LONP2 (lon peptidase 2, peroxisomal)

Gene

• Entrez ID: 83752
• Gene name: Lon peptidase 2, peroxisomal
• Gene symbol: LONP2
• Synonyms (NCBI Gene): LONP, LONPL, PLON, PSLON
• Chromosome: 16
• Chromosome location: 16q12.1
• Summary: In human, peroxisomes function primarily to catalyze fatty acid beta-oxidation and, as a by-product, produce hydrogen peroxide and superoxide. The protein encoded by this gene is an ATP-dependent protease that likely plays a role in maintaining overall pe

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020862	hsa-miR-155-5p	Proteomics	18668040
MIRT023972	hsa-miR-1-3p	Proteomics	18668040
MIRT044448	hsa-miR-320a	CLASH	23622248
MIRT041601	hsa-miR-193b-3p	CLASH	23622248
MIRT038688	hsa-miR-30c-2-3p	CLASH	23622248
MIRT037968	hsa-miR-505-5p	CLASH	23622248
MIRT616770	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT616769	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT616768	hsa-miR-3135b	HITS-CLIP	23824327
MIRT616770	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT616769	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT616768	hsa-miR-3135b	HITS-CLIP	23824327
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	23824327
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	27418678
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	27418678
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	27418678
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	27418678
MIRT616770	hsa-miR-22-3p	HITS-CLIP	27418678
MIRT616768	hsa-miR-3135b	HITS-CLIP	27418678
MIRT616768	hsa-miR-3135b	HITS-CLIP	27418678
MIRT616768	hsa-miR-3135b	HITS-CLIP	27418678
MIRT616768	hsa-miR-3135b	HITS-CLIP	27418678
MIRT616769	hsa-miR-3692-5p	HITS-CLIP	27418678
MIRT616770	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT616769	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT616768	hsa-miR-3135b	HITS-CLIP	23824327
MIRT616770	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT616769	hsa-miR-3692-5p	HITS-CLIP	23824327
MIRT616768	hsa-miR-3135b	HITS-CLIP	23824327
MIRT616767	hsa-miR-1287-5p	HITS-CLIP	23824327
MIRT1114565	hsa-miR-103a	CLIP-seq
MIRT1114566	hsa-miR-106a	CLIP-seq
MIRT1114567	hsa-miR-106b	CLIP-seq
MIRT1114568	hsa-miR-107	CLIP-seq
MIRT1114569	hsa-miR-1200	CLIP-seq
MIRT1114570	hsa-miR-122	CLIP-seq
MIRT1114571	hsa-miR-1245b-3p	CLIP-seq
MIRT1114572	hsa-miR-1284	CLIP-seq
MIRT1114573	hsa-miR-1287	CLIP-seq
MIRT1114574	hsa-miR-1292	CLIP-seq
MIRT1114575	hsa-miR-1299	CLIP-seq
MIRT1114576	hsa-miR-1303	CLIP-seq
MIRT1114577	hsa-miR-1306	CLIP-seq
MIRT1114578	hsa-miR-130a	CLIP-seq
MIRT1114579	hsa-miR-130b	CLIP-seq
MIRT1114580	hsa-miR-146a	CLIP-seq
