SOX7 (SRY-box transcription factor 7)

Gene

• Entrez ID: 83595
• Gene name: SRY-box transcription factor 7
• Gene symbol: SOX7
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8p23.1
• Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after for

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT054539	hsa-miR-184	Flow, Luciferase reporter assay, qRT-PCR, Western blot	24558429
MIRT054539	hsa-miR-184	Flow, Luciferase reporter assay, qRT-PCR, Western blot	24558429
MIRT633798	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT633797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT633796	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT633795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633794	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT633793	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT633792	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT732359	hsa-miR-9-5p	Luciferase reporter assay, qRT-PCR, Western blot	28266181
MIRT732359	hsa-miR-9-5p	Luciferase reporter assay, qRT-PCR, Western blot	28266181
MIRT733997	hsa-miR-21-3p	Luciferase reporter assay, Northern blotting, qRT-PCR, Western blotting	32782620
MIRT633798	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT633797	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT633796	hsa-miR-6736-3p	HITS-CLIP	23824327
MIRT633795	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT633794	hsa-miR-6787-3p	HITS-CLIP	23824327
MIRT633793	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT633792	hsa-miR-5571-3p	HITS-CLIP	23824327
MIRT1380716	hsa-miR-122	CLIP-seq
MIRT1380717	hsa-miR-1229	CLIP-seq
MIRT1380718	hsa-miR-124	CLIP-seq
MIRT1380719	hsa-miR-1273e	CLIP-seq
MIRT1380720	hsa-miR-130a	CLIP-seq
MIRT1380721	hsa-miR-130b	CLIP-seq
MIRT1380722	hsa-miR-181a	CLIP-seq
MIRT1380723	hsa-miR-181b	CLIP-seq
MIRT1380724	hsa-miR-181c	CLIP-seq
MIRT1380725	hsa-miR-181d	CLIP-seq
MIRT1380726	hsa-miR-21	CLIP-seq
MIRT1380727	hsa-miR-301a	CLIP-seq
MIRT1380728	hsa-miR-301b	CLIP-seq
MIRT1380729	hsa-miR-3135b	CLIP-seq
MIRT1380730	hsa-miR-3164	CLIP-seq
MIRT1380731	hsa-miR-3178	CLIP-seq
MIRT1380732	hsa-miR-342-3p	CLIP-seq
MIRT1380733	hsa-miR-3613-3p	CLIP-seq
MIRT1380734	hsa-miR-3617	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT1380736	hsa-miR-3666	CLIP-seq
MIRT1380737	hsa-miR-3689a-5p	CLIP-seq
MIRT1380738	hsa-miR-3689b	CLIP-seq
MIRT1380739	hsa-miR-3689e	CLIP-seq
MIRT1380740	hsa-miR-3689f	CLIP-seq
MIRT1380741	hsa-miR-4262	CLIP-seq
MIRT1380742	hsa-miR-4295	CLIP-seq
MIRT1380743	hsa-miR-4428	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT1380746	hsa-miR-448	CLIP-seq
MIRT1380747	hsa-miR-4494	CLIP-seq
MIRT1380748	hsa-miR-4509	CLIP-seq
MIRT1380749	hsa-miR-452	CLIP-seq
MIRT1380750	hsa-miR-454	CLIP-seq
MIRT1380751	hsa-miR-4634	CLIP-seq
MIRT1380752	hsa-miR-4676-3p	CLIP-seq
MIRT1380753	hsa-miR-4677-3p	CLIP-seq
MIRT1380754	hsa-miR-4679	CLIP-seq
MIRT1380755	hsa-miR-4684-3p	CLIP-seq
MIRT1380756	hsa-miR-4712-3p	CLIP-seq
MIRT1380757	hsa-miR-4774-5p	CLIP-seq
MIRT1380758	hsa-miR-483-3p	CLIP-seq
MIRT1380759	hsa-miR-499a-5p	CLIP-seq
MIRT1380760	hsa-miR-506	CLIP-seq
MIRT1380761	hsa-miR-548ad	CLIP-seq
