AKNA (AT-hook transcription factor)

Gene

• Entrez ID: 80709
• Gene name: AT-hook transcription factor
• Gene symbol: AKNA
• Synonyms (NCBI Gene): -
• Chromosome: 9
• Chromosome location: 9q32

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT705816	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT705815	hsa-miR-3123	HITS-CLIP	23313552
MIRT705814	hsa-miR-3929	HITS-CLIP	23313552
MIRT705813	hsa-miR-4419b	HITS-CLIP	23313552
MIRT705812	hsa-miR-4478	HITS-CLIP	23313552
MIRT705811	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT705810	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT705809	hsa-miR-5690	HITS-CLIP	23313552
MIRT705808	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT705807	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT402757	hsa-miR-1827	HITS-CLIP	23313552
MIRT705806	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT705805	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT705804	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT705803	hsa-miR-31-5p	HITS-CLIP	23313552
MIRT705802	hsa-miR-7977	HITS-CLIP	23313552
MIRT705801	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT705800	hsa-miR-665	HITS-CLIP	23313552
MIRT530564	hsa-miR-6863	PAR-CLIP	22012620
MIRT530563	hsa-miR-6858-3p	PAR-CLIP	22012620
MIRT530561	hsa-miR-4676-5p	PAR-CLIP	22012620
MIRT530562	hsa-miR-575	PAR-CLIP	22012620
MIRT530560	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT735240	hsa-miR-762	Western blotting, qRT-PCR	32462010
MIRT705816	hsa-miR-34b-3p	HITS-CLIP	23313552
MIRT705815	hsa-miR-3123	HITS-CLIP	23313552
MIRT705814	hsa-miR-3929	HITS-CLIP	23313552
MIRT705813	hsa-miR-4419b	HITS-CLIP	23313552
MIRT705812	hsa-miR-4478	HITS-CLIP	23313552
MIRT705811	hsa-miR-3614-5p	HITS-CLIP	23313552
MIRT705810	hsa-miR-6500-3p	HITS-CLIP	23313552
MIRT705809	hsa-miR-5690	HITS-CLIP	23313552
MIRT705808	hsa-miR-6746-5p	HITS-CLIP	23313552
MIRT705807	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT402757	hsa-miR-1827	HITS-CLIP	23313552
MIRT705806	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT705805	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT705804	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT705803	hsa-miR-31-5p	HITS-CLIP	23313552
MIRT705802	hsa-miR-7977	HITS-CLIP	23313552
MIRT705801	hsa-miR-6771-5p	HITS-CLIP	23313552
MIRT705800	hsa-miR-665	HITS-CLIP	23313552
MIRT530564	hsa-miR-6863	PAR-CLIP	22012620
MIRT530563	hsa-miR-6858-3p	PAR-CLIP	22012620
MIRT530561	hsa-miR-4676-5p	PAR-CLIP	22012620
MIRT530562	hsa-miR-575	PAR-CLIP	22012620