MIRT1114581	hsa-miR-146b-5p	CLIP-seq
MIRT1114582	hsa-miR-150	CLIP-seq
MIRT1114583	hsa-miR-17	CLIP-seq
MIRT1114584	hsa-miR-20a	CLIP-seq
MIRT1114585	hsa-miR-20b	CLIP-seq
MIRT1114586	hsa-miR-214	CLIP-seq
MIRT1114587	hsa-miR-219-2-3p	CLIP-seq
MIRT1114588	hsa-miR-219-5p	CLIP-seq
MIRT1114589	hsa-miR-296-3p	CLIP-seq
MIRT1114590	hsa-miR-2964a-3p	CLIP-seq
MIRT1114591	hsa-miR-301a	CLIP-seq
MIRT1114592	hsa-miR-301b	CLIP-seq
MIRT1114593	hsa-miR-302a	CLIP-seq
MIRT1114594	hsa-miR-302b	CLIP-seq
MIRT1114595	hsa-miR-302c	CLIP-seq
MIRT1114596	hsa-miR-302d	CLIP-seq
MIRT1114597	hsa-miR-302e	CLIP-seq
MIRT1114598	hsa-miR-3122	CLIP-seq
MIRT1114599	hsa-miR-3124-3p	CLIP-seq
MIRT1114600	hsa-miR-3140-5p	CLIP-seq
MIRT1114601	hsa-miR-3146	CLIP-seq
MIRT1114602	hsa-miR-3157-5p	CLIP-seq
MIRT1114603	hsa-miR-3180-5p	CLIP-seq
MIRT1114604	hsa-miR-3182	CLIP-seq
MIRT1114605	hsa-miR-3187-3p	CLIP-seq
MIRT1114606	hsa-miR-33a	CLIP-seq
MIRT1114607	hsa-miR-33b	CLIP-seq
MIRT1114608	hsa-miR-3545-3p	CLIP-seq
MIRT1114609	hsa-miR-3609	CLIP-seq
MIRT1114610	hsa-miR-3619-5p	CLIP-seq
MIRT1114611	hsa-miR-3622b-5p	CLIP-seq
MIRT1114612	hsa-miR-3652	CLIP-seq
MIRT1114613	hsa-miR-3659	CLIP-seq
MIRT1114614	hsa-miR-3666	CLIP-seq
MIRT1114615	hsa-miR-3685	CLIP-seq
MIRT1114616	hsa-miR-372	CLIP-seq
MIRT1114617	hsa-miR-373	CLIP-seq
MIRT1114618	hsa-miR-384	CLIP-seq
MIRT1114619	hsa-miR-3913-5p	CLIP-seq
MIRT1114620	hsa-miR-3934	CLIP-seq
MIRT1114621	hsa-miR-3944-5p	CLIP-seq
MIRT1114622	hsa-miR-3945	CLIP-seq
MIRT1114623	hsa-miR-423-3p	CLIP-seq
MIRT1114624	hsa-miR-4251	CLIP-seq
MIRT1114625	hsa-miR-4253	CLIP-seq
MIRT1114626	hsa-miR-4263	CLIP-seq
MIRT1114627	hsa-miR-4267	CLIP-seq
MIRT1114628	hsa-miR-4293	CLIP-seq
MIRT1114629	hsa-miR-4295	CLIP-seq
MIRT1114630	hsa-miR-4307	CLIP-seq
MIRT1114631	hsa-miR-431	CLIP-seq
MIRT1114632	hsa-miR-4430	CLIP-seq
MIRT1114633	hsa-miR-4435	CLIP-seq
MIRT1114634	hsa-miR-4438	CLIP-seq
MIRT1114635	hsa-miR-4471	CLIP-seq
MIRT1114636	hsa-miR-450b-3p	CLIP-seq
MIRT1114637	hsa-miR-452	CLIP-seq
MIRT1114638	hsa-miR-4530	CLIP-seq
MIRT1114639	hsa-miR-4539	CLIP-seq
MIRT1114640	hsa-miR-454	CLIP-seq
MIRT1114641	hsa-miR-4634	CLIP-seq
MIRT1114642	hsa-miR-4635	CLIP-seq
MIRT1114643	hsa-miR-4645-3p	CLIP-seq
MIRT1114644	hsa-miR-4652-3p	CLIP-seq
MIRT1114645	hsa-miR-4658	CLIP-seq
MIRT1114646	hsa-miR-4661-3p	CLIP-seq
MIRT1114647	hsa-miR-4663	CLIP-seq
MIRT1114648	hsa-miR-4676-3p	CLIP-seq
MIRT1114649	hsa-miR-4676-5p	CLIP-seq
MIRT1114650	hsa-miR-4680-5p	CLIP-seq
MIRT1114651	hsa-miR-4685-5p	CLIP-seq
MIRT1114652	hsa-miR-4691-3p	CLIP-seq
MIRT1114653	hsa-miR-4693-5p	CLIP-seq
MIRT1114654	hsa-miR-4701-5p	CLIP-seq
MIRT1114655	hsa-miR-4704-5p	CLIP-seq
MIRT1114656	hsa-miR-4717-3p	CLIP-seq