MIRT1380762	hsa-miR-590-5p	CLIP-seq
MIRT1380763	hsa-miR-641	CLIP-seq
MIRT1380764	hsa-miR-646	CLIP-seq
MIRT1380765	hsa-miR-654-3p	CLIP-seq
MIRT1380766	hsa-miR-664	CLIP-seq
MIRT1380767	hsa-miR-7	CLIP-seq
MIRT1380718	hsa-miR-124	CLIP-seq
MIRT2113993	hsa-miR-1909	CLIP-seq
MIRT2113994	hsa-miR-1976	CLIP-seq
MIRT2113995	hsa-miR-3614-3p	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT2113996	hsa-miR-3691-3p	CLIP-seq
MIRT2113997	hsa-miR-4279	CLIP-seq
MIRT2113998	hsa-miR-4297	CLIP-seq
MIRT1380743	hsa-miR-4428	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT2113999	hsa-miR-4675	CLIP-seq
MIRT2114000	hsa-miR-4716-5p	CLIP-seq
MIRT2114001	hsa-miR-4722-3p	CLIP-seq
MIRT2114002	hsa-miR-4741	CLIP-seq
MIRT1380760	hsa-miR-506	CLIP-seq
MIRT2114003	hsa-miR-5095	CLIP-seq
MIRT2114004	hsa-miR-562	CLIP-seq
MIRT1380716	hsa-miR-122	CLIP-seq
MIRT1380720	hsa-miR-130a	CLIP-seq
MIRT1380721	hsa-miR-130b	CLIP-seq
MIRT2336984	hsa-miR-151-3p	CLIP-seq
MIRT1380726	hsa-miR-21	CLIP-seq
MIRT2336985	hsa-miR-216a	CLIP-seq
MIRT1380727	hsa-miR-301a	CLIP-seq
MIRT1380728	hsa-miR-301b	CLIP-seq
MIRT1380729	hsa-miR-3135b	CLIP-seq
MIRT2336986	hsa-miR-3162-5p	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT1380736	hsa-miR-3666	CLIP-seq
MIRT1380737	hsa-miR-3689a-5p	CLIP-seq
MIRT1380738	hsa-miR-3689b	CLIP-seq
MIRT1380739	hsa-miR-3689e	CLIP-seq
MIRT1380740	hsa-miR-3689f	CLIP-seq
MIRT1380742	hsa-miR-4295	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT2336987	hsa-miR-4463	CLIP-seq
MIRT2336988	hsa-miR-4499	CLIP-seq
MIRT1380749	hsa-miR-452	CLIP-seq
MIRT1380750	hsa-miR-454	CLIP-seq
MIRT2336989	hsa-miR-4639-3p	CLIP-seq
MIRT2113999	hsa-miR-4675	CLIP-seq
MIRT1380752	hsa-miR-4676-3p	CLIP-seq
MIRT1380753	hsa-miR-4677-3p	CLIP-seq
MIRT1380754	hsa-miR-4679	CLIP-seq
MIRT1380755	hsa-miR-4684-3p	CLIP-seq
MIRT2336990	hsa-miR-4731-5p	CLIP-seq
MIRT2114002	hsa-miR-4741	CLIP-seq
MIRT2114003	hsa-miR-5095	CLIP-seq
MIRT2336991	hsa-miR-512-3p	CLIP-seq
MIRT1380762	hsa-miR-590-5p	CLIP-seq
MIRT2336992	hsa-miR-640	CLIP-seq
MIRT1380765	hsa-miR-654-3p	CLIP-seq
MIRT2113993	hsa-miR-1909	CLIP-seq
MIRT2113995	hsa-miR-3614-3p	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT1380716	hsa-miR-122	CLIP-seq
MIRT2460312	hsa-miR-203	CLIP-seq
MIRT1380729	hsa-miR-3135b	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT2336989	hsa-miR-4639-3p	CLIP-seq
MIRT2460313	hsa-miR-4653-3p	CLIP-seq
MIRT1380755	hsa-miR-4684-3p	CLIP-seq
MIRT2460314	hsa-miR-4694-3p	CLIP-seq
MIRT1380716	hsa-miR-122	CLIP-seq
MIRT1380720	hsa-miR-130a	CLIP-seq
MIRT1380721	hsa-miR-130b	CLIP-seq
MIRT2336985	hsa-miR-216a	CLIP-seq
MIRT1380727	hsa-miR-301a	CLIP-seq
MIRT1380728	hsa-miR-301b	CLIP-seq
MIRT1380729	hsa-miR-3135b	CLIP-seq
MIRT1380735	hsa-miR-3652	CLIP-seq
MIRT1380736	hsa-miR-3666	CLIP-seq
MIRT1380742	hsa-miR-4295	CLIP-seq
MIRT1380744	hsa-miR-4430	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT1380750	hsa-miR-454	CLIP-seq
MIRT1380745	hsa-miR-4438	CLIP-seq
MIRT2691791	hsa-miR-501-3p	CLIP-seq
MIRT2691792	hsa-miR-502-3p	CLIP-seq
MIRT2691793	hsa-miR-767-5p	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
FOS	Activation	22171135
JUN	Activation	22171135

