DCAKD (dephospho-CoA kinase domain containing)

Gene

• Entrez ID: 79877
• Gene name: Dephospho-CoA kinase domain containing
• Gene symbol: DCAKD
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17q21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018751	hsa-miR-335-5p	Microarray	18185580
MIRT024049	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT607535	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT607534	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT526602	hsa-miR-4802-3p	PAR-CLIP	22012620
MIRT526601	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT526600	hsa-miR-4261	PAR-CLIP	22012620
MIRT526599	hsa-miR-133a-3p	PAR-CLIP	22012620
MIRT526599	hsa-miR-133a-3p	PAR-CLIP	22012620
MIRT526598	hsa-miR-133b	PAR-CLIP	22012620
MIRT440844	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440844	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT607534	hsa-miR-574-5p	PAR-CLIP	26701625
MIRT607535	hsa-miR-6867-5p	PAR-CLIP	26701625
MIRT607534	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT607534	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT607534	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT607535	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT607535	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT607535	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT526602	hsa-miR-4802-3p	PAR-CLIP	22012620
MIRT526601	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT526600	hsa-miR-4261	PAR-CLIP	22012620
MIRT526599	hsa-miR-133a-3p	PAR-CLIP	22012620
MIRT526599	hsa-miR-133a-3p	PAR-CLIP	22012620
MIRT526598	hsa-miR-133b	PAR-CLIP	22012620
MIRT925620	hsa-miR-124	CLIP-seq
MIRT925621	hsa-miR-147	CLIP-seq
MIRT925622	hsa-miR-150	CLIP-seq
MIRT925623	hsa-miR-15a	CLIP-seq
MIRT925624	hsa-miR-15b	CLIP-seq
MIRT925625	hsa-miR-16	CLIP-seq
MIRT925626	hsa-miR-1915	CLIP-seq
MIRT925627	hsa-miR-195	CLIP-seq
MIRT925628	hsa-miR-1972	CLIP-seq
MIRT925629	hsa-miR-214	CLIP-seq
MIRT925630	hsa-miR-31	CLIP-seq
MIRT925631	hsa-miR-3151	CLIP-seq
MIRT925632	hsa-miR-3185	CLIP-seq
MIRT925633	hsa-miR-3619-5p	CLIP-seq
MIRT925634	hsa-miR-424	CLIP-seq
MIRT925635	hsa-miR-4493	CLIP-seq
MIRT925636	hsa-miR-4645-5p	CLIP-seq
MIRT925637	hsa-miR-4673	CLIP-seq
MIRT925638	hsa-miR-4713-5p	CLIP-seq
MIRT925639	hsa-miR-4726-3p	CLIP-seq
MIRT925640	hsa-miR-4733-5p	CLIP-seq
MIRT925641	hsa-miR-497	CLIP-seq
MIRT925642	hsa-miR-506	CLIP-seq
MIRT925643	hsa-miR-532-3p	CLIP-seq
MIRT925644	hsa-miR-644	CLIP-seq
MIRT925645	hsa-miR-657	CLIP-seq
MIRT925646	hsa-miR-665	CLIP-seq
MIRT925647	hsa-miR-761	CLIP-seq
MIRT925648	hsa-miR-939	CLIP-seq
MIRT925649	hsa-miR-1254	CLIP-seq
MIRT925650	hsa-miR-143	CLIP-seq
MIRT925651	hsa-miR-3116	CLIP-seq
