Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	8208
Gene name	Chromatin assembly factor 1 subunit B
Gene symbol	CHAF1B
Synonyms (NCBI Gene)	CAF-1CAF-IP60CAF1CAF1ACAF1P60MPHOSPH7MPP7
Chromosome	21
Chromosome location	21q22.12-q22.13
Summary	Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is require

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SNP ID	Visualize variation	Clinical significance	Consequence
rs140630794	A>C,G	Likely-pathogenic	Intron variant, missense variant, coding sequence variant

326

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016399	hsa-miR-193b-3p	Microarray	20304954
MIRT020576	hsa-miR-155-5p	Proteomics	18668040
MIRT023664	hsa-miR-1-3p	Proteomics	18668040
MIRT042223	hsa-miR-484	CLASH	23622248
MIRT517897	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707475	hsa-miR-8485	HITS-CLIP	21572407
MIRT707474	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707473	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT707472	hsa-miR-603	HITS-CLIP	21572407
MIRT707471	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT509808	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509807	hsa-miR-154-3p	HITS-CLIP	21572407
MIRT509806	hsa-miR-487a-3p	HITS-CLIP	21572407
MIRT509805	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT517896	hsa-miR-1-5p	HITS-CLIP	21572407
MIRT517895	hsa-miR-581	HITS-CLIP	21572407
MIRT509804	hsa-miR-6748-5p	HITS-CLIP	21572407
MIRT509803	hsa-miR-6793-5p	HITS-CLIP	21572407
MIRT517894	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT509802	hsa-miR-3911	HITS-CLIP	21572407
MIRT509801	hsa-miR-644a	HITS-CLIP	21572407
MIRT509800	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT707470	hsa-miR-3941	HITS-CLIP	21572407
MIRT707469	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT509799	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT517893	hsa-miR-3924	HITS-CLIP	21572407
MIRT509798	hsa-miR-6741-5p	HITS-CLIP	21572407
MIRT509797	hsa-miR-6759-5p	HITS-CLIP	21572407
MIRT517892	hsa-miR-6818-5p	HITS-CLIP	21572407
MIRT509796	hsa-miR-147a	HITS-CLIP	21572407
MIRT509795	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23706177
MIRT669045	hsa-miR-1273g-3p	HITS-CLIP	23706177
MIRT636636	hsa-miR-6849-3p	HITS-CLIP	23706177
MIRT636634	hsa-miR-939-3p	HITS-CLIP	23706177
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23706177
MIRT669044	hsa-miR-4793-3p	HITS-CLIP	23706177
MIRT636625	hsa-miR-1285-3p	HITS-CLIP	23706177
MIRT636623	hsa-miR-3187-5p	HITS-CLIP	23706177
MIRT636624	hsa-miR-5189-5p	HITS-CLIP	23706177
MIRT636622	hsa-miR-612	HITS-CLIP	23706177
MIRT636621	hsa-miR-6860	HITS-CLIP	23706177
MIRT669043	hsa-miR-4252	HITS-CLIP	23706177
MIRT636618	hsa-miR-661	HITS-CLIP	23706177
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23706177
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23706177
MIRT669042	hsa-miR-7703	HITS-CLIP	23706177
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT669045	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT669044	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT669043	hsa-miR-4252	HITS-CLIP	23824327
MIRT636618	hsa-miR-661	HITS-CLIP	23824327
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT669042	hsa-miR-7703	HITS-CLIP	23824327
MIRT636642	hsa-miR-3667-5p	HITS-CLIP	23824327
MIRT636641	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT636640	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT636638	hsa-miR-451b	HITS-CLIP	23824327
MIRT636637	hsa-miR-6501-3p	HITS-CLIP	23824327
MIRT636636	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT636635	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT636634	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT636633	hsa-miR-4421	HITS-CLIP	23824327
MIRT636632	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT636631	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT636630	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT636629	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT636628	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT636627	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT636625	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT636623	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT636624	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT636622	hsa-miR-612	HITS-CLIP	23824327
MIRT636621	hsa-miR-6860	HITS-CLIP	23824327
MIRT636620	hsa-miR-4725-5p	HITS-CLIP	23824327
MIRT636619	hsa-miR-4696	HITS-CLIP	23824327
MIRT636618	hsa-miR-661	HITS-CLIP	23824327
MIRT636617	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT509794	hsa-miR-6890-5p	PAR-CLIP	20371350
MIRT509793	hsa-miR-4781-3p	PAR-CLIP	20371350
MIRT509792	hsa-miR-4716-5p	PAR-CLIP	20371350
MIRT509791	hsa-miR-1273f	PAR-CLIP	20371350
MIRT509790	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT509788	hsa-miR-23a-5p	PAR-CLIP	20371350
MIRT509789	hsa-miR-23b-5p	PAR-CLIP	20371350
MIRT563928	hsa-miR-6832-5p	PAR-CLIP	20371350
MIRT509787	hsa-miR-548s	PAR-CLIP	20371350
MIRT509786	hsa-miR-4701-5p	PAR-CLIP	20371350
MIRT509785	hsa-miR-588	PAR-CLIP	20371350
MIRT509784	hsa-miR-4435	PAR-CLIP	20371350
MIRT509783	hsa-miR-3187-3p	PAR-CLIP	20371350
MIRT509782	hsa-miR-3170	PAR-CLIP	20371350
MIRT509781	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT509779	hsa-miR-5096	PAR-CLIP	20371350
MIRT517897	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509807	hsa-miR-154-3p	PAR-CLIP	21572407
