SH3BP5L (SH3 binding domain protein 5 like)

Gene

• Entrez ID: 80851
• Gene name: SH3 binding domain protein 5 like
• Gene symbol: SH3BP5L
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1q44

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT048323	hsa-miR-106a-5p	CLASH	23622248
MIRT186933	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT622296	hsa-miR-1470	HITS-CLIP	23824327
MIRT622295	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT646287	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT622294	hsa-miR-4469	HITS-CLIP	23824327
MIRT646286	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT646285	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT186933	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT622296	hsa-miR-1470	HITS-CLIP	23824327
MIRT622295	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT622294	hsa-miR-4469	HITS-CLIP	23824327
MIRT443834	hsa-miR-4319	PAR-CLIP	22100165
MIRT443833	hsa-miR-125b-5p	PAR-CLIP	22100165
MIRT443832	hsa-miR-125a-5p	PAR-CLIP	22100165
MIRT443831	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT443830	hsa-miR-345-3p	PAR-CLIP	22100165
MIRT443829	hsa-miR-4732-3p	PAR-CLIP	22100165
MIRT443828	hsa-miR-544b	PAR-CLIP	22100165
MIRT443827	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT443826	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT443825	hsa-miR-4419a	PAR-CLIP	22100165
MIRT443824	hsa-miR-4510	PAR-CLIP	22100165
MIRT443823	hsa-miR-6127	PAR-CLIP	22100165
MIRT443822	hsa-miR-6129	PAR-CLIP	22100165
MIRT443821	hsa-miR-6130	PAR-CLIP	22100165
MIRT443820	hsa-miR-6133	PAR-CLIP	22100165
MIRT443819	hsa-miR-3148	PAR-CLIP	22100165
MIRT443818	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT443817	hsa-miR-642b-5p	PAR-CLIP	22100165
MIRT443816	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT443815	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT186933	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT622296	hsa-miR-1470	HITS-CLIP	23824327
MIRT622295	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT646287	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT622294	hsa-miR-4469	HITS-CLIP	23824327
MIRT646286	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT646285	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT186933	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT622296	hsa-miR-1470	HITS-CLIP	23824327
MIRT622295	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT622294	hsa-miR-4469	HITS-CLIP	23824327
MIRT443834	hsa-miR-4319	PAR-CLIP	22100165
MIRT443833	hsa-miR-125b-5p	PAR-CLIP	22100165
MIRT443832	hsa-miR-125a-5p	PAR-CLIP	22100165
MIRT443831	hsa-miR-5584-5p	PAR-CLIP	22100165
MIRT443830	hsa-miR-345-3p	PAR-CLIP	22100165
