CAMKMT (calmodulin-lysine N-methyltransferase)

Gene

• Entrez ID: 79823
• Gene name: Calmodulin-lysine N-methyltransferase
• Gene symbol: CAMKMT
• Synonyms (NCBI Gene): C2orf34, CLNMT, CaM KMT, Cam, KMT
• Chromosome: 2
• Chromosome location: 2p21
• Summary: This gene encodes a class I protein methyltransferase that acts in the formation of trimethyllysine in calmodulin. The protein contains a AdoMet-binding motif and may play a role in calcium-dependent signaling. [provided by RefSeq, Sep 2012]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT030210	hsa-miR-26b-5p	Microarray	19088304
MIRT860541	hsa-miR-1226	CLIP-seq
MIRT860542	hsa-miR-1286	CLIP-seq
MIRT860543	hsa-miR-1296	CLIP-seq
MIRT860544	hsa-miR-1297	CLIP-seq
MIRT860545	hsa-miR-1324	CLIP-seq
MIRT860546	hsa-miR-197	CLIP-seq
MIRT860547	hsa-miR-21	CLIP-seq
MIRT860548	hsa-miR-224	CLIP-seq
MIRT860549	hsa-miR-26a	CLIP-seq
MIRT860550	hsa-miR-26b	CLIP-seq
MIRT860551	hsa-miR-2909	CLIP-seq
MIRT860552	hsa-miR-375	CLIP-seq
MIRT860553	hsa-miR-4436b-3p	CLIP-seq
MIRT860554	hsa-miR-4465	CLIP-seq
MIRT860555	hsa-miR-4514	CLIP-seq
MIRT860556	hsa-miR-4643	CLIP-seq
MIRT860557	hsa-miR-466	CLIP-seq
MIRT860558	hsa-miR-4692	CLIP-seq
MIRT860559	hsa-miR-4733-3p	CLIP-seq
MIRT860560	hsa-miR-4761-3p	CLIP-seq
MIRT860561	hsa-miR-4789-3p	CLIP-seq
MIRT860562	hsa-miR-4789-5p	CLIP-seq
MIRT860563	hsa-miR-590-5p	CLIP-seq
MIRT860564	hsa-miR-759	CLIP-seq
MIRT860541	hsa-miR-1226	CLIP-seq
MIRT860544	hsa-miR-1297	CLIP-seq
MIRT860545	hsa-miR-1324	CLIP-seq
MIRT860546	hsa-miR-197	CLIP-seq
MIRT860547	hsa-miR-21	CLIP-seq
MIRT860548	hsa-miR-224	CLIP-seq
MIRT860549	hsa-miR-26a	CLIP-seq
MIRT860550	hsa-miR-26b	CLIP-seq
MIRT860552	hsa-miR-375	CLIP-seq
MIRT860554	hsa-miR-4465	CLIP-seq
MIRT860555	hsa-miR-4514	CLIP-seq
MIRT860558	hsa-miR-4692	CLIP-seq
MIRT860559	hsa-miR-4733-3p	CLIP-seq
MIRT860562	hsa-miR-4789-5p	CLIP-seq
MIRT860563	hsa-miR-590-5p	CLIP-seq
MIRT860541	hsa-miR-1226	CLIP-seq
MIRT860544	hsa-miR-1297	CLIP-seq
MIRT860545	hsa-miR-1324	CLIP-seq
MIRT860546	hsa-miR-197	CLIP-seq
MIRT860547	hsa-miR-21	CLIP-seq
MIRT860548	hsa-miR-224	CLIP-seq
MIRT860549	hsa-miR-26a	CLIP-seq
MIRT860550	hsa-miR-26b	CLIP-seq
MIRT860554	hsa-miR-4465	CLIP-seq
MIRT860555	hsa-miR-4514	CLIP-seq
MIRT860556	hsa-miR-4643	CLIP-seq
MIRT860557	hsa-miR-466	CLIP-seq
MIRT860558	hsa-miR-4692	CLIP-seq
MIRT860559	hsa-miR-4733-3p	CLIP-seq
MIRT860561	hsa-miR-4789-3p	CLIP-seq
MIRT860562	hsa-miR-4789-5p	CLIP-seq
MIRT860563	hsa-miR-590-5p	CLIP-seq
MIRT860542	hsa-miR-1286	CLIP-seq
MIRT860543	hsa-miR-1296	CLIP-seq
MIRT2496188	hsa-miR-185	CLIP-seq
MIRT2496189	hsa-miR-1908	CLIP-seq
MIRT860547	hsa-miR-21	CLIP-seq
MIRT860551	hsa-miR-2909	CLIP-seq
MIRT2496190	hsa-miR-3135b	CLIP-seq
MIRT2496191	hsa-miR-3616-3p	CLIP-seq
MIRT2496192	hsa-miR-4300	CLIP-seq
MIRT2496193	hsa-miR-4306	CLIP-seq
MIRT2496194	hsa-miR-4419a	CLIP-seq
MIRT860553	hsa-miR-4436b-3p	CLIP-seq
MIRT2496195	hsa-miR-4487	CLIP-seq
MIRT2496196	hsa-miR-4510	CLIP-seq
MIRT860555	hsa-miR-4514	CLIP-seq
MIRT860556	hsa-miR-4643	CLIP-seq
MIRT2496197	hsa-miR-4644	CLIP-seq
MIRT860557	hsa-miR-466	CLIP-seq
MIRT860558	hsa-miR-4692	CLIP-seq
MIRT2496198	hsa-miR-4706	CLIP-seq
MIRT2496199	hsa-miR-4728-5p	CLIP-seq
MIRT2496200	hsa-miR-4749-5p	CLIP-seq
MIRT860560	hsa-miR-4761-3p	CLIP-seq
MIRT860561	hsa-miR-4789-3p	CLIP-seq
MIRT860562	hsa-miR-4789-5p	CLIP-seq
MIRT2496201	hsa-miR-548u	CLIP-seq
MIRT2496202	hsa-miR-583	CLIP-seq
MIRT860563	hsa-miR-590-5p	CLIP-seq
MIRT2496203	hsa-miR-663	CLIP-seq
MIRT860564	hsa-miR-759	CLIP-seq
MIRT2496204	hsa-miR-920	CLIP-seq
MIRT860542	hsa-miR-1286	CLIP-seq
MIRT860543	hsa-miR-1296	CLIP-seq
MIRT860547	hsa-miR-21	CLIP-seq
MIRT860551	hsa-miR-2909	CLIP-seq
MIRT860553	hsa-miR-4436b-3p	CLIP-seq
MIRT860555	hsa-miR-4514	CLIP-seq
MIRT860556	hsa-miR-4643	CLIP-seq
MIRT860557	hsa-miR-466	CLIP-seq
MIRT860558	hsa-miR-4692	CLIP-seq
MIRT860560	hsa-miR-4761-3p	CLIP-seq
MIRT860561	hsa-miR-4789-3p	CLIP-seq
MIRT860562	hsa-miR-4789-5p	CLIP-seq
MIRT2496201	hsa-miR-548u	CLIP-seq
MIRT860563	hsa-miR-590-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IDA	23349634
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0007005	Process	Mitochondrion organization	IEA
GO:0008168	Function	Methyltransferase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0018025	Function	Calmodulin-lysine N-methyltransferase activity	IBA
GO:0018025	Function	Calmodulin-lysine N-methyltransferase activity	IEA
GO:0018025	Function	Calmodulin-lysine N-methyltransferase activity	TAS
GO:0022400	Process	Regulation of opsin-mediated signaling pathway	TAS
GO:0031072	Function	Heat shock protein binding	IPI	23349634
GO:0032259	Process	Methylation	IEA
GO:0032991	Component	Protein-containing complex	IDA	23349634
GO:0032991	Component	Protein-containing complex	IEA