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	21572407
MIRT509805	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT517896	hsa-miR-1-5p	PAR-CLIP	21572407
MIRT517895	hsa-miR-581	PAR-CLIP	21572407
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	21572407
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	21572407
MIRT517894	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT509802	hsa-miR-3911	PAR-CLIP	21572407
MIRT509801	hsa-miR-644a	PAR-CLIP	21572407
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT517893	hsa-miR-3924	PAR-CLIP	21572407
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	21572407
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	21572407
MIRT517892	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT509796	hsa-miR-147a	PAR-CLIP	21572407
MIRT509795	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT517897	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509807	hsa-miR-154-3p	PAR-CLIP	23446348
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	23446348
MIRT509805	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT517896	hsa-miR-1-5p	PAR-CLIP	23446348
MIRT517895	hsa-miR-581	PAR-CLIP	23446348
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	23446348
MIRT517894	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT509802	hsa-miR-3911	PAR-CLIP	23446348
MIRT509801	hsa-miR-644a	PAR-CLIP	23446348
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT517893	hsa-miR-3924	PAR-CLIP	23446348
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	23446348
MIRT517892	hsa-miR-6818-5p	PAR-CLIP	23446348
MIRT509796	hsa-miR-147a	PAR-CLIP	23446348
MIRT509795	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT509808	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509807	hsa-miR-154-3p	PAR-CLIP	23446348
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	23446348
MIRT509805	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	23446348
MIRT509802	hsa-miR-3911	PAR-CLIP	23446348
MIRT509801	hsa-miR-644a	PAR-CLIP	23446348
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT509799	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	23446348
MIRT509796	hsa-miR-147a	PAR-CLIP	23446348
MIRT509795	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT509794	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT509793	hsa-miR-4781-3p	PAR-CLIP	23446348
MIRT509792	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT509791	hsa-miR-1273f	PAR-CLIP	23446348
MIRT509790	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT509788	hsa-miR-23a-5p	PAR-CLIP	23446348
MIRT509789	hsa-miR-23b-5p	PAR-CLIP	23446348
MIRT509787	hsa-miR-548s	PAR-CLIP	23446348
MIRT509786	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT509785	hsa-miR-588	PAR-CLIP	23446348
MIRT509784	hsa-miR-4435	PAR-CLIP	23446348
MIRT509783	hsa-miR-3187-3p	PAR-CLIP	23446348
MIRT509782	hsa-miR-3170	PAR-CLIP	23446348
MIRT509781	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT509779	hsa-miR-5096	PAR-CLIP	23446348
MIRT517897	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707475	hsa-miR-8485	HITS-CLIP	21572407
MIRT707474	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707473	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT707472	hsa-miR-603	HITS-CLIP	21572407
MIRT707471	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT509808	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT509807	hsa-miR-154-3p	HITS-CLIP	21572407
MIRT509806	hsa-miR-487a-3p	HITS-CLIP	21572407
MIRT509805	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT517896	hsa-miR-1-5p	HITS-CLIP	21572407
MIRT517895	hsa-miR-581	HITS-CLIP	21572407
MIRT509804	hsa-miR-6748-5p	HITS-CLIP	21572407
MIRT509803	hsa-miR-6793-5p	HITS-CLIP	21572407
MIRT517894	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT509802	hsa-miR-3911	HITS-CLIP	21572407
MIRT509801	hsa-miR-644a	HITS-CLIP	21572407
MIRT509800	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT707470	hsa-miR-3941	HITS-CLIP	21572407
MIRT707469	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT509799	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT517893	hsa-miR-3924	HITS-CLIP	21572407
MIRT509798	hsa-miR-6741-5p	HITS-CLIP	21572407
MIRT509797	hsa-miR-6759-5p	HITS-CLIP	21572407
MIRT517892	hsa-miR-6818-5p	HITS-CLIP	21572407
MIRT509796	hsa-miR-147a	HITS-CLIP	21572407
MIRT509795	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23706177
MIRT669045	hsa-miR-1273g-3p	HITS-CLIP	23706177
MIRT636636	hsa-miR-6849-3p	HITS-CLIP	23706177
MIRT636634	hsa-miR-939-3p	HITS-CLIP	23706177
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23706177
MIRT669044	hsa-miR-4793-3p	HITS-CLIP	23706177
MIRT636625	hsa-miR-1285-3p	HITS-CLIP	23706177
MIRT636623	hsa-miR-3187-5p	HITS-CLIP	23706177
MIRT636624	hsa-miR-5189-5p	HITS-CLIP	23706177
MIRT636622	hsa-miR-612	HITS-CLIP	23706177
MIRT636621	hsa-miR-6860	HITS-CLIP	23706177
MIRT669043	hsa-miR-4252	HITS-CLIP	23706177
MIRT636618	hsa-miR-661	HITS-CLIP	23706177
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23706177
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23706177
MIRT669042	hsa-miR-7703	HITS-CLIP	23706177
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT669045	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT669044	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT669043	hsa-miR-4252	HITS-CLIP	23824327
MIRT636618	hsa-miR-661	HITS-CLIP	23824327
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT669042	hsa-miR-7703	HITS-CLIP	23824327