MIRT443829	hsa-miR-4732-3p	PAR-CLIP	22100165
MIRT443828	hsa-miR-544b	PAR-CLIP	22100165
MIRT443827	hsa-miR-3126-5p	PAR-CLIP	22100165
MIRT443826	hsa-miR-6875-5p	PAR-CLIP	22100165
MIRT443825	hsa-miR-4419a	PAR-CLIP	22100165
MIRT443824	hsa-miR-4510	PAR-CLIP	22100165
MIRT443823	hsa-miR-6127	PAR-CLIP	22100165
MIRT443822	hsa-miR-6129	PAR-CLIP	22100165
MIRT443821	hsa-miR-6130	PAR-CLIP	22100165
MIRT443820	hsa-miR-6133	PAR-CLIP	22100165
MIRT443819	hsa-miR-3148	PAR-CLIP	22100165
MIRT443818	hsa-miR-4668-5p	PAR-CLIP	22100165
MIRT443817	hsa-miR-642b-5p	PAR-CLIP	22100165
MIRT443816	hsa-miR-670-5p	PAR-CLIP	22100165
MIRT443815	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT1344967	hsa-miR-125b	CLIP-seq
MIRT1344968	hsa-miR-1825	CLIP-seq
MIRT1344969	hsa-miR-2110	CLIP-seq
MIRT1344970	hsa-miR-3150a-3p	CLIP-seq
MIRT1344971	hsa-miR-331-5p	CLIP-seq
MIRT1344972	hsa-miR-3667-5p	CLIP-seq
MIRT1344973	hsa-miR-3679-3p	CLIP-seq
MIRT1344974	hsa-miR-3940-5p	CLIP-seq
MIRT1344975	hsa-miR-4260	CLIP-seq
MIRT1344976	hsa-miR-4271	CLIP-seq
MIRT1344977	hsa-miR-4287	CLIP-seq
MIRT1344978	hsa-miR-4297	CLIP-seq
MIRT1344979	hsa-miR-4305	CLIP-seq
MIRT1344980	hsa-miR-4328	CLIP-seq
MIRT1344981	hsa-miR-4507	CLIP-seq
MIRT1344982	hsa-miR-4676-5p	CLIP-seq
MIRT1344983	hsa-miR-4678	CLIP-seq
MIRT1344984	hsa-miR-4685-3p	CLIP-seq
MIRT1344985	hsa-miR-4725-3p	CLIP-seq
MIRT1344986	hsa-miR-4768-5p	CLIP-seq
MIRT1344987	hsa-miR-4777-5p	CLIP-seq
MIRT1344988	hsa-miR-515-3p	CLIP-seq
MIRT1344989	hsa-miR-518d-5p	CLIP-seq
MIRT1344990	hsa-miR-519b-5p	CLIP-seq
MIRT1344991	hsa-miR-519c-5p	CLIP-seq
MIRT1344992	hsa-miR-519e	CLIP-seq
MIRT1344993	hsa-miR-520c-5p	CLIP-seq
MIRT1344994	hsa-miR-526a	CLIP-seq
MIRT1344995	hsa-miR-548aa	CLIP-seq
MIRT1344996	hsa-miR-556-5p	CLIP-seq
MIRT1344997	hsa-miR-575	CLIP-seq
MIRT1344998	hsa-miR-622	CLIP-seq
MIRT1344999	hsa-miR-629	CLIP-seq
MIRT1345000	hsa-miR-670	CLIP-seq
MIRT2102019	hsa-miR-101	CLIP-seq
MIRT2102020	hsa-miR-103a	CLIP-seq
MIRT2102021	hsa-miR-107	CLIP-seq
MIRT2102022	hsa-miR-1203	CLIP-seq
MIRT2102023	hsa-miR-1205	CLIP-seq
MIRT2102024	hsa-miR-1207-5p	CLIP-seq
MIRT2102025	hsa-miR-1226	CLIP-seq
MIRT2102026	hsa-miR-124	CLIP-seq
MIRT2102027	hsa-miR-1286	CLIP-seq
MIRT2102028	hsa-miR-1291	CLIP-seq
MIRT2102029	hsa-miR-146b-3p	CLIP-seq
MIRT2102030	hsa-miR-150	CLIP-seq
MIRT2102031	hsa-miR-15a	CLIP-seq
MIRT2102032	hsa-miR-15b	CLIP-seq
MIRT2102033	hsa-miR-16	CLIP-seq
MIRT2102034	hsa-miR-1912	CLIP-seq
MIRT2102035	hsa-miR-194	CLIP-seq
MIRT2102036	hsa-miR-195	CLIP-seq
MIRT2102037	hsa-miR-214	CLIP-seq
MIRT2102038	hsa-miR-24	CLIP-seq
MIRT2102039	hsa-miR-2467-3p	CLIP-seq
MIRT2102040	hsa-miR-3074-5p	CLIP-seq
MIRT2102041	hsa-miR-3135b	CLIP-seq