Other IDs

• MIM: 609559
• HGNC: 26276
• e!Ensembl: ENSG00000143919

Protein

• UniProt ID: Q7Z624
• Protein name: Calmodulin-lysine N-methyltransferase (CLNMT) (CaM KMT) (EC 2.1.1.60)
• Protein function: Catalyzes the trimethylation of 'Lys-116' in calmodulin.
• PDB: 4PWY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10294	Methyltransf_16	110 → 278	Lysine methyltransferase	Family

• Tissue specificity: TISSUE SPECIFICITY: Isoform 1 is expressed in brain, liver, muscle colon and lung. Isoform 2 is expressed in colon, testis, kidney and brain. Isoform 1 and isoform 2 are expressed in normal lymphoblastoid cells but not in lymphoblastoid cells from patient
• Sequence:

  MESRVADAGTGETARAAGGSPAVGCTTRGPVVSAPLGAARWKLLRQVLKQKHLDDCLRHV
  SVRRFESFNLFSVTEGKERETEEEVGAWVQYTSIFCPEYSISLRHNSGSLNVEDVLTSFD
  NTGNVCIWPSEEVLAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGN
  EKAIRNVQDIITRNQKAGVFKTQKISSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYR
  ASLVDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKAGFCIQRHENYDEHISNFHSKLK
  KENPDIYEENLHYPLLLILTKHG

• Sequence length: 323

Pathways

KEGG:

Lysine degradation
Metabolic pathways

Reactome:

