Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	81602
Gene name	Cytidine and dCMP deaminase domain containing 1
Gene symbol	CDADC1
Synonyms (NCBI Gene)	NYD-SP15bA103J18.1
Chromosome	13
Chromosome location	13q14.2

192

Show/Hide all (192)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023013	hsa-miR-124-3p	Microarray	18668037
MIRT027165	hsa-miR-103a-3p	Sequencing	20371350
MIRT031993	hsa-miR-16-5p	Sequencing	20371350
MIRT189760	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT189762	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT031993	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT189763	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT189764	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT189765	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT189779	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT572188	hsa-miR-3675-5p	PAR-CLIP	20371350
MIRT572187	hsa-miR-6890-5p	PAR-CLIP	20371350
MIRT189769	hsa-miR-4310	PAR-CLIP	20371350
MIRT189782	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT189775	hsa-miR-4729	PAR-CLIP	20371350
MIRT027165	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT189761	hsa-miR-107	PAR-CLIP	20371350
MIRT189777	hsa-miR-6081	PAR-CLIP	20371350
MIRT189773	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT189766	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT572186	hsa-miR-625-5p	PAR-CLIP	20371350
MIRT189774	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT189776	hsa-miR-5698	PAR-CLIP	20371350
MIRT189780	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT189781	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT572184	hsa-miR-4525	PAR-CLIP	20371350
MIRT572185	hsa-miR-5010-5p	PAR-CLIP	20371350
MIRT189771	hsa-miR-4477a	PAR-CLIP	20371350
MIRT189768	hsa-miR-1275	PAR-CLIP	20371350
MIRT189772	hsa-miR-4665-5p	PAR-CLIP	20371350
MIRT368763	hsa-miR-4295	PAR-CLIP	22100165
MIRT368752	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT368754	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT368759	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT368764	hsa-miR-3666	PAR-CLIP	22100165
MIRT368760	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT368753	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT368757	hsa-miR-519a-3p	PAR-CLIP	22100165
MIRT368756	hsa-miR-519b-3p	PAR-CLIP	22100165
MIRT368755	hsa-miR-519c-3p	PAR-CLIP	22100165
MIRT448966	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT448964	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT448965	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT448963	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT448962	hsa-miR-6086	PAR-CLIP	22100165
MIRT368750	hsa-miR-106a-3p	PAR-CLIP	22100165
MIRT368763	hsa-miR-4295	PAR-CLIP	22100165
MIRT368752	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT368754	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT368759	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT368764	hsa-miR-3666	PAR-CLIP	22100165
MIRT368760	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT368753	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT368757	hsa-miR-519a-3p	PAR-CLIP	22100165
MIRT368756	hsa-miR-519b-3p	PAR-CLIP	22100165
MIRT368755	hsa-miR-519c-3p	PAR-CLIP	22100165
MIRT448966	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT448964	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT448965	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT448963	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT448962	hsa-miR-6086	PAR-CLIP	22100165
MIRT368750	hsa-miR-106a-3p	PAR-CLIP	22100165
MIRT189760	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT189762	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT031993	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT189763	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT189764	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT189765	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT189779	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT572188	hsa-miR-3675-5p	PAR-CLIP	20371350
MIRT572187	hsa-miR-6890-5p	PAR-CLIP	20371350
MIRT189769	hsa-miR-4310	PAR-CLIP	20371350
MIRT189782	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT189775	hsa-miR-4729	PAR-CLIP	20371350
MIRT027165	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT189761	hsa-miR-107	PAR-CLIP	20371350
MIRT189777	hsa-miR-6081	PAR-CLIP	20371350
MIRT189773	hsa-miR-1343-5p	PAR-CLIP	20371350
MIRT189766	hsa-miR-939-5p	PAR-CLIP	20371350
MIRT572186	hsa-miR-625-5p	PAR-CLIP	20371350
