Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	8193
Gene name	Double PHD fingers 1
Gene symbol	DPF1
Synonyms (NCBI Gene)	BAF45bNEUD4SMARCG1neuro-d4
Chromosome	19
Chromosome location	19q13.2

Show/Hide all (83)

miRTarBase ID	miRNA	Experiments	Reference
MIRT047000	hsa-miR-212-3p	CLASH	23622248
MIRT046214	hsa-miR-27b-3p	CLASH	23622248
MIRT040773	hsa-miR-18a-3p	CLASH	23622248
MIRT486874	hsa-miR-4779	PAR-CLIP	23592263
MIRT486873	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT486872	hsa-miR-4419a	PAR-CLIP	23592263
MIRT486871	hsa-miR-4510	PAR-CLIP	23592263
MIRT486870	hsa-miR-6127	PAR-CLIP	23592263
MIRT486869	hsa-miR-6129	PAR-CLIP	23592263
MIRT486868	hsa-miR-6130	PAR-CLIP	23592263
MIRT486867	hsa-miR-6133	PAR-CLIP	23592263
MIRT486866	hsa-miR-744-5p	PAR-CLIP	23592263
MIRT486865	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT486864	hsa-miR-4306	PAR-CLIP	23592263
MIRT486862	hsa-miR-4644	PAR-CLIP	23592263
MIRT486863	hsa-miR-765	PAR-CLIP	23592263
MIRT486861	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT486860	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT486859	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT486858	hsa-miR-663a	PAR-CLIP	23592263
MIRT486857	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT486856	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT486855	hsa-miR-8085	PAR-CLIP	23592263
MIRT486854	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT486853	hsa-miR-3180	PAR-CLIP	23592263
MIRT486852	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT486851	hsa-miR-3196	PAR-CLIP	23592263
MIRT486849	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT486874	hsa-miR-4779	PAR-CLIP	23592263
MIRT486873	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT486872	hsa-miR-4419a	PAR-CLIP	23592263
MIRT486871	hsa-miR-4510	PAR-CLIP	23592263
MIRT486870	hsa-miR-6127	PAR-CLIP	23592263
MIRT486869	hsa-miR-6129	PAR-CLIP	23592263
MIRT486868	hsa-miR-6130	PAR-CLIP	23592263
MIRT486867	hsa-miR-6133	PAR-CLIP	23592263
MIRT486866	hsa-miR-744-5p	PAR-CLIP	23592263
MIRT486865	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT486864	hsa-miR-4306	PAR-CLIP	23592263
MIRT486862	hsa-miR-4644	PAR-CLIP	23592263
MIRT486863	hsa-miR-765	PAR-CLIP	23592263
MIRT486861	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT486860	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT486859	hsa-miR-1908-5p	PAR-CLIP	23592263
MIRT486858	hsa-miR-663a	PAR-CLIP	23592263
MIRT486857	hsa-miR-6787-5p	PAR-CLIP	23592263
MIRT486856	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT486855	hsa-miR-8085	PAR-CLIP	23592263
MIRT486854	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT486853	hsa-miR-3180	PAR-CLIP	23592263
MIRT486852	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT486851	hsa-miR-3196	PAR-CLIP	23592263
MIRT486849	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT943724	hsa-miR-1184	CLIP-seq
MIRT943725	hsa-miR-1224-3p	CLIP-seq
MIRT943726	hsa-miR-1262	CLIP-seq
MIRT943727	hsa-miR-1293	CLIP-seq
MIRT943728	hsa-miR-1301	CLIP-seq
MIRT943729	hsa-miR-2277-5p	CLIP-seq
MIRT943730	hsa-miR-3151	CLIP-seq
MIRT943731	hsa-miR-3166	CLIP-seq
MIRT943732	hsa-miR-3170	CLIP-seq
MIRT943733	hsa-miR-3178	CLIP-seq
MIRT943734	hsa-miR-3189-3p	CLIP-seq
MIRT943735	hsa-miR-4260	CLIP-seq
MIRT943736	hsa-miR-4436b-3p	CLIP-seq
MIRT943737	hsa-miR-4436b-5p	CLIP-seq
MIRT943738	hsa-miR-4483	CLIP-seq
MIRT943739	hsa-miR-4660	CLIP-seq
MIRT943740	hsa-miR-4701-3p	CLIP-seq
MIRT943741	hsa-miR-4747-5p	CLIP-seq
MIRT943742	hsa-miR-5047	CLIP-seq
MIRT943743	hsa-miR-524-3p	CLIP-seq
MIRT943744	hsa-miR-525-3p	CLIP-seq
MIRT943725	hsa-miR-1224-3p	CLIP-seq
MIRT943745	hsa-miR-361-3p	CLIP-seq
MIRT943746	hsa-miR-1972	CLIP-seq
MIRT943747	hsa-miR-2467-3p	CLIP-seq
MIRT943748	hsa-miR-4650-5p	CLIP-seq
MIRT1979463	hsa-miR-1908	CLIP-seq
MIRT1979464	hsa-miR-4638-5p	CLIP-seq
MIRT1979465	hsa-miR-663	CLIP-seq
MIRT943747	hsa-miR-2467-3p	CLIP-seq