MIRT1114657	hsa-miR-4722-5p	CLIP-seq
MIRT1114658	hsa-miR-4755-3p	CLIP-seq
MIRT1114659	hsa-miR-4758-5p	CLIP-seq
MIRT1114660	hsa-miR-4764-5p	CLIP-seq
MIRT1114661	hsa-miR-4782-3p	CLIP-seq
MIRT1114662	hsa-miR-4782-5p	CLIP-seq
MIRT1114663	hsa-miR-4796-3p	CLIP-seq
MIRT1114664	hsa-miR-4796-5p	CLIP-seq
MIRT1114665	hsa-miR-5095	CLIP-seq
MIRT1114666	hsa-miR-511	CLIP-seq
MIRT1114667	hsa-miR-512-3p	CLIP-seq
MIRT1114668	hsa-miR-516b	CLIP-seq
MIRT1114669	hsa-miR-519d	CLIP-seq
MIRT1114670	hsa-miR-520a-3p	CLIP-seq
MIRT1114671	hsa-miR-520b	CLIP-seq
MIRT1114672	hsa-miR-520c-3p	CLIP-seq
MIRT1114673	hsa-miR-520d-3p	CLIP-seq
MIRT1114674	hsa-miR-520e	CLIP-seq
MIRT1114675	hsa-miR-520g	CLIP-seq
MIRT1114676	hsa-miR-520h	CLIP-seq
MIRT1114677	hsa-miR-548ah	CLIP-seq
MIRT1114678	hsa-miR-548s	CLIP-seq
MIRT1114679	hsa-miR-552	CLIP-seq
MIRT1114680	hsa-miR-556-3p	CLIP-seq
MIRT1114681	hsa-miR-574-5p	CLIP-seq
MIRT1114682	hsa-miR-575	CLIP-seq
MIRT1114683	hsa-miR-576-5p	CLIP-seq
MIRT1114684	hsa-miR-588	CLIP-seq
MIRT1114685	hsa-miR-589	CLIP-seq
MIRT1114686	hsa-miR-601	CLIP-seq
MIRT1114687	hsa-miR-619	CLIP-seq
MIRT1114688	hsa-miR-627	CLIP-seq
MIRT1114689	hsa-miR-635	CLIP-seq
MIRT1114690	hsa-miR-648	CLIP-seq
MIRT1114691	hsa-miR-652	CLIP-seq
MIRT1114692	hsa-miR-720	CLIP-seq
MIRT1114693	hsa-miR-761	CLIP-seq
MIRT1114694	hsa-miR-769-3p	CLIP-seq
MIRT1114695	hsa-miR-876-3p	CLIP-seq
MIRT1114696	hsa-miR-922	CLIP-seq
MIRT1114697	hsa-miR-93	CLIP-seq
MIRT1114574	hsa-miR-1292	CLIP-seq
MIRT2032228	hsa-miR-1297	CLIP-seq
MIRT2032229	hsa-miR-1343	CLIP-seq
MIRT2032230	hsa-miR-26a	CLIP-seq
MIRT2032231	hsa-miR-26b	CLIP-seq
MIRT1114589	hsa-miR-296-3p	CLIP-seq
MIRT2032232	hsa-miR-3117-3p	CLIP-seq
MIRT1114598	hsa-miR-3122	CLIP-seq
MIRT1114599	hsa-miR-3124-3p	CLIP-seq
MIRT1114601	hsa-miR-3146	CLIP-seq
MIRT1114603	hsa-miR-3180-5p	CLIP-seq
MIRT2032233	hsa-miR-361-5p	CLIP-seq
MIRT2032234	hsa-miR-3619-3p	CLIP-seq
MIRT2032235	hsa-miR-3663-3p	CLIP-seq
MIRT2032236	hsa-miR-3674	CLIP-seq
MIRT2032237	hsa-miR-370	CLIP-seq
MIRT1114619	hsa-miR-3913-5p	CLIP-seq
MIRT2032238	hsa-miR-3937	CLIP-seq
MIRT1114624	hsa-miR-4251	CLIP-seq
MIRT1114627	hsa-miR-4267	CLIP-seq
MIRT2032239	hsa-miR-4269	CLIP-seq
MIRT1114628	hsa-miR-4293	CLIP-seq
MIRT2032240	hsa-miR-4324	CLIP-seq
MIRT2032241	hsa-miR-4328	CLIP-seq
MIRT1114634	hsa-miR-4438	CLIP-seq
MIRT2032242	hsa-miR-4465	CLIP-seq
MIRT1114635	hsa-miR-4471	CLIP-seq
MIRT1114636	hsa-miR-450b-3p	CLIP-seq
MIRT1114643	hsa-miR-4645-3p	CLIP-seq
MIRT1114646	hsa-miR-4661-3p	CLIP-seq
MIRT1114651	hsa-miR-4685-5p	CLIP-seq
MIRT1114660	hsa-miR-4764-5p	CLIP-seq
MIRT2032243	hsa-miR-509-3p	CLIP-seq
MIRT1114665	hsa-miR-5095	CLIP-seq
