Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79730
Gene name	NOP2/Sun RNA methyltransferase family member 7
Gene symbol	NSUN7
Synonyms (NCBI Gene)	-
Chromosome	4
Chromosome location	4p14

Show/Hide all (56)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022673	hsa-miR-124-3p	Microarray	18668037
MIRT530213	hsa-miR-548c-3p	PAR-CLIP	22012620
MIRT530212	hsa-miR-551b-5p	PAR-CLIP	22012620
MIRT530211	hsa-miR-3163	PAR-CLIP	22012620
MIRT530210	hsa-miR-9-5p	PAR-CLIP	22012620
MIRT530209	hsa-miR-874-5p	PAR-CLIP	22012620
MIRT530208	hsa-miR-328-3p	PAR-CLIP	22012620
MIRT530207	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT530213	hsa-miR-548c-3p	PAR-CLIP	22012620
MIRT530212	hsa-miR-551b-5p	PAR-CLIP	22012620
MIRT530211	hsa-miR-3163	PAR-CLIP	22012620
MIRT530210	hsa-miR-9-5p	PAR-CLIP	22012620
MIRT530209	hsa-miR-874-5p	PAR-CLIP	22012620
MIRT530208	hsa-miR-328-3p	PAR-CLIP	22012620
MIRT530207	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT1195545	hsa-miR-1243	CLIP-seq
MIRT1195546	hsa-miR-1321	CLIP-seq
MIRT1195547	hsa-miR-15a	CLIP-seq
MIRT1195548	hsa-miR-15b	CLIP-seq
MIRT1195549	hsa-miR-16	CLIP-seq
MIRT1195550	hsa-miR-1827	CLIP-seq
MIRT1195551	hsa-miR-195	CLIP-seq
MIRT1195552	hsa-miR-2278	CLIP-seq
MIRT1195553	hsa-miR-2682	CLIP-seq
MIRT1195554	hsa-miR-3179	CLIP-seq
MIRT1195555	hsa-miR-3183	CLIP-seq
MIRT1195556	hsa-miR-328	CLIP-seq
MIRT1195557	hsa-miR-34a	CLIP-seq
MIRT1195558	hsa-miR-34c-5p	CLIP-seq
MIRT1195559	hsa-miR-3612	CLIP-seq
MIRT1195560	hsa-miR-370	CLIP-seq
MIRT1195561	hsa-miR-3921	CLIP-seq
MIRT1195562	hsa-miR-424	CLIP-seq
MIRT1195563	hsa-miR-4330	CLIP-seq
MIRT1195564	hsa-miR-449a	CLIP-seq
MIRT1195565	hsa-miR-449b	CLIP-seq
MIRT1195566	hsa-miR-449c	CLIP-seq
MIRT1195567	hsa-miR-4519	CLIP-seq
MIRT1195568	hsa-miR-4653-5p	CLIP-seq
MIRT1195569	hsa-miR-4723-3p	CLIP-seq
MIRT1195570	hsa-miR-4739	CLIP-seq
MIRT1195571	hsa-miR-4756-5p	CLIP-seq
MIRT1195572	hsa-miR-497	CLIP-seq
MIRT1195573	hsa-miR-509-3p	CLIP-seq
MIRT1195574	hsa-miR-593	CLIP-seq
MIRT1195575	hsa-miR-647	CLIP-seq
MIRT1195576	hsa-miR-650	CLIP-seq
MIRT1195577	hsa-miR-9	CLIP-seq
MIRT1195556	hsa-miR-328	CLIP-seq
MIRT1195577	hsa-miR-9	CLIP-seq
MIRT2285182	hsa-miR-4732-5p	CLIP-seq
MIRT2285183	hsa-miR-581	CLIP-seq
MIRT2285182	hsa-miR-4732-5p	CLIP-seq
MIRT2285183	hsa-miR-581	CLIP-seq
MIRT2285182	hsa-miR-4732-5p	CLIP-seq
MIRT2285183	hsa-miR-581	CLIP-seq

Show/Hide all (6)

GO ID	Ontology	Definition	Evidence
GO:0001510	Process	RNA methylation	IEA
GO:0003723	Function	RNA binding	IEA
GO:0006396	Process	RNA processing	IEA
GO:0008168	Function	Methyltransferase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032259	Process	Methylation	IEA

MIM	HGNC	e!Ensembl
617185	25857	ENSG00000179299

Q8NE18

Protein name

Putative methyltransferase NSUN7 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 7)

Protein function

May have S-adenosyl-L-methionine-dependent methyl-transferase activity.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01189	Methyltr_RsmB-F	293 → 461	16S rRNA methyltransferase RsmB/F	Family

Sequence

MLNSTGELEFSNEEDPEIISQLTSLPLSGGKSSAGVPEKTGYPDSVYVMAANIFQGIRIE
KSAQKVLIKYGNEPLRSLSESEDQSFQRLSYELAFSALKYQDILETILIDSCIFPSTTIP
DHLSSLIIVMLYDFQDRKFQTRVLSDNEEPISEVQEVENLLNSFKIKLAAALARCRIKHD
ALSIYHILPETVRKQELRASTLPLYAWINTCKISPEEVYNNLKRRGYNKVKSVLHIDDKV
FAVDQHCYDVLIFPSHLKNDLINIDLFKDYKLIFQDKSRSLAVHSVKALLNMDDDVLMVN
TGSWYTVSHMSILTNNNTSKVFVCGVQSQAKDPDLKTLFTKIGCKNIEILHEKFINIESK
DHRLQKVKVILLLPRCSGLGVSNPVEFILNEHEDTEFLKDHSQGGISVDKLHVLAQQQYE
QLTHAMKFTKAQAVVYCTCSVFPEENEAVVKKALEFQDLGNKGQPYRLSPPVLPLCSLKE
IQLSTDKFFRMEPSEITNGCFLSILTRERDPSETVSVNDVLARAAAKGLLDGIELGKSSK
REKKKKKSKTSLTKGATTDNGIQMKIAEFLNRETKASANLSETVTKPPLPQKNTAQVGAS
SQTRKPNKLAPHPAVPAFVKNTCPSRPRERQTHFLRPRPEDRMVALKPIKIVLPPVFMPF
SSPQGIRSRMPTQHLYCRWVAPKALVPTCLPTHSLSRKEEKPKDDTPSSLLRPPRRWL

Sequence length

718

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
INFERTILITY, MALE	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALE INFERTILITY	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PSORIASIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (8)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Alzheimer Disease	Alzheimer disease	Pubtator	36646969	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthenozoospermia	Asthenozoospermia	BEFREE	24384068, 26345859		★★★★★ ★☆☆☆☆ Found in Text Mining only
Brain Injuries Traumatic	Brain injuries	Pubtator	36646969	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	37173708	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Infertility	Infertility	Pubtator	26345859	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Infertility Male	Male infertility	Pubtator	25702163	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Failure	Liver failure	Pubtator	37173708	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Liver Neoplasms	Liver neoplasm	Pubtator	37173708	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

NSUN7 (NOP2/Sun RNA methyltransferase family member 7)