MIRT636642	hsa-miR-3667-5p	HITS-CLIP	23824327
MIRT636641	hsa-miR-10a-5p	HITS-CLIP	23824327
MIRT636640	hsa-miR-10b-5p	HITS-CLIP	23824327
MIRT636639	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT636638	hsa-miR-451b	HITS-CLIP	23824327
MIRT636637	hsa-miR-6501-3p	HITS-CLIP	23824327
MIRT636636	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT636635	hsa-miR-339-5p	HITS-CLIP	23824327
MIRT636634	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT636633	hsa-miR-4421	HITS-CLIP	23824327
MIRT636632	hsa-miR-5699-3p	HITS-CLIP	23824327
MIRT636631	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT636630	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT636629	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT636628	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT636627	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT636626	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT636625	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT636623	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT636624	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT636622	hsa-miR-612	HITS-CLIP	23824327
MIRT636621	hsa-miR-6860	HITS-CLIP	23824327
MIRT636620	hsa-miR-4725-5p	HITS-CLIP	23824327
MIRT636619	hsa-miR-4696	HITS-CLIP	23824327
MIRT636618	hsa-miR-661	HITS-CLIP	23824327
MIRT636617	hsa-miR-196a-3p	HITS-CLIP	23824327
MIRT636616	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT636615	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT509794	hsa-miR-6890-5p	PAR-CLIP	20371350
MIRT509793	hsa-miR-4781-3p	PAR-CLIP	20371350
MIRT509792	hsa-miR-4716-5p	PAR-CLIP	20371350
MIRT509791	hsa-miR-1273f	PAR-CLIP	20371350
MIRT509790	hsa-miR-193b-5p	PAR-CLIP	20371350
MIRT509788	hsa-miR-23a-5p	PAR-CLIP	20371350
MIRT509789	hsa-miR-23b-5p	PAR-CLIP	20371350
MIRT563928	hsa-miR-6832-5p	PAR-CLIP	20371350
MIRT509787	hsa-miR-548s	PAR-CLIP	20371350
MIRT509786	hsa-miR-4701-5p	PAR-CLIP	20371350
MIRT509785	hsa-miR-588	PAR-CLIP	20371350
MIRT509784	hsa-miR-4435	PAR-CLIP	20371350
MIRT509783	hsa-miR-3187-3p	PAR-CLIP	20371350
MIRT509782	hsa-miR-3170	PAR-CLIP	20371350
MIRT509781	hsa-miR-6855-5p	PAR-CLIP	20371350
MIRT509779	hsa-miR-5096	PAR-CLIP	20371350
MIRT517897	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT509807	hsa-miR-154-3p	PAR-CLIP	21572407
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	21572407
MIRT509805	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT517896	hsa-miR-1-5p	PAR-CLIP	21572407
MIRT517895	hsa-miR-581	PAR-CLIP	21572407
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	21572407
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	21572407
MIRT517894	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT509802	hsa-miR-3911	PAR-CLIP	21572407
MIRT509801	hsa-miR-644a	PAR-CLIP	21572407
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT517893	hsa-miR-3924	PAR-CLIP	21572407
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	21572407
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	21572407
MIRT517892	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT509796	hsa-miR-147a	PAR-CLIP	21572407
MIRT509795	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT517897	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT509807	hsa-miR-154-3p	PAR-CLIP	23446348
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	23446348
MIRT509805	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT517896	hsa-miR-1-5p	PAR-CLIP	23446348
MIRT517895	hsa-miR-581	PAR-CLIP	23446348
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	23446348
MIRT517894	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT509802	hsa-miR-3911	PAR-CLIP	23446348
MIRT509801	hsa-miR-644a	PAR-CLIP	23446348
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT517893	hsa-miR-3924	PAR-CLIP	23446348
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	23446348
MIRT517892	hsa-miR-6818-5p	PAR-CLIP	23446348
MIRT509796	hsa-miR-147a	PAR-CLIP	23446348
MIRT509795	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT509808	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT509807	hsa-miR-154-3p	PAR-CLIP	23446348
MIRT509806	hsa-miR-487a-3p	PAR-CLIP	23446348
MIRT509805	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT509804	hsa-miR-6748-5p	PAR-CLIP	23446348
MIRT509803	hsa-miR-6793-5p	PAR-CLIP	23446348
MIRT509802	hsa-miR-3911	PAR-CLIP	23446348
MIRT509801	hsa-miR-644a	PAR-CLIP	23446348
MIRT509800	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT509799	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT509798	hsa-miR-6741-5p	PAR-CLIP	23446348
MIRT509797	hsa-miR-6759-5p	PAR-CLIP	23446348
MIRT509796	hsa-miR-147a	PAR-CLIP	23446348
MIRT509795	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT509794	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT509793	hsa-miR-4781-3p	PAR-CLIP	23446348
MIRT509792	hsa-miR-4716-5p	PAR-CLIP	23446348
MIRT509791	hsa-miR-1273f	PAR-CLIP	23446348
MIRT509790	hsa-miR-193b-5p	PAR-CLIP	23446348
MIRT509788	hsa-miR-23a-5p	PAR-CLIP	23446348
MIRT509789	hsa-miR-23b-5p	PAR-CLIP	23446348
MIRT509787	hsa-miR-548s	PAR-CLIP	23446348
MIRT509786	hsa-miR-4701-5p	PAR-CLIP	23446348
MIRT509785	hsa-miR-588	PAR-CLIP	23446348
MIRT509784	hsa-miR-4435	PAR-CLIP	23446348
MIRT509783	hsa-miR-3187-3p	PAR-CLIP	23446348
MIRT509782	hsa-miR-3170	PAR-CLIP	23446348
MIRT509781	hsa-miR-6855-5p	PAR-CLIP	23446348
MIRT509779	hsa-miR-5096	PAR-CLIP	23446348