MIRT2102042	hsa-miR-3169	CLIP-seq
MIRT2102043	hsa-miR-3170	CLIP-seq
MIRT2102044	hsa-miR-339-5p	CLIP-seq
MIRT2102045	hsa-miR-3612	CLIP-seq
MIRT2102046	hsa-miR-3619-5p	CLIP-seq
MIRT2102047	hsa-miR-3652	CLIP-seq
MIRT1344974	hsa-miR-3940-5p	CLIP-seq
MIRT2102048	hsa-miR-424	CLIP-seq
MIRT1344975	hsa-miR-4260	CLIP-seq
MIRT2102049	hsa-miR-4276	CLIP-seq
MIRT2102050	hsa-miR-4291	CLIP-seq
MIRT2102051	hsa-miR-4302	CLIP-seq
MIRT2102052	hsa-miR-4430	CLIP-seq
MIRT2102053	hsa-miR-4437	CLIP-seq
MIRT1344981	hsa-miR-4507	CLIP-seq
MIRT2102054	hsa-miR-4515	CLIP-seq
MIRT2102055	hsa-miR-4645-3p	CLIP-seq
MIRT2102056	hsa-miR-4711-3p	CLIP-seq
MIRT2102057	hsa-miR-4713-5p	CLIP-seq
MIRT2102058	hsa-miR-4763-3p	CLIP-seq
MIRT2102059	hsa-miR-4781-3p	CLIP-seq
MIRT2102060	hsa-miR-486-3p	CLIP-seq
MIRT2102061	hsa-miR-495	CLIP-seq
MIRT2102062	hsa-miR-497	CLIP-seq
MIRT2102063	hsa-miR-506	CLIP-seq
MIRT2102064	hsa-miR-5095	CLIP-seq
MIRT2102065	hsa-miR-516a-3p	CLIP-seq
MIRT2102066	hsa-miR-532-3p	CLIP-seq
MIRT2102067	hsa-miR-552	CLIP-seq
MIRT2102068	hsa-miR-571	CLIP-seq
MIRT2102069	hsa-miR-600	CLIP-seq
MIRT2102070	hsa-miR-602	CLIP-seq
MIRT2102071	hsa-miR-650	CLIP-seq
MIRT2102072	hsa-miR-761	CLIP-seq
MIRT2102073	hsa-miR-885-3p	CLIP-seq
MIRT2102074	hsa-miR-922	CLIP-seq
MIRT2102020	hsa-miR-103a	CLIP-seq
MIRT2102021	hsa-miR-107	CLIP-seq
MIRT2102023	hsa-miR-1205	CLIP-seq
MIRT2326479	hsa-miR-1207-3p	CLIP-seq
MIRT2102024	hsa-miR-1207-5p	CLIP-seq
MIRT2102025	hsa-miR-1226	CLIP-seq
MIRT2326480	hsa-miR-1283	CLIP-seq
MIRT2102027	hsa-miR-1286	CLIP-seq
MIRT2102028	hsa-miR-1291	CLIP-seq
MIRT2326481	hsa-miR-146a	CLIP-seq
MIRT2102029	hsa-miR-146b-3p	CLIP-seq
MIRT2326482	hsa-miR-146b-5p	CLIP-seq
MIRT2102030	hsa-miR-150	CLIP-seq
MIRT2102031	hsa-miR-15a	CLIP-seq
MIRT2102032	hsa-miR-15b	CLIP-seq
MIRT2102033	hsa-miR-16	CLIP-seq
MIRT2326483	hsa-miR-1915	CLIP-seq
MIRT2102036	hsa-miR-195	CLIP-seq
MIRT1344969	hsa-miR-2110	CLIP-seq
MIRT2102037	hsa-miR-214	CLIP-seq
MIRT2326484	hsa-miR-223	CLIP-seq
MIRT2102038	hsa-miR-24	CLIP-seq
MIRT2326485	hsa-miR-29a	CLIP-seq
MIRT2326486	hsa-miR-29b	CLIP-seq
MIRT2326487	hsa-miR-29c	CLIP-seq
MIRT2102040	hsa-miR-3074-5p	CLIP-seq
MIRT2102041	hsa-miR-3135b	CLIP-seq
MIRT1344970	hsa-miR-3150a-3p	CLIP-seq
MIRT2326488	hsa-miR-3154	CLIP-seq
MIRT2326489	hsa-miR-3162-3p	CLIP-seq
MIRT2326490	hsa-miR-3176	CLIP-seq
MIRT2326491	hsa-miR-3179	CLIP-seq
MIRT2326492	hsa-miR-3184	CLIP-seq
MIRT2326493	hsa-miR-3202	CLIP-seq
MIRT1344971	hsa-miR-331-5p	CLIP-seq
MIRT2102046	hsa-miR-3619-5p	CLIP-seq
MIRT2326494	hsa-miR-3650	CLIP-seq
MIRT2102047	hsa-miR-3652	CLIP-seq
MIRT2326495	hsa-miR-3663-3p	CLIP-seq
MIRT2326496	hsa-miR-3922-3p	CLIP-seq
MIRT2326497	hsa-miR-423-5p	CLIP-seq