MIRT530560	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT776227	hsa-miR-1207-5p	CLIP-seq
MIRT776228	hsa-miR-1266	CLIP-seq
MIRT776229	hsa-miR-185	CLIP-seq
MIRT776230	hsa-miR-196a	CLIP-seq
MIRT776231	hsa-miR-196b	CLIP-seq
MIRT776232	hsa-miR-1972	CLIP-seq
MIRT776233	hsa-miR-2355-3p	CLIP-seq
MIRT776234	hsa-miR-3120-3p	CLIP-seq
MIRT776235	hsa-miR-3121-5p	CLIP-seq
MIRT776236	hsa-miR-3168	CLIP-seq
MIRT776237	hsa-miR-3176	CLIP-seq
MIRT776238	hsa-miR-320e	CLIP-seq
MIRT776239	hsa-miR-34b	CLIP-seq
MIRT776240	hsa-miR-3646	CLIP-seq
MIRT776241	hsa-miR-3662	CLIP-seq
MIRT776242	hsa-miR-3664-3p	CLIP-seq
MIRT776243	hsa-miR-3908	CLIP-seq
MIRT776244	hsa-miR-3922-3p	CLIP-seq
MIRT776245	hsa-miR-3942-5p	CLIP-seq
MIRT776246	hsa-miR-4252	CLIP-seq
MIRT776247	hsa-miR-4276	CLIP-seq
MIRT776248	hsa-miR-4302	CLIP-seq
MIRT776249	hsa-miR-4306	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT776251	hsa-miR-450b-3p	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT776253	hsa-miR-4518	CLIP-seq
MIRT776254	hsa-miR-4537	CLIP-seq
MIRT776255	hsa-miR-4644	CLIP-seq
MIRT776256	hsa-miR-4646-3p	CLIP-seq
MIRT776257	hsa-miR-4701-5p	CLIP-seq
MIRT776258	hsa-miR-4703-5p	CLIP-seq
MIRT776259	hsa-miR-4713-3p	CLIP-seq
MIRT776260	hsa-miR-4717-5p	CLIP-seq
MIRT776261	hsa-miR-4736	CLIP-seq
MIRT776262	hsa-miR-4763-3p	CLIP-seq
MIRT776263	hsa-miR-4766-3p	CLIP-seq
MIRT776264	hsa-miR-494	CLIP-seq
MIRT776265	hsa-miR-501-5p	CLIP-seq
MIRT776266	hsa-miR-588	CLIP-seq
MIRT776267	hsa-miR-638	CLIP-seq
MIRT776268	hsa-miR-658	CLIP-seq
MIRT776269	hsa-miR-764	CLIP-seq
MIRT776270	hsa-miR-769-3p	CLIP-seq
MIRT776228	hsa-miR-1266	CLIP-seq
MIRT1545262	hsa-miR-1912	CLIP-seq
MIRT776230	hsa-miR-196a	CLIP-seq
MIRT776231	hsa-miR-196b	CLIP-seq
MIRT1545263	hsa-miR-3130-5p	CLIP-seq
MIRT776242	hsa-miR-3664-3p	CLIP-seq
MIRT1545264	hsa-miR-4482	CLIP-seq
MIRT776253	hsa-miR-4518	CLIP-seq
MIRT776227	hsa-miR-1207-5p	CLIP-seq
MIRT1929070	hsa-miR-1233	CLIP-seq
MIRT1929071	hsa-miR-125a-5p	CLIP-seq
MIRT1929072	hsa-miR-125b	CLIP-seq
MIRT1929073	hsa-miR-1275	CLIP-seq
MIRT1929074	hsa-miR-1285	CLIP-seq
MIRT1929075	hsa-miR-1291	CLIP-seq
MIRT1929076	hsa-miR-1305	CLIP-seq
MIRT1929077	hsa-miR-1343	CLIP-seq
MIRT776232	hsa-miR-1972	CLIP-seq
MIRT1929078	hsa-miR-202	CLIP-seq
MIRT1929079	hsa-miR-214	CLIP-seq
MIRT1929080	hsa-miR-2467-3p	CLIP-seq
MIRT1929081	hsa-miR-2467-5p	CLIP-seq
MIRT1929082	hsa-miR-31	CLIP-seq
MIRT1929083	hsa-miR-3122	CLIP-seq
MIRT1929084	hsa-miR-3163	CLIP-seq
MIRT1929085	hsa-miR-3180-5p	CLIP-seq
MIRT1929086	hsa-miR-3187-5p	CLIP-seq
MIRT1929087	hsa-miR-3188	CLIP-seq