Show/Hide all (25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IDA	9614144, 14718166
GO:0003682	Function	Chromatin binding	TAS	7600578
GO:0005515	Function	Protein binding	IPI	16980972, 24981860, 27705803, 28514442, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	9614144
GO:0005654	Component	Nucleoplasm	HDA	16780588
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	NAS	9614144
GO:0005829	Component	Cytosol	HDA	16780588
GO:0006260	Process	DNA replication	IEA
GO:0006281	Process	DNA repair	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006334	Process	Nucleosome assembly	IBA
GO:0006334	Process	Nucleosome assembly	IDA	14718166
GO:0006335	Process	DNA replication-dependent chromatin assembly	IDA	8858152, 9614144
GO:0006335	Process	DNA replication-dependent chromatin assembly	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0032991	Component	Protein-containing complex	IDA	14718166
GO:0033186	Component	CAF-1 complex	IBA
GO:0033186	Component	CAF-1 complex	IDA	8858152
GO:0033186	Component	CAF-1 complex	IPI	9614144
GO:0042393	Function	Histone binding	NAS	7600578
GO:0051082	Function	Unfolded protein binding	TAS	7600578

MIM	HGNC	e!Ensembl
601245	1911	ENSG00000159259

Q13112

Protein name

Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (M-phase phosphoprotein 7)