Show/Hide all (23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	NAS	12192000
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IEA
GO:0006338	Process	Chromatin remodeling	NAS	10078207
GO:0006357	Process	Regulation of transcription by RNA polymerase II	NAS	17920018
GO:0006915	Process	Apoptotic process	TAS	8812431
GO:0007399	Process	Nervous system development	IBA
GO:0007399	Process	Nervous system development	IEA
GO:0007399	Process	Nervous system development	ISS
GO:0008270	Function	Zinc ion binding	IEA
GO:0030071	Process	Regulation of mitotic metaphase/anaphase transition	NAS	23698369
GO:0045597	Process	Positive regulation of cell differentiation	NAS	11790558
GO:0046872	Function	Metal ion binding	IEA
GO:0070316	Process	Regulation of G0 to G1 transition	NAS	11790558
GO:0071565	Component	NBAF complex	IBA
GO:0071565	Component	NBAF complex	ISS
GO:0071565	Component	NBAF complex	NAS	17920018
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:2000045	Process	Regulation of G1/S transition of mitotic cell cycle	NAS	10778858
GO:2000781	Process	Positive regulation of double-strand break repair	NAS	16932743
GO:2000819	Process	Regulation of nucleotide-excision repair	NAS	12215535

MIM	HGNC	e!Ensembl
601670	20225	ENSG00000011332

Q92782

Protein name

Zinc finger protein neuro-d4 (BRG1-associated factor 45B) (BAF45B) (D4, zinc and double PHD fingers family 1)

Protein function

May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14051	Requiem_N	39 → 110	N-terminal domain of DPF2/REQ.	Family
PF00628	PHD	256 → 311	PHD-finger	Domain
PF00628	PHD	310 → 368	PHD-finger	Domain

Sequence

MGGLSARPTAGRTDPAGTCWGQDPGSKMATVIPGPLSLGEDFYREAIEHCRSYNARLCAE
RSLRLPFLDSQTGVAQNNCYIWMEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLR
PCEYKIDCEAPLKKEGGLPEGPVLEALLCAETGEKKIELKEEETIMDCQKQQLLEFPHDL
EVEDLEDDIPRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDKFYKELAWVPEAQRK
HTAKKAPDGTVIPNGYCDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRT
YRWQCIECKSCSLCGTSENDGASWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSW
SCHLCLRHLKEKASAYITLT

Sequence length

380

Interactions

View interactions

	KEGG
	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (6)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Glioblastoma	Glioblastoma	BEFREE	28420882		★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	Pubtator	28420882	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28420882		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hereditary Breast and Ovarian Cancer Syndrome	Hereditary breast and ovarian cancer syndrome	Pubtator	28115406	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Diseases	Ovarian diseases	Pubtator	28115406	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	28115406	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

DPF1 (double PHD fingers 1)