MIRT1929088	hsa-miR-342-5p	CLIP-seq
MIRT776239	hsa-miR-34b	CLIP-seq
MIRT1929089	hsa-miR-3619-5p	CLIP-seq
MIRT776242	hsa-miR-3664-3p	CLIP-seq
MIRT1929090	hsa-miR-3678-3p	CLIP-seq
MIRT1929091	hsa-miR-3689a-3p	CLIP-seq
MIRT1929092	hsa-miR-3689c	CLIP-seq
MIRT1929093	hsa-miR-3907	CLIP-seq
MIRT1929094	hsa-miR-3913-5p	CLIP-seq
MIRT1929095	hsa-miR-3975	CLIP-seq
MIRT1929096	hsa-miR-410	CLIP-seq
MIRT1929097	hsa-miR-4257	CLIP-seq
MIRT1929098	hsa-miR-4291	CLIP-seq
MIRT1929099	hsa-miR-4319	CLIP-seq
MIRT1929100	hsa-miR-4419a	CLIP-seq
MIRT1929101	hsa-miR-4433	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT1929102	hsa-miR-4459	CLIP-seq
MIRT1929103	hsa-miR-4464	CLIP-seq
MIRT1929104	hsa-miR-4510	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT1929105	hsa-miR-4525	CLIP-seq
MIRT1929106	hsa-miR-4660	CLIP-seq
MIRT1929107	hsa-miR-4664-5p	CLIP-seq
MIRT1929108	hsa-miR-4665-5p	CLIP-seq
MIRT1929109	hsa-miR-4690-3p	CLIP-seq
MIRT776260	hsa-miR-4717-5p	CLIP-seq
MIRT1929110	hsa-miR-4723-5p	CLIP-seq
MIRT1929111	hsa-miR-4728-3p	CLIP-seq
MIRT1929112	hsa-miR-4728-5p	CLIP-seq
MIRT776261	hsa-miR-4736	CLIP-seq
MIRT1929113	hsa-miR-4748	CLIP-seq
MIRT776262	hsa-miR-4763-3p	CLIP-seq
MIRT1929114	hsa-miR-4768-3p	CLIP-seq
MIRT1929115	hsa-miR-483-3p	CLIP-seq
MIRT1929116	hsa-miR-510	CLIP-seq
MIRT1929117	hsa-miR-512-5p	CLIP-seq
MIRT1929118	hsa-miR-520a-5p	CLIP-seq
MIRT1929119	hsa-miR-525-5p	CLIP-seq
MIRT1929120	hsa-miR-544b	CLIP-seq
MIRT1929121	hsa-miR-548q	CLIP-seq
MIRT1929122	hsa-miR-612	CLIP-seq
MIRT1929123	hsa-miR-615-5p	CLIP-seq
MIRT1929124	hsa-miR-625	CLIP-seq
MIRT1929125	hsa-miR-646	CLIP-seq
MIRT776268	hsa-miR-658	CLIP-seq
MIRT1929126	hsa-miR-661	CLIP-seq
MIRT1929127	hsa-miR-761	CLIP-seq
MIRT1929128	hsa-miR-766	CLIP-seq
MIRT1929129	hsa-miR-922	CLIP-seq
MIRT2169763	hsa-miR-1193	CLIP-seq
MIRT776227	hsa-miR-1207-5p	CLIP-seq
MIRT1929070	hsa-miR-1233	CLIP-seq
MIRT1929071	hsa-miR-125a-5p	CLIP-seq
MIRT1929072	hsa-miR-125b	CLIP-seq
MIRT1929074	hsa-miR-1285	CLIP-seq
MIRT2169764	hsa-miR-1293	CLIP-seq
MIRT776232	hsa-miR-1972	CLIP-seq
MIRT2169765	hsa-miR-2861	CLIP-seq
MIRT2169766	hsa-miR-2964a-5p	CLIP-seq
MIRT2169767	hsa-miR-300	CLIP-seq
MIRT1929083	hsa-miR-3122	CLIP-seq
MIRT2169768	hsa-miR-3144-5p	CLIP-seq
MIRT2169769	hsa-miR-3150a-3p	CLIP-seq
MIRT2169770	hsa-miR-3158-3p	CLIP-seq
MIRT2169771	hsa-miR-3165	CLIP-seq
MIRT2169772	hsa-miR-3175	CLIP-seq
MIRT2169773	hsa-miR-3184	CLIP-seq
MIRT1929086	hsa-miR-3187-5p	CLIP-seq
MIRT2169774	hsa-miR-3191	CLIP-seq
MIRT1929088	hsa-miR-342-5p	CLIP-seq
MIRT776239	hsa-miR-34b	CLIP-seq
