Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	79726
Gene name	WD repeat domain 59
Gene symbol	WDR59
Synonyms (NCBI Gene)	CDW12FP977p90-120
Chromosome	16
Chromosome location	16q23.1

361

Show/Hide all (361)

miRTarBase ID	miRNA	Experiments	Reference
MIRT017154	hsa-miR-335-5p	Microarray	18185580
MIRT050742	hsa-miR-17-3p	CLASH	23622248
MIRT696153	hsa-miR-590-3p	HITS-CLIP	23313552
MIRT696152	hsa-miR-6872-3p	HITS-CLIP	23313552
MIRT696151	hsa-miR-4258	HITS-CLIP	23313552
MIRT696150	hsa-miR-4735-5p	HITS-CLIP	23313552
MIRT696149	hsa-miR-138-2-3p	HITS-CLIP	23313552
MIRT696148	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT696147	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT696146	hsa-miR-4775	HITS-CLIP	23313552
MIRT696145	hsa-miR-7159-3p	HITS-CLIP	23313552
MIRT696144	hsa-miR-4482-3p	HITS-CLIP	23313552
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611985	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT611984	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT611983	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT696153	hsa-miR-590-3p	HITS-CLIP	23313552
MIRT696152	hsa-miR-6872-3p	HITS-CLIP	23313552
MIRT696151	hsa-miR-4258	HITS-CLIP	23313552
MIRT696150	hsa-miR-4735-5p	HITS-CLIP	23313552
MIRT696149	hsa-miR-138-2-3p	HITS-CLIP	23313552
MIRT696148	hsa-miR-4707-3p	HITS-CLIP	23313552
MIRT696147	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT696146	hsa-miR-4775	HITS-CLIP	23313552
MIRT696145	hsa-miR-7159-3p	HITS-CLIP	23313552
MIRT696144	hsa-miR-4482-3p	HITS-CLIP	23313552
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT615999	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT615998	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT615997	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611989	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT611988	hsa-miR-3671	HITS-CLIP	23824327
MIRT611987	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT611986	hsa-miR-607	HITS-CLIP	23824327
MIRT611985	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT611984	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT611983	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT611982	hsa-miR-1305	HITS-CLIP	23824327
MIRT611981	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT1491097	hsa-miR-1207-3p	CLIP-seq
MIRT1491098	hsa-miR-128	CLIP-seq
MIRT1491099	hsa-miR-1299	CLIP-seq
MIRT1491100	hsa-miR-136	CLIP-seq
MIRT1491101	hsa-miR-148a	CLIP-seq
MIRT1491102	hsa-miR-148b	CLIP-seq
MIRT1491103	hsa-miR-152	CLIP-seq
MIRT1491104	hsa-miR-15a	CLIP-seq
MIRT1491105	hsa-miR-15b	CLIP-seq
MIRT1491106	hsa-miR-16	CLIP-seq
MIRT1491107	hsa-miR-195	CLIP-seq
MIRT1491108	hsa-miR-28-3p	CLIP-seq
MIRT1491109	hsa-miR-3130-3p	CLIP-seq
MIRT1491110	hsa-miR-3135b	CLIP-seq
MIRT1491111	hsa-miR-3140-3p	CLIP-seq
MIRT1491112	hsa-miR-3150b-3p	CLIP-seq
MIRT1491113	hsa-miR-3182	CLIP-seq
MIRT1491114	hsa-miR-331-3p	CLIP-seq
MIRT1491115	hsa-miR-345	CLIP-seq
MIRT1491116	hsa-miR-3660	CLIP-seq
MIRT1491117	hsa-miR-3663-5p	CLIP-seq
MIRT1491118	hsa-miR-3685	CLIP-seq
MIRT1491119	hsa-miR-377	CLIP-seq
MIRT1491120	hsa-miR-3909	CLIP-seq
MIRT1491121	hsa-miR-3913-3p	CLIP-seq
MIRT1491122	hsa-miR-412	CLIP-seq
MIRT1491123	hsa-miR-424	CLIP-seq