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000976	Function	Transcription cis-regulatory region binding	IEA
GO:0000976	Function	Transcription cis-regulatory region binding	ISS
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IBA
GO:0001706	Process	Endoderm formation	IDA	18682240
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IDA	19108950
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	18682240, 19108950
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	18819930
GO:0005737	Component	Cytoplasm	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0009888	Process	Tissue development	IEA
GO:0030154	Process	Cell differentiation	IBA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	19108950
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0048646	Process	Anatomical structure formation involved in morphogenesis	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 612202
• HGNC: 18196
• e!Ensembl: ENSG00000171056

Protein

• UniProt ID: Q9BT81
• Protein name: Transcription factor SOX-7
• Protein function: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the surv
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00505	HMG_box	45 → 113	HMG (high mobility group) box	Domain
  PF12067	Sox17_18_mid	181 → 236	Sox 17/18 central domain	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermet
• Sequence:

  MASLLGAYPWPEGLECPALDAELSDGQSPPAVPRPPGDKGSESRIRRPMNAFMVWAKDER
  KRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK
  QAKRLCKRVDPGFLLSSLSRDQNALPEKRSGSRGALGEKEDRGEYSPGTALPSLRGCYHE
  GPAGGGGGGTPSSVDTYPYGLPTPPEMSPLDVLEPEQTFFSSPCQEEHGHPRRIPHLPGH
  PYSPEYAPSPLHCSHPLGSLALGQSPGVSMMSPVPGCPPSPAYYSPATYHPLHSNLQAHL
  GQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGAMALSGHVPVSQV
  TPTGPTETSLISVLADATATYYNSYSVS

• Sequence length: 388

Pathways

Reactome:

Deactivation of the beta-catenin transactivating complex

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BRAIN ANEURYSM	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CONGENITAL HEART DISEASE	—	ClinGen, Disgenet, GWAS catalog ClinGen, Disgenet, GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of urinary bladder	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROTIC DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SOX7-related disorder	Likely benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SYSTEMIC LUPUS ERYTHEMATOSUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TETRALOGY OF FALLOT	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	18819930		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of lung (disorder)	Lung adenocarcinoma	BEFREE	22777918		★☆☆☆☆ Found in Text Mining only
Bladder Neoplasm	Bladder Neoplasm	BEFREE	31773697		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	24012678, 25407488, 29757932, 31683462		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	19110721, 25407488, 29757932, 32238796	Associate	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	27188720	Inhibit	★☆☆☆☆ Found in Text Mining only
Campomelic Dysplasia	Campomelic dysplasia	Pubtator	36672963	Associate	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	27188720, 35222878	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	28586005		★☆☆☆☆ Found in Text Mining only
Carcinoma Endometrioid	Endometrioid carcinoma	Pubtator	23295859	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24558429, 25073511, 27697092	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24816720, 28586005	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	31773697		★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	23557216, 29231262, 31332289		★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	25297608		★☆☆☆☆ Found in Text Mining only
Cardiac defects	Cardiac Defects	BEFREE	24009689		★☆☆☆☆ Found in Text Mining only
Cardiomyopathy, Familial Idiopathic	Cardiomyopathy	BEFREE	24065215		★☆☆☆☆ Found in Text Mining only
Cardiovascular Abnormalities	Cardiovascular abnormalities	Pubtator	22929023	Associate	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Ulcerative colitis	Pubtator	30473377	Associate	★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	19108950, 22171135, 29552221		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	BEFREE	18819930		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal Neoplasms	LHGDN	18819930		★☆☆☆☆ Found in Text Mining only
Congenital diaphragmatic hernia	Congenital diaphragmatic hernia	BEFREE	22723016		★☆☆☆☆ Found in Text Mining only
Congenital Heart Defects	Congenital heart defects	BEFREE	24009689		★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29957056, 30506716		★☆☆☆☆ Found in Text Mining only
Coronary heart disease	Coronary Heart Disease	BEFREE	23345203, 28336264		★☆☆☆☆ Found in Text Mining only
Depressive Disorder	Major depressive disorder	Pubtator	35222878	Associate	★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	23295859		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	23295859	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy, Temporal Lobe	Epilepsy	BEFREE	30871773		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	25297608		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	27133048		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	27133048		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	29029454		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	29271996	Associate	★☆☆☆☆ Found in Text Mining only
Heart Defects Congenital	Congenital heart defect	Pubtator	24009689, 28336264	Associate	★☆☆☆☆ Found in Text Mining only
Heart Diseases	Heart disease	Pubtator	24009689	Associate	★☆☆☆☆ Found in Text Mining only
Hematologic Neoplasms	Hematologic Neoplasms	BEFREE	30554866		★☆☆☆☆ Found in Text Mining only
Hepatoblastoma	Hepatoblastoma	Pubtator	35645102	Inhibit	★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	25940713		★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	34768865	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	25940713		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	24558429, 24816720, 25073511, 27697092, 28586005		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	23557216	Inhibit	★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	28266181	Associate	★☆☆☆☆ Found in Text Mining only
Lymphatic Metastasis	Lymphatic metastasis	Pubtator	22777918, 32238796	Inhibit	★☆☆☆☆ Found in Text Mining only
Malignant Glioma	Glioma	BEFREE	29444818		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	24012678, 24288056, 25407488, 29757932, 31332289, 31683462		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	23295859		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	23557216, 24012678, 29231262, 31332289		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	25297608		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	11891528, 22703285, 30488457		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	24788044		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	31773697		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24788044, 25297608, 28586005, 29957056, 30066948, 31332289		★☆☆☆☆ Found in Text Mining only
MYELODYSPLASTIC SYNDROME	Myelodysplastic Syndrome	BEFREE	22706399, 30554866		★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Myelodysplastic syndrome	Pubtator	22706399	Associate	★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	30381030		★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	30381030	Associate	★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	18663352, 18819930, 22777918, 23557216, 24012678, 24288056, 24788044, 24816720, 25073511, 25297608, 25407488, 25940713, 26515813, 27044823, 28266739, 28586005, 29271996, 29444818, 29757932, 29957056, 30066948, 30473377, 31473269		★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	23557216, 28266181, 29123412, 30066948		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	BEFREE	26515813		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	25297608		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	25297608	Inhibit	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	32521870	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	28586005		★☆☆☆☆ Found in Text Mining only
Pancreatic Carcinoma	Pancreatic cancer	Pubtator	28586005	Inhibit	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	28586005	Inhibit	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	35222878	Associate	★☆☆☆☆ Found in Text Mining only
Pancreatitis	Pancreatitis	Pubtator	28586005	Associate	★☆☆☆☆ Found in Text Mining only
Pituitary Adenoma	Pituitary adenoma	BEFREE	30109259		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	11891528, 22703285, 30488457		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	18819930, 30488457		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	29957056		★☆☆☆☆ Found in Text Mining only
secondary acute myeloid leukemia	Myeloid leukemia	BEFREE	30554866		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	28266739		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of tongue	Tongue carcinoma	BEFREE	30008922		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	24788044		★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	31773697	Associate	★☆☆☆☆ Found in Text Mining only