Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	80778
Gene name	Zinc finger protein 34
Gene symbol	ZNF34
Synonyms (NCBI Gene)	KOX32
Chromosome	8
Chromosome location	8q24.3

174

Show/Hide all (174)

miRTarBase ID	miRNA	Experiments	Reference
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677048	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679251	hsa-miR-6131	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677040	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT677039	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677048	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677040	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT677039	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT496391	hsa-miR-4326	PAR-CLIP	22291592
MIRT496390	hsa-miR-5571-3p	PAR-CLIP	22291592
MIRT496389	hsa-miR-7975	PAR-CLIP	22291592
MIRT496388	hsa-miR-384	PAR-CLIP	22291592
MIRT457576	hsa-miR-3646	PAR-CLIP	23592263
MIRT457575	hsa-miR-634	PAR-CLIP	23592263
MIRT457574	hsa-miR-3154	PAR-CLIP	23592263
MIRT457573	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT457572	hsa-miR-1321	PAR-CLIP	23592263
MIRT457571	hsa-miR-4739	PAR-CLIP	23592263
MIRT457570	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT457569	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT457568	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT457567	hsa-miR-4530	PAR-CLIP	23592263
MIRT457566	hsa-miR-3179	PAR-CLIP	23592263
MIRT457565	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT457564	hsa-miR-5093	PAR-CLIP	23592263
MIRT457563	hsa-miR-4434	PAR-CLIP	23592263
MIRT457562	hsa-miR-4516	PAR-CLIP	23592263
MIRT457561	hsa-miR-5703	PAR-CLIP	23592263
MIRT457560	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT457559	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT457558	hsa-miR-3162-5p	PAR-CLIP	23592263
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677048	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT679251	hsa-miR-6131	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677040	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT677039	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT677060	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT677059	hsa-miR-1245a	HITS-CLIP	23824327
MIRT677058	hsa-miR-8079	HITS-CLIP	23824327
MIRT677057	hsa-miR-6513-3p	HITS-CLIP	23824327
MIRT677056	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT677055	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT677054	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT677052	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT677053	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT677051	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT677050	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT677049	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT677048	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT677047	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT677046	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT677045	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT677044	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT677043	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT677042	hsa-miR-640	HITS-CLIP	23824327
MIRT677041	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT677040	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT677039	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT496391	hsa-miR-4326	PAR-CLIP	22291592
MIRT496390	hsa-miR-5571-3p	PAR-CLIP	22291592
MIRT496389	hsa-miR-7975	PAR-CLIP	22291592
MIRT496388	hsa-miR-384	PAR-CLIP	22291592
MIRT457576	hsa-miR-3646	PAR-CLIP	23592263
MIRT457575	hsa-miR-634	PAR-CLIP	23592263
MIRT457574	hsa-miR-3154	PAR-CLIP	23592263
MIRT457573	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT457572	hsa-miR-1321	PAR-CLIP	23592263
MIRT457571	hsa-miR-4739	PAR-CLIP	23592263
MIRT457570	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT457569	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT457568	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT457567	hsa-miR-4530	PAR-CLIP	23592263
MIRT457566	hsa-miR-3179	PAR-CLIP	23592263
MIRT457565	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT457564	hsa-miR-5093	PAR-CLIP	23592263
MIRT457563	hsa-miR-4434	PAR-CLIP	23592263
MIRT457562	hsa-miR-4516	PAR-CLIP	23592263
MIRT457561	hsa-miR-5703	PAR-CLIP	23592263
MIRT457560	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT457559	hsa-miR-625-5p	PAR-CLIP	23592263
MIRT457558	hsa-miR-3162-5p	PAR-CLIP	23592263

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 29892012
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
194526	13098	ENSG00000196378

Q8IZ26

Protein name

Zinc finger protein 34 (Zinc finger protein KOX32)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	34 → 75	KRAB box	Family
PF00096	zf-C2H2	195 → 217	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	251 → 273	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	279 → 301	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	307 → 329	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	335 → 357	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	363 → 385	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	391 → 413	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	419 → 441	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	447 → 469	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	475 → 498	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	503 → 525	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	531 → 553	Zinc finger, C2H2 type	Domain

Sequence

MLLLLSDQLLLTALRKPNPQAMAALFLSAPPQAEVTFEDVAVYLSREEWGRLGPAQRGLY
RDVMLETYGNLVSLGVGPAGPKPGVISQLERGDEPWVLDVQGTSGKEHLRVNSPALGTRT
EYKELTSQETFGEEDPQGSEPVEACDHISKSEGSLEKLVEQRGPRAVTLTNGESSRESGG
NLRLLSRPVPDQRPHKCDICEQSFEQRSYLNNHKRVHRSKKTNTVRNSGEIFSANLVVKE
DQKIPTGKKLHYCSYCGKTFRYSANLVKHQRLHTEEKPYKCDECGKAFSQSCEFINHRRM
HSGEIPYRCDECGKTFTRRPNLMKHQRIHTGEKPYKCGECGKHFSAYSSLIYHQRIHTGE
KPYKCNDCGKAFSDGSILIRHRRTHTGEKPFECKECGKGFTQSSNLIQHQRIHTGEKPYK
CNECEKAFIQKTKLVEHQRSHTGEKPYECNDCGKVFSQSTHLIQHQRIHTGEKPYKCSEC
GKAFHNSSRLIHHQRLHHGEKPYRCSDCKKAFSQSTYLIQHRRIHTGEKPYKCSECGKAF
RHSSNMCQHQRIHLREDFSM

Sequence length

560

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (7)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Asthma	Asthma	Pubtator	35606283	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Bipolar disorder	Pubtator	26823146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive Disorder Major	Major depressive disorder	Pubtator	26823146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	30054458		★★★★★ ★☆☆☆☆ Found in Text Mining only
Major Depressive Disorder	Mental Depression	BEFREE	26823146		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood Disorder	BEFREE	26823146		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood disorder	Pubtator	26823146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF34 (zinc finger protein 34)