Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	80063
Gene name	Activating transcription factor 7 interacting protein 2
Gene symbol	ATF7IP2
Synonyms (NCBI Gene)	MCAF2
Chromosome	16
Chromosome location	16p13.2-p13.13

139

Show/Hide all (139)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025051	hsa-miR-181a-5p	Microarray	17612493
MIRT025761	hsa-miR-7-5p	Microarray	17612493
MIRT609962	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT609961	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT282757	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT609960	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT609959	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT609958	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT609957	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT609956	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT609955	hsa-miR-4775	HITS-CLIP	23824327
MIRT609962	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT609961	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT282757	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT609960	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT609959	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT609958	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT609957	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT609956	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT609955	hsa-miR-4775	HITS-CLIP	23824327
MIRT804667	hsa-miR-105	CLIP-seq
MIRT804668	hsa-miR-1229	CLIP-seq
MIRT804669	hsa-miR-125a-5p	CLIP-seq
MIRT804670	hsa-miR-125b	CLIP-seq
MIRT804671	hsa-miR-1273e	CLIP-seq
MIRT804672	hsa-miR-1273f	CLIP-seq
MIRT804673	hsa-miR-1291	CLIP-seq
MIRT804674	hsa-miR-140-3p	CLIP-seq
MIRT804675	hsa-miR-186	CLIP-seq
MIRT804676	hsa-miR-214	CLIP-seq
MIRT804677	hsa-miR-2681	CLIP-seq
MIRT804678	hsa-miR-2964a-3p	CLIP-seq
MIRT804679	hsa-miR-302f	CLIP-seq
MIRT804680	hsa-miR-3074-5p	CLIP-seq
MIRT804681	hsa-miR-3126-3p	CLIP-seq
MIRT804682	hsa-miR-3137	CLIP-seq
MIRT804683	hsa-miR-3138	CLIP-seq
MIRT804684	hsa-miR-3165	CLIP-seq
MIRT804685	hsa-miR-3176	CLIP-seq
MIRT804686	hsa-miR-328	CLIP-seq
MIRT804687	hsa-miR-331-3p	CLIP-seq
MIRT804688	hsa-miR-3619-5p	CLIP-seq
MIRT804689	hsa-miR-3622b-5p	CLIP-seq
MIRT804690	hsa-miR-3656	CLIP-seq
MIRT804691	hsa-miR-3672	CLIP-seq
MIRT804692	hsa-miR-374a	CLIP-seq
MIRT804693	hsa-miR-374b	CLIP-seq
MIRT804694	hsa-miR-3922-3p	CLIP-seq
MIRT804695	hsa-miR-4264	CLIP-seq
MIRT804696	hsa-miR-4270	CLIP-seq
MIRT804697	hsa-miR-4293	CLIP-seq
MIRT804698	hsa-miR-4307	CLIP-seq
MIRT804699	hsa-miR-4319	CLIP-seq
MIRT804700	hsa-miR-4433	CLIP-seq
MIRT804701	hsa-miR-4441	CLIP-seq
MIRT804702	hsa-miR-4446-3p	CLIP-seq
MIRT804703	hsa-miR-4459	CLIP-seq
MIRT804704	hsa-miR-4496	CLIP-seq
MIRT804705	hsa-miR-4645-5p	CLIP-seq
MIRT804706	hsa-miR-4656	CLIP-seq
MIRT804707	hsa-miR-4673	CLIP-seq
MIRT804708	hsa-miR-4704-3p	CLIP-seq
MIRT804709	hsa-miR-4728-3p	CLIP-seq
MIRT804710	hsa-miR-4755-3p	CLIP-seq
MIRT804711	hsa-miR-4761-5p	CLIP-seq
MIRT804712	hsa-miR-4762-5p	CLIP-seq
MIRT804713	hsa-miR-4768-3p	CLIP-seq
MIRT804714	hsa-miR-4786-5p	CLIP-seq
MIRT804715	hsa-miR-486-5p	CLIP-seq
MIRT804716	hsa-miR-544b	CLIP-seq
MIRT804717	hsa-miR-545	CLIP-seq
MIRT804718	hsa-miR-567	CLIP-seq
MIRT804719	hsa-miR-624	CLIP-seq
MIRT804720	hsa-miR-628-5p	CLIP-seq
MIRT804721	hsa-miR-651	CLIP-seq
MIRT804722	hsa-miR-761	CLIP-seq
MIRT804723	hsa-miR-769-5p	CLIP-seq
MIRT1937550	hsa-miR-1285	CLIP-seq
MIRT1937551	hsa-miR-1587	CLIP-seq
MIRT1937552	hsa-miR-3145-5p	CLIP-seq
MIRT804685	hsa-miR-3176	CLIP-seq
MIRT1937553	hsa-miR-3187-5p	CLIP-seq
MIRT804694	hsa-miR-3922-3p	CLIP-seq
MIRT1937554	hsa-miR-4492	CLIP-seq
MIRT1937555	hsa-miR-4498	CLIP-seq
MIRT804706	hsa-miR-4656	CLIP-seq
MIRT1937556	hsa-miR-4674	CLIP-seq