Inactivation, recovery and regulation of the phototransduction cascade
Protein methylation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATYPICAL HYPOTONIA CYSTINURIA SYNDROME	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATYPICAL HYPOTONIA-CYSTINURIA SYNDROME	—	Orphanet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BIPOLAR DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CANNABIS DEPENDENCE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CHOLELITHIASIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL COORDINATION DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEVELOPMENTAL DISABILITIES	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ESSENTIAL TREMOR	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEARNING DISABILITIES	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEARNING DISORDERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL MYOPATHIES	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOTOR SKILLS DISORDERS	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBSTRUCTIVE SLEEP APNEA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN SEROUS CARCINOMA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
2p21 microdeletion syndrome	2p21 microdeletion syndrome	ORPHANET_DG	11524703		★☆☆☆☆ Found in Text Mining only
2p21 microdeletion syndrome	2p21 microdeletion syndrome	Orphanet			★☆☆☆☆ Found in Text Mining only
2p21 microdeletion syndrome without cystinuria	2p21 microdeletion syndrome without cystinuria	ORPHANET_DG	23794250		★☆☆☆☆ Found in Text Mining only
2p21 microdeletion syndrome without cystinuria	2p21 microdeletion syndrome without cystinuria	Orphanet			★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Adenocarcinoma	BEFREE	8169749		★☆☆☆☆ Found in Text Mining only
Adenocarcinoma of colon	Adenocarcinoma Of Colon	BEFREE	26824338		★☆☆☆☆ Found in Text Mining only
Adenoid Cystic Carcinoma	Adenocarcinoma	BEFREE	9374166		★☆☆☆☆ Found in Text Mining only
Adult Learning Disorders	Learning Disorders	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Adult onset autosomal dominant leukodystrophy	Leukodystrophy	BEFREE	19725832		★☆☆☆☆ Found in Text Mining only
Anemia, Sickle Cell	Anemia	BEFREE	14755370		★☆☆☆☆ Found in Text Mining only
Arthritis	Arthritis	BEFREE	29609944		★☆☆☆☆ Found in Text Mining only
Atypical hypotonia-cystinuria syndrome	Hypotonia-Cystinuria Syndrome	Orphanet			★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	BEFREE	11033343		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bipolar Disorder	Bipolar Disorder	GWASDB_DG	21738484		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Bladder Neoplasm	Bladder Neoplasm	BEFREE	8758907		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	11964043, 1690316, 1793731, 19787228, 9284823		★☆☆☆☆ Found in Text Mining only
Carcinoma	Carcinoma	BEFREE	19787228, 8169749		★☆☆☆☆ Found in Text Mining only
Carcinoma of bladder	Bladder carcinoma	BEFREE	8758907		★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	26761817		★☆☆☆☆ Found in Text Mining only
CATARACT, MARNER TYPE	Cataract	BEFREE	10082134, 1490146, 24509172, 30168728, 31738061, 7955125		★☆☆☆☆ Found in Text Mining only
Centronuclear myopathy	Centronuclear Myopathy	BEFREE	7969799		★☆☆☆☆ Found in Text Mining only
Child Development Deviations	Development Disorder	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Child Development Disorders, Specific	Development Disorder	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Chronic schizophrenia	Schizophrenia	BEFREE	10696830		★☆☆☆☆ Found in Text Mining only
Class III malocclusion	Malocclusion	BEFREE	29970262		★☆☆☆☆ Found in Text Mining only
Colon Carcinoma	Colon Carcinoma	BEFREE	17699774, 8396566		★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	8169749		★☆☆☆☆ Found in Text Mining only
Craniosynostosis	Craniosynostosis	BEFREE	28921242		★☆☆☆☆ Found in Text Mining only
Crohn Disease	Crohn Disease	BEFREE	19212205		★☆☆☆☆ Found in Text Mining only