MIRT2169775	hsa-miR-3612	CLIP-seq
MIRT1929091	hsa-miR-3689a-3p	CLIP-seq
MIRT1929092	hsa-miR-3689c	CLIP-seq
MIRT2169776	hsa-miR-3691-5p	CLIP-seq
MIRT2169777	hsa-miR-381	CLIP-seq
MIRT2169778	hsa-miR-3909	CLIP-seq
MIRT1929094	hsa-miR-3913-5p	CLIP-seq
MIRT2169779	hsa-miR-3978	CLIP-seq
MIRT2169780	hsa-miR-423-5p	CLIP-seq
MIRT776246	hsa-miR-4252	CLIP-seq
MIRT2169781	hsa-miR-4269	CLIP-seq
MIRT2169782	hsa-miR-4292	CLIP-seq
MIRT1929099	hsa-miR-4319	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT2169783	hsa-miR-4436b-5p	CLIP-seq
MIRT2169784	hsa-miR-4483	CLIP-seq
MIRT776251	hsa-miR-450b-3p	CLIP-seq
MIRT2169785	hsa-miR-4514	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT2169786	hsa-miR-4531	CLIP-seq
MIRT776254	hsa-miR-4537	CLIP-seq
MIRT2169787	hsa-miR-4640-3p	CLIP-seq
MIRT2169788	hsa-miR-4651	CLIP-seq
MIRT2169789	hsa-miR-4652-5p	CLIP-seq
MIRT1929107	hsa-miR-4664-5p	CLIP-seq
MIRT1929109	hsa-miR-4690-3p	CLIP-seq
MIRT2169790	hsa-miR-4692	CLIP-seq
MIRT776257	hsa-miR-4701-5p	CLIP-seq
MIRT776259	hsa-miR-4713-3p	CLIP-seq
MIRT1929112	hsa-miR-4728-5p	CLIP-seq
MIRT776261	hsa-miR-4736	CLIP-seq
MIRT2169791	hsa-miR-4761-5p	CLIP-seq
MIRT776262	hsa-miR-4763-3p	CLIP-seq
MIRT2169792	hsa-miR-4802-3p	CLIP-seq
MIRT2169793	hsa-miR-491-5p	CLIP-seq
MIRT1929120	hsa-miR-544b	CLIP-seq
MIRT776266	hsa-miR-588	CLIP-seq
MIRT2169794	hsa-miR-608	CLIP-seq
MIRT1929122	hsa-miR-612	CLIP-seq
MIRT2169795	hsa-miR-624	CLIP-seq
MIRT776267	hsa-miR-638	CLIP-seq
MIRT2169796	hsa-miR-650	CLIP-seq
MIRT776268	hsa-miR-658	CLIP-seq
MIRT1929126	hsa-miR-661	CLIP-seq
MIRT776270	hsa-miR-769-3p	CLIP-seq
MIRT2169797	hsa-miR-890	CLIP-seq
MIRT2169798	hsa-miR-939	CLIP-seq
MIRT2169799	hsa-miR-940	CLIP-seq
MIRT1929076	hsa-miR-1305	CLIP-seq
MIRT1929083	hsa-miR-3122	CLIP-seq
MIRT2384052	hsa-miR-3135b	CLIP-seq
MIRT776242	hsa-miR-3664-3p	CLIP-seq
MIRT1929091	hsa-miR-3689a-3p	CLIP-seq
MIRT1929092	hsa-miR-3689c	CLIP-seq
MIRT1929094	hsa-miR-3913-5p	CLIP-seq
MIRT1929101	hsa-miR-4433	CLIP-seq
MIRT1929102	hsa-miR-4459	CLIP-seq
MIRT2384053	hsa-miR-4505	CLIP-seq
MIRT1929112	hsa-miR-4728-5p	CLIP-seq
MIRT1929114	hsa-miR-4768-3p	CLIP-seq
MIRT1929116	hsa-miR-510	CLIP-seq
MIRT1929117	hsa-miR-512-5p	CLIP-seq
MIRT2435288	hsa-miR-1234	CLIP-seq
MIRT776237	hsa-miR-3176	CLIP-seq
MIRT1929088	hsa-miR-342-5p	CLIP-seq
MIRT776244	hsa-miR-3922-3p	CLIP-seq
MIRT2435289	hsa-miR-4466	CLIP-seq
MIRT1929107	hsa-miR-4664-5p	CLIP-seq
MIRT2435290	hsa-miR-4757-5p	CLIP-seq
MIRT2435291	hsa-miR-675	CLIP-seq
MIRT2443506	hsa-miR-10a	CLIP-seq
MIRT2443507	hsa-miR-10b	CLIP-seq
