DOCK5 (dedicator of cytokinesis 5)

Gene

• Entrez ID: 80005
• Gene name: Dedicator of cytokinesis 5
• Gene symbol: DOCK5
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8p21.2
• Summary: This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family act as guanine nucleotide exchange factors for small Rho family G proteins. The protein encoded by this gene is thought to associate with adaptors CRK and CR

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT001638	hsa-let-7b-5p	pSILAC	18668040
MIRT006314	hsa-miR-21-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22158624
MIRT006314	hsa-miR-21-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22158624
MIRT006314	hsa-miR-21-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22158624
MIRT025783	hsa-miR-7-5p	Microarray	17612493
MIRT027646	hsa-miR-98-5p	Microarray	19088304
MIRT031712	hsa-miR-16-5p	Proteomics	18668040
MIRT001638	hsa-let-7b-5p	Proteomics;Other	18668040
MIRT046721	hsa-miR-222-3p	CLASH	23622248
MIRT038767	hsa-miR-93-3p	CLASH	23622248
MIRT036937	hsa-miR-877-3p	CLASH	23622248
MIRT658950	hsa-miR-513b-3p	HITS-CLIP	23824327
MIRT658948	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT658949	hsa-miR-4719	HITS-CLIP	23824327
MIRT658950	hsa-miR-513b-3p	HITS-CLIP	23824327
MIRT658948	hsa-miR-4762-5p	HITS-CLIP	23824327
MIRT658949	hsa-miR-4719	HITS-CLIP	23824327
MIRT942889	hsa-miR-1	CLIP-seq
MIRT942890	hsa-miR-1197	CLIP-seq
MIRT942891	hsa-miR-122	CLIP-seq
MIRT942892	hsa-miR-1224-5p	CLIP-seq
MIRT942893	hsa-miR-1225-3p	CLIP-seq
MIRT942894	hsa-miR-1236	CLIP-seq
MIRT942895	hsa-miR-1269	CLIP-seq
MIRT942896	hsa-miR-1269b	CLIP-seq
MIRT942897	hsa-miR-1288	CLIP-seq
MIRT942898	hsa-miR-1299	CLIP-seq
MIRT942899	hsa-miR-1321	CLIP-seq
MIRT942900	hsa-miR-134	CLIP-seq
MIRT942901	hsa-miR-1587	CLIP-seq
MIRT942902	hsa-miR-19a	CLIP-seq
MIRT942903	hsa-miR-19b	CLIP-seq
MIRT942904	hsa-miR-206	CLIP-seq
MIRT942905	hsa-miR-214	CLIP-seq
MIRT942906	hsa-miR-25	CLIP-seq
MIRT942907	hsa-miR-30a	CLIP-seq
MIRT942908	hsa-miR-30b	CLIP-seq
MIRT942909	hsa-miR-30c	CLIP-seq
MIRT942910	hsa-miR-30d	CLIP-seq
MIRT942911	hsa-miR-30e	CLIP-seq
MIRT942912	hsa-miR-3118	CLIP-seq
MIRT942913	hsa-miR-3135b	CLIP-seq
MIRT942914	hsa-miR-3136-5p	CLIP-seq
MIRT942915	hsa-miR-3138	CLIP-seq
MIRT942916	hsa-miR-3140-3p	CLIP-seq
MIRT942917	hsa-miR-3163	CLIP-seq
MIRT942918	hsa-miR-3164	CLIP-seq
MIRT942919	hsa-miR-3182	CLIP-seq
MIRT942920	hsa-miR-3189-5p	CLIP-seq
MIRT942921	hsa-miR-32	CLIP-seq
MIRT942922	hsa-miR-3202	CLIP-seq
MIRT942923	hsa-miR-3607-5p	CLIP-seq
MIRT942924	hsa-miR-3612	CLIP-seq
MIRT942925	hsa-miR-3616-3p	CLIP-seq
MIRT942926	hsa-miR-3619-5p	CLIP-seq
MIRT942927	hsa-miR-3622b-5p	CLIP-seq
MIRT942928	hsa-miR-363	CLIP-seq
MIRT942929	hsa-miR-3652	CLIP-seq
MIRT942930	hsa-miR-3657	CLIP-seq
MIRT942931	hsa-miR-367	CLIP-seq
MIRT942932	hsa-miR-3673	CLIP-seq
MIRT942933	hsa-miR-3689d	CLIP-seq
MIRT942934	hsa-miR-371b-5p	CLIP-seq
