	hsa-miR-4472	CLIP-seq
MIRT888715	hsa-miR-4488	CLIP-seq
MIRT888716	hsa-miR-4641	CLIP-seq
MIRT888717	hsa-miR-4685-5p	CLIP-seq
MIRT888718	hsa-miR-4697-5p	CLIP-seq
MIRT888719	hsa-miR-4701-5p	CLIP-seq
MIRT888720	hsa-miR-4728-5p	CLIP-seq
MIRT888721	hsa-miR-4797-5p	CLIP-seq
MIRT888722	hsa-miR-486-3p	CLIP-seq
MIRT888723	hsa-miR-588	CLIP-seq
MIRT888724	hsa-miR-665	CLIP-seq
MIRT888725	hsa-miR-924	CLIP-seq
MIRT888703	hsa-miR-24	CLIP-seq
MIRT888704	hsa-miR-3126-3p	CLIP-seq
MIRT888706	hsa-miR-3176	CLIP-seq
MIRT888708	hsa-miR-3664-3p	CLIP-seq
MIRT888709	hsa-miR-3922-3p	CLIP-seq
MIRT888711	hsa-miR-4436a	CLIP-seq
MIRT888712	hsa-miR-4437	CLIP-seq
MIRT888717	hsa-miR-4685-5p	CLIP-seq
MIRT888719	hsa-miR-4701-5p	CLIP-seq
MIRT888723	hsa-miR-588	CLIP-seq
MIRT888697	hsa-miR-1184	CLIP-seq
MIRT888698	hsa-miR-1205	CLIP-seq
MIRT888699	hsa-miR-1268	CLIP-seq
MIRT888700	hsa-miR-1268b	CLIP-seq
MIRT888701	hsa-miR-1909	CLIP-seq
MIRT888702	hsa-miR-198	CLIP-seq
MIRT888703	hsa-miR-24	CLIP-seq
MIRT888704	hsa-miR-3126-3p	CLIP-seq
MIRT888705	hsa-miR-3158-5p	CLIP-seq
MIRT888706	hsa-miR-3176	CLIP-seq
MIRT888707	hsa-miR-3184	CLIP-seq
MIRT888708	hsa-miR-3664-3p	CLIP-seq
MIRT888709	hsa-miR-3922-3p	CLIP-seq
MIRT888710	hsa-miR-423-5p	CLIP-seq
MIRT888711	hsa-miR-4436a	CLIP-seq
MIRT888712	hsa-miR-4437	CLIP-seq
MIRT888713	hsa-miR-4447	CLIP-seq
MIRT888714	hsa-miR-4472	CLIP-seq
MIRT888715	hsa-miR-4488	CLIP-seq
MIRT888717	hsa-miR-4685-5p	CLIP-seq
MIRT888718	hsa-miR-4697-5p	CLIP-seq
MIRT888719	hsa-miR-4701-5p	CLIP-seq
MIRT888720	hsa-miR-4728-5p	CLIP-seq
MIRT888722	hsa-miR-486-3p	CLIP-seq
MIRT888723	hsa-miR-588	CLIP-seq
MIRT888702	hsa-miR-198	CLIP-seq
MIRT888703	hsa-miR-24	CLIP-seq
MIRT888704	hsa-miR-3126-3p	CLIP-seq
MIRT888706	hsa-miR-3176	CLIP-seq
MIRT888708	hsa-miR-3664-3p	CLIP-seq
MIRT888709	hsa-miR-3922-3p	CLIP-seq
MIRT888711	hsa-miR-4436a	CLIP-seq
MIRT888712	hsa-miR-4437	CLIP-seq
MIRT888716	hsa-miR-4641	CLIP-seq
MIRT888717	hsa-miR-4685-5p	CLIP-seq
MIRT888719	hsa-miR-4701-5p	CLIP-seq
MIRT888723	hsa-miR-588	CLIP-seq
MIRT888724	hsa-miR-665	CLIP-seq
MIRT888702	hsa-miR-198	CLIP-seq
MIRT888703	hsa-miR-24	CLIP-seq
MIRT888708	hsa-miR-3664-3p	CLIP-seq
MIRT888711	hsa-miR-4436a	CLIP-seq
MIRT888712	hsa-miR-4437	CLIP-seq
MIRT888716	hsa-miR-4641	CLIP-seq
MIRT888717	hsa-miR-4685-5p	CLIP-seq
MIRT888724	hsa-miR-665	CLIP-seq

Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005739	Component	Mitochondrion	NAS	28893745
GO:0005758	Component	Mitochondrial intermembrane space	IBA
GO:0005758	Component	Mitochondrial intermembrane space	IEA
GO:0045333	Process	Cellular respiration	IBA

MIM	HGNC	e!Ensembl
616978	17840	ENSG00000125611

Q9BSY4

Protein name

Coiled-coil-helix-coiled-coil-helix domain-containing protein 5

PDB

2LQL

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16860	CX9C	5 → 49	CHCH-CHCH-like Cx9C, IMS import disulfide relay-system,	Domain

Sequence

MQAALEVTARYCGRELEQYGQCVAAKPESWQRDCHYLKMSIAQCTSSHPIIRQIRQACAQ
PFEAFEECLRQNEAAVGNCAEHMRRFLQCAEQVQPPRSPATVEAQPLPAS

Sequence length

110

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
AMENORRHEA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DENTAL CARIES	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DENTAL ENAMEL HYPOPLASIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TOOTH AGENESIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (9)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Carcinoma of lung	Lung carcinoma	BEFREE	31221176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	28893745	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypertensive disease	Hypertension	BEFREE	28893745		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung Neoplasms	BEFREE	31221176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	31221176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29371680, 31221176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	31221176		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	28893745		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	28893745	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

CHCHD5 (coiled-coil-helix-coiled-coil-helix domain containing 5)