MIRT1114666	hsa-miR-511	CLIP-seq
MIRT2032244	hsa-miR-562	CLIP-seq
MIRT2032245	hsa-miR-580	CLIP-seq
MIRT1114694	hsa-miR-769-3p	CLIP-seq
MIRT2032246	hsa-miR-890	CLIP-seq
MIRT2262851	hsa-miR-103b	CLIP-seq
MIRT1114566	hsa-miR-106a	CLIP-seq
MIRT1114567	hsa-miR-106b	CLIP-seq
MIRT1114569	hsa-miR-1200	CLIP-seq
MIRT1114570	hsa-miR-122	CLIP-seq
MIRT2262852	hsa-miR-1224-3p	CLIP-seq
MIRT2262853	hsa-miR-1234	CLIP-seq
MIRT2262854	hsa-miR-1255a	CLIP-seq
MIRT2262855	hsa-miR-1255b	CLIP-seq
MIRT1114573	hsa-miR-1287	CLIP-seq
MIRT2262856	hsa-miR-1290	CLIP-seq
MIRT1114575	hsa-miR-1299	CLIP-seq
MIRT2032229	hsa-miR-1343	CLIP-seq
MIRT1114580	hsa-miR-146a	CLIP-seq
MIRT1114581	hsa-miR-146b-5p	CLIP-seq
MIRT1114582	hsa-miR-150	CLIP-seq
MIRT1114583	hsa-miR-17	CLIP-seq
MIRT2262857	hsa-miR-1915	CLIP-seq
MIRT2262858	hsa-miR-196a	CLIP-seq
MIRT2262859	hsa-miR-196b	CLIP-seq
MIRT1114584	hsa-miR-20a	CLIP-seq
MIRT1114585	hsa-miR-20b	CLIP-seq
MIRT1114586	hsa-miR-214	CLIP-seq
MIRT2262860	hsa-miR-216a	CLIP-seq
MIRT2262861	hsa-miR-216b	CLIP-seq
MIRT1114589	hsa-miR-296-3p	CLIP-seq
MIRT1114593	hsa-miR-302a	CLIP-seq
MIRT1114594	hsa-miR-302b	CLIP-seq
MIRT1114595	hsa-miR-302c	CLIP-seq
MIRT1114596	hsa-miR-302d	CLIP-seq
MIRT1114597	hsa-miR-302e	CLIP-seq
MIRT1114599	hsa-miR-3124-3p	CLIP-seq
MIRT1114600	hsa-miR-3140-5p	CLIP-seq
MIRT1114601	hsa-miR-3146	CLIP-seq
MIRT2262862	hsa-miR-3156-3p	CLIP-seq
MIRT2262863	hsa-miR-3163	CLIP-seq
MIRT2262864	hsa-miR-3167	CLIP-seq
MIRT1114603	hsa-miR-3180-5p	CLIP-seq
MIRT1114604	hsa-miR-3182	CLIP-seq
MIRT2262865	hsa-miR-323b-3p	CLIP-seq
MIRT2262866	hsa-miR-331-5p	CLIP-seq
MIRT2262867	hsa-miR-340	CLIP-seq
MIRT1114609	hsa-miR-3609	CLIP-seq
MIRT2032233	hsa-miR-361-5p	CLIP-seq
MIRT1114610	hsa-miR-3619-5p	CLIP-seq
MIRT1114615	hsa-miR-3685	CLIP-seq
MIRT2032237	hsa-miR-370	CLIP-seq
MIRT1114616	hsa-miR-372	CLIP-seq
MIRT1114617	hsa-miR-373	CLIP-seq
MIRT2262868	hsa-miR-376a	CLIP-seq
MIRT2262869	hsa-miR-376b	CLIP-seq
MIRT2262870	hsa-miR-376c	CLIP-seq
MIRT1114618	hsa-miR-384	CLIP-seq
MIRT2262871	hsa-miR-3918	CLIP-seq
MIRT2262872	hsa-miR-3927	CLIP-seq
MIRT1114620	hsa-miR-3934	CLIP-seq
MIRT2032238	hsa-miR-3937	CLIP-seq
MIRT1114624	hsa-miR-4251	CLIP-seq
MIRT1114626	hsa-miR-4263	CLIP-seq
MIRT1114627	hsa-miR-4267	CLIP-seq
MIRT2032239	hsa-miR-4269	CLIP-seq
MIRT2262873	hsa-miR-4286	CLIP-seq
MIRT1114628	hsa-miR-4293	CLIP-seq
MIRT2262874	hsa-miR-4301	CLIP-seq
MIRT2262875	hsa-miR-4303	CLIP-seq
MIRT1114630	hsa-miR-4307	CLIP-seq
MIRT2032240	hsa-miR-4324	CLIP-seq
MIRT2032241	hsa-miR-4328	CLIP-seq
MIRT1114634	hsa-miR-4438	CLIP-seq
MIRT2262876	hsa-miR-4514	CLIP-seq
MIRT1114637	hsa-miR-452	CLIP-seq
MIRT1114638	hsa-miR-4530	CLIP-seq