Cystinuria	Cystinuria	HPO_DG			★☆☆☆☆ Found in Text Mining only
Degenerative polyarthritis	Arthritis	BEFREE	28974401		★☆☆☆☆ Found in Text Mining only
Delirium	Delirium	BEFREE	27108353, 27251666, 28039082, 28173895, 28903799, 28947274, 29103316, 29171992, 29370764, 30506177, 30664239, 30804030, 30899957, 30920404, 31127777, 31467255, 31605539, 31695347		★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	15820228		★☆☆☆☆ Found in Text Mining only
Developmental Coordination Disorder	Developmental dyspraxia	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Developmental Disabilities	Development Disorder	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ectodermal Dysplasia	Ectodermal Dysplasia	BEFREE	30192352		★☆☆☆☆ Found in Text Mining only
Endometrial Carcinoma	Endometrial carcinoma	BEFREE	30851892		★☆☆☆☆ Found in Text Mining only
Frontal bossing	Frontal bossing	HPO_DG			★☆☆☆☆ Found in Text Mining only
Gallbladder Carcinoma	Gallbladder cancer	BEFREE	22200632		★☆☆☆☆ Found in Text Mining only
Gastrointestinal Stromal Tumors	Gastrointestinal stromal tumor	BEFREE	31331555		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	10697494, 29228563		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	10697494, 29228563		★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	BEFREE	16322240		★☆☆☆☆ Found in Text Mining only
Global developmental delay	Developmental Delay	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hereditary pancreatitis	Hereditary Pancreatitis	BEFREE	15668900		★☆☆☆☆ Found in Text Mining only
Holoprosencephaly	Holoprosencephaly	BEFREE	12820004		★☆☆☆☆ Found in Text Mining only
Hypoglycemia	Hypoglycemia	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypogonadism	Hypogonadism	HPO_DG			★☆☆☆☆ Found in Text Mining only
Hypothyroidism	Hypothyroidism	BEFREE	3297787		★☆☆☆☆ Found in Text Mining only
Hypotonia-Cystinuria Syndrome	Hypotonia-Cystinuria Syndrome	BEFREE	18781961, 28726805		★☆☆☆☆ Found in Text Mining only
Hypotonia-Cystinuria Syndrome	Hypotonia-Cystinuria Syndrome	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
ICHTHYOSIS PREMATURITY SYNDROME	ICHTHYOSIS PREMATURITY SYNDROME	BEFREE	29605190		★☆☆☆☆ Found in Text Mining only
Impaired cognition	Impaired Cognition	BEFREE	11033343		★☆☆☆☆ Found in Text Mining only
Learning Disabilities	Learning Disorders	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Learning Disorders	Learning Disorders	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Learning Disturbance	Learning Disorders	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Lissencephaly	Lissencephaly	BEFREE	12820004		★☆☆☆☆ Found in Text Mining only
Luft Disease	Luft Disease	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Lupus Erythematosus, Systemic	Lupus Erythematosus	BEFREE	31820195		★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	BEFREE	27599538		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin	Non-Hodgkin lymphoma	BEFREE	26341817, 27840970, 28395594		★☆☆☆☆ Found in Text Mining only
Lymphoma, Non-Hodgkin, Familial	Lymphoma	BEFREE	26341817, 28395594		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	11313949, 11964043, 1793731, 19787228, 9704623		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of endometrium	Endometrial Cancer	BEFREE	30851892		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of gallbladder	Gallbladder cancer	BEFREE	22200632		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of kidney	Kidney Cancer	BEFREE	21880579		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of ovary	Ovarian cancer	BEFREE	26761817		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	10597733, 7796410, 8758907		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of skin	Skin cancer	BEFREE	15278364		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	24796534		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of urinary bladder	Urinary bladder cancer	BEFREE	8758907		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	1706237, 21880579, 22889191, 30552257, 30834992, 30935516, 31331555		★☆☆☆☆ Found in Text Mining only