MIRT2102048	hsa-miR-424	CLIP-seq
MIRT1344975	hsa-miR-4260	CLIP-seq
MIRT1344976	hsa-miR-4271	CLIP-seq
MIRT2102049	hsa-miR-4276	CLIP-seq
MIRT2326498	hsa-miR-4277	CLIP-seq
MIRT2102050	hsa-miR-4291	CLIP-seq
MIRT2326499	hsa-miR-4299	CLIP-seq
MIRT2102051	hsa-miR-4302	CLIP-seq
MIRT2326500	hsa-miR-4310	CLIP-seq
MIRT1344980	hsa-miR-4328	CLIP-seq
MIRT2102052	hsa-miR-4430	CLIP-seq
MIRT2326501	hsa-miR-4434	CLIP-seq
MIRT2102053	hsa-miR-4437	CLIP-seq
MIRT2326502	hsa-miR-4456	CLIP-seq
MIRT2326503	hsa-miR-4474-3p	CLIP-seq
MIRT2326504	hsa-miR-4516	CLIP-seq
MIRT2326505	hsa-miR-4531	CLIP-seq
MIRT2326506	hsa-miR-4663	CLIP-seq
MIRT2326507	hsa-miR-4677-3p	CLIP-seq
MIRT1344983	hsa-miR-4678	CLIP-seq
MIRT2326508	hsa-miR-4713-3p	CLIP-seq
MIRT2102057	hsa-miR-4713-5p	CLIP-seq
MIRT2326509	hsa-miR-4716-3p	CLIP-seq
MIRT2326510	hsa-miR-4723-5p	CLIP-seq
MIRT1344985	hsa-miR-4725-3p	CLIP-seq
MIRT2326511	hsa-miR-4726-3p	CLIP-seq
MIRT2326512	hsa-miR-4747-5p	CLIP-seq
MIRT2326513	hsa-miR-4757-5p	CLIP-seq
MIRT2102058	hsa-miR-4763-3p	CLIP-seq
MIRT2326514	hsa-miR-485-5p	CLIP-seq
MIRT2102060	hsa-miR-486-3p	CLIP-seq
MIRT2102062	hsa-miR-497	CLIP-seq
MIRT2326515	hsa-miR-5096	CLIP-seq
MIRT1344988	hsa-miR-515-3p	CLIP-seq
MIRT2102065	hsa-miR-516a-3p	CLIP-seq
MIRT1344992	hsa-miR-519e	CLIP-seq
MIRT2326516	hsa-miR-520a-5p	CLIP-seq
MIRT2326517	hsa-miR-525-5p	CLIP-seq
MIRT2102066	hsa-miR-532-3p	CLIP-seq
MIRT2326518	hsa-miR-548q	CLIP-seq
MIRT2326519	hsa-miR-589	CLIP-seq
MIRT2102070	hsa-miR-602	CLIP-seq
MIRT2326520	hsa-miR-644	CLIP-seq
MIRT2326521	hsa-miR-648	CLIP-seq
MIRT2326522	hsa-miR-759	CLIP-seq
MIRT2102072	hsa-miR-761	CLIP-seq
MIRT2102074	hsa-miR-922	CLIP-seq
MIRT2102030	hsa-miR-150	CLIP-seq
MIRT2102057	hsa-miR-4713-5p	CLIP-seq
MIRT2102066	hsa-miR-532-3p	CLIP-seq
MIRT2102020	hsa-miR-103a	CLIP-seq
MIRT2102021	hsa-miR-107	CLIP-seq
MIRT2459278	hsa-miR-3944-5p	CLIP-seq
MIRT2459279	hsa-miR-451b	CLIP-seq
MIRT2102023	hsa-miR-1205	CLIP-seq
MIRT2326479	hsa-miR-1207-3p	CLIP-seq
MIRT2102025	hsa-miR-1226	CLIP-seq
MIRT2102028	hsa-miR-1291	CLIP-seq
MIRT2102029	hsa-miR-146b-3p	CLIP-seq
MIRT2102035	hsa-miR-194	CLIP-seq
MIRT2102040	hsa-miR-3074-5p	CLIP-seq
MIRT2102041	hsa-miR-3135b	CLIP-seq
MIRT2102044	hsa-miR-339-5p	CLIP-seq
MIRT2622075	hsa-miR-3616-3p	CLIP-seq
MIRT1344975	hsa-miR-4260	CLIP-seq
MIRT2622076	hsa-miR-4436b-3p	CLIP-seq
MIRT2622077	hsa-miR-4514	CLIP-seq
MIRT2622078	hsa-miR-4633-3p	CLIP-seq
MIRT2622079	hsa-miR-4645-5p	CLIP-seq
MIRT2622080	hsa-miR-4673	CLIP-seq
MIRT2622081	hsa-miR-4692	CLIP-seq
MIRT2622082	hsa-miR-4755-3p	CLIP-seq
MIRT2102060	hsa-miR-486-3p	CLIP-seq
MIRT2622083	hsa-miR-488	CLIP-seq
MIRT2326515	hsa-miR-5096	CLIP-seq
MIRT1344988	hsa-miR-515-3p	CLIP-seq
