Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	83719
Gene name	Yippee like 3
Gene symbol	YPEL3
Synonyms (NCBI Gene)	-
Chromosome	16
Chromosome location	16p11.2

Show/Hide all (59)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017916	hsa-miR-335-5p	Microarray	18185580
MIRT1499474	hsa-miR-1184	CLIP-seq
MIRT1499475	hsa-miR-1205	CLIP-seq
MIRT1499476	hsa-miR-128	CLIP-seq
MIRT1499477	hsa-miR-148a	CLIP-seq
MIRT1499478	hsa-miR-148b	CLIP-seq
MIRT1499479	hsa-miR-152	CLIP-seq
MIRT1499480	hsa-miR-1909	CLIP-seq
MIRT1499481	hsa-miR-1972	CLIP-seq
MIRT1499482	hsa-miR-198	CLIP-seq
MIRT1499483	hsa-miR-2278	CLIP-seq
MIRT1499484	hsa-miR-27a	CLIP-seq
MIRT1499485	hsa-miR-27b	CLIP-seq
MIRT1499486	hsa-miR-28-5p	CLIP-seq
MIRT1499487	hsa-miR-3139	CLIP-seq
MIRT1499488	hsa-miR-3158-5p	CLIP-seq
MIRT1499489	hsa-miR-3163	CLIP-seq
MIRT1499490	hsa-miR-3649	CLIP-seq
MIRT1499491	hsa-miR-3909	CLIP-seq
MIRT1499492	hsa-miR-3921	CLIP-seq
MIRT1499493	hsa-miR-3974	CLIP-seq
MIRT1499494	hsa-miR-4283	CLIP-seq
MIRT1499495	hsa-miR-4287	CLIP-seq
MIRT1499496	hsa-miR-4468	CLIP-seq
MIRT1499497	hsa-miR-4633-3p	CLIP-seq
MIRT1499498	hsa-miR-4649-3p	CLIP-seq
MIRT1499499	hsa-miR-4653-5p	CLIP-seq
MIRT1499500	hsa-miR-4685-3p	CLIP-seq
MIRT1499501	hsa-miR-4700-3p	CLIP-seq
MIRT1499502	hsa-miR-4768-3p	CLIP-seq
MIRT1499503	hsa-miR-4800-3p	CLIP-seq
MIRT1499504	hsa-miR-520a-5p	CLIP-seq
MIRT1499505	hsa-miR-525-5p	CLIP-seq
MIRT1499506	hsa-miR-665	CLIP-seq
MIRT1499507	hsa-miR-708	CLIP-seq
MIRT1499508	hsa-miR-760	CLIP-seq
MIRT1499484	hsa-miR-27a	CLIP-seq
MIRT1499485	hsa-miR-27b	CLIP-seq
MIRT2150413	hsa-miR-3194-5p	CLIP-seq
MIRT2150414	hsa-miR-4722-5p	CLIP-seq
MIRT1499484	hsa-miR-27a	CLIP-seq
MIRT1499485	hsa-miR-27b	CLIP-seq
MIRT1499483	hsa-miR-2278	CLIP-seq
MIRT1499484	hsa-miR-27a	CLIP-seq
MIRT1499485	hsa-miR-27b	CLIP-seq
MIRT2664386	hsa-miR-2861	CLIP-seq
MIRT2664387	hsa-miR-3154	CLIP-seq
MIRT2664388	hsa-miR-3653	CLIP-seq
MIRT2664389	hsa-miR-3689a-3p	CLIP-seq
MIRT2664390	hsa-miR-3689c	CLIP-seq
MIRT2664391	hsa-miR-4456	CLIP-seq
MIRT1499496	hsa-miR-4468	CLIP-seq
MIRT2664392	hsa-miR-4512	CLIP-seq
MIRT2664393	hsa-miR-4728-5p	CLIP-seq
MIRT2664394	hsa-miR-513a-5p	CLIP-seq
MIRT2664395	hsa-miR-541	CLIP-seq
MIRT2664396	hsa-miR-555	CLIP-seq
MIRT2664397	hsa-miR-654-5p	CLIP-seq
MIRT2664398	hsa-miR-765	CLIP-seq

Show/Hide all (4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:2000774	Process	Positive regulation of cellular senescence	IDA	20388804

MIM	HGNC	e!Ensembl
609724	18327	ENSG00000090238

P61236

Protein name

Protein yippee-like 3

Protein function

Involved in proliferation and apoptosis in myeloid precursor cells.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03226	Yippee-Mis18	20 → 118	Yippee zinc-binding/DNA-binding /Mis18, centromere assembly	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:15556292}.

Sequence

MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCG
PAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD

Sequence length

119

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (12)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Adenocarcinoma	Adenocarcinoma	BEFREE	21267786		★★★★★ ★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	29988027		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	21671470, 34990474	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	21267786		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic Neoplasms	BEFREE	21267786		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	29988027	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	21267786		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	27400785		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	20388804, 21267786		★★★★★ ★☆☆☆☆ Found in Text Mining only
Oestrogen receptor positive breast cancer	Oestrogen Receptor Positive Breast Cancer	BEFREE	21671470		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	20388804	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	34715901	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

YPEL3 (yippee like 3)