Malignant tumor of colon	Colonic Neoplasms	BEFREE	17699774, 8396566		★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	28533307		★☆☆☆☆ Found in Text Mining only
MASA SYNDROME (disorder)	MASA syndrome	BEFREE	7562969		★☆☆☆☆ Found in Text Mining only
Megaconial Myopathies	Megaconial Myopathies	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
melanoma	Melanoma	BEFREE	11498790, 12823444, 1469290, 29763480, 31826047, 9284823		★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	BEFREE	15668900		★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	15820228		★☆☆☆☆ Found in Text Mining only
Mesothelioma	Mesothelioma	BEFREE	7955125		★☆☆☆☆ Found in Text Mining only
Metastatic melanoma	Metastatic Melanoma	BEFREE	11255016		★☆☆☆☆ Found in Text Mining only
Mitochondrial Myopathies	Mitochondrial myopathy	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Moderate intellectual disability	Mental retardation	HPO_DG			★☆☆☆☆ Found in Text Mining only
Mood Disorders	Mood Disorder	BEFREE	10696830		★☆☆☆☆ Found in Text Mining only
Motor Skills Disorders	Motor Skills Disorders	CTD_human_DG	26247364		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Multiple Myeloma	Multiple myeloma	BEFREE	14633719, 1706237, 23760401, 24037419, 26453405, 26710889, 27189701, 27258734, 28238095, 31540771, 9436925		★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Multiple Sclerosis	BEFREE	24430173		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10597733, 10697494, 11313949, 11964043, 1706237, 17546603, 17952127, 19787228, 20421925, 21602664, 22889191, 23000338, 23527098, 24509172, 24703465, 27498840, 28634389, 28838999, 29133037, 29228563, 29763480, 30170067, 7542254, 7796410, 8188295, 8758907, 9284823, 9374166		★☆☆☆☆ Found in Text Mining only
Nephrolithiasis	Nephrolithiasis	HPO_DG			★☆☆☆☆ Found in Text Mining only
Neuroblastoma	Neuroblastoma	BEFREE	10495434, 24509172, 2471777, 27498840		★☆☆☆☆ Found in Text Mining only
ovarian neoplasm	Ovarian neoplasm	BEFREE	26761817		★☆☆☆☆ Found in Text Mining only
Paraganglioma	Paraganglioma	BEFREE	31442521		★☆☆☆☆ Found in Text Mining only
Pleoconial Myopathies	Pleoconial myopathy	CTD_human_DG	26247364		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	10597733, 7796410, 8758907		★☆☆☆☆ Found in Text Mining only
Renal carcinoma	Renal Carcinoma	BEFREE	10495434, 21880579		★☆☆☆☆ Found in Text Mining only
Renal Cell Carcinoma	Renal Carcinoma	BEFREE	10495434		★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	31820195		★☆☆☆☆ Found in Text Mining only
Sarcoma	Sarcoma	BEFREE	31331555		★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	10696830, 11033343, 11681838, 20157312, 9098580		★☆☆☆☆ Found in Text Mining only
Sleep Apnea, Obstructive	Sleep Apnea	BEFREE	31331855		★☆☆☆☆ Found in Text Mining only
Slipped Capital Femoral Epiphyses	Slipped Capital Femoral Epiphyses	BEFREE	29426010		★☆☆☆☆ Found in Text Mining only
Small cell carcinoma of lung	Lung carcinoma	BEFREE	20421925, 8075973		★☆☆☆☆ Found in Text Mining only
Spastic Paraplegia	Spastic Paraplegia	BEFREE	7562969		★☆☆☆☆ Found in Text Mining only
Specific language impairment	Specific Language Impairment	BEFREE	20157312		★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma of esophagus	Esophagus Neoplasm	BEFREE	31517842		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	24796534		★☆☆☆☆ Found in Text Mining only
Testicular Germ Cell Tumor	Testicular Germ Cell Tumor	BEFREE	28838999		★☆☆☆☆ Found in Text Mining only
Trigeminal Neuralgia	Trigeminal neuralgia	BEFREE	31560737		★☆☆☆☆ Found in Text Mining only
Ulcerative Colitis	Ulcerative colitis	BEFREE	19212205		★☆☆☆☆ Found in Text Mining only
VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)	Catecholaminergic polymorphic ventricular tachycardia	BEFREE	29720499		★☆☆☆☆ Found in Text Mining only
X-linked hydrocephalus syndrome	Hydrocephalus Syndrome, X-Linked	BEFREE	7562969, 9195224		★☆☆☆☆ Found in Text Mining only