MIRT925652	hsa-miR-339-5p	CLIP-seq
MIRT925653	hsa-miR-3545-3p	CLIP-seq
MIRT925654	hsa-miR-3617	CLIP-seq
MIRT925655	hsa-miR-3942-3p	CLIP-seq
MIRT925656	hsa-miR-4283	CLIP-seq
MIRT925657	hsa-miR-4489	CLIP-seq
MIRT925658	hsa-miR-4511	CLIP-seq
MIRT925659	hsa-miR-4539	CLIP-seq
MIRT925660	hsa-miR-4667-5p	CLIP-seq
MIRT925661	hsa-miR-4700-5p	CLIP-seq
MIRT925662	hsa-miR-4722-3p	CLIP-seq
MIRT925663	hsa-miR-4756-3p	CLIP-seq
MIRT925664	hsa-miR-4770	CLIP-seq
MIRT925665	hsa-miR-4794	CLIP-seq
MIRT925666	hsa-miR-485-5p	CLIP-seq
MIRT925667	hsa-miR-486-3p	CLIP-seq
MIRT925668	hsa-miR-515-3p	CLIP-seq
MIRT925669	hsa-miR-519e	CLIP-seq
MIRT925670	hsa-miR-548b-3p	CLIP-seq
MIRT925671	hsa-miR-548v	CLIP-seq
MIRT925672	hsa-miR-550a	CLIP-seq
MIRT925673	hsa-miR-637	CLIP-seq
MIRT925674	hsa-miR-641	CLIP-seq
MIRT925675	hsa-miR-661	CLIP-seq
MIRT925623	hsa-miR-15a	CLIP-seq
MIRT925624	hsa-miR-15b	CLIP-seq
MIRT925625	hsa-miR-16	CLIP-seq
MIRT925626	hsa-miR-1915	CLIP-seq
MIRT925627	hsa-miR-195	CLIP-seq
MIRT925628	hsa-miR-1972	CLIP-seq
MIRT925629	hsa-miR-214	CLIP-seq
MIRT925633	hsa-miR-3619-5p	CLIP-seq
MIRT925634	hsa-miR-424	CLIP-seq
MIRT925639	hsa-miR-4726-3p	CLIP-seq
MIRT925641	hsa-miR-497	CLIP-seq
MIRT925645	hsa-miR-657	CLIP-seq
MIRT925646	hsa-miR-665	CLIP-seq
MIRT925647	hsa-miR-761	CLIP-seq
MIRT1974278	hsa-miR-1193	CLIP-seq
MIRT925620	hsa-miR-124	CLIP-seq
MIRT1974279	hsa-miR-1265	CLIP-seq
MIRT1974280	hsa-miR-1273d	CLIP-seq
MIRT925621	hsa-miR-147	CLIP-seq
MIRT925623	hsa-miR-15a	CLIP-seq
MIRT925624	hsa-miR-15b	CLIP-seq
MIRT925625	hsa-miR-16	CLIP-seq
MIRT925627	hsa-miR-195	CLIP-seq
MIRT925629	hsa-miR-214	CLIP-seq
MIRT1974281	hsa-miR-2392	CLIP-seq
MIRT925630	hsa-miR-31	CLIP-seq
MIRT1974282	hsa-miR-3120-3p	CLIP-seq
MIRT1974283	hsa-miR-3125	CLIP-seq
MIRT925631	hsa-miR-3151	CLIP-seq
MIRT1974284	hsa-miR-3152-3p	CLIP-seq
MIRT1974285	hsa-miR-3177-5p	CLIP-seq
MIRT1974286	hsa-miR-3184	CLIP-seq
MIRT925633	hsa-miR-3619-5p	CLIP-seq
MIRT1974287	hsa-miR-3662	CLIP-seq
MIRT1974288	hsa-miR-3916	CLIP-seq
MIRT1974289	hsa-miR-409-3p	CLIP-seq
MIRT1974290	hsa-miR-423-5p	CLIP-seq
MIRT925634	hsa-miR-424	CLIP-seq
MIRT925656	hsa-miR-4283	CLIP-seq
MIRT925657	hsa-miR-4489	CLIP-seq
MIRT925635	hsa-miR-4493	CLIP-seq
MIRT1974291	hsa-miR-4496	CLIP-seq
MIRT1974292	hsa-miR-4716-3p	CLIP-seq
MIRT1974293	hsa-miR-4723-5p	CLIP-seq
MIRT1974294	hsa-miR-4764-5p	CLIP-seq
MIRT925641	hsa-miR-497	CLIP-seq
MIRT1974295	hsa-miR-500a	CLIP-seq
MIRT925642	hsa-miR-506	CLIP-seq
MIRT1974296	hsa-miR-571	CLIP-seq
MIRT1974297	hsa-miR-602	CLIP-seq
MIRT1974298	hsa-miR-619	CLIP-seq
MIRT925644	hsa-miR-644	CLIP-seq
MIRT925645	hsa-miR-657	CLIP-seq
MIRT925675	hsa-miR-661	CLIP-seq
MIRT925646	hsa-miR-665	CLIP-seq
MIRT925647	hsa-miR-761	CLIP-seq
