Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	80071
Gene name	Coiled-coil domain containing 15
Gene symbol	CCDC15
Synonyms (NCBI Gene)	-
Chromosome	11
Chromosome location	11q24.2

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miRTarBase ID	miRNA	Experiments	Reference
MIRT024436	hsa-miR-215-5p	Microarray	19074876
MIRT026330	hsa-miR-192-5p	Microarray	19074876
MIRT029274	hsa-miR-26b-5p	Microarray	19088304
MIRT868423	hsa-miR-3125	CLIP-seq
MIRT868424	hsa-miR-3148	CLIP-seq
MIRT868425	hsa-miR-3916	CLIP-seq
MIRT868426	hsa-miR-4272	CLIP-seq
MIRT1957736	hsa-miR-1825	CLIP-seq
MIRT1957737	hsa-miR-199a-5p	CLIP-seq
MIRT1957738	hsa-miR-199b-5p	CLIP-seq
MIRT1957739	hsa-miR-2110	CLIP-seq
MIRT1957740	hsa-miR-3153	CLIP-seq
MIRT1957741	hsa-miR-4271	CLIP-seq
MIRT1957742	hsa-miR-4420	CLIP-seq
MIRT1957743	hsa-miR-4659a-3p	CLIP-seq
MIRT1957744	hsa-miR-4659b-3p	CLIP-seq
MIRT1957745	hsa-miR-4725-3p	CLIP-seq
MIRT1957746	hsa-miR-4790-3p	CLIP-seq
MIRT1957747	hsa-miR-583	CLIP-seq
MIRT1957748	hsa-miR-597	CLIP-seq
MIRT1957749	hsa-miR-668	CLIP-seq
MIRT1957736	hsa-miR-1825	CLIP-seq
MIRT1957737	hsa-miR-199a-5p	CLIP-seq
MIRT1957738	hsa-miR-199b-5p	CLIP-seq
MIRT1957739	hsa-miR-2110	CLIP-seq
MIRT1957740	hsa-miR-3153	CLIP-seq
MIRT1957741	hsa-miR-4271	CLIP-seq
MIRT1957742	hsa-miR-4420	CLIP-seq
MIRT1957745	hsa-miR-4725-3p	CLIP-seq
MIRT1957746	hsa-miR-4790-3p	CLIP-seq
MIRT1957747	hsa-miR-583	CLIP-seq
MIRT1957748	hsa-miR-597	CLIP-seq
MIRT1957749	hsa-miR-668	CLIP-seq
MIRT2446405	hsa-miR-216a	CLIP-seq
MIRT2446406	hsa-miR-23a	CLIP-seq
MIRT2446407	hsa-miR-23b	CLIP-seq
MIRT2446408	hsa-miR-23c	CLIP-seq
MIRT2446409	hsa-miR-3123	CLIP-seq
MIRT2446410	hsa-miR-371-5p	CLIP-seq
MIRT2446411	hsa-miR-371b-5p	CLIP-seq
MIRT2446412	hsa-miR-4717-3p	CLIP-seq
MIRT2446413	hsa-miR-548u	CLIP-seq
MIRT2446405	hsa-miR-216a	CLIP-seq
MIRT2446406	hsa-miR-23a	CLIP-seq
MIRT2446407	hsa-miR-23b	CLIP-seq
MIRT2446408	hsa-miR-23c	CLIP-seq
MIRT2446409	hsa-miR-3123	CLIP-seq
MIRT2446410	hsa-miR-371-5p	CLIP-seq
MIRT2446411	hsa-miR-371b-5p	CLIP-seq
MIRT2446412	hsa-miR-4717-3p	CLIP-seq
MIRT2446413	hsa-miR-548u	CLIP-seq
MIRT2446405	hsa-miR-216a	CLIP-seq
MIRT2446406	hsa-miR-23a	CLIP-seq
MIRT2446407	hsa-miR-23b	CLIP-seq
MIRT2446408	hsa-miR-23c	CLIP-seq
MIRT2446409	hsa-miR-3123	CLIP-seq
MIRT2446410	hsa-miR-371-5p	CLIP-seq
MIRT2446411	hsa-miR-371b-5p	CLIP-seq
MIRT2446412	hsa-miR-4717-3p	CLIP-seq
MIRT2446413	hsa-miR-548u	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IBA
GO:0005813	Component	Centrosome	IDA	21399614, 37934472
GO:0005813	Component	Centrosome	IEA
GO:0005814	Component	Centriole	IDA	37934472
GO:0005814	Component	Centriole	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0030030	Process	Cell projection organization	IEA
GO:0034451	Component	Centriolar satellite	IEA
GO:0060271	Process	Cilium assembly	IMP	37934472
GO:1903724	Process	Positive regulation of centriole elongation	IMP	37934472

MIM	HGNC	e!Ensembl
621146	25798	ENSG00000149548

Q0P6D6

Protein name

Coiled-coil domain-containing protein 15

Protein function

Plays an important role in primary cilium assembly, maintenance, and length regulation. Interacts with centriole inner scaffold proteins to promote proper centriole size and integrity and assembly of functional cilia. Required for the recruitmen

Family and domains

Sequence

MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYT
SAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQS
SATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQA
RHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLA
AVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQ
KVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT
QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL
TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFL
SRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFL
SRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNIL
PICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLAD
YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP
SSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRL
FMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILA
QLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTC
ANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL

Sequence length

951

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
BLADDER EXSTROPHY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
COLORECTAL CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Neurodevelopmental disorder	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEURODEVELOPMENTAL DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

CCDC15 (coiled-coil domain containing 15)