CUL5 (cullin 5)

Gene

• Entrez ID: 8065
• Gene name: Cullin 5
• Gene symbol: CUL5
• Synonyms (NCBI Gene): CUL-5, VACM-1, VACM1
• Chromosome: 11
• Chromosome location: 11q22.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004846	hsa-miR-192-5p	Luciferase reporter assay, qRT-PCR, Western blot	19074876
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006475	hsa-miR-19a-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT006476	hsa-miR-19b-3p	qRT-PCR, Western blot	22561557
MIRT019403	hsa-miR-148b-3p	Microarray	17612493
MIRT019963	hsa-miR-375	Microarray	20215506
MIRT024359	hsa-miR-215-5p	Microarray	19074876
MIRT004846	hsa-miR-192-5p	Reporter assay;Western blot;Microarray;Other	19074876
MIRT049218	hsa-miR-92a-3p	CLASH	23622248
MIRT048574	hsa-miR-100-5p	CLASH	23622248
MIRT042216	hsa-miR-484	CLASH	23622248
MIRT438162	hsa-miR-7-5p	Flow, GFP reporter assay, qRT-PCR, Western blot	24339204
MIRT438162	hsa-miR-7-5p	Flow, GFP reporter assay, qRT-PCR, Western blot	24339204
MIRT440855	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT440854	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT440855	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT128339	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT128340	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT128341	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT128346	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT440854	hsa-miR-205-5p	HITS-CLIP	22473208
MIRT916703	hsa-miR-1205	CLIP-seq
MIRT916704	hsa-miR-1238	CLIP-seq
MIRT916705	hsa-miR-1256	CLIP-seq
MIRT916706	hsa-miR-1271	CLIP-seq
MIRT916707	hsa-miR-148a	CLIP-seq
MIRT916708	hsa-miR-148b	CLIP-seq
MIRT916709	hsa-miR-152	CLIP-seq
MIRT916710	hsa-miR-154	CLIP-seq
MIRT916711	hsa-miR-182	CLIP-seq
MIRT916712	hsa-miR-188-5p	CLIP-seq
MIRT916713	hsa-miR-1913	CLIP-seq
MIRT916714	hsa-miR-19a	CLIP-seq
MIRT916715	hsa-miR-19b	CLIP-seq
MIRT916716	hsa-miR-3074-5p	CLIP-seq
MIRT916717	hsa-miR-3121-5p	CLIP-seq
MIRT916718	hsa-miR-3124-3p	CLIP-seq
MIRT916719	hsa-miR-3145-5p	CLIP-seq
MIRT916720	hsa-miR-3149	CLIP-seq
MIRT916721	hsa-miR-3160-5p	CLIP-seq
MIRT916722	hsa-miR-3161	CLIP-seq
MIRT916723	hsa-miR-3180-5p	CLIP-seq
MIRT916724	hsa-miR-3182	CLIP-seq
MIRT916725	hsa-miR-3200-5p	CLIP-seq
MIRT916726	hsa-miR-324-3p	CLIP-seq
MIRT916727	hsa-miR-337-3p	CLIP-seq
MIRT916728	hsa-miR-3613-3p	CLIP-seq
MIRT916729	hsa-miR-3646	CLIP-seq
MIRT916730	hsa-miR-3665	CLIP-seq
MIRT916731	hsa-miR-3667-3p	CLIP-seq
MIRT916732	hsa-miR-3942-3p	CLIP-seq
MIRT916733	hsa-miR-3977	CLIP-seq
MIRT916734	hsa-miR-423-3p	CLIP-seq
MIRT916735	hsa-miR-4276	CLIP-seq
MIRT916736	hsa-miR-4307	CLIP-seq
MIRT916737	hsa-miR-4310	CLIP-seq
MIRT916738	hsa-miR-4418	CLIP-seq
MIRT916739	hsa-miR-4437	CLIP-seq
MIRT916740	hsa-miR-4506	CLIP-seq
MIRT916741	hsa-miR-4642	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT916743	hsa-miR-4674	CLIP-seq
MIRT916744	hsa-miR-4691-5p	CLIP-seq
MIRT916745	hsa-miR-4699-5p	CLIP-seq