MIRT942935	hsa-miR-3923	CLIP-seq
MIRT942936	hsa-miR-3925-3p	CLIP-seq
MIRT942937	hsa-miR-4257	CLIP-seq
MIRT942938	hsa-miR-4270	CLIP-seq
MIRT942939	hsa-miR-4277	CLIP-seq
MIRT942940	hsa-miR-4291	CLIP-seq
MIRT942941	hsa-miR-4302	CLIP-seq
MIRT942942	hsa-miR-4311	CLIP-seq
MIRT942943	hsa-miR-4323	CLIP-seq
MIRT942944	hsa-miR-4325	CLIP-seq
MIRT942945	hsa-miR-4419a	CLIP-seq
MIRT942946	hsa-miR-4430	CLIP-seq
MIRT942947	hsa-miR-4433	CLIP-seq
MIRT942948	hsa-miR-4436b-3p	CLIP-seq
MIRT942949	hsa-miR-4439	CLIP-seq
MIRT942950	hsa-miR-4441	CLIP-seq
MIRT942951	hsa-miR-4443	CLIP-seq
MIRT942952	hsa-miR-4459	CLIP-seq
MIRT942953	hsa-miR-4474-3p	CLIP-seq
MIRT942954	hsa-miR-4490	CLIP-seq
MIRT942955	hsa-miR-4491	CLIP-seq
MIRT942956	hsa-miR-4492	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT942958	hsa-miR-4498	CLIP-seq
MIRT942959	hsa-miR-4506	CLIP-seq
MIRT942960	hsa-miR-450b-3p	CLIP-seq
MIRT942961	hsa-miR-4510	CLIP-seq
MIRT942962	hsa-miR-4513	CLIP-seq
MIRT942963	hsa-miR-4515	CLIP-seq
MIRT942964	hsa-miR-451b	CLIP-seq
MIRT942965	hsa-miR-4533	CLIP-seq
MIRT942966	hsa-miR-455-5p	CLIP-seq
MIRT942967	hsa-miR-4656	CLIP-seq
MIRT942968	hsa-miR-4657	CLIP-seq
MIRT942969	hsa-miR-4659a-3p	CLIP-seq
MIRT942970	hsa-miR-4659b-3p	CLIP-seq
MIRT942971	hsa-miR-4668-3p	CLIP-seq
MIRT942972	hsa-miR-4669	CLIP-seq
MIRT942973	hsa-miR-4674	CLIP-seq
MIRT942974	hsa-miR-4675	CLIP-seq
MIRT942975	hsa-miR-4698	CLIP-seq
MIRT942976	hsa-miR-4713-3p	CLIP-seq
MIRT942977	hsa-miR-4716-5p	CLIP-seq
MIRT942978	hsa-miR-4739	CLIP-seq
MIRT942979	hsa-miR-4740-5p	CLIP-seq
MIRT942980	hsa-miR-4741	CLIP-seq
MIRT942981	hsa-miR-4742-3p	CLIP-seq
MIRT942982	hsa-miR-4751	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942984	hsa-miR-4756-5p	CLIP-seq
MIRT942985	hsa-miR-4757-5p	CLIP-seq
MIRT942986	hsa-miR-4766-3p	CLIP-seq
MIRT942987	hsa-miR-4766-5p	CLIP-seq
MIRT942988	hsa-miR-4768-3p	CLIP-seq
MIRT942989	hsa-miR-4772-5p	CLIP-seq
MIRT942990	hsa-miR-4782-5p	CLIP-seq
MIRT942991	hsa-miR-4800-5p	CLIP-seq
MIRT942992	hsa-miR-488	CLIP-seq
MIRT942993	hsa-miR-515-5p	CLIP-seq
MIRT942994	hsa-miR-516b	CLIP-seq
MIRT942995	hsa-miR-539	CLIP-seq
MIRT942996	hsa-miR-541	CLIP-seq
MIRT942997	hsa-miR-548a-3p	CLIP-seq
MIRT942998	hsa-miR-548e	CLIP-seq
MIRT942999	hsa-miR-548f	CLIP-seq
MIRT943000	hsa-miR-574-5p	CLIP-seq
MIRT943001	hsa-miR-613	CLIP-seq
MIRT943002	hsa-miR-629	CLIP-seq
MIRT943003	hsa-miR-630	CLIP-seq
MIRT943004	hsa-miR-638	CLIP-seq
MIRT943005	hsa-miR-650	CLIP-seq
MIRT943006	hsa-miR-654-5p	CLIP-seq
MIRT943007	hsa-miR-665	CLIP-seq
MIRT943008	hsa-miR-7	CLIP-seq
MIRT943009	hsa-miR-761	CLIP-seq
MIRT943010	hsa-miR-762	CLIP-seq
MIRT943011	hsa-miR-766	CLIP-seq
MIRT943012	hsa-miR-769-3p	CLIP-seq
MIRT943013	hsa-miR-873	CLIP-seq
MIRT943014	hsa-miR-875-3p	CLIP-seq
MIRT943015	hsa-miR-922	CLIP-seq
MIRT943016	hsa-miR-92a	CLIP-seq
MIRT943017	hsa-miR-92b	CLIP-seq
MIRT1979200	hsa-miR-124	CLIP-seq
MIRT1979201	hsa-miR-1262	CLIP-seq
