Gene Gene information from NCBI Gene database.
Entrez ID 79745
Gene name CAP-Gly domain containing linker protein family member 4
Gene symbol CLIP4
Synonyms (NCBI Gene)
RSNL2
Chromosome 2
Chromosome location 2p23.2
miRNA miRNA information provided by mirtarbase database.
368
miRTarBase ID miRNA Experiments Reference
MIRT024364 hsa-miR-215-5p Microarray 19074876
MIRT026491 hsa-miR-192-5p Microarray 19074876
MIRT030805 hsa-miR-21-5p Microarray 18591254
MIRT054113 hsa-miR-21-3p Microarray 22995316
MIRT302422 hsa-miR-548c-3p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183, 32353859, 33060197, 36217030
GO:0005634 Component Nucleus IBA
GO:0005938 Component Cell cortex IBA
GO:0031122 Process Cytoplasmic microtubule organization IBA
GO:0035371 Component Microtubule plus-end IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N3C7
Protein name CAP-Gly domain-containing linker protein 4 (Restin-like protein 2)
PDB 2Z0W
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12796 Ank_2 125 217 Ankyrin repeats (3 copies) Repeat
PF01302 CAP_GLY 285 349 CAP-Gly domain Domain
PF01302 CAP_GLY 487 551 CAP-Gly domain Domain
PF01302 CAP_GLY 625 690 CAP-Gly domain Domain
Sequence
MTIEDLPDFPLEGNPLFGRYPFIFSASDTPVIFSISAAPMPSDCEFSFFDPNDASCQEIL
FDPKTSVSELFAILRQWVPQVQQNIDIIGNEILKRGCNVNDRDGLTDMTLLHYTCKSGAH
GIGDVETAVKFATQLIDLGADISLRSRWTNMNALHYAAYFDVPELIRVILKTSKPKDVDA
TCSDFNFGTALHIAAYNLCAGAVKCLLEQGANPAFRN
DKGQIPADVVPDPVDMPLEMADA
AATAKEIKQMLLDAVPLSCNISKAMLPNYDHVTGKAMLTSLGLKLGDRVVIAGQKVGTLR
FCGTTEFASGQWAGIELDEPEGKNNGSVGKVQYFKCAPKYGIFAPLSKI
SKAKGRRKNIT
HTPSTKAAVPLIRSQKIDVAHVTSKVNTGLMTSKKDSASESTLSLPPGEELKTVTEKDVA
LLGSVSSCSSTSSLEHRQSYPKKQNAISSNKKTMSKSPSLSSRASAGLNSSATSTANNSR
CEGELRLGERVLVVGQRLGTIRFFGTTNFAPGYWYGIELEKPHGKNDGSVGGVQYFSCSP
RYGIFAPPSRV
QRVTDSLDTLSEISSNKQNHSYPGFRRSFSTTSASSQKEINRRNAFSKS
KAALRRSWSSTPTAGGIEGSVKLHEGSQVLLTSSNEMGTVRYVGPTDFASGIWLGLELRS
AKGKNDGSVGDKRYFTCKPNHGVLVRPSRV
TYRGINGSKLVDENC
Sequence length 705
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
LUNG CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Breast Neoplasms Breast neoplasm Pubtator 39482662 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 39920578 Associate
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Renal cell carcinoma Pubtator 27283491 Associate
★☆☆☆☆
Found in Text Mining only
Clear-cell metastatic renal cell carcinoma Renal Carcinoma BEFREE 27283491
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 31727158, 32407802 Associate
★☆☆☆☆
Found in Text Mining only
Gastritis Gastritis BEFREE 28418867
★☆☆☆☆
Found in Text Mining only
Gastritis Gastritis Pubtator 28418867 Associate
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of stomach Stomach Neoplasms BEFREE 28418867, 29901187
★☆☆☆☆
Found in Text Mining only
Renal Cell Carcinoma Renal Carcinoma BEFREE 27283491
★☆☆☆☆
Found in Text Mining only
Stomach Carcinoma Stomach Carcinoma BEFREE 28418867, 29901187
★☆☆☆☆
Found in Text Mining only