MIRT2443508	hsa-miR-339-5p	CLIP-seq
MIRT2443509	hsa-miR-4421	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT2169786	hsa-miR-4531	CLIP-seq
MIRT2443510	hsa-miR-4684-5p	CLIP-seq
MIRT2169792	hsa-miR-4802-3p	CLIP-seq
MIRT2443511	hsa-miR-548c-3p	CLIP-seq
MIRT2443512	hsa-miR-593	CLIP-seq
MIRT2443506	hsa-miR-10a	CLIP-seq
MIRT2443507	hsa-miR-10b	CLIP-seq
MIRT1929079	hsa-miR-214	CLIP-seq
MIRT1929082	hsa-miR-31	CLIP-seq
MIRT1929083	hsa-miR-3122	CLIP-seq
MIRT2443508	hsa-miR-339-5p	CLIP-seq
MIRT776239	hsa-miR-34b	CLIP-seq
MIRT1929089	hsa-miR-3619-5p	CLIP-seq
MIRT1929091	hsa-miR-3689a-3p	CLIP-seq
MIRT1929092	hsa-miR-3689c	CLIP-seq
MIRT1929094	hsa-miR-3913-5p	CLIP-seq
MIRT1929098	hsa-miR-4291	CLIP-seq
MIRT2443509	hsa-miR-4421	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT2169786	hsa-miR-4531	CLIP-seq
MIRT1929106	hsa-miR-4660	CLIP-seq
MIRT2443510	hsa-miR-4684-5p	CLIP-seq
MIRT1929109	hsa-miR-4690-3p	CLIP-seq
MIRT1929112	hsa-miR-4728-5p	CLIP-seq
MIRT2169792	hsa-miR-4802-3p	CLIP-seq
MIRT1929115	hsa-miR-483-3p	CLIP-seq
MIRT2443511	hsa-miR-548c-3p	CLIP-seq
MIRT2443512	hsa-miR-593	CLIP-seq
MIRT1929125	hsa-miR-646	CLIP-seq
MIRT1929127	hsa-miR-761	CLIP-seq
MIRT1929128	hsa-miR-766	CLIP-seq
MIRT1929129	hsa-miR-922	CLIP-seq
MIRT2443506	hsa-miR-10a	CLIP-seq
MIRT2443507	hsa-miR-10b	CLIP-seq
MIRT1929079	hsa-miR-214	CLIP-seq
MIRT1929082	hsa-miR-31	CLIP-seq
MIRT1929083	hsa-miR-3122	CLIP-seq
MIRT776238	hsa-miR-320e	CLIP-seq
MIRT2443508	hsa-miR-339-5p	CLIP-seq
MIRT776239	hsa-miR-34b	CLIP-seq
MIRT1929089	hsa-miR-3619-5p	CLIP-seq
MIRT1929091	hsa-miR-3689a-3p	CLIP-seq
MIRT1929092	hsa-miR-3689c	CLIP-seq
MIRT1929094	hsa-miR-3913-5p	CLIP-seq
MIRT776246	hsa-miR-4252	CLIP-seq
MIRT1929098	hsa-miR-4291	CLIP-seq
MIRT2443509	hsa-miR-4421	CLIP-seq
MIRT776250	hsa-miR-4434	CLIP-seq
MIRT776251	hsa-miR-450b-3p	CLIP-seq
MIRT776252	hsa-miR-4516	CLIP-seq
MIRT2169786	hsa-miR-4531	CLIP-seq
MIRT1929106	hsa-miR-4660	CLIP-seq
MIRT2443510	hsa-miR-4684-5p	CLIP-seq
MIRT1929109	hsa-miR-4690-3p	CLIP-seq
MIRT776259	hsa-miR-4713-3p	CLIP-seq
MIRT1929112	hsa-miR-4728-5p	CLIP-seq
MIRT2169792	hsa-miR-4802-3p	CLIP-seq
MIRT1929115	hsa-miR-483-3p	CLIP-seq
MIRT2443511	hsa-miR-548c-3p	CLIP-seq
MIRT2443512	hsa-miR-593	CLIP-seq
MIRT776267	hsa-miR-638	CLIP-seq
MIRT1929125	hsa-miR-646	CLIP-seq
MIRT1929127	hsa-miR-761	CLIP-seq
MIRT1929128	hsa-miR-766	CLIP-seq
MIRT776270	hsa-miR-769-3p	CLIP-seq
MIRT1929129	hsa-miR-922	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001650	Component	Fibrillar center	IDA
GO:0001837	Process	Epithelial to mesenchymal transition	IBA
GO:0001837	Process	Epithelial to mesenchymal transition	IEA
GO:0001837	Process	Epithelial to mesenchymal transition	ISS
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	16000308, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA
GO:0005813	Component	Centrosome	IEA
GO:0005814	Component	Centriole	IEA
GO:0005814	Component	Centriole	ISS
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005874	Component	Microtubule	ISS
GO:0007399	Process	Nervous system development	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0021849	Process	Neuroblast division in subventricular zone	IBA
GO:0021849	Process	Neuroblast division in subventricular zone	IEA
GO:0021849	Process	Neuroblast division in subventricular zone	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	11268217
GO:0050727	Process	Regulation of inflammatory response	IEA
GO:0050727	Process	Regulation of inflammatory response	ISS
GO:0060232	Process	Delamination	IEA
GO:0060232	Process	Delamination	ISS
GO:0060234	Process	Neuroblast delamination	IBA
GO:0060234	Process	Neuroblast delamination	IEA
GO:0060234	Process	Neuroblast delamination	ISS

Other IDs

• MIM: 605729
• HGNC: 24108
• e!Ensembl: ENSG00000106948

Protein

• UniProt ID: Q7Z591
• Protein name: Microtubule organization protein AKNA (AT-hook-containing transcription factor)
• Protein function: Centrosomal protein that plays a key role in cell delamination by regulating microtubule organization (By similarity). Required for the delamination and retention of neural stem cells from the subventricular zone during neurogenesis (By similari
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12443	AKNA	598 → 696	AT-hook-containing transcription factor	Family

• Tissue specificity: TISSUE SPECIFICITY: Predominantly expressed by lymphoid tissues. Highly expressed in the spleen, lymph nodes and peripheral blood leukocytes, expressed at lower level in the thymus. Mainly expressed by germinal center B-lymphocytes, a stage in which recep
• Sequence:

  MASSETEIRWAEPGLGKGPQRRRWAWAEDKRDVDRSSSQSWEEERLFPNATSPELLEDFR
  LAQQHLPPLEWDPHPQPDGHQDSESGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDM
  TEEEPDGTLGSLEVEEAGESSSRLGYEAGLSLEGHGNTSPMALGHGQARGWVASGEQASG
  DKLSEHSEVNPSVELSPARSWSSGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPS
  HHLLSPDGRTGGSVARATPMEFQDSSAPPAQSPQHATDRWRRETTRFFCPQPKEHIWKQT
  KTSPKPLPSRFIGSISPLNPQPRPTRQGRPLPRQGATLAGRSSSNAPKYGRGQLNYPLPD
  FSKVGPRVRFPKDESYRPPKSRSHNRKPQAPARPLIFKSPAEIVQEVLLSSGEAALAKDT
  PPAHPITRVPQEFQTPEQATELVHQLQEDYHRLLTKYAEAENTIDQLRLGAKVNLFSDPP
  QPNHSIHTGMVPQGTKVLSFTIPQPRSAEWWPGPAEDPQASAASGWPSARGDLSPSSLTS
  MPTLGWLPENRDISEDQSSAEQTQALASQASQFLAKVESFERLIQAGRLMPQDQVKGFQR
  LKAAHAALEEEYLKACREQHPAQPLAGSKGTPGRFDPRRELEAEIYRLGSCLEELKEHID
  QTQQEPEPPGSDSALDSTPALPCLHQPTHLPAPSGQAPMPAIKTSCPEPATTTAAASTGP
  CPLHVNVEVSSGNSEVEDRPQDPLARLRHKELQMEQVYHGLMERYLSVKSLPEAMRMEEE
  EEGEEEEEEEGGGDSLEVDGVAATPGKAEATRVLPRQCPVQAEKSHGAPLEEATEKMVSM
  KPPGFQASLARDGHMSGLGKAEAAPPGPGVPPHPPGTKSAASHQSSMTSLEGSGISERLP
  QKPLHRGGGPHLEETWMASPETDSGFVGSETSRVSPLTQTPEHRLSHISTAGTLAQPFAA
  SVPRDGASYPKARGSLIPRRATEPSTPRSQAQRYLSSPSGPLRQRAPNFSLERTLAAEMA
  VPGSEFEGHKRISEQPLPNKTISPPPAPAPAAAPLPCGPTETIPSFLLTRAGRDQAICEL
  QEEVSRLRLRLEDSLHQPLQGSPTRPASAFDRPARTRGRPADSPATWGSHYGSKSTERLP
  GEPRGEEQIVPPGRQRARSSSVPREVLRLSLSSESELPSLPLFSEKSKTTKDSPQAARDG
  KRGVGSAGWPDRVTFRGQYTGHEYHVLSPKAVPKGNGTVSCPHCRPIRTQDAGGAVTGDP
  LGPPPADTLQCPLCGQVGSPPEADGPGSATSGAEKATTRRKASSTPSPKQRSKQAGSSPR
  PPPGLWYLATAPPAPAPPAFAYISSVPIMPYPPAAVYYAPAGPTSAQPAAKWPPTASPPP
  ARRHRHSIQLDLGDLEELNKALSRAVQAAESVRSTTRQMRSSLSADLRQAHSLRGSCLF

• Sequence length: 1439

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
AKNA-related autism spectrum disorder	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NON-ALCOHOLIC FATTY LIVER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
cervical cancer	Cervical Cancer	BEFREE	20507260, 30562965		★☆☆☆☆ Found in Text Mining only
Cervix carcinoma	Cervix carcinoma	BEFREE	20507260, 30562965		★☆☆☆☆ Found in Text Mining only
Intellectual Disability	Intellectual developmental disorder	Pubtator	34680889	Associate	★☆☆☆☆ Found in Text Mining only
Isolated somatotropin deficiency	Isolated Somatotropin Deficiency	BEFREE	29079362		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	21224353		★☆☆☆☆ Found in Text Mining only
Malignant tumor of cervix	Cervical Tumor	BEFREE	20507260, 30562965		★☆☆☆☆ Found in Text Mining only
Microcephaly	Microcephaly	Pubtator	34680889	Associate	★☆☆☆☆ Found in Text Mining only
Osteoarthritis, Knee	Knee osteoarthritis	BEFREE	29368274		★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	39348329	Associate	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	Pubtator	37552420	Associate	★☆☆☆☆ Found in Text Mining only
Sjogren's Syndrome	Sjogren syndrome	Pubtator	28484714	Associate	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	32462010	Associate	★☆☆☆☆ Found in Text Mining only
Uveomeningoencephalitic Syndrome	Uveomeningoencephalitic syndrome	Pubtator	21297967	Inhibit	★☆☆☆☆ Found in Text Mining only