MIRT1979202	hsa-miR-1266	CLIP-seq
MIRT1979203	hsa-miR-1293	CLIP-seq
MIRT1979204	hsa-miR-136	CLIP-seq
MIRT1979205	hsa-miR-1914	CLIP-seq
MIRT942906	hsa-miR-25	CLIP-seq
MIRT1979206	hsa-miR-3124-3p	CLIP-seq
MIRT1979207	hsa-miR-3127-5p	CLIP-seq
MIRT942917	hsa-miR-3163	CLIP-seq
MIRT942921	hsa-miR-32	CLIP-seq
MIRT942927	hsa-miR-3622b-5p	CLIP-seq
MIRT942928	hsa-miR-363	CLIP-seq
MIRT942931	hsa-miR-367	CLIP-seq
MIRT942934	hsa-miR-371b-5p	CLIP-seq
MIRT1979208	hsa-miR-3918	CLIP-seq
MIRT1979209	hsa-miR-4259	CLIP-seq
MIRT1979210	hsa-miR-4269	CLIP-seq
MIRT942942	hsa-miR-4311	CLIP-seq
MIRT942944	hsa-miR-4325	CLIP-seq
MIRT1979211	hsa-miR-4446-3p	CLIP-seq
MIRT1979212	hsa-miR-4483	CLIP-seq
MIRT1979213	hsa-miR-4511	CLIP-seq
MIRT942963	hsa-miR-4515	CLIP-seq
MIRT1979214	hsa-miR-4518	CLIP-seq
MIRT942964	hsa-miR-451b	CLIP-seq
MIRT942967	hsa-miR-4656	CLIP-seq
MIRT942971	hsa-miR-4668-3p	CLIP-seq
MIRT942975	hsa-miR-4698	CLIP-seq
MIRT1979215	hsa-miR-4701-3p	CLIP-seq
MIRT942981	hsa-miR-4742-3p	CLIP-seq
MIRT1979216	hsa-miR-4742-5p	CLIP-seq
MIRT942985	hsa-miR-4757-5p	CLIP-seq
MIRT942986	hsa-miR-4766-3p	CLIP-seq
MIRT942989	hsa-miR-4772-5p	CLIP-seq
MIRT1979217	hsa-miR-506	CLIP-seq
MIRT1979218	hsa-miR-510	CLIP-seq
MIRT942995	hsa-miR-539	CLIP-seq
MIRT1979219	hsa-miR-571	CLIP-seq
MIRT943003	hsa-miR-630	CLIP-seq
MIRT943013	hsa-miR-873	CLIP-seq
MIRT943016	hsa-miR-92a	CLIP-seq
MIRT943017	hsa-miR-92b	CLIP-seq
MIRT942894	hsa-miR-1236	CLIP-seq
MIRT942900	hsa-miR-134	CLIP-seq
MIRT1979204	hsa-miR-136	CLIP-seq
MIRT2214318	hsa-miR-2114	CLIP-seq
MIRT942912	hsa-miR-3118	CLIP-seq
MIRT2214319	hsa-miR-3123	CLIP-seq
MIRT2214320	hsa-miR-3128	CLIP-seq
MIRT942923	hsa-miR-3607-5p	CLIP-seq
MIRT2214321	hsa-miR-3924	CLIP-seq
MIRT2214322	hsa-miR-4261	CLIP-seq
MIRT2214323	hsa-miR-4267	CLIP-seq
MIRT1979210	hsa-miR-4269	CLIP-seq
MIRT942938	hsa-miR-4270	CLIP-seq
MIRT942950	hsa-miR-4441	CLIP-seq
MIRT2214324	hsa-miR-4463	CLIP-seq
MIRT942953	hsa-miR-4474-3p	CLIP-seq
MIRT942954	hsa-miR-4490	CLIP-seq
MIRT2214325	hsa-miR-4494	CLIP-seq
MIRT2214326	hsa-miR-4514	CLIP-seq
MIRT942971	hsa-miR-4668-3p	CLIP-seq
MIRT2214327	hsa-miR-4692	CLIP-seq
MIRT2214328	hsa-miR-4720-5p	CLIP-seq
MIRT1979216	hsa-miR-4742-5p	CLIP-seq
MIRT2214329	hsa-miR-4777-5p	CLIP-seq
MIRT2214330	hsa-miR-4799-3p	CLIP-seq
MIRT2214331	hsa-miR-511	CLIP-seq
MIRT2214332	hsa-miR-518d-5p	CLIP-seq
MIRT2214333	hsa-miR-519b-5p	CLIP-seq
MIRT2214334	hsa-miR-519c-5p	CLIP-seq
MIRT2214335	hsa-miR-520c-5p	CLIP-seq
MIRT2214336	hsa-miR-526a	CLIP-seq
MIRT942997	hsa-miR-548a-3p	CLIP-seq
MIRT942998	hsa-miR-548e	CLIP-seq
MIRT942999	hsa-miR-548f	CLIP-seq
MIRT2214337	hsa-miR-634	CLIP-seq
MIRT2214338	hsa-miR-885-3p	CLIP-seq
MIRT943015	hsa-miR-922	CLIP-seq
MIRT2214339	hsa-miR-940	CLIP-seq
MIRT942895	hsa-miR-1269	CLIP-seq
MIRT942896	hsa-miR-1269b	CLIP-seq
MIRT942897	hsa-miR-1288	CLIP-seq
MIRT942899	hsa-miR-1321	CLIP-seq
MIRT942915	hsa-miR-3138	CLIP-seq
MIRT942922	hsa-miR-3202	CLIP-seq
MIRT942927	hsa-miR-3622b-5p	CLIP-seq
MIRT942933	hsa-miR-3689d	CLIP-seq
MIRT942934	hsa-miR-371b-5p	CLIP-seq
MIRT942955	hsa-miR-4491	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT942963	hsa-miR-4515	CLIP-seq
MIRT942965	hsa-miR-4533	CLIP-seq
MIRT942968	hsa-miR-4657	CLIP-seq
MIRT942975	hsa-miR-4698	CLIP-seq
MIRT942977	hsa-miR-4716-5p	CLIP-seq
MIRT942978	hsa-miR-4739	CLIP-seq
MIRT942979	hsa-miR-4740-5p	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942984	hsa-miR-4756-5p	CLIP-seq
MIRT942985	hsa-miR-4757-5p	CLIP-seq
MIRT942991	hsa-miR-4800-5p	CLIP-seq
MIRT2387070	hsa-miR-582-3p	CLIP-seq
MIRT942889	hsa-miR-1	CLIP-seq
MIRT942890	hsa-miR-1197	CLIP-seq
MIRT942891	hsa-miR-122	CLIP-seq
MIRT942892	hsa-miR-1224-5p	CLIP-seq
MIRT942893	hsa-miR-1225-3p	CLIP-seq
MIRT942894	hsa-miR-1236	CLIP-seq
MIRT1979200	hsa-miR-124	CLIP-seq
MIRT1979202	hsa-miR-1266	CLIP-seq
MIRT942904	hsa-miR-206	CLIP-seq
MIRT942905	hsa-miR-214	CLIP-seq
MIRT2436867	hsa-miR-216b	CLIP-seq
MIRT942913	hsa-miR-3135b	CLIP-seq
MIRT942920	hsa-miR-3189-5p	CLIP-seq
MIRT942924	hsa-miR-3612	CLIP-seq
MIRT942926	hsa-miR-3619-5p	CLIP-seq
MIRT942929	hsa-miR-3652	CLIP-seq
MIRT2436868	hsa-miR-3664-3p	CLIP-seq
MIRT942932	hsa-miR-3673	CLIP-seq
MIRT2436869	hsa-miR-3714	CLIP-seq
MIRT2436870	hsa-miR-3910	CLIP-seq
MIRT2436871	hsa-miR-3978	CLIP-seq
MIRT1979210	hsa-miR-4269	CLIP-seq
MIRT942938	hsa-miR-4270	CLIP-seq
MIRT942939	hsa-miR-4277	CLIP-seq
MIRT942940	hsa-miR-4291	CLIP-seq
MIRT942943	hsa-miR-4323	CLIP-seq
MIRT942946	hsa-miR-4430	CLIP-seq
MIRT942947	hsa-miR-4433	CLIP-seq
MIRT942950	hsa-miR-4441	CLIP-seq
MIRT942951	hsa-miR-4443	CLIP-seq
MIRT942952	hsa-miR-4459	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT2214326	hsa-miR-4514	CLIP-seq
MIRT1979214	hsa-miR-4518	CLIP-seq
MIRT2436872	hsa-miR-4521	CLIP-seq
MIRT2214327	hsa-miR-4692	CLIP-seq
MIRT1979216	hsa-miR-4742-5p	CLIP-seq
MIRT942982	hsa-miR-4751	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942987	hsa-miR-4766-5p	CLIP-seq
MIRT942988	hsa-miR-4768-3p	CLIP-seq
MIRT942989	hsa-miR-4772-5p	CLIP-seq
MIRT1979217	hsa-miR-506	CLIP-seq
MIRT943001	hsa-miR-613	CLIP-seq
MIRT2436873	hsa-miR-626	CLIP-seq
MIRT2436874	hsa-miR-646	CLIP-seq
MIRT943005	hsa-miR-650	CLIP-seq
MIRT943009	hsa-miR-761	CLIP-seq
MIRT943013	hsa-miR-873	CLIP-seq
MIRT943015	hsa-miR-922	CLIP-seq
MIRT942891	hsa-miR-122	CLIP-seq
MIRT942947	hsa-miR-4433	CLIP-seq
MIRT942952	hsa-miR-4459	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942988	hsa-miR-4768-3p	CLIP-seq
MIRT943000	hsa-miR-574-5p	CLIP-seq
MIRT942891	hsa-miR-122	CLIP-seq
MIRT2518641	hsa-miR-1227	CLIP-seq
MIRT942894	hsa-miR-1236	CLIP-seq
MIRT942895	hsa-miR-1269	CLIP-seq
MIRT942896	hsa-miR-1269b	CLIP-seq
MIRT2518642	hsa-miR-1272	CLIP-seq
MIRT942897	hsa-miR-1288	CLIP-seq
MIRT1979203	hsa-miR-1293	CLIP-seq
MIRT942898	hsa-miR-1299	CLIP-seq
MIRT942899	hsa-miR-1321	CLIP-seq
MIRT2518643	hsa-miR-1343	CLIP-seq