MIRT1937557	hsa-miR-4675	CLIP-seq
MIRT1937558	hsa-miR-4741	CLIP-seq
MIRT1937559	hsa-miR-508-5p	CLIP-seq
MIRT1937560	hsa-miR-578	CLIP-seq
MIRT1937561	hsa-miR-612	CLIP-seq
MIRT1937562	hsa-miR-635	CLIP-seq
MIRT1937563	hsa-miR-661	CLIP-seq
MIRT1937564	hsa-miR-762	CLIP-seq
MIRT1937565	hsa-miR-766	CLIP-seq
MIRT1937550	hsa-miR-1285	CLIP-seq
MIRT1937552	hsa-miR-3145-5p	CLIP-seq
MIRT1937553	hsa-miR-3187-5p	CLIP-seq
MIRT2177183	hsa-miR-3942-5p	CLIP-seq
MIRT804697	hsa-miR-4293	CLIP-seq
MIRT2177184	hsa-miR-4703-5p	CLIP-seq
MIRT1937559	hsa-miR-508-5p	CLIP-seq
MIRT1937561	hsa-miR-612	CLIP-seq
MIRT1937563	hsa-miR-661	CLIP-seq
MIRT1937565	hsa-miR-766	CLIP-seq
MIRT804668	hsa-miR-1229	CLIP-seq
MIRT2444162	hsa-miR-4680-5p	CLIP-seq
MIRT804668	hsa-miR-1229	CLIP-seq
MIRT2444162	hsa-miR-4680-5p	CLIP-seq
MIRT804668	hsa-miR-1229	CLIP-seq
MIRT804671	hsa-miR-1273e	CLIP-seq
MIRT804672	hsa-miR-1273f	CLIP-seq
MIRT1937550	hsa-miR-1285	CLIP-seq
MIRT804678	hsa-miR-2964a-3p	CLIP-seq
MIRT804679	hsa-miR-302f	CLIP-seq
MIRT1937552	hsa-miR-3145-5p	CLIP-seq
MIRT1937553	hsa-miR-3187-5p	CLIP-seq
MIRT2177183	hsa-miR-3942-5p	CLIP-seq
MIRT804696	hsa-miR-4270	CLIP-seq
MIRT804701	hsa-miR-4441	CLIP-seq
MIRT2444162	hsa-miR-4680-5p	CLIP-seq
MIRT2177184	hsa-miR-4703-5p	CLIP-seq
MIRT1937559	hsa-miR-508-5p	CLIP-seq
MIRT1937561	hsa-miR-612	CLIP-seq
MIRT1937563	hsa-miR-661	CLIP-seq
MIRT1937565	hsa-miR-766	CLIP-seq
MIRT804668	hsa-miR-1229	CLIP-seq
MIRT1937550	hsa-miR-1285	CLIP-seq
MIRT1937552	hsa-miR-3145-5p	CLIP-seq
MIRT1937553	hsa-miR-3187-5p	CLIP-seq
MIRT2675577	hsa-miR-371-5p	CLIP-seq
MIRT2177183	hsa-miR-3942-5p	CLIP-seq
MIRT2444162	hsa-miR-4680-5p	CLIP-seq
MIRT2177184	hsa-miR-4703-5p	CLIP-seq
MIRT1937559	hsa-miR-508-5p	CLIP-seq
MIRT1937561	hsa-miR-612	CLIP-seq
MIRT1937563	hsa-miR-661	CLIP-seq
MIRT1937565	hsa-miR-766	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005667	Component	Transcription regulator complex	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA

MIM	HGNC	e!Ensembl
613645	20397	ENSG00000166669

Q5U623

Protein name

Activating transcription factor 7-interacting protein 2 (ATF7-interacting protein 2) (MBD1-containing chromatin-associated factor 2)

Protein function

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-depende

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16788	ATF7IP_BD	291 → 499	ATF-interacting protein binding domain	Family
PF16794	fn3_4	574 → 673	Fibronectin-III type domain	Domain

Sequence

MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITR
TTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPS
RTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQM
PESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVT
SNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTS
EQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGI
ADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEK
SSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKI
TSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLA
QNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITK
INPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKD
IFGRYGPFCDIKSIPGFSENLT

Sequence length

682

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (8)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
EYE DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VASCULAR DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
WET MACULAR DEGENERATION	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Choroidal Neovascularization	Choroidal neovascularization	Pubtator	29346644	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Geographic Atrophy	Geographic Atrophy	BEFREE	29346644		★★★★★ ★☆☆☆☆ Found in Text Mining only

ATF7IP2 (activating transcription factor 7 interacting protein 2)