Protein function

Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly s

PDB

7Y5K , 7Y5L , 7Y5O , 7Y5U , 7Y5V , 7Y60 , 7Y61 , 8IQF , 8IQG , 8J6S , 8J6T

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00400	WD40	57 → 94	WD domain, G-beta repeat	Repeat
PF00400	WD40	119 → 157	WD domain, G-beta repeat	Repeat
PF00400	WD40	161 → 199	WD domain, G-beta repeat	Repeat
PF15512	CAF-1_p60_C	381 → 555	Chromatin assembly factor complex 1 subunit p60, C-terminal	Domain

Sequence

MKVITCEIAWHNKEPVYSLDFQHGTAGRIHRLASAGVDTNVRIWKVEKGPDGKAIVEFLS
NLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWT
VVKTLRGHLEDVYDICWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWD
PLGQYVATLSCDRVLRVYSIQKKRVAFNVSKMLSGIGAEGEARSYRMFHDDSMKSFFRRL
SFTPDGSLLLTPAGCVESGENVMNTTYVFSRKNLKRPIAHLPCPGKATLAVRCCPVYFEL
RPVVETGVELMSLPYRLVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAF
LAISSTDGYCSFVTFEKDELGIPLKEKPVLNMRTPDTAKKTKSQTHRGSSPGPRPVEGTP
ASRTQDPSSPGTTPPQARQAPAPTVIRDPPSITPAVKSPLPGPSEEKTLQPSSQNTKAHP
SRRVTLNTLQAWSKTTPRRINLTPLKTDTPPSSVPTSVISTPSTEEIQSETPGDAQGSPP
ELKRPRLDENKGGTESLDP

Sequence length

559

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Causal Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession	Evidence Score
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Attention deficit hyperactivity disorder	Likely pathogenic	rs140630794	RCV000162182	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Global developmental delay	Likely pathogenic	rs140630794	RCV000162182	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Intellectual disability	Likely pathogenic	rs140630794	RCV000162182	★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CARCINOMA, HEPATOCELLULAR	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOUTH DISEASES	—	CTD, Disgenet CTD, Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TREATMENT-RESISTANT HYPERTENSION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (33)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Attention deficit hyperactivity disorder	Attention Deficit Hyperactivity Disorder	CLINVAR_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Breast Carcinoma	Breast Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Burkitt Lymphoma	Burkitt lymphoma	Pubtator	33109754	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma of larynx	Laryngeal carcinoma	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cutaneous Melanoma	Melanoma	BEFREE	23109837		★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	LHGDN	15068244		★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Down Syndrome	BEFREE	8660983, 8792829		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	24039914	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	CLINVAR_DG			★★★★★ ★★★★☆ ClinVar: Pathogenic / Likely Pathogenic (<5 Variants)
Laryngeal neoplasm	Laryngeal neoplasm	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Laryngeal Squamous Cell Carcinoma	Laryngeal Carcinoma	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	30423290, 30423293		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid	Myeloid leukemia	Pubtator	31640433	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	20053754, 32783661, 37216686	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Lip and Oral Cavity Carcinoma	Lip and Oral Cavity Carcinoma	BEFREE	25697104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	CTD_human_DG	28284560		★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	29767268		★★★★★ ★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	24836587, 28553742		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of larynx	Larynx cancer	BEFREE	28374866		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	29767268		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of mouth	Malignant neoplasm of mouth	BEFREE	25697104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21083601, 23109837, 25697104		★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Melanoma	Pubtator	39766913	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Mouth Diseases	Mouth Diseases	CTD_human_DG	17682004		★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Muscular Dystrophy, Facioscapulohumeral	Facioscapulohumeral Muscular Dystrophy	BEFREE	29533181		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	21083601, 23109837, 29767268, 30720130		★★★★★ ★☆☆☆☆ Found in Text Mining only
Non-Small Cell Lung Carcinoma	Lung carcinoma	BEFREE	30720130		★★★★★ ★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	21083601		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	BEFREE	17543081, 31627329		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of tongue	Tongue carcinoma	BEFREE	17543081		★★★★★ ★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Uterine neoplasm	Pubtator	33616161	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

CHAF1B (chromatin assembly factor 1 subunit B)