Gene Gene information from NCBI Gene database.
Entrez ID 79807
Gene name Glutathione S-transferase C-terminal domain containing
Gene symbol GSTCD
Synonyms (NCBI Gene)
-
Chromosome 4
Chromosome location 4q24
miRNA miRNA information provided by mirtarbase database.
466
miRTarBase ID miRNA Experiments Reference
MIRT019275 hsa-miR-148b-3p Microarray 17612493
MIRT021741 hsa-miR-132-3p Microarray 17612493
MIRT683600 hsa-miR-6808-5p HITS-CLIP 23313552
MIRT683599 hsa-miR-6893-5p HITS-CLIP 23313552
MIRT683598 hsa-miR-940 HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 23455924
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 24058608
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615912 25806 ENSG00000138780
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8NEC7
Protein name Glutathione S-transferase C-terminal domain-containing protein
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13679 Methyltransf_32 423 547 Methyltransferase domain Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed in cell types relevant to airway function, including airway smooth muscle cells and epithelial cells. {ECO:0000269|PubMed:24058608}.
Sequence
MKAIKKSLTEEEYLYLDFSHQTEGCIFPLHTSVTLFLLSYCDCKIFKICLVVTKEVSRDS
SLLRDDLIQDVEIQIISRQELPPIVQNCCLPAVVERSDNFCRAGLAVVLRHIIQKSYEAD
PLKKELLELLGFKKTCLKACAEVSQWTRLCELTIPLAIENFLRESSDQPPTIPVEILQLE
KKLSEPVRVHNDDKLRRQKLKQQKADGVGPPLTKGKAKSKVHTQETSEGLDSSSKSLELK
VAFSKLTVQEEPATTNREPSHIRKAKASDLPPLEHVFAEGLYFTLADIVLLPCIHHFLVI
ISRKFSEKLVEFPLLASWYQRIQEVPGVKTAASKCGIQFLHLPKLLTTSTEQHPNLCEVP
GVEEQSDPLFIGGPRPTMAKLMEKGIEVMFSPHPCPTWTLDWNVLPAAVSPKEGKMSSDR
ALRKQQQLNNLVYVVTNQAKPGDRIVDFCSGGGHVGIVLAHMLPSCQVTLIENKELSLIR
AKKRSDELGLSNIWFIQANMEYFTGMFNIGVALHACGVATDMVIEHCIKTRASFVTCPCC
YGFIQNT
SKFNFPKSEQFKKTLSYKEHMILCRFADQTAVQLPPQRRLIGKQCMCLVDLDR
ARAAEECGYSVQVISMEPESCSPKNNMIVGVPI
Sequence length 633
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
6
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CHRONIC OBSTRUCTIVE PULMONARY DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DEMENTIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PROSTATIC NEOPLASMS CTD
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Chronic Obstructive Airway Disease Chronic Obstructive Pulmonary Disease BEFREE 21965014
★☆☆☆☆
Found in Text Mining only
Chronic Obstructive Airway Disease Chronic Obstructive Pulmonary Disease GWASCAT_DG 28166215
★☆☆☆☆
Found in Text Mining only
Hypertensive disease Hypertension BEFREE 24915237
★☆☆☆☆
Found in Text Mining only
Lung Diseases Lung disease Pubtator 20010835 Associate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of prostate Prostate cancer CTD_human_DG 21716162
★☆☆☆☆
Found in Text Mining only
Prostatic Neoplasms Prostatic Neoplasms CTD_human_DG 21716162
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Pulmonary Disease Chronic Obstructive Chronic obstructive pulmonary disease Pubtator 21659657, 21965014 Associate
★☆☆☆☆
Found in Text Mining only
Respiratory Tract Diseases Respiratory system infectious disease Pubtator 20010834 Associate
★☆☆☆☆
Found in Text Mining only