MIRT2102065	hsa-miR-516a-3p	CLIP-seq
MIRT1344992	hsa-miR-519e	CLIP-seq
MIRT2622084	hsa-miR-558	CLIP-seq
MIRT2622085	hsa-miR-658	CLIP-seq
MIRT2326522	hsa-miR-759	CLIP-seq
MIRT2102023	hsa-miR-1205	CLIP-seq
MIRT2326479	hsa-miR-1207-3p	CLIP-seq
MIRT2102025	hsa-miR-1226	CLIP-seq
MIRT2102028	hsa-miR-1291	CLIP-seq
MIRT2102029	hsa-miR-146b-3p	CLIP-seq
MIRT2102035	hsa-miR-194	CLIP-seq
MIRT2690628	hsa-miR-296-3p	CLIP-seq
MIRT2102040	hsa-miR-3074-5p	CLIP-seq
MIRT2102041	hsa-miR-3135b	CLIP-seq
MIRT2690629	hsa-miR-3153	CLIP-seq
MIRT2326491	hsa-miR-3179	CLIP-seq
MIRT2102044	hsa-miR-339-5p	CLIP-seq
MIRT2622075	hsa-miR-3616-3p	CLIP-seq
MIRT1344975	hsa-miR-4260	CLIP-seq
MIRT2622076	hsa-miR-4436b-3p	CLIP-seq
MIRT2622077	hsa-miR-4514	CLIP-seq
MIRT2622078	hsa-miR-4633-3p	CLIP-seq
MIRT2622079	hsa-miR-4645-5p	CLIP-seq
MIRT2622080	hsa-miR-4673	CLIP-seq
MIRT2622081	hsa-miR-4692	CLIP-seq
MIRT2690630	hsa-miR-4728-3p	CLIP-seq
MIRT2622082	hsa-miR-4755-3p	CLIP-seq
MIRT2102060	hsa-miR-486-3p	CLIP-seq
MIRT2622083	hsa-miR-488	CLIP-seq
MIRT2102061	hsa-miR-495	CLIP-seq
MIRT2326515	hsa-miR-5096	CLIP-seq
MIRT1344988	hsa-miR-515-3p	CLIP-seq
MIRT2102065	hsa-miR-516a-3p	CLIP-seq
MIRT1344992	hsa-miR-519e	CLIP-seq
MIRT2622084	hsa-miR-558	CLIP-seq
MIRT2622085	hsa-miR-658	CLIP-seq
MIRT2326522	hsa-miR-759	CLIP-seq
MIRT2102073	hsa-miR-885-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004860	Function	Protein kinase inhibitor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IDA	30217979
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005515	Function	Protein binding	IPI	15161933, 28514442, 32296183, 32814053, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035556	Process	Intracellular signal transduction	IEA

Other IDs

• MIM: 620652
• HGNC: 29360
• e!Ensembl: ENSG00000175137

Protein

• UniProt ID: Q7L8J4
• Protein name: SH3 domain-binding protein 5-like (SH3BP-5-like)
• Protein function: Functions as a guanine nucleotide exchange factor (GEF) for RAB11A.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05276	SH3BP5	54 → 280	SH3 domain-binding protein 5 (SH3BP5)	Family

• Sequence:

  MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRI
  QEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEAR
  RLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKV
  NEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHK
  AKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPED
  MEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDH
  VSLDGQELGTRSGGRRGSDGGARGGRHQRSVSL

• Sequence length: 393

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OROFACIAL CLEFT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations