Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	81035
Gene name	Collectin subfamily member 12
Gene symbol	COLEC12
Synonyms (NCBI Gene)	CLP1NSR2SCARA4SRCL
Chromosome	18
Chromosome location	18p11.32
Summary	This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carboh

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021483	hsa-miR-9-5p	Sequencing	20371350
MIRT025879	hsa-miR-7-5p	Sequencing	20371350
MIRT029943	hsa-miR-26b-5p	Microarray	19088304
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT640137	hsa-miR-29b-2-5p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT640136	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT640135	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT640134	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT548788	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT548787	hsa-miR-4500	PAR-CLIP	21572407
MIRT548786	hsa-miR-4458	PAR-CLIP	21572407
MIRT548784	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT548785	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT548783	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT548782	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT548781	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT548779	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT548780	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT548778	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT548777	hsa-miR-4517	PAR-CLIP	21572407
MIRT548775	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT548776	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT548774	hsa-miR-4999-3p	PAR-CLIP	21572407
MIRT548773	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT548771	hsa-miR-877-5p	PAR-CLIP	21572407
MIRT548772	hsa-miR-6866-5p	PAR-CLIP	21572407
MIRT548770	hsa-miR-1303	PAR-CLIP	21572407
MIRT548788	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT548787	hsa-miR-4500	PAR-CLIP	21572407
MIRT548786	hsa-miR-4458	PAR-CLIP	21572407
MIRT548784	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT548785	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT548783	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT548782	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT548781	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT548779	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT548780	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT548778	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT548777	hsa-miR-4517	PAR-CLIP	21572407
MIRT548775	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT548776	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT548774	hsa-miR-4999-3p	PAR-CLIP	21572407
MIRT548773	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT548771	hsa-miR-877-5p	PAR-CLIP	21572407
MIRT548772	hsa-miR-6866-5p	PAR-CLIP	21572407
MIRT548770	hsa-miR-1303	PAR-CLIP	21572407
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT640137	hsa-miR-29b-2-5p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT640136	hsa-miR-30a-3p	HITS-CLIP	23824327
MIRT640135	hsa-miR-30d-3p	HITS-CLIP	23824327
MIRT640134	hsa-miR-30e-3p	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615075	hsa-miR-520f-3p	HITS-CLIP	23824327
MIRT615074	hsa-miR-302c-3p	HITS-CLIP	23824327
MIRT615073	hsa-miR-148a-3p	HITS-CLIP	23824327
MIRT615072	hsa-miR-148b-3p	HITS-CLIP	23824327
MIRT615071	hsa-miR-152-3p	HITS-CLIP	23824327
MIRT615070	hsa-miR-4502	HITS-CLIP	23824327
MIRT615069	hsa-miR-1253	HITS-CLIP	23824327
MIRT615068	hsa-miR-6770-5p	HITS-CLIP	23824327
MIRT615067	hsa-miR-3140-3p	HITS-CLIP	23824327
MIRT615066	hsa-miR-4276	HITS-CLIP	23824327
MIRT615065	hsa-miR-1305	HITS-CLIP	23824327
MIRT615064	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT548788	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT548787	hsa-miR-4500	PAR-CLIP	21572407
MIRT548786	hsa-miR-4458	PAR-CLIP	21572407
MIRT548784	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT548785	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT548783	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT548782	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT548781	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT548779	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT548780	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT548778	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT548777	hsa-miR-4517	PAR-CLIP	21572407
MIRT548775	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT548776	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT548774	hsa-miR-4999-3p	PAR-CLIP	21572407
MIRT548773	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT548771	hsa-miR-877-5p	PAR-CLIP	21572407
MIRT548772	hsa-miR-6866-5p	PAR-CLIP	21572407
MIRT548770	hsa-miR-1303	PAR-CLIP	21572407
MIRT548788	hsa-miR-98-5p	PAR-CLIP	21572407
MIRT548787	hsa-miR-4500	PAR-CLIP	21572407
MIRT548786	hsa-miR-4458	PAR-CLIP	21572407
MIRT548784	hsa-let-7i-5p	PAR-CLIP	21572407
MIRT548785	hsa-let-7a-5p	PAR-CLIP	21572407
MIRT548783	hsa-let-7b-5p	PAR-CLIP	21572407
MIRT548782	hsa-let-7c-5p	PAR-CLIP	21572407
MIRT548781	hsa-let-7f-5p	PAR-CLIP	21572407
MIRT548779	hsa-let-7e-5p	PAR-CLIP	21572407
MIRT548780	hsa-let-7d-5p	PAR-CLIP	21572407
MIRT548778	hsa-let-7g-5p	PAR-CLIP	21572407
MIRT548777	hsa-miR-4517	PAR-CLIP	21572407
MIRT548775	hsa-miR-3927-3p	PAR-CLIP	21572407
MIRT548776	hsa-miR-6831-5p	PAR-CLIP	21572407
MIRT548774	hsa-miR-4999-3p	PAR-CLIP	21572407
MIRT548773	hsa-miR-4650-3p	PAR-CLIP	21572407
MIRT548771	hsa-miR-877-5p	PAR-CLIP	21572407
MIRT548772	hsa-miR-6866-5p	PAR-CLIP	21572407
MIRT548770	hsa-miR-1303	PAR-CLIP	21572407
MIRT903259	hsa-miR-3617	CLIP-seq
MIRT903260	hsa-miR-520d-5p	CLIP-seq
MIRT903261	hsa-miR-524-5p	CLIP-seq
MIRT903262	hsa-miR-561	CLIP-seq
MIRT903263	hsa-miR-587	CLIP-seq
MIRT903264	hsa-miR-641	CLIP-seq
MIRT903265	hsa-miR-7	CLIP-seq
MIRT1547395	hsa-miR-3064-3p	CLIP-seq
MIRT1547396	hsa-miR-4252	CLIP-seq
MIRT1547397	hsa-miR-4715-3p	CLIP-seq
MIRT1547398	hsa-miR-4776-3p	CLIP-seq
MIRT2203666	hsa-miR-1225-5p	CLIP-seq
MIRT2203667	hsa-miR-1264	CLIP-seq
MIRT2203668	hsa-miR-297	CLIP-seq
MIRT2203669	hsa-miR-346	CLIP-seq
MIRT2203670	hsa-miR-3614-5p	CLIP-seq
MIRT2203671	hsa-miR-3685	CLIP-seq
MIRT2203672	hsa-miR-3691-3p	CLIP-seq
MIRT2203673	hsa-miR-384	CLIP-seq
MIRT2203674	hsa-miR-3920	CLIP-seq
MIRT2203675	hsa-miR-4288	CLIP-seq
MIRT2203676	hsa-miR-448	CLIP-seq
MIRT2203677	hsa-miR-4716-5p	CLIP-seq
MIRT2203678	hsa-miR-4720-3p	CLIP-seq
MIRT2203679	hsa-miR-4742-3p	CLIP-seq
MIRT2203680	hsa-miR-4762-3p	CLIP-seq
MIRT2203681	hsa-miR-4804-3p	CLIP-seq
MIRT2203682	hsa-miR-509-3p	CLIP-seq
MIRT2203683	hsa-miR-555	CLIP-seq
MIRT2203684	hsa-miR-567	CLIP-seq
MIRT2203685	hsa-miR-632	CLIP-seq
MIRT2203686	hsa-miR-654-3p	CLIP-seq
MIRT2203687	hsa-miR-9	CLIP-seq
MIRT2203687	hsa-miR-9	CLIP-seq
MIRT2506719	hsa-miR-3662	CLIP-seq
MIRT2506720	hsa-miR-4496	CLIP-seq
MIRT2203677	hsa-miR-4716-5p	CLIP-seq
MIRT2203687	hsa-miR-9	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002682	Process	Regulation of immune system process	IEA
GO:0005044	Function	Scavenger receptor activity	IDA	11564734
GO:0005044	Function	Scavenger receptor activity	TAS	11162630
GO:0005515	Function	Protein binding	IPI	22396535, 26922829, 33961781
GO:0005534	Function	Galactose binding	NAS	11564734
GO:0005581	Component	Collagen trimer	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006910	Process	Phagocytosis, recognition	IBA
GO:0006910	Process	Phagocytosis, recognition	IDA	11564734
GO:0006952	Process	Defense response	TAS	11162630
GO:0006955	Process	Immune response	IEA
GO:0009756	Process	Carbohydrate mediated signaling	NAS	11564734
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	11162630
GO:0030169	Function	Low-density lipoprotein particle binding	IBA
GO:0030169	Function	Low-density lipoprotein particle binding	IDA	11564734
GO:0030246	Function	Carbohydrate binding	IEA
GO:0030666	Component	Endocytic vesicle membrane	TAS
GO:0031012	Component	Extracellular matrix	IBA
GO:0038187	Function	Pattern recognition receptor activity	IBA
GO:0038187	Function	Pattern recognition receptor activity	IDA	11564734
GO:0042742	Process	Defense response to bacterium	IDA	11564734
GO:0044857	Process	Plasma membrane raft organization	IMP	25204797
GO:0045087	Process	Innate immune response	IEA
GO:0045087	Process	Innate immune response	TAS	11564734
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
607621	16016	ENSG00000158270

Q5KU26

Protein name

Collectin-12 (Collectin placenta protein 1) (CL-P1) (hCL-P1) (Nurse cell scavenger receptor 2) (Scavenger receptor class A member 4) (Scavenger receptor with C-type lectin)

Protein function

Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modif

PDB

2OX8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01391	Collagen	441 → 499	Collagen triple helix repeat (20 copies)	Repeat
PF01391	Collagen	530 → 589	Collagen triple helix repeat (20 copies)	Repeat
PF00059	Lectin_C	624 → 732	Lectin C-type domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in perivascular macrophages. Expressed in plaques-surrounding reactive astrocytes and in perivascular astrocytes associated with cerebral amyloid angiopathy (CAA) in the temporal cortex of Alzheimer patient (at protein level)

Sequence

MKDDFAEEEEVQSFGYKRFGIQEGTQCTKCKNNWALKFSIILLYILCALLTITVAILGYK
VVEKMDNVTGGMETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTFRSDILDLRQ
QLREITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTN
LQQDTSVLQGNLQNQMYSHNVVIMNLNNLNLTQVQQRNLITNLQRSVDDTSQAIQRIKND
FQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNSALAKANNDTLEDMNSQLNSFTGQMENI
TTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTL
TSNLNEVRTTCTDTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRLDTEVANLSVI
MEEMKLVDSKHGQLIKNFTILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGP
AGERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGSSGDPGPPGPPGKEGLPGP
QGPPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGAVVPLALQNEPTP
APEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTREEQQWIKKQMVG
RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF
QCEDVNNFICEKDRETVLSSAL

Sequence length

742

Interactions

View interactions

	KEGG		Reactome
	Phagosome		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Scavenging by Class A Receptors

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Colon adenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (52)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Acquired Kyphoscoliosis	Acquired Kyphoscoliosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Alzheimer disease	Pubtator	28630030	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Amyotrophic Lateral Sclerosis	Amyotrophic lateral sclerosis	Pubtator	40033250	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Arteriosclerosis	Arteriosclerosis	BEFREE	21723916		★★★★★ ★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia telangiectasia	Pubtator	25887408	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Atherosclerosis	BEFREE	21723916		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	36131924	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Byzanthine arch palate	High palate	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Cerebral cortical atrophy	Cerebral cortical atrophy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	37144239	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital kyphoscoliosis	Congenital kyphoscoliosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Congenital pontocerebellar hypoplasia	Pontoneocerebellar hypoplasia	GENOMICS_ENGLAND_DG	24766810		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cryptorchidism	Cryptorchidism	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	30894181	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	36131924	Inhibit	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	25819896		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetic Retinopathy	Diabetic Retinopathy	BEFREE	25819896		★★★★★ ★☆☆☆☆ Found in Text Mining only
Encephalopathies	Epileptic encephalopathy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Esotropia	Esotropia	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Exophthalmos	Proptosis	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	24532499	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulonephritis	Glomerulonephritis	Pubtator	37020564	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Glomerulonephritis IGA	Iga nephropathy	Pubtator	37020564	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Gross motor development delay	Developmental delay	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Hypoplasia of corpus callosum	Hypoplasia Of Corpus Callosum	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Mental retardation	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Medulloblastoma	Medulloblastoma	Pubtator	37083768	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	BEFREE	29212154		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metabolic Syndrome X	Metabolic Syndrome	GWASCAT_DG	29212154		★★★★★ ★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	BEFREE	24766809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	28317919		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial ischemia	Pubtator	30894181	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Myopathy	Myopathy	BEFREE	22479198		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Neurodegenerative disorder	Pubtator	32476018, 35139363	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neurodegenerative Disorders	Neurodegenerative Disorders	BEFREE	29307788		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neuromuscular Diseases	Neuromuscular Diseases	BEFREE	24766809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Nystagmus	Nystagmus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Optic Atrophy	Optic Atrophy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Pontocerebellar Hypoplasia	Pontocerebellar hypoplasia	Pubtator	36076253	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pontocerebellar hypoplasia type 10	Pontoneocerebellar hypoplasia	Orphanet			★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	ORPHANET_DG	24766809, 24766810		★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	CLINVAR_DG	24766809, 24766810		★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	GENOMICS_ENGLAND_DG	24766809, 24766810		★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	UNIPROT_DG	24766809, 24766810		★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	BEFREE	29307788		★★★★★ ★☆☆☆☆ Found in Text Mining only
PONTOCEREBELLAR HYPOPLASIA, TYPE 10	Pontoneocerebellar hypoplasia	CTD_human_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorimotor neuropathy	Sensorimotor neuropathy	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Diseases	Stomach disease	Pubtator	29491476	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	38112409	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Strabismus	Strabismus	HPO_DG			★★★★★ ★☆☆☆☆ Found in Text Mining only
Thrombosis	Thrombosis	Pubtator	34668383	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

COLEC12 (collectin subfamily member 12)