MIRT1979205	hsa-miR-1914	CLIP-seq
MIRT2518644	hsa-miR-1976	CLIP-seq
MIRT2518645	hsa-miR-2117	CLIP-seq
MIRT2436867	hsa-miR-216b	CLIP-seq
MIRT2518646	hsa-miR-3064-3p	CLIP-seq
MIRT2518647	hsa-miR-3074-5p	CLIP-seq
MIRT2214319	hsa-miR-3123	CLIP-seq
MIRT1979206	hsa-miR-3124-3p	CLIP-seq
MIRT2214320	hsa-miR-3128	CLIP-seq
MIRT942915	hsa-miR-3138	CLIP-seq
MIRT942916	hsa-miR-3140-3p	CLIP-seq
MIRT2518648	hsa-miR-3140-5p	CLIP-seq
MIRT2518649	hsa-miR-3146	CLIP-seq
MIRT2518650	hsa-miR-3168	CLIP-seq
MIRT942922	hsa-miR-3202	CLIP-seq
MIRT2518651	hsa-miR-3545-3p	CLIP-seq
MIRT942925	hsa-miR-3616-3p	CLIP-seq
MIRT942927	hsa-miR-3622b-5p	CLIP-seq
MIRT2518652	hsa-miR-3665	CLIP-seq
MIRT2518653	hsa-miR-3681	CLIP-seq
MIRT2518654	hsa-miR-3688-3p	CLIP-seq
MIRT942933	hsa-miR-3689d	CLIP-seq
MIRT942934	hsa-miR-371b-5p	CLIP-seq
MIRT2518655	hsa-miR-3919	CLIP-seq
MIRT2436871	hsa-miR-3978	CLIP-seq
MIRT2518656	hsa-miR-412	CLIP-seq
MIRT2214322	hsa-miR-4261	CLIP-seq
MIRT2214323	hsa-miR-4267	CLIP-seq
MIRT1979210	hsa-miR-4269	CLIP-seq
MIRT2518657	hsa-miR-4273	CLIP-seq
MIRT942942	hsa-miR-4311	CLIP-seq
MIRT2518658	hsa-miR-433	CLIP-seq
MIRT942945	hsa-miR-4419a	CLIP-seq
MIRT2518659	hsa-miR-4426	CLIP-seq
MIRT942947	hsa-miR-4433	CLIP-seq
MIRT942948	hsa-miR-4436b-3p	CLIP-seq
MIRT2518660	hsa-miR-4447	CLIP-seq
MIRT942952	hsa-miR-4459	CLIP-seq
MIRT2518661	hsa-miR-4460	CLIP-seq
MIRT2518662	hsa-miR-4472	CLIP-seq
MIRT1979212	hsa-miR-4483	CLIP-seq
MIRT942955	hsa-miR-4491	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT2518663	hsa-miR-4496	CLIP-seq
MIRT942959	hsa-miR-4506	CLIP-seq
MIRT942961	hsa-miR-4510	CLIP-seq
MIRT2214326	hsa-miR-4514	CLIP-seq
MIRT942963	hsa-miR-4515	CLIP-seq
MIRT942965	hsa-miR-4533	CLIP-seq
MIRT2518664	hsa-miR-4641	CLIP-seq
MIRT2518665	hsa-miR-4647	CLIP-seq
MIRT942968	hsa-miR-4657	CLIP-seq
MIRT2518666	hsa-miR-4662b	CLIP-seq
MIRT2214327	hsa-miR-4692	CLIP-seq
MIRT2518667	hsa-miR-4694-3p	CLIP-seq
MIRT942975	hsa-miR-4698	CLIP-seq
MIRT2518668	hsa-miR-4703-3p	CLIP-seq
MIRT942977	hsa-miR-4716-5p	CLIP-seq
MIRT2214328	hsa-miR-4720-5p	CLIP-seq
MIRT2518669	hsa-miR-4725-5p	CLIP-seq
MIRT2518670	hsa-miR-4727-3p	CLIP-seq
MIRT942978	hsa-miR-4739	CLIP-seq
MIRT942979	hsa-miR-4740-5p	CLIP-seq
MIRT1979216	hsa-miR-4742-5p	CLIP-seq
MIRT2518671	hsa-miR-4753-3p	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942984	hsa-miR-4756-5p	CLIP-seq
MIRT942985	hsa-miR-4757-5p	CLIP-seq
MIRT942987	hsa-miR-4766-5p	CLIP-seq
MIRT942988	hsa-miR-4768-3p	CLIP-seq
MIRT2518672	hsa-miR-4768-5p	CLIP-seq
MIRT942990	hsa-miR-4782-5p	CLIP-seq
MIRT2214330	hsa-miR-4799-3p	CLIP-seq
MIRT942991	hsa-miR-4800-5p	CLIP-seq
MIRT942992	hsa-miR-488	CLIP-seq
MIRT2518673	hsa-miR-494	CLIP-seq
MIRT2518674	hsa-miR-504	CLIP-seq
MIRT942994	hsa-miR-516b	CLIP-seq
MIRT942996	hsa-miR-541	CLIP-seq
MIRT943000	hsa-miR-574-5p	CLIP-seq
MIRT2387070	hsa-miR-582-3p	CLIP-seq
MIRT2518675	hsa-miR-621	CLIP-seq