MIRT189774	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT189776	hsa-miR-5698	PAR-CLIP	20371350
MIRT189780	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT189781	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT572184	hsa-miR-4525	PAR-CLIP	20371350
MIRT572185	hsa-miR-5010-5p	PAR-CLIP	20371350
MIRT189771	hsa-miR-4477a	PAR-CLIP	20371350
MIRT189768	hsa-miR-1275	PAR-CLIP	20371350
MIRT189772	hsa-miR-4665-5p	PAR-CLIP	20371350
MIRT368763	hsa-miR-4295	PAR-CLIP	22100165
MIRT368752	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT368754	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT368759	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT368764	hsa-miR-3666	PAR-CLIP	22100165
MIRT368760	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT368753	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT368757	hsa-miR-519a-3p	PAR-CLIP	22100165
MIRT368756	hsa-miR-519b-3p	PAR-CLIP	22100165
MIRT368755	hsa-miR-519c-3p	PAR-CLIP	22100165
MIRT448966	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT448964	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT448965	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT448963	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT448962	hsa-miR-6086	PAR-CLIP	22100165
MIRT368750	hsa-miR-106a-3p	PAR-CLIP	22100165
MIRT368763	hsa-miR-4295	PAR-CLIP	22100165
MIRT368752	hsa-miR-130a-3p	PAR-CLIP	22100165
MIRT368754	hsa-miR-130b-3p	PAR-CLIP	22100165
MIRT368759	hsa-miR-454-3p	PAR-CLIP	22100165
MIRT368764	hsa-miR-3666	PAR-CLIP	22100165
MIRT368760	hsa-miR-301b-3p	PAR-CLIP	22100165
MIRT368753	hsa-miR-301a-3p	PAR-CLIP	22100165
MIRT368757	hsa-miR-519a-3p	PAR-CLIP	22100165
MIRT368756	hsa-miR-519b-3p	PAR-CLIP	22100165
MIRT368755	hsa-miR-519c-3p	PAR-CLIP	22100165
MIRT448966	hsa-miR-148a-5p	PAR-CLIP	22100165
MIRT448964	hsa-miR-5584-3p	PAR-CLIP	22100165
MIRT448965	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT448963	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT448962	hsa-miR-6086	PAR-CLIP	22100165
MIRT368750	hsa-miR-106a-3p	PAR-CLIP	22100165
MIRT876672	hsa-miR-128	CLIP-seq
MIRT876673	hsa-miR-1976	CLIP-seq
MIRT876674	hsa-miR-204	CLIP-seq
MIRT876675	hsa-miR-211	CLIP-seq
MIRT876676	hsa-miR-27a	CLIP-seq
MIRT876677	hsa-miR-27b	CLIP-seq
MIRT876678	hsa-miR-3177-5p	CLIP-seq
MIRT876679	hsa-miR-3183	CLIP-seq
MIRT876680	hsa-miR-34b	CLIP-seq
MIRT876681	hsa-miR-4251	CLIP-seq
MIRT876682	hsa-miR-4263	CLIP-seq
MIRT876683	hsa-miR-4303	CLIP-seq
MIRT876684	hsa-miR-4329	CLIP-seq
MIRT876685	hsa-miR-4438	CLIP-seq
MIRT876686	hsa-miR-4446-5p	CLIP-seq
MIRT876687	hsa-miR-4672	CLIP-seq
MIRT876688	hsa-miR-4680-5p	CLIP-seq
MIRT876689	hsa-miR-4723-3p	CLIP-seq
MIRT876690	hsa-miR-4738-3p	CLIP-seq
MIRT876691	hsa-miR-4755-5p	CLIP-seq
MIRT876692	hsa-miR-499-3p	CLIP-seq
MIRT876693	hsa-miR-499a-3p	CLIP-seq
MIRT876694	hsa-miR-539	CLIP-seq
MIRT876695	hsa-miR-576-5p	CLIP-seq
MIRT876696	hsa-miR-582-3p	CLIP-seq
MIRT876697	hsa-miR-595	CLIP-seq
MIRT876698	hsa-miR-623	CLIP-seq
MIRT2196832	hsa-miR-1208	CLIP-seq
MIRT2196833	hsa-miR-1304	CLIP-seq
MIRT2196834	hsa-miR-2467-3p	CLIP-seq
MIRT2196835	hsa-miR-3606	CLIP-seq
MIRT2196836	hsa-miR-4420	CLIP-seq
MIRT2196837	hsa-miR-4470	CLIP-seq
MIRT2196838	hsa-miR-921	CLIP-seq
MIRT2500088	hsa-miR-186	CLIP-seq
MIRT2500089	hsa-miR-2053	CLIP-seq
MIRT2500090	hsa-miR-2054	CLIP-seq
MIRT2196834	hsa-miR-2467-3p	CLIP-seq
MIRT2500091	hsa-miR-3154	CLIP-seq
MIRT2500092	hsa-miR-3158-5p	CLIP-seq
MIRT2500093	hsa-miR-3650	CLIP-seq
MIRT2500094	hsa-miR-3678-3p	CLIP-seq
MIRT2500095	hsa-miR-371-5p	CLIP-seq
MIRT2500096	hsa-miR-371b-5p	CLIP-seq
MIRT2500097	hsa-miR-3938	CLIP-seq
MIRT2500098	hsa-miR-4639-3p	CLIP-seq
MIRT2500099	hsa-miR-4714-3p	CLIP-seq
MIRT2500100	hsa-miR-4760-3p	CLIP-seq
MIRT2500101	hsa-miR-4789-5p	CLIP-seq
MIRT2500102	hsa-miR-513c	CLIP-seq
MIRT2500103	hsa-miR-514b-5p	CLIP-seq
MIRT2500104	hsa-miR-569	CLIP-seq
MIRT2500105	hsa-miR-643	CLIP-seq
MIRT2500106	hsa-miR-668	CLIP-seq
MIRT2500107	hsa-miR-670	CLIP-seq
MIRT2500108	hsa-miR-7	CLIP-seq
MIRT2500109	hsa-miR-889	CLIP-seq
MIRT2500110	hsa-miR-944	CLIP-seq
MIRT2500088	hsa-miR-186	CLIP-seq
MIRT2500089	hsa-miR-2053	CLIP-seq
MIRT2500090	hsa-miR-2054	CLIP-seq
MIRT2500091	hsa-miR-3154	CLIP-seq
MIRT2500098	hsa-miR-4639-3p	CLIP-seq
MIRT2500099	hsa-miR-4714-3p	CLIP-seq
MIRT2500100	hsa-miR-4760-3p	CLIP-seq
MIRT2500101	hsa-miR-4789-5p	CLIP-seq
MIRT2500104	hsa-miR-569	CLIP-seq
MIRT2500105	hsa-miR-643	CLIP-seq
MIRT2500106	hsa-miR-668	CLIP-seq
MIRT2500108	hsa-miR-7	CLIP-seq
MIRT2500110	hsa-miR-944	CLIP-seq

Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003824	Function	Catalytic activity	IEA
GO:0004126	Function	Cytidine deaminase activity	IDA	26945630
GO:0004126	Function	Cytidine deaminase activity	IEA
GO:0004132	Function	DCMP deaminase activity	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	IMP	26945630
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	IMP	26945630
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	IMP	26945630
GO:0016787	Function	Hydrolase activity	IEA
GO:0042803	Function	Protein homodimerization activity	IDA	26945630
GO:0046872	Function	Metal ion binding	IEA
GO:0061676	Function	Importin-alpha family protein binding	IDA	26945630
GO:0070383	Process	DNA cytosine deamination	IDA	26945630

MIM	HGNC	e!Ensembl
618997	20299	ENSG00000102543

Q9BWV3

Protein name

Cytidine and dCMP deaminase domain-containing protein 1 (EC 3.5.4.5) (Cytidine deaminase) (Testis development protein NYD-SP15)

Protein function

Catalyzes the deamination of cytidine and deoxycytidine into uridine and deoxyuridine, respectively (PubMed:26945630). May play an important role in testicular development and spermatogenesis (PubMed:16955368). {ECO:0000269|PubMed:16955368, ECO:

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00383	dCMP_cyt_deam_1	73 → 152	Cytidine and deoxycytidylate deaminase zinc-binding region	Family
PF00383	dCMP_cyt_deam_1	316 → 445	Cytidine and deoxycytidylate deaminase zinc-binding region	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. Expressed at high levels in the testis. {ECO:0000269|PubMed:16955368}.

Sequence

MKEAGQMQNLESARAGRSVSTQTGSMTGQIPRLSKVNLFTLLSLWMELFPAEAQRQKSQK
NEEGKHGPLGDNEERTRVSTDKRQVKRTGLVVVKNMKIVGLHCSSEDLHAGQIALIKHGS
RLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPADPEISLLTEASSSEDAKLDAKAVERL
KSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKITKTLPDANTDFYYECKQERIKEYE
MLFLVSNEEMHKQILMTIGLENLCENPYFSNLRQNMKDLILLLATVASSVPNFKHFGFYR
SNPEQINEIHNQSLPQEIARHCMVQARLLAYRTEDHKTGVGAVIWAEGKSRSCDGTGAMY
FVGCGYNAFPVGSEYADFPHMDDKQKDREIRKFRYIIHAEQNALTFRCQEIKPEERSMIF
VTKCPCDECVPLIKGAGIKQIYAGDVDVGKKKADISYMRFGELEGVSKFTWQLNPSGAYG
LEQNEPERRENGVLRPVPQKEEQHQDKKLRLGIH

Sequence length

514

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Hepatocellular carcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

CDADC1 (cytidine and dCMP deaminase domain containing 1)