MIRT1114641	hsa-miR-4634	CLIP-seq
MIRT2262877	hsa-miR-4640-5p	CLIP-seq
MIRT1114643	hsa-miR-4645-3p	CLIP-seq
MIRT2262878	hsa-miR-4649-3p	CLIP-seq
MIRT1114644	hsa-miR-4652-3p	CLIP-seq
MIRT1114646	hsa-miR-4661-3p	CLIP-seq
MIRT1114647	hsa-miR-4663	CLIP-seq
MIRT1114648	hsa-miR-4676-3p	CLIP-seq
MIRT1114651	hsa-miR-4685-5p	CLIP-seq
MIRT2262879	hsa-miR-4690-3p	CLIP-seq
MIRT2262880	hsa-miR-4692	CLIP-seq
MIRT1114653	hsa-miR-4693-5p	CLIP-seq
MIRT2262881	hsa-miR-4698	CLIP-seq
MIRT1114655	hsa-miR-4704-5p	CLIP-seq
MIRT1114656	hsa-miR-4717-3p	CLIP-seq
MIRT1114657	hsa-miR-4722-5p	CLIP-seq
MIRT2262882	hsa-miR-4726-3p	CLIP-seq
MIRT2262883	hsa-miR-4726-5p	CLIP-seq
MIRT2262884	hsa-miR-4742-5p	CLIP-seq
MIRT2262885	hsa-miR-4772-3p	CLIP-seq
MIRT1114662	hsa-miR-4782-5p	CLIP-seq
MIRT1114663	hsa-miR-4796-3p	CLIP-seq
MIRT2262886	hsa-miR-485-3p	CLIP-seq
MIRT2262887	hsa-miR-490-5p	CLIP-seq
MIRT2262888	hsa-miR-499a-5p	CLIP-seq
MIRT2032243	hsa-miR-509-3p	CLIP-seq
MIRT1114665	hsa-miR-5095	CLIP-seq
MIRT1114666	hsa-miR-511	CLIP-seq
MIRT1114667	hsa-miR-512-3p	CLIP-seq
MIRT1114668	hsa-miR-516b	CLIP-seq
MIRT1114669	hsa-miR-519d	CLIP-seq
MIRT1114670	hsa-miR-520a-3p	CLIP-seq
MIRT1114671	hsa-miR-520b	CLIP-seq
MIRT1114672	hsa-miR-520c-3p	CLIP-seq
MIRT1114673	hsa-miR-520d-3p	CLIP-seq
MIRT1114674	hsa-miR-520e	CLIP-seq
MIRT1114675	hsa-miR-520g	CLIP-seq
MIRT1114676	hsa-miR-520h	CLIP-seq
MIRT1114677	hsa-miR-548ah	CLIP-seq
MIRT1114679	hsa-miR-552	CLIP-seq
MIRT1114680	hsa-miR-556-3p	CLIP-seq
MIRT2032245	hsa-miR-580	CLIP-seq
MIRT1114685	hsa-miR-589	CLIP-seq
MIRT2262889	hsa-miR-617	CLIP-seq
MIRT2262890	hsa-miR-618	CLIP-seq
MIRT2262891	hsa-miR-665	CLIP-seq
MIRT1114693	hsa-miR-761	CLIP-seq
MIRT2262892	hsa-miR-802	CLIP-seq
MIRT2262893	hsa-miR-876-5p	CLIP-seq
MIRT2032246	hsa-miR-890	CLIP-seq
MIRT1114697	hsa-miR-93	CLIP-seq
MIRT1114627	hsa-miR-4267	CLIP-seq
MIRT1114641	hsa-miR-4634	CLIP-seq
MIRT2262885	hsa-miR-4772-3p	CLIP-seq
MIRT2262857	hsa-miR-1915	CLIP-seq
MIRT2453192	hsa-miR-3149	CLIP-seq
MIRT2453193	hsa-miR-3170	CLIP-seq
MIRT2453194	hsa-miR-3651	CLIP-seq
MIRT2032236	hsa-miR-3674	CLIP-seq
MIRT2453195	hsa-miR-4662a-5p	CLIP-seq
MIRT2453196	hsa-miR-4715-3p	CLIP-seq
MIRT2453197	hsa-miR-4735-5p	CLIP-seq
MIRT2453198	hsa-miR-4775	CLIP-seq
MIRT2453199	hsa-miR-590-3p	CLIP-seq
MIRT1114566	hsa-miR-106a	CLIP-seq
MIRT1114567	hsa-miR-106b	CLIP-seq
MIRT2562194	hsa-miR-1227	CLIP-seq
MIRT1114573	hsa-miR-1287	CLIP-seq
MIRT1114577	hsa-miR-1306	CLIP-seq
MIRT2032229	hsa-miR-1343	CLIP-seq
MIRT1114582	hsa-miR-150	CLIP-seq
MIRT2562195	hsa-miR-1587	CLIP-seq
MIRT1114583	hsa-miR-17	CLIP-seq
MIRT1114584	hsa-miR-20a	CLIP-seq
MIRT1114585	hsa-miR-20b	CLIP-seq