MIRT925648	hsa-miR-939	CLIP-seq
MIRT1974278	hsa-miR-1193	CLIP-seq
MIRT925620	hsa-miR-124	CLIP-seq
MIRT925650	hsa-miR-143	CLIP-seq
MIRT925629	hsa-miR-214	CLIP-seq
MIRT1974281	hsa-miR-2392	CLIP-seq
MIRT925630	hsa-miR-31	CLIP-seq
MIRT1974282	hsa-miR-3120-3p	CLIP-seq
MIRT2209711	hsa-miR-3130-3p	CLIP-seq
MIRT2209712	hsa-miR-3155	CLIP-seq
MIRT2209713	hsa-miR-3155b	CLIP-seq
MIRT2209714	hsa-miR-3157-5p	CLIP-seq
MIRT2209715	hsa-miR-3194-3p	CLIP-seq
MIRT925652	hsa-miR-339-5p	CLIP-seq
MIRT2209716	hsa-miR-3591-3p	CLIP-seq
MIRT925654	hsa-miR-3617	CLIP-seq
MIRT925633	hsa-miR-3619-5p	CLIP-seq
MIRT2209717	hsa-miR-3938	CLIP-seq
MIRT2209718	hsa-miR-4428	CLIP-seq
MIRT2209719	hsa-miR-4477a	CLIP-seq
MIRT925635	hsa-miR-4493	CLIP-seq
MIRT925658	hsa-miR-4511	CLIP-seq
MIRT2209720	hsa-miR-4640-3p	CLIP-seq
MIRT2209721	hsa-miR-4640-5p	CLIP-seq
MIRT2209722	hsa-miR-4726-5p	CLIP-seq
MIRT2209723	hsa-miR-4755-3p	CLIP-seq
MIRT925663	hsa-miR-4756-3p	CLIP-seq
MIRT925664	hsa-miR-4770	CLIP-seq
MIRT2209724	hsa-miR-4793-3p	CLIP-seq
MIRT2209725	hsa-miR-484	CLIP-seq
MIRT925642	hsa-miR-506	CLIP-seq
MIRT925670	hsa-miR-548b-3p	CLIP-seq
MIRT2209726	hsa-miR-603	CLIP-seq
MIRT925674	hsa-miR-641	CLIP-seq
MIRT925645	hsa-miR-657	CLIP-seq
MIRT2209727	hsa-miR-760	CLIP-seq
MIRT925647	hsa-miR-761	CLIP-seq
MIRT2513459	hsa-miR-154	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0004140	Function	Dephospho-CoA kinase activity	EXP	11923312
GO:0004140	Function	Dephospho-CoA kinase activity	IBA
GO:0004140	Function	Dephospho-CoA kinase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0015937	Process	Coenzyme A biosynthetic process	IBA
GO:0015937	Process	Coenzyme A biosynthetic process	IEA
GO:0015937	Process	Coenzyme A biosynthetic process	TAS
GO:0016020	Component	Membrane	HDA	19946888

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8WVC6
• Protein name: Dephospho-CoA kinase domain-containing protein
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01121	CoaE	2 → 183	Dephospho-CoA kinase	Domain

• Sequence:

  MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVMARHVVQPGYPAHRRIVEVFGTEVLLE
  NGDINRKVLGDLIFNQPDRRQLLNAITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFET
  KKLLKYMKHTVVVYCDRDTQLARLMRRNSLNRKDAEARINAQLPLTDKARMARHVLDNSG
  EWSVTKRQVILLHTELERSLEYLPLRFGVLTGLAAIASLLYLLTHYLLPYA

• Sequence length: 231

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ALZHEIMER DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CRANIOFACIAL MICROSOMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Huntington Disease	Huntington disease	Pubtator	33049985	Associate	★☆☆☆☆ Found in Text Mining only
Parkinson Disease	Parkinson disease	Pubtator	32066731	Associate	★☆☆☆☆ Found in Text Mining only