Gene Gene information from NCBI Gene database.
Entrez ID 83988
Gene name Neurocalcin delta
Gene symbol NCALD
Synonyms (NCBI Gene)
-
Chromosome 8
Chromosome location 8q22.3
Summary This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; howeve
miRNA miRNA information provided by mirtarbase database.
283
miRTarBase ID miRNA Experiments Reference
MIRT448662 hsa-miR-203a-3p PAR-CLIP 22100165
MIRT448662 hsa-miR-203a-3p PAR-CLIP 22100165
MIRT448661 hsa-miR-32-3p PAR-CLIP 22100165
MIRT448660 hsa-miR-4635 PAR-CLIP 22100165
MIRT448659 hsa-miR-569 PAR-CLIP 22100165
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
GO ID Ontology Definition Evidence Reference
GO:0003073 Process Regulation of systemic arterial blood pressure IEA
GO:0003779 Function Actin binding IBA
GO:0003779 Function Actin binding IDA 11964161
GO:0003779 Function Actin binding IEA
GO:0005509 Function Calcium ion binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606722 7655 ENSG00000104490
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P61601
Protein name Neurocalcin-delta
Protein function May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13833 EF-hand_8 39 90 EF-hand domain pair Domain
PF13499 EF-hand_7 98 174 EF-hand domain pair Domain
PF13202 EF-hand_5 149 173 EF hand Domain
Tissue specificity TISSUE SPECIFICITY: Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.
Sequence
Sequence length 193
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Olfactory transduction   Activation of Ca-permeable Kainate Receptor
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
11
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ASTHMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CEREBRAL AMYLOID ANGIOPATHY GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CHRONIC OBSTRUCTIVE PULMONARY DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Carcinoma Ovarian Epithelial Epithelial ovarian carcinoma Pubtator 32228639 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma, Ovarian Epithelial Ovarian Epithelial carcinoma BEFREE 31109331
★☆☆☆☆
Found in Text Mining only
Cardiovascular Diseases Cardiovascular Diseases GWASCAT_DG 30595370
★☆☆☆☆
Found in Text Mining only
Celiac Disease Celiac disease BEFREE 26123480
★☆☆☆☆
Found in Text Mining only
Celiac Disease Celiac disease Pubtator 26123480 Associate
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 35014676 Associate
★☆☆☆☆
Found in Text Mining only
Diabetic Nephropathy Diabetic Nephropathy BEFREE 17671797
★☆☆☆☆
Found in Text Mining only
Diabetic Nephropathy Diabetic Nephropathy LHGDN 17671797
★☆☆☆☆
Found in Text Mining only
Leukemia Myeloid Acute Myeloid leukemia Pubtator 31109331 Associate
★☆☆☆☆
Found in Text Mining only
Leukemia, Myelocytic, Acute Leukemia BEFREE 31109331
★☆☆☆☆
Found in Text Mining only