MIRT943002	hsa-miR-629	CLIP-seq
MIRT2214337	hsa-miR-634	CLIP-seq
MIRT943006	hsa-miR-654-5p	CLIP-seq
MIRT2518676	hsa-miR-657	CLIP-seq
MIRT943008	hsa-miR-7	CLIP-seq
MIRT943014	hsa-miR-875-3p	CLIP-seq
MIRT2214338	hsa-miR-885-3p	CLIP-seq
MIRT943015	hsa-miR-922	CLIP-seq
MIRT2214339	hsa-miR-940	CLIP-seq
MIRT942891	hsa-miR-122	CLIP-seq
MIRT2518641	hsa-miR-1227	CLIP-seq
MIRT942894	hsa-miR-1236	CLIP-seq
MIRT2679382	hsa-miR-1238	CLIP-seq
MIRT1979201	hsa-miR-1262	CLIP-seq
MIRT2518642	hsa-miR-1272	CLIP-seq
MIRT1979203	hsa-miR-1293	CLIP-seq
MIRT2518643	hsa-miR-1343	CLIP-seq
MIRT1979204	hsa-miR-136	CLIP-seq
MIRT1979205	hsa-miR-1914	CLIP-seq
MIRT2518644	hsa-miR-1976	CLIP-seq
MIRT2679383	hsa-miR-2116	CLIP-seq
MIRT2518645	hsa-miR-2117	CLIP-seq
MIRT2436867	hsa-miR-216b	CLIP-seq
MIRT2518646	hsa-miR-3064-3p	CLIP-seq
MIRT2518647	hsa-miR-3074-5p	CLIP-seq
MIRT2214319	hsa-miR-3123	CLIP-seq
MIRT1979206	hsa-miR-3124-3p	CLIP-seq
MIRT2214320	hsa-miR-3128	CLIP-seq
MIRT2518648	hsa-miR-3140-5p	CLIP-seq
MIRT2518649	hsa-miR-3146	CLIP-seq
MIRT2518650	hsa-miR-3168	CLIP-seq
MIRT2518651	hsa-miR-3545-3p	CLIP-seq
MIRT942925	hsa-miR-3616-3p	CLIP-seq
MIRT2518652	hsa-miR-3665	CLIP-seq
MIRT2518654	hsa-miR-3688-3p	CLIP-seq
MIRT2679384	hsa-miR-3692	CLIP-seq
MIRT2518655	hsa-miR-3919	CLIP-seq
MIRT2518656	hsa-miR-412	CLIP-seq
MIRT1979209	hsa-miR-4259	CLIP-seq
MIRT2214322	hsa-miR-4261	CLIP-seq
MIRT2214323	hsa-miR-4267	CLIP-seq
MIRT1979210	hsa-miR-4269	CLIP-seq
MIRT2518657	hsa-miR-4273	CLIP-seq
MIRT2518658	hsa-miR-433	CLIP-seq
MIRT942945	hsa-miR-4419a	CLIP-seq
MIRT2518659	hsa-miR-4426	CLIP-seq
MIRT2679385	hsa-miR-4428	CLIP-seq
MIRT942947	hsa-miR-4433	CLIP-seq
MIRT942948	hsa-miR-4436b-3p	CLIP-seq
MIRT2518660	hsa-miR-4447	CLIP-seq
MIRT942952	hsa-miR-4459	CLIP-seq
MIRT2518662	hsa-miR-4472	CLIP-seq
MIRT1979212	hsa-miR-4483	CLIP-seq
MIRT942957	hsa-miR-4493	CLIP-seq
MIRT2518663	hsa-miR-4496	CLIP-seq
MIRT942959	hsa-miR-4506	CLIP-seq
MIRT942961	hsa-miR-4510	CLIP-seq
MIRT2214326	hsa-miR-4514	CLIP-seq
MIRT2518664	hsa-miR-4641	CLIP-seq
MIRT2518665	hsa-miR-4647	CLIP-seq
MIRT2518666	hsa-miR-4662b	CLIP-seq
MIRT2679386	hsa-miR-4677-5p	CLIP-seq
MIRT2214327	hsa-miR-4692	CLIP-seq
MIRT2518667	hsa-miR-4694-3p	CLIP-seq
MIRT1979215	hsa-miR-4701-3p	CLIP-seq
MIRT2518668	hsa-miR-4703-3p	CLIP-seq
MIRT2214328	hsa-miR-4720-5p	CLIP-seq
MIRT2518669	hsa-miR-4725-5p	CLIP-seq
MIRT1979216	hsa-miR-4742-5p	CLIP-seq
MIRT2518671	hsa-miR-4753-3p	CLIP-seq
MIRT942983	hsa-miR-4753-5p	CLIP-seq
MIRT942987	hsa-miR-4766-5p	CLIP-seq
MIRT942988	hsa-miR-4768-3p	CLIP-seq
MIRT2518672	hsa-miR-4768-5p	CLIP-seq
MIRT2679387	hsa-miR-4789-3p	CLIP-seq
MIRT2214330	hsa-miR-4799-3p	CLIP-seq
MIRT942992	hsa-miR-488	CLIP-seq
MIRT2518673	hsa-miR-494	CLIP-seq
MIRT2518674	hsa-miR-504	CLIP-seq
MIRT942996	hsa-miR-541	CLIP-seq
MIRT2679388	hsa-miR-548c-3p	CLIP-seq
MIRT1979219	hsa-miR-571	CLIP-seq
MIRT943000	hsa-miR-574-5p	CLIP-seq
MIRT2387070	hsa-miR-582-3p	CLIP-seq
MIRT2518675	hsa-miR-621	CLIP-seq
MIRT943002	hsa-miR-629	CLIP-seq
MIRT2214337	hsa-miR-634	CLIP-seq
MIRT943006	hsa-miR-654-5p	CLIP-seq
MIRT2518676	hsa-miR-657	CLIP-seq
MIRT2214338	hsa-miR-885-3p	CLIP-seq
MIRT2679389	hsa-miR-885-5p	CLIP-seq
MIRT943015	hsa-miR-922	CLIP-seq
MIRT2214339	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002102	Component	Podosome	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IBA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	ISS
GO:0005096	Function	GTPase activator activity	IEA
GO:0005515	Function	Protein binding	IPI	19004829, 31980649, 32203420, 33961781, 35044719
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	19004829
GO:0005886	Component	Plasma membrane	IEA
GO:0007264	Process	Small GTPase-mediated signal transduction	IEA
GO:0007520	Process	Myoblast fusion	IBA
GO:0010634	Process	Positive regulation of epithelial cell migration	IMP	19004829
GO:0016020	Component	Membrane	IEA
GO:0016477	Process	Cell migration	IBA
GO:0016477	Process	Cell migration	IEA
GO:0016601	Process	Rac protein signal transduction	IEA
GO:0031267	Function	Small GTPase binding	IBA
GO:0042995	Component	Cell projection	IEA
GO:0046849	Process	Bone remodeling	IEA
GO:0070161	Component	Anchoring junction	IEA
GO:0071800	Process	Podosome assembly	IEA
GO:1900026	Process	Positive regulation of substrate adhesion-dependent cell spreading	IMP	19004829
GO:1904694	Process	Negative regulation of vascular associated smooth muscle contraction	IMP	22158624
GO:1904754	Process	Positive regulation of vascular associated smooth muscle cell migration	IMP	22158624

Other IDs

• MIM: 616904
• HGNC: 23476
• e!Ensembl: ENSG00000147459

Protein

• UniProt ID: Q9H7D0
• Protein name: Dedicator of cytokinesis protein 5
• Protein function: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and m
• PDB: 7DPA, 8JHK, 8XM7, 8ZJ2, 8ZJI, 8ZJJ, 8ZJK, 8ZJL, 8ZJM
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00018	SH3_1	14 → 61	SH3 domain	Domain
  PF16172	DOCK_N	71 → 434	DOCK N-terminus	Family
  PF14429	DOCK-C2	439 → 636	C2 domain in Dock180 and Zizimin proteins	Domain
  PF06920	DHR-2	1133 → 1635	Dock homology region 2	Family

• Sequence:

  MARWIPTKRQKYGVAIYNYNASQDVELSLQIGDTVHILEMYEGWYRGYTLQNKSKKGIFP
  ETYIHLKEATVEDLGQHETVIPGELPLVQELTSTLREWAVIWRKLYVNNKLTLFRQLQQM
  TYSLIEWRSQILSGTLPKDELAELKKKVTAKIDHGNRMLGLDLVVRDDNGNILDPDETST
  IALFKAHEVASKRIEEKIQEEKSILQNLDLRGQSIFSTIHTYGLYVNFKNFVCNIGEDAE
  LFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQAVFTDLSSMDLIRPRVSLVCQI
  VRVGHMELKEGKKHTCGLRRPFGVAVMDITDIIHGKVDDEEKQHFIPFQQIAMETYIRQR
  QLIMSPLITSHVIGENEPLTSVLNKVIAAKEVNHKGQGLWVSLKLLPGDLTQVQKNFSHL
  VDRSTAIARKMGFPEIILPGDVRNDIYVTLIHGEFDKGKKKTPKNVEVTMSVHDEEGKLL
  EKAIHPGAGYEGISEYKSVVYYQVKQPCWYETVKVSIAIEEVTRCHIRFTFRHRSSQETR
  DKSERAFGVAFVKLMNPDGTTLQDGRHDLVVYKGDNKKMEDAKFYLTLPGTKMEMEEKEL
  QASKNLVTFTPSKDSTKDSFQIATLICSTKLTQNVDLLGLLNWRSNSQNIKHNLKKLMEV
  DGGEIVKFLQDTLDALFNIMMEMSDSETYDFLVFDALVFIISLIGDIKFQHFNPVLETYI
  YKHFSATLAYVKLSKVLNFYVANADDSSKTELLFAALKALKYLFRFIIQSRVLYLRFYGQ
  SKDGDEFNNSIRQLFLAFNMLMDRPLEEAVKIKGAALKYLPSIINDVKLVFDPVELSVLF
  CKFIQSIPDNQLVRQKLNCMTKIVESTLFRQSECREVLLPLLTDQLSGQLDDNSNKPDHE
  ASSQLLSNILEVLDRKDVGATAVHIQLIMERLLRRINRTVIGMNRQSPHIGSFVACMIAL
  LQQMDDSHYSHYISTFKTRQDIIDFLMETFIMFKDLIGKNVYAKDWMVMNMTQNRVFLRA
  INQFAEVLTRFFMDQASFELQLWNNYFHLAVAFLTHESLQLETFSQAKRNKIVKKYGDMR
  KEIGFRIRDMWYNLGPHKIKFIPSMVGPILEVTLTPEVELRKATIPIFFDMMQCEFNFSG
  NGNFHMFENELITKLDQEVEGGRGDEQYKVLLEKLLLEHCRKHKYLSSSGEVFALLVSSL
  LENLLDYRTIIMQDESKENRMSCTVNVLNFYKEKKREDIYIRYLYKLRDLHRDCENYTEA
  AYTLLLHAELLQWSDKPCVPHLLQKDSYYVYTQQELKEKLYQEIISYFDKGKMWEKAIKL
  SKELAETYESKVFDYEGLGNLLKKRASFYENIIKAMRPQPEYFAVGYYGQGFPSFLRNKI
  FIYRGKEYERREDFSLRLLTQFPNAEKMTSTTPPGEDIKSSPKQYMQCFTVKPVMSLPPS
  YKDKPVPEQILNYYRANEVQQFRYSRPFRKGEKDPDNEFATMWIERTTYTTAYTFPGILK
  WFEVKQISTEEISPLENAIETMELTNERISNCVQQHAWDRSLSVHPLSMLLSGIVDPAVM
  GGFSNYEKAFFTEKYLQEHPEDQEKVELLKRLIALQMPLLTEGIRIHGEKLTEQLKPLHE
  RLSSCFRELKEKVEKHYGVITLPPNLTERKQSRTGSIVLPYIMSSTLRRLSITSVTSSVV
  STSSNSSDNAPSRPGSDGSILEPLLERRASSGARVEDLSLREENSENRISKFKRKDWSLS
  KSQVIAEKAPEPDLMSPTRKAQRPKSLQLMDNRLSPFHGSSPPQSTPLSPPPLTPKATRT
  LSSPSLQTDGIAATPVPPPPPPKSKPYEGSQRNSTELAPPLPVRREAKAPPPPPPKARKS
  GIPTSEPGSQ

• Sequence length: 1870

Pathways

Reactome:

Factors involved in megakaryocyte development and platelet production

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
CENTRAL NERVOUS SYSTEM CANCER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CORONARY ARTERY DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Nonpapillary renal cell carcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OLIGODENDROGLIOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UTERINE FIBROID	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Asthma	Asthma	BEFREE	28479334		★☆☆☆☆ Found in Text Mining only
Graves Ophthalmopathy	Graves ophthalmopathy	Pubtator	40065401	Associate	★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	30668141		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	29945995, 30668141		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	29945995		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	22595969		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	Pubtator	22595969, 28479334, 38110883	Associate	★☆☆☆☆ Found in Text Mining only
Obesity, Morbid	Obesity	BEFREE	22595969		★☆☆☆☆ Found in Text Mining only
Osteoporosis	Osteoporosis	BEFREE	29089502		★☆☆☆☆ Found in Text Mining only
Osteosarcoma	Osteosarcoma	Pubtator	20465837	Associate	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Ovarian neoplasm	Pubtator	32180586	Associate	★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	29945995, 37434235	Associate	★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of the head and neck	Carcinoma Of The Head And Neck	BEFREE	29945995		★☆☆☆☆ Found in Text Mining only