MIRT2562196	hsa-miR-2115	CLIP-seq
MIRT1114588	hsa-miR-219-5p	CLIP-seq
MIRT2562197	hsa-miR-2681	CLIP-seq
MIRT2562198	hsa-miR-300	CLIP-seq
MIRT1114593	hsa-miR-302a	CLIP-seq
MIRT1114594	hsa-miR-302b	CLIP-seq
MIRT1114595	hsa-miR-302c	CLIP-seq
MIRT1114596	hsa-miR-302d	CLIP-seq
MIRT1114597	hsa-miR-302e	CLIP-seq
MIRT2453192	hsa-miR-3149	CLIP-seq
MIRT2562199	hsa-miR-3154	CLIP-seq
MIRT2562200	hsa-miR-3179	CLIP-seq
MIRT1114605	hsa-miR-3187-3p	CLIP-seq
MIRT1114608	hsa-miR-3545-3p	CLIP-seq
MIRT2562201	hsa-miR-3616-3p	CLIP-seq
MIRT2562202	hsa-miR-3653	CLIP-seq
MIRT2562203	hsa-miR-3656	CLIP-seq
MIRT2032236	hsa-miR-3674	CLIP-seq
MIRT1114616	hsa-miR-372	CLIP-seq
MIRT1114617	hsa-miR-373	CLIP-seq
MIRT2562204	hsa-miR-381	CLIP-seq
MIRT2032238	hsa-miR-3937	CLIP-seq
MIRT1114623	hsa-miR-423-3p	CLIP-seq
MIRT2562205	hsa-miR-4252	CLIP-seq
MIRT2032239	hsa-miR-4269	CLIP-seq
MIRT2262875	hsa-miR-4303	CLIP-seq
MIRT1114631	hsa-miR-431	CLIP-seq
MIRT2562206	hsa-miR-4310	CLIP-seq
MIRT1114633	hsa-miR-4435	CLIP-seq
MIRT2562207	hsa-miR-4437	CLIP-seq
MIRT2562208	hsa-miR-4446-3p	CLIP-seq
MIRT2262876	hsa-miR-4514	CLIP-seq
MIRT1114642	hsa-miR-4635	CLIP-seq
MIRT2262878	hsa-miR-4649-3p	CLIP-seq
MIRT2562209	hsa-miR-4674	CLIP-seq
MIRT1114650	hsa-miR-4680-5p	CLIP-seq
MIRT2262880	hsa-miR-4692	CLIP-seq
MIRT1114654	hsa-miR-4701-5p	CLIP-seq
MIRT2453196	hsa-miR-4715-3p	CLIP-seq
MIRT2562210	hsa-miR-4721	CLIP-seq
MIRT2562211	hsa-miR-4732-5p	CLIP-seq
MIRT2453197	hsa-miR-4735-5p	CLIP-seq
MIRT2262884	hsa-miR-4742-5p	CLIP-seq
MIRT2453198	hsa-miR-4775	CLIP-seq
MIRT1114661	hsa-miR-4782-3p	CLIP-seq
MIRT2562212	hsa-miR-4797-5p	CLIP-seq
MIRT1114666	hsa-miR-511	CLIP-seq
MIRT1114667	hsa-miR-512-3p	CLIP-seq
MIRT2562213	hsa-miR-516a-3p	CLIP-seq
MIRT1114669	hsa-miR-519d	CLIP-seq
MIRT1114670	hsa-miR-520a-3p	CLIP-seq
MIRT1114671	hsa-miR-520b	CLIP-seq
MIRT1114672	hsa-miR-520c-3p	CLIP-seq
MIRT1114673	hsa-miR-520d-3p	CLIP-seq
MIRT1114674	hsa-miR-520e	CLIP-seq
MIRT1114675	hsa-miR-520g	CLIP-seq
MIRT1114676	hsa-miR-520h	CLIP-seq
MIRT1114678	hsa-miR-548s	CLIP-seq
MIRT1114684	hsa-miR-588	CLIP-seq
MIRT2453199	hsa-miR-590-3p	CLIP-seq
MIRT1114689	hsa-miR-635	CLIP-seq
MIRT2562214	hsa-miR-642a	CLIP-seq
MIRT1114697	hsa-miR-93	CLIP-seq
MIRT1114573	hsa-miR-1287	CLIP-seq
MIRT1114577	hsa-miR-1306	CLIP-seq
MIRT2032229	hsa-miR-1343	CLIP-seq
MIRT2562195	hsa-miR-1587	CLIP-seq
MIRT2562196	hsa-miR-2115	CLIP-seq
MIRT1114588	hsa-miR-219-5p	CLIP-seq
MIRT2562197	hsa-miR-2681	CLIP-seq
MIRT2562198	hsa-miR-300	CLIP-seq
MIRT2453192	hsa-miR-3149	CLIP-seq
MIRT2453193	hsa-miR-3170	CLIP-seq
MIRT1114605	hsa-miR-3187-3p	CLIP-seq
MIRT1114608	hsa-miR-3545-3p	CLIP-seq
MIRT2562201	hsa-miR-3616-3p	CLIP-seq