MIRT916746	hsa-miR-4727-5p	CLIP-seq
MIRT916747	hsa-miR-4773	CLIP-seq
MIRT916748	hsa-miR-502-5p	CLIP-seq
MIRT916749	hsa-miR-509-3-5p	CLIP-seq
MIRT916750	hsa-miR-509-5p	CLIP-seq
MIRT916751	hsa-miR-5096	CLIP-seq
MIRT916752	hsa-miR-544	CLIP-seq
MIRT916753	hsa-miR-548a-3p	CLIP-seq
MIRT916754	hsa-miR-548e	CLIP-seq
MIRT916755	hsa-miR-548f	CLIP-seq
MIRT916756	hsa-miR-548n	CLIP-seq
MIRT916757	hsa-miR-548t	CLIP-seq
MIRT916758	hsa-miR-561	CLIP-seq
MIRT916759	hsa-miR-568	CLIP-seq
MIRT916760	hsa-miR-590-3p	CLIP-seq
MIRT916761	hsa-miR-595	CLIP-seq
MIRT916762	hsa-miR-657	CLIP-seq
MIRT916763	hsa-miR-96	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT1971916	hsa-miR-124	CLIP-seq
MIRT1971917	hsa-miR-1323	CLIP-seq
MIRT1971918	hsa-miR-145	CLIP-seq
MIRT916707	hsa-miR-148a	CLIP-seq
MIRT916708	hsa-miR-148b	CLIP-seq
MIRT916709	hsa-miR-152	CLIP-seq
MIRT1971919	hsa-miR-181a	CLIP-seq
MIRT1971920	hsa-miR-181b	CLIP-seq
MIRT1971921	hsa-miR-181c	CLIP-seq
MIRT1971922	hsa-miR-181d	CLIP-seq
MIRT1971923	hsa-miR-1976	CLIP-seq
MIRT916714	hsa-miR-19a	CLIP-seq
MIRT916715	hsa-miR-19b	CLIP-seq
MIRT1971924	hsa-miR-214	CLIP-seq
MIRT1971925	hsa-miR-2682	CLIP-seq
MIRT1971926	hsa-miR-3120-5p	CLIP-seq
MIRT916718	hsa-miR-3124-3p	CLIP-seq
MIRT916721	hsa-miR-3160-5p	CLIP-seq
MIRT916725	hsa-miR-3200-5p	CLIP-seq
MIRT1971927	hsa-miR-3619-5p	CLIP-seq
MIRT916729	hsa-miR-3646	CLIP-seq
MIRT1971928	hsa-miR-3664-5p	CLIP-seq
MIRT916731	hsa-miR-3667-3p	CLIP-seq
MIRT1971929	hsa-miR-3668	CLIP-seq
MIRT1971930	hsa-miR-3677-5p	CLIP-seq
MIRT1971931	hsa-miR-3686	CLIP-seq
MIRT1971932	hsa-miR-3714	CLIP-seq
MIRT1971933	hsa-miR-380	CLIP-seq
MIRT1971934	hsa-miR-3910	CLIP-seq
MIRT1971935	hsa-miR-3935	CLIP-seq
MIRT1971936	hsa-miR-409-3p	CLIP-seq
MIRT1971937	hsa-miR-4262	CLIP-seq
MIRT1971938	hsa-miR-4264	CLIP-seq
MIRT916735	hsa-miR-4276	CLIP-seq
MIRT1971939	hsa-miR-4282	CLIP-seq
MIRT1971940	hsa-miR-4291	CLIP-seq
MIRT916737	hsa-miR-4310	CLIP-seq
MIRT1971941	hsa-miR-449c	CLIP-seq
MIRT1971942	hsa-miR-450b-5p	CLIP-seq
MIRT1971943	hsa-miR-4514	CLIP-seq
MIRT1971944	hsa-miR-4519	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT1971945	hsa-miR-4668-3p	CLIP-seq
MIRT1971946	hsa-miR-4690-5p	CLIP-seq
MIRT1971947	hsa-miR-4692	CLIP-seq
MIRT1971948	hsa-miR-4696	CLIP-seq
MIRT1971949	hsa-miR-4698	CLIP-seq
MIRT916745	hsa-miR-4699-5p	CLIP-seq
MIRT1971950	hsa-miR-4719	CLIP-seq
MIRT1971951	hsa-miR-4753-3p	CLIP-seq
MIRT1971952	hsa-miR-4768-5p	CLIP-seq
MIRT1971953	hsa-miR-4797-3p	CLIP-seq
MIRT916748	hsa-miR-502-5p	CLIP-seq
MIRT1971954	hsa-miR-506	CLIP-seq
MIRT1971955	hsa-miR-507	CLIP-seq
MIRT1971956	hsa-miR-508-5p	CLIP-seq
MIRT1971957	hsa-miR-513b	CLIP-seq
MIRT916753	hsa-miR-548a-3p	CLIP-seq
MIRT1971958	hsa-miR-548ae	CLIP-seq
MIRT1971959	hsa-miR-548ag	CLIP-seq
MIRT1971960	hsa-miR-548ai	CLIP-seq
MIRT1971961	hsa-miR-548aj	CLIP-seq
MIRT1971962	hsa-miR-548am	CLIP-seq
MIRT916754	hsa-miR-548e	CLIP-seq
MIRT916755	hsa-miR-548f	CLIP-seq
MIRT1971963	hsa-miR-548o	CLIP-seq
MIRT1971964	hsa-miR-548x	CLIP-seq
MIRT1971965	hsa-miR-550b	CLIP-seq
MIRT1971966	hsa-miR-557	CLIP-seq
MIRT916758	hsa-miR-561	CLIP-seq
MIRT1971967	hsa-miR-582-5p	CLIP-seq
MIRT1971968	hsa-miR-761	CLIP-seq
MIRT1971969	hsa-miR-922	CLIP-seq
MIRT1971917	hsa-miR-1323	CLIP-seq
MIRT1971918	hsa-miR-145	CLIP-seq
MIRT916707	hsa-miR-148a	CLIP-seq
MIRT916708	hsa-miR-148b	CLIP-seq
MIRT916709	hsa-miR-152	CLIP-seq
MIRT1971919	hsa-miR-181a	CLIP-seq
MIRT1971920	hsa-miR-181b	CLIP-seq
MIRT1971921	hsa-miR-181c	CLIP-seq
MIRT1971922	hsa-miR-181d	CLIP-seq
MIRT916712	hsa-miR-188-5p	CLIP-seq
MIRT916714	hsa-miR-19a	CLIP-seq
MIRT916715	hsa-miR-19b	CLIP-seq
MIRT1971924	hsa-miR-214	CLIP-seq
MIRT2207582	hsa-miR-217	CLIP-seq
MIRT2207583	hsa-miR-2278	CLIP-seq
MIRT1971925	hsa-miR-2682	CLIP-seq
MIRT2207584	hsa-miR-3074-3p	CLIP-seq
MIRT2207585	hsa-miR-3120-3p	CLIP-seq
MIRT916718	hsa-miR-3124-3p	CLIP-seq
MIRT2207586	hsa-miR-3143	CLIP-seq
MIRT916721	hsa-miR-3160-5p	CLIP-seq
MIRT916725	hsa-miR-3200-5p	CLIP-seq
MIRT2207587	hsa-miR-361-5p	CLIP-seq
MIRT1971927	hsa-miR-3619-5p	CLIP-seq
MIRT2207588	hsa-miR-3658	CLIP-seq
MIRT916731	hsa-miR-3667-3p	CLIP-seq
MIRT1971929	hsa-miR-3668	CLIP-seq
MIRT1971930	hsa-miR-3677-5p	CLIP-seq
MIRT1971933	hsa-miR-380	CLIP-seq
MIRT2207589	hsa-miR-3908	CLIP-seq
MIRT916732	hsa-miR-3942-3p	CLIP-seq
MIRT916734	hsa-miR-423-3p	CLIP-seq
MIRT1971937	hsa-miR-4262	CLIP-seq
MIRT1971938	hsa-miR-4264	CLIP-seq
MIRT916735	hsa-miR-4276	CLIP-seq
MIRT2207590	hsa-miR-4280	CLIP-seq
MIRT1971939	hsa-miR-4282	CLIP-seq
MIRT1971940	hsa-miR-4291	CLIP-seq
MIRT916736	hsa-miR-4307	CLIP-seq
MIRT916737	hsa-miR-4310	CLIP-seq
MIRT916738	hsa-miR-4418	CLIP-seq
MIRT1971941	hsa-miR-449c	CLIP-seq
MIRT1971942	hsa-miR-450b-5p	CLIP-seq
MIRT1971943	hsa-miR-4514	CLIP-seq
MIRT1971945	hsa-miR-4668-3p	CLIP-seq
MIRT1971946	hsa-miR-4690-5p	CLIP-seq
MIRT1971947	hsa-miR-4692	CLIP-seq
MIRT1971948	hsa-miR-4696	CLIP-seq
MIRT1971949	hsa-miR-4698	CLIP-seq
MIRT916745	hsa-miR-4699-5p	CLIP-seq
MIRT2207591	hsa-miR-4795-3p	CLIP-seq
MIRT1971953	hsa-miR-4797-3p	CLIP-seq
MIRT916748	hsa-miR-502-5p	CLIP-seq
MIRT1971955	hsa-miR-507	CLIP-seq
MIRT1971956	hsa-miR-508-5p	CLIP-seq
MIRT916749	hsa-miR-509-3-5p	CLIP-seq
MIRT916750	hsa-miR-509-5p	CLIP-seq
MIRT2207592	hsa-miR-543	CLIP-seq
MIRT1971963	hsa-miR-548o	CLIP-seq
MIRT1971966	hsa-miR-557	CLIP-seq
MIRT916758	hsa-miR-561	CLIP-seq
MIRT2207593	hsa-miR-579	CLIP-seq
MIRT916760	hsa-miR-590-3p	CLIP-seq
MIRT916761	hsa-miR-595	CLIP-seq
MIRT1971968	hsa-miR-761	CLIP-seq
MIRT1971969	hsa-miR-922	CLIP-seq
MIRT2207594	hsa-miR-935	CLIP-seq
MIRT2207583	hsa-miR-2278	CLIP-seq
MIRT2207584	hsa-miR-3074-3p	CLIP-seq
MIRT916723	hsa-miR-3180-5p	CLIP-seq
MIRT2207587	hsa-miR-361-5p	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT2386591	hsa-miR-4722-5p	CLIP-seq
MIRT2386592	hsa-miR-4768-3p	CLIP-seq
MIRT2386593	hsa-miR-488	CLIP-seq
MIRT916706	hsa-miR-1271	CLIP-seq
MIRT916711	hsa-miR-182	CLIP-seq
MIRT916763	hsa-miR-96	CLIP-seq
MIRT916706	hsa-miR-1271	CLIP-seq
MIRT916711	hsa-miR-182	CLIP-seq
MIRT916763	hsa-miR-96	CLIP-seq
MIRT2447820	hsa-miR-513a-3p	CLIP-seq
MIRT2447821	hsa-miR-548a-5p	CLIP-seq
MIRT2447822	hsa-miR-548ab	CLIP-seq
MIRT2447823	hsa-miR-548ak	CLIP-seq
MIRT2447824	hsa-miR-548b-5p	CLIP-seq
MIRT2447825	hsa-miR-548c-5p	CLIP-seq
MIRT2447826	hsa-miR-548d-5p	CLIP-seq
MIRT2447827	hsa-miR-548h	CLIP-seq
MIRT2447828	hsa-miR-548i	CLIP-seq
MIRT2447829	hsa-miR-548j	CLIP-seq
MIRT916756	hsa-miR-548n	CLIP-seq
MIRT2447830	hsa-miR-548w	CLIP-seq
MIRT2447831	hsa-miR-548y	CLIP-seq
MIRT2447832	hsa-miR-559	CLIP-seq
MIRT2447820	hsa-miR-513a-3p	CLIP-seq
MIRT2447821	hsa-miR-548a-5p	CLIP-seq
MIRT2447822	hsa-miR-548ab	CLIP-seq
MIRT2447823	hsa-miR-548ak	CLIP-seq
MIRT2447824	hsa-miR-548b-5p	CLIP-seq
MIRT2447825	hsa-miR-548c-5p	CLIP-seq
MIRT2447826	hsa-miR-548d-5p	CLIP-seq
MIRT2447827	hsa-miR-548h	CLIP-seq
MIRT2447828	hsa-miR-548i	CLIP-seq
MIRT2447829	hsa-miR-548j	CLIP-seq
MIRT916756	hsa-miR-548n	CLIP-seq
MIRT2447830	hsa-miR-548w	CLIP-seq
MIRT2447831	hsa-miR-548y	CLIP-seq
MIRT2447832	hsa-miR-559	CLIP-seq
MIRT2510869	hsa-miR-1183	CLIP-seq
MIRT2510870	hsa-miR-1229	CLIP-seq
MIRT2510871	hsa-miR-1237	CLIP-seq
MIRT916706	hsa-miR-1271	CLIP-seq
MIRT2510872	hsa-miR-1283	CLIP-seq
MIRT2510873	hsa-miR-136	CLIP-seq
MIRT2510874	hsa-miR-146a	CLIP-seq
MIRT2510875	hsa-miR-146b-5p	CLIP-seq
MIRT916711	hsa-miR-182	CLIP-seq
MIRT2510876	hsa-miR-1912	CLIP-seq
MIRT2510877	hsa-miR-194	CLIP-seq
MIRT2510878	hsa-miR-200b	CLIP-seq
MIRT2510879	hsa-miR-200c	CLIP-seq
MIRT2510880	hsa-miR-221	CLIP-seq
MIRT2510881	hsa-miR-222	CLIP-seq
MIRT2510882	hsa-miR-2467-5p	CLIP-seq
MIRT2207585	hsa-miR-3120-3p	CLIP-seq
MIRT916719	hsa-miR-3145-5p	CLIP-seq
MIRT2510883	hsa-miR-3146	CLIP-seq
MIRT2510884	hsa-miR-3157-3p	CLIP-seq
MIRT2510885	hsa-miR-3188	CLIP-seq
MIRT2510886	hsa-miR-324-5p	CLIP-seq
MIRT2510887	hsa-miR-3607-3p	CLIP-seq
MIRT916728	hsa-miR-3613-3p	CLIP-seq
MIRT2510888	hsa-miR-3617	CLIP-seq
MIRT2207588	hsa-miR-3658	CLIP-seq
MIRT2510889	hsa-miR-3682-5p	CLIP-seq
MIRT2510890	hsa-miR-3685	CLIP-seq
MIRT1971931	hsa-miR-3686	CLIP-seq
MIRT2510891	hsa-miR-369-3p	CLIP-seq
MIRT1971933	hsa-miR-380	CLIP-seq
MIRT2510892	hsa-miR-384	CLIP-seq
MIRT2510893	hsa-miR-3975	CLIP-seq
MIRT1971936	hsa-miR-409-3p	CLIP-seq
MIRT2510894	hsa-miR-4256	CLIP-seq
MIRT1971939	hsa-miR-4282	CLIP-seq
MIRT2510895	hsa-miR-429	CLIP-seq
MIRT2510896	hsa-miR-4297	CLIP-seq
MIRT916737	hsa-miR-4310	CLIP-seq
MIRT2510897	hsa-miR-4423-5p	CLIP-seq
MIRT2510898	hsa-miR-4468	CLIP-seq
MIRT2510899	hsa-miR-4494	CLIP-seq
MIRT2510900	hsa-miR-4499	CLIP-seq
MIRT1971944	hsa-miR-4519	CLIP-seq
MIRT2510901	hsa-miR-4633-5p	CLIP-seq
MIRT2510902	hsa-miR-4649-3p	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT2510903	hsa-miR-4662a-3p	CLIP-seq
MIRT2510904	hsa-miR-4666-5p	CLIP-seq
MIRT2510905	hsa-miR-4670-3p	CLIP-seq
MIRT1971950	hsa-miR-4719	CLIP-seq
MIRT2510906	hsa-miR-4760-3p	CLIP-seq
MIRT2510907	hsa-miR-4762-5p	CLIP-seq
MIRT916747	hsa-miR-4773	CLIP-seq
MIRT2510908	hsa-miR-4786-5p	CLIP-seq
MIRT2510909	hsa-miR-4803	CLIP-seq
MIRT2510910	hsa-miR-485-5p	CLIP-seq
MIRT2386593	hsa-miR-488	CLIP-seq
MIRT1971956	hsa-miR-508-5p	CLIP-seq
MIRT916751	hsa-miR-5096	CLIP-seq
MIRT1971957	hsa-miR-513b	CLIP-seq
MIRT2510911	hsa-miR-532-5p	CLIP-seq
MIRT2510912	hsa-miR-544b	CLIP-seq
MIRT916753	hsa-miR-548a-3p	CLIP-seq
MIRT2510913	hsa-miR-548aa	CLIP-seq
MIRT2510914	hsa-miR-548ac	CLIP-seq
MIRT2510915	hsa-miR-548c-3p	CLIP-seq
MIRT2510916	hsa-miR-548d-3p	CLIP-seq
MIRT916754	hsa-miR-548e	CLIP-seq
MIRT916755	hsa-miR-548f	CLIP-seq
MIRT2510917	hsa-miR-548p	CLIP-seq
MIRT2510918	hsa-miR-548v	CLIP-seq
MIRT2510919	hsa-miR-548z	CLIP-seq
MIRT2510920	hsa-miR-589	CLIP-seq
MIRT2510921	hsa-miR-605	CLIP-seq
MIRT2510922	hsa-miR-641	CLIP-seq
MIRT2510923	hsa-miR-7	CLIP-seq
MIRT2510924	hsa-miR-769-5p	CLIP-seq
MIRT2510925	hsa-miR-874	CLIP-seq
MIRT2207594	hsa-miR-935	CLIP-seq
MIRT2510926	hsa-miR-938	CLIP-seq
MIRT916763	hsa-miR-96	CLIP-seq
MIRT2510869	hsa-miR-1183	CLIP-seq
MIRT2510872	hsa-miR-1283	CLIP-seq
MIRT2510873	hsa-miR-136	CLIP-seq
MIRT2510874	hsa-miR-146a	CLIP-seq
MIRT2510875	hsa-miR-146b-5p	CLIP-seq
MIRT2510877	hsa-miR-194	CLIP-seq
MIRT2510878	hsa-miR-200b	CLIP-seq
MIRT2510879	hsa-miR-200c	CLIP-seq
MIRT2510882	hsa-miR-2467-5p	CLIP-seq
MIRT916719	hsa-miR-3145-5p	CLIP-seq
MIRT2510885	hsa-miR-3188	CLIP-seq
MIRT2510886	hsa-miR-324-5p	CLIP-seq
MIRT916728	hsa-miR-3613-3p	CLIP-seq
MIRT2510888	hsa-miR-3617	CLIP-seq
MIRT2207588	hsa-miR-3658	CLIP-seq
MIRT2510890	hsa-miR-3685	CLIP-seq
MIRT1971931	hsa-miR-3686	CLIP-seq
MIRT2510891	hsa-miR-369-3p	CLIP-seq
MIRT1971933	hsa-miR-380	CLIP-seq
MIRT2510892	hsa-miR-384	CLIP-seq
MIRT2510893	hsa-miR-3975	CLIP-seq
MIRT1971936	hsa-miR-409-3p	CLIP-seq
MIRT2510895	hsa-miR-429	CLIP-seq
MIRT2510901	hsa-miR-4633-5p	CLIP-seq
MIRT2510902	hsa-miR-4649-3p	CLIP-seq
MIRT916742	hsa-miR-4652-3p	CLIP-seq
MIRT2510903	hsa-miR-4662a-3p	CLIP-seq
MIRT2510904	hsa-miR-4666-5p	CLIP-seq
MIRT1971950	hsa-miR-4719	CLIP-seq
MIRT2510906	hsa-miR-4760-3p	CLIP-seq
MIRT2510907	hsa-miR-4762-5p	CLIP-seq
MIRT916747	hsa-miR-4773	CLIP-seq
MIRT2510908	hsa-miR-4786-5p	CLIP-seq
MIRT2510909	hsa-miR-4803	CLIP-seq
MIRT2510910	hsa-miR-485-5p	CLIP-seq
MIRT1971956	hsa-miR-508-5p	CLIP-seq
MIRT1971957	hsa-miR-513b	CLIP-seq
MIRT2510911	hsa-miR-532-5p	CLIP-seq
MIRT2510912	hsa-miR-544b	CLIP-seq
MIRT2510913	hsa-miR-548aa	CLIP-seq
MIRT2510914	hsa-miR-548ac	CLIP-seq
MIRT2510916	hsa-miR-548d-3p	CLIP-seq
MIRT2510917	hsa-miR-548p	CLIP-seq
MIRT2510919	hsa-miR-548z	CLIP-seq
MIRT2510920	hsa-miR-589	CLIP-seq
MIRT2510921	hsa-miR-605	CLIP-seq
MIRT2510922	hsa-miR-641	CLIP-seq
MIRT2510923	hsa-miR-7	CLIP-seq
MIRT2510924	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	TAS	8681378
GO:0001837	Process	Epithelial to mesenchymal transition	IDA	16096638
GO:0004842	Function	Ubiquitin-protein transferase activity	TAS
GO:0005262	Function	Calcium channel activity	TAS	9581826
GO:0005515	Function	Protein binding	IPI	12504025, 16325183, 17500595, 18805092, 18826954, 19322197, 19933325, 21119685, 21145461, 21199876, 21516116, 21778237, 22190034, 24076655, 24402281, 25416956, 26906416, 28292928, 28514442, 29997244, 30833792, 31515488, 32296183, 32814053, 33961781, 35512830
GO:0005634	Component	Nucleus	IDA	38418882
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	NAS	26598620, 33999101, 35512830
GO:0005829	Component	Cytosol	TAS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0010498	Process	Proteasomal protein catabolic process	IEA
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IDA	29059170
GO:0016477	Process	Cell migration	IDA	35512830
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	NAS	35293963
GO:0019005	Component	SCF ubiquitin ligase complex	IBA
GO:0021819	Process	Layer formation in cerebral cortex	ISS
GO:0030335	Process	Positive regulation of cell migration	NAS	33999101, 35293963
GO:0030674	Function	Protein-macromolecule adaptor activity	IBA
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IDA	31387940
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	22017875, 22017876, 22017877
GO:0031461	Component	Cullin-RING ubiquitin ligase complex	IEA
GO:0031466	Component	Cul5-RING ubiquitin ligase complex	IBA
GO:0031466	Component	Cul5-RING ubiquitin ligase complex	IDA	17636018, 21980433, 22405651, 23897481, 25505247, 26598620, 31387940, 32513959, 33268465, 34518685, 35512830, 38418882, 38574733
GO:0031625	Function	Ubiquitin protein ligase binding	IBA
GO:0031625	Function	Ubiquitin protein ligase binding	IDA	17636018
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0038023	Function	Signaling receptor activity	TAS	9581826
GO:0038026	Process	Reelin-mediated signaling pathway	ISS
GO:0038128	Process	ERBB2 signaling pathway	TAS
GO:0038162	Process	Erythropoietin-mediated signaling pathway	IDA	2163696, 9657743
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	11781573, 21980433, 22190037, 27910872, 29059170, 31387940, 34518685, 35512830, 38418882, 38574733
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	21980433, 22190037, 26598620, 27910872, 31387940, 33268465, 34518685, 35512830, 38418882, 38574733
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	ISS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	NAS	38418882
GO:0045087	Process	Innate immune response	IDA	22915799
GO:0051607	Process	Defense response to virus	IDA	22915799
GO:0051894	Process	Positive regulation of focal adhesion assembly	IMP	35512830
GO:0051895	Process	Negative regulation of focal adhesion assembly	IDA	35512830
GO:0051895	Process	Negative regulation of focal adhesion assembly	IMP	35512830
GO:0052170	Process	Symbiont-mediated suppression of host innate immune response	IDA	22190037
GO:0060396	Process	Growth hormone receptor signaling pathway	IDA	2825030
GO:0060397	Process	Growth hormone receptor signaling pathway via JAK-STAT	IDA	12552091, 15690087
GO:0060400	Process	Negative regulation of growth hormone receptor signaling pathway	IDA	21980433
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	38418882
GO:0070979	Process	Protein K11-linked ubiquitination	IDA	27910872, 38574733
GO:0090734	Component	Site of DNA damage	IDA	28292928
GO:0097193	Process	Intrinsic apoptotic signaling pathway	TAS	9581826
GO:0120184	Process	Negative regulation of focal adhesion disassembly	IDA	26598620
GO:0140896	Process	CGAS/STING signaling pathway	IDA	30842659, 30842662, 32911482, 32912999
GO:0160049	Process	Negative regulation of cGAS/STING signaling pathway	IDA	38418882
GO:0160072	Function	Ubiquitin ligase complex scaffold activity	IDA	22190037, 23897481, 26598620, 27910872, 31387940, 33268465, 34518685, 35512830, 38574733
GO:2001222	Process	Regulation of neuron migration	ISS

Other IDs

• MIM: 601741
• HGNC: 2556
• e!Ensembl: ENSG00000166266

Protein

• UniProt ID: Q93034
• Protein name: Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
• Protein function: Core component of multiple cullin-5-RING E3 ubiquitin-protein ligase complexes (ECS complexes, also named CRL5 complexes), which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:11384984, PubMed:156018
• PDB: 3DPL, 3DQV, 4JGH, 4N9F, 6V9I, 7ONI, 8EI2, 8FVI, 8FVJ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00888	Cullin	19 → 672	Cullin family	Family
  PF10557	Cullin_Nedd8	710 → 772	Cullin protein neddylation domain	Domain

• Sequence:

  MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAK
  IHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMG
  KQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGV
  RESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKE
  EEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLM
  DKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQ
  DDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTP
  LSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWL
  REVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSS
  EKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQL
  AVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDF
  TEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAII
  QIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA
  

• Sequence length: 780

Pathways

KEGG:

Ubiquitin mediated proteolysis
Human immunodeficiency virus 1 infection

Reactome:

Vif-mediated degradation of APOBEC3G
Downregulation of ERBB2 signaling
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BREAST NEOPLASMS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LUMINAL A BREAST CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
RHEUMATOID ARTHRITIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TRIPLE-NEGATIVE BREAST CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Adenocarcinoma	Adenocarcinoma	BEFREE	26847831		★☆☆☆☆ Found in Text Mining only
Ataxia Telangiectasia	Ataxia Telangiectasia	BEFREE	15184056, 23977206		★☆☆☆☆ Found in Text Mining only
B-CELL MALIGNANCY, LOW-GRADE	Lymphocytic Leukemia	BEFREE	17449237		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	14641918, 15184056, 31374029		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	CTD_human_DG	20949323		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	14641918	Inhibit	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Breast neoplasm	Pubtator	26847831, 30999048, 31374029, 31759986, 35293963	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Carcinoma Endometrioid	Endometrioid carcinoma	Pubtator	26847831	Inhibit	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	24339204, 26512974	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma of lung	Lung carcinoma	BEFREE	27591266, 31294695		★☆☆☆☆ Found in Text Mining only
Chronic Lymphocytic Leukemia	Lymphocytic Leukemia	BEFREE	17449237		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	33712558, 37087475	Associate	★☆☆☆☆ Found in Text Mining only
Conventional (Clear Cell) Renal Cell Carcinoma	Renal Carcinoma	BEFREE	30631037		★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	BEFREE	15762197		★☆☆☆☆ Found in Text Mining only
Endometrial Neoplasms	Endometrial neoplasm	Pubtator	26847831	Associate	★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	35563538	Associate	★☆☆☆☆ Found in Text Mining only
Language Disorders	Language Disorders	BEFREE	23977206		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	24339204, 26512974		★☆☆☆☆ Found in Text Mining only
Lung Neoplasms	Lung neoplasms	Pubtator	31294695	Associate	★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	14641918, 15184056, 31374029		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	CTD_human_DG	20949323		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of liver	Liver Cancer	BEFREE	26847831		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of lung	Lung Cancer	BEFREE	27591266, 31294695		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	14641918, 21635549, 26847831		★☆☆☆☆ Found in Text Mining only
Mammary Carcinoma, Human	Marfan Syndrome	CTD_human_DG	20949323		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	14641918		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	CTD_human_DG	20949323		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms, Human	Mammary Neoplasms	CTD_human_DG	20949323		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	14641918, 24339204, 30631037		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	33099949	Inhibit	★☆☆☆☆ Found in Text Mining only
Pseudohypoaldosteronism	Pseudohypoparathyroidism	Pubtator	35563538	Associate	★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	30631037		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	GWASCAT_DG	30423114		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Small cell carcinoma of lung	Lung carcinoma	BEFREE	30688657		★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	34415831	Associate	★☆☆☆☆ Found in Text Mining only