TMEM254 (transmembrane protein 254)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID 80195
Gene name Transmembrane protein 254
Gene symbol TMEM254
Synonyms (NCBI Gene)
C10orf57bA369J21.6
Chromosome 10
Chromosome location 10q22.3
miRNA miRNA information provided by mirtarbase database.
51
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (51)
miRTarBase ID miRNA Experiments Reference
MIRT043526 hsa-miR-331-3p CLASH 23622248
MIRT560395 hsa-miR-3925-5p PAR-CLIP 20371350
MIRT560393 hsa-miR-3123 PAR-CLIP 20371350
MIRT560394 hsa-miR-4272 PAR-CLIP 20371350
MIRT560392 hsa-miR-4310 PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all (2)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TBM7
Protein name Transmembrane protein 254
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14934 DUF4499 24 → 113 Domain of unknown function (DUF4499) Family
Sequence
Sequence length 123
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (2)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CHRONIC OBSTRUCTIVE PULMONARY DISEASE — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Lung cancer Likely benign ClinVar
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (1)
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Chronic Obstructive Airway Disease Chronic Obstructive Pulmonary Disease GWASCAT_DG 23144326
★★★★★
★☆☆☆☆
Found in Text Mining only