MIRT2032236	hsa-miR-3674	CLIP-seq
MIRT2562204	hsa-miR-381	CLIP-seq
MIRT1114623	hsa-miR-423-3p	CLIP-seq
MIRT2562205	hsa-miR-4252	CLIP-seq
MIRT2032239	hsa-miR-4269	CLIP-seq
MIRT2262875	hsa-miR-4303	CLIP-seq
MIRT1114631	hsa-miR-431	CLIP-seq
MIRT2683998	hsa-miR-4423-5p	CLIP-seq
MIRT1114633	hsa-miR-4435	CLIP-seq
MIRT2562207	hsa-miR-4437	CLIP-seq
MIRT2562208	hsa-miR-4446-3p	CLIP-seq
MIRT2262876	hsa-miR-4514	CLIP-seq
MIRT1114642	hsa-miR-4635	CLIP-seq
MIRT2262878	hsa-miR-4649-3p	CLIP-seq
MIRT2683999	hsa-miR-4659a-5p	CLIP-seq
MIRT2684000	hsa-miR-4659b-5p	CLIP-seq
MIRT2562209	hsa-miR-4674	CLIP-seq
MIRT1114650	hsa-miR-4680-5p	CLIP-seq
MIRT2262880	hsa-miR-4692	CLIP-seq
MIRT1114654	hsa-miR-4701-5p	CLIP-seq
MIRT2453196	hsa-miR-4715-3p	CLIP-seq
MIRT2684001	hsa-miR-4716-5p	CLIP-seq
MIRT2562210	hsa-miR-4721	CLIP-seq
MIRT2562211	hsa-miR-4732-5p	CLIP-seq
MIRT2453197	hsa-miR-4735-5p	CLIP-seq
MIRT2262884	hsa-miR-4742-5p	CLIP-seq
MIRT2453198	hsa-miR-4775	CLIP-seq
MIRT2684002	hsa-miR-4776-3p	CLIP-seq
MIRT1114661	hsa-miR-4782-3p	CLIP-seq
MIRT2562212	hsa-miR-4797-5p	CLIP-seq
MIRT1114666	hsa-miR-511	CLIP-seq
MIRT2562213	hsa-miR-516a-3p	CLIP-seq
MIRT1114678	hsa-miR-548s	CLIP-seq
MIRT1114684	hsa-miR-588	CLIP-seq
MIRT2453199	hsa-miR-590-3p	CLIP-seq
MIRT1114689	hsa-miR-635	CLIP-seq
MIRT2562214	hsa-miR-642a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0002020	Function	Protease binding	IPI	22002062
GO:0004176	Function	ATP-dependent peptidase activity	IEA
GO:0004252	Function	Serine-type endopeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	18281296, 27173435, 28514442, 32296183, 33961781
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005777	Component	Peroxisome	IDA	14561759, 18281296, 22002062
GO:0005777	Component	Peroxisome	IEA
GO:0005782	Component	Peroxisomal matrix	IBA
GO:0005782	Component	Peroxisomal matrix	IEA
GO:0005782	Component	Peroxisomal matrix	TAS
GO:0005829	Component	Cytosol	TAS
GO:0006508	Process	Proteolysis	IEA
GO:0006515	Process	Protein quality control for misfolded or incompletely synthesized proteins	IEA
GO:0006625	Process	Protein targeting to peroxisome	IBA
GO:0006625	Process	Protein targeting to peroxisome	IMP	18281296
GO:0007031	Process	Peroxisome organization	NAS	14561759
GO:0008233	Function	Peptidase activity	IDA	18281296
GO:0008233	Function	Peptidase activity	IEA
GO:0008236	Function	Serine-type peptidase activity	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016485	Process	Protein processing	IBA
GO:0016485	Process	Protein processing	IEA
GO:0016485	Process	Protein processing	IMP	18281296
GO:0016558	Process	Protein import into peroxisome matrix	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0019899	Function	Enzyme binding	IPI	18281296
GO:0030163	Process	Protein catabolic process	IEA
GO:0031998	Process	Regulation of fatty acid beta-oxidation	IMP	22002062

Other IDs

• MIM: 617774
• HGNC: 20598
• e!Ensembl: ENSG00000102910

Protein

• UniProt ID: Q86WA8
• Protein name: Lon protease homolog 2, peroxisomal (EC 3.4.21.53) (Lon protease-like protein 2) (Lon protease 2) (Peroxisomal Lon protease) (pLon)
• Protein function: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates pero
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02190	LON_substr_bdg	12 → 220	ATP-dependent protease La (LON) substrate-binding domain	Family
  PF00004	AAA	371 → 512	ATPase family associated with various cellular activities (AAA)	Domain
  PF05362	Lon_C	628 → 837	Lon protease (S16) C-terminal proteolytic domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed, with high levels in the liver, kidney and pancreas. {ECO:0000269|PubMed:18281296}.
• Sequence:

  MSSVSPIQIPSRLPLLLTHEGVLLPGSTMRTSVDSARNLQLVRSRLLKGTSLQSTILGVI
  PNTPDPASDAQDLPPLHRIGTAALAVQVVGSNWPKPHYTLLITGLCRFQIVQVLKEKPYP
  IAEVEQLDRLEEFPNTCKMREELGELSEQFYKYAVQLVEMLDMSVPAVAKLRRLLDSLPR
  EALPDILTSIIRTSNKEKLQILDAVSLEERFKMTIPLLVRQIEGLKLLQKTRKPKQDDDK
  RVIAIRPIRRITHISGTLEDEDEDEDNDDIVMLEKKIRTSSMPEQAHKVCVKEIKRLKKM
  PQSMPEYALTRNYLELMVELPWNKSTTDRLDIRAARILLDNDHYAMEKLKKRVLEYLAVR
  QLKNNLKGPILCFVGPPGVGKTSVGRSVAKTLGREFHRIALGGVCDQSDIRGHRRTYVGS
  MPGRIINGLKTVGVNNPVFLLDEVDKLGKSLQGDPAAALLEVLDPEQNHNFTDHYLNVAF
  DLSQVLFIATANTTATIPAALLDRMEIIQVPGYTQEEKIEIAHRHLIPKQLEQHGLTPQQ
  IQIPQVTTLDIITRYTREAGVRSLDRKLGAICRAVAVKVAEGQHKEAKLDRSDVTEREGC
  REHILEDEKPESISDTTDLALPPEMPILIDFHALKDILGPPMYEMEVSQRLSQPGVAIGL
  AWTPLGGEIMFVEASRMDGEGQLTLTGQLGDVMKESAHLAISWLRSNAKKYQLTNAFGSF
  DLLDNTDIHLHFPAGAVTKDGPSAGVTIVTCLASLFSGRLVRSDVAMTGEITLRGLVLPV
  GGIKDKVLAAHRAGLKQVIIPRRNEKDLEGIPGNVRQDLSFVTASCLDEVLNAAFDGGFT
  VKTRPGLLNSKL

• Sequence length: 852

Pathways

Reactome:

Peroxisomal protein import

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BURATTI-HAREL SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Squamous Cell	Squamous cell carcinoma	Pubtator	35768804	Associate	★☆☆☆☆ Found in Text Mining only
cervical cancer	Cervical Cancer	BEFREE	29502128		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	29502128		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29502128		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	29502128		★☆☆☆☆ Found in Text Mining only
Osteoglophonic dwarfism	Osteoglophonic dwarfism	Pubtator	34589382	Stimulate	★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	35358000	Associate	★☆☆☆☆ Found in Text Mining only