MIRT1491124	hsa-miR-448	CLIP-seq
MIRT1491125	hsa-miR-4522	CLIP-seq
MIRT1491126	hsa-miR-4524	CLIP-seq
MIRT1491127	hsa-miR-4526	CLIP-seq
MIRT1491128	hsa-miR-4662a-5p	CLIP-seq
MIRT1491129	hsa-miR-4699-3p	CLIP-seq
MIRT1491130	hsa-miR-4726-3p	CLIP-seq
MIRT1491131	hsa-miR-4732-3p	CLIP-seq
MIRT1491132	hsa-miR-4733-3p	CLIP-seq
MIRT1491133	hsa-miR-4782-5p	CLIP-seq
MIRT1491134	hsa-miR-4784	CLIP-seq
MIRT1491135	hsa-miR-4793-3p	CLIP-seq
MIRT1491136	hsa-miR-489	CLIP-seq
MIRT1491137	hsa-miR-497	CLIP-seq
MIRT1491138	hsa-miR-500a	CLIP-seq
MIRT1491139	hsa-miR-503	CLIP-seq
MIRT1491140	hsa-miR-515-5p	CLIP-seq
MIRT1491141	hsa-miR-516b	CLIP-seq
MIRT1491142	hsa-miR-539	CLIP-seq
MIRT1491143	hsa-miR-570	CLIP-seq
MIRT1491144	hsa-miR-593	CLIP-seq
MIRT1491145	hsa-miR-646	CLIP-seq
MIRT1491146	hsa-miR-764	CLIP-seq
MIRT1491147	hsa-miR-765	CLIP-seq
MIRT2148019	hsa-miR-1324	CLIP-seq
MIRT2148020	hsa-miR-141	CLIP-seq
MIRT1491101	hsa-miR-148a	CLIP-seq
MIRT1491102	hsa-miR-148b	CLIP-seq
MIRT1491103	hsa-miR-152	CLIP-seq
MIRT2148021	hsa-miR-194	CLIP-seq
MIRT2148022	hsa-miR-200a	CLIP-seq
MIRT2148023	hsa-miR-299-5p	CLIP-seq
MIRT2148024	hsa-miR-3115	CLIP-seq
MIRT1491109	hsa-miR-3130-3p	CLIP-seq
MIRT2148025	hsa-miR-3167	CLIP-seq
MIRT2148026	hsa-miR-3192	CLIP-seq
MIRT2148027	hsa-miR-326	CLIP-seq
MIRT2148028	hsa-miR-330-5p	CLIP-seq
MIRT2148029	hsa-miR-335	CLIP-seq
MIRT1491115	hsa-miR-345	CLIP-seq
MIRT2148030	hsa-miR-3591-3p	CLIP-seq
MIRT1491117	hsa-miR-3663-5p	CLIP-seq
MIRT2148031	hsa-miR-3714	CLIP-seq
MIRT2148032	hsa-miR-376c	CLIP-seq
MIRT1491120	hsa-miR-3909	CLIP-seq
MIRT2148033	hsa-miR-3925-5p	CLIP-seq
MIRT2148034	hsa-miR-3926	CLIP-seq
MIRT2148035	hsa-miR-3942-3p	CLIP-seq
MIRT2148036	hsa-miR-423-3p	CLIP-seq
MIRT2148037	hsa-miR-4314	CLIP-seq
MIRT2148038	hsa-miR-4477b	CLIP-seq
MIRT1491124	hsa-miR-448	CLIP-seq
MIRT1491125	hsa-miR-4522	CLIP-seq
MIRT2148039	hsa-miR-4642	CLIP-seq
MIRT2148040	hsa-miR-4646-5p	CLIP-seq
MIRT1491129	hsa-miR-4699-3p	CLIP-seq
MIRT2148041	hsa-miR-4720-5p	CLIP-seq
MIRT1491130	hsa-miR-4726-3p	CLIP-seq
MIRT1491132	hsa-miR-4733-3p	CLIP-seq
MIRT1491135	hsa-miR-4793-3p	CLIP-seq
MIRT2148042	hsa-miR-4799-3p	CLIP-seq
MIRT2148043	hsa-miR-5095	CLIP-seq
MIRT2148044	hsa-miR-548s	CLIP-seq
MIRT1491144	hsa-miR-593	CLIP-seq
MIRT2148045	hsa-miR-600	CLIP-seq
MIRT2148046	hsa-miR-876-3p	CLIP-seq
MIRT2148047	hsa-miR-876-5p	CLIP-seq
MIRT2368491	hsa-miR-1279	CLIP-seq
MIRT1491100	hsa-miR-136	CLIP-seq
MIRT2148020	hsa-miR-141	CLIP-seq
MIRT1491101	hsa-miR-148a	CLIP-seq
MIRT1491102	hsa-miR-148b	CLIP-seq
MIRT1491103	hsa-miR-152	CLIP-seq
MIRT2368492	hsa-miR-193a-3p	CLIP-seq
MIRT2368493	hsa-miR-193b	CLIP-seq
MIRT2148021	hsa-miR-194	CLIP-seq
MIRT2148022	hsa-miR-200a	CLIP-seq
MIRT1491109	hsa-miR-3130-3p	CLIP-seq
MIRT2148030	hsa-miR-3591-3p	CLIP-seq
MIRT1491117	hsa-miR-3663-5p	CLIP-seq
MIRT2148032	hsa-miR-376c	CLIP-seq
MIRT2148038	hsa-miR-4477b	CLIP-seq
MIRT1491124	hsa-miR-448	CLIP-seq
MIRT2368494	hsa-miR-4509	CLIP-seq
MIRT1491125	hsa-miR-4522	CLIP-seq
MIRT2148039	hsa-miR-4642	CLIP-seq
MIRT1491129	hsa-miR-4699-3p	CLIP-seq
MIRT2148041	hsa-miR-4720-5p	CLIP-seq
MIRT2368495	hsa-miR-4744	CLIP-seq
MIRT1491135	hsa-miR-4793-3p	CLIP-seq
MIRT2368496	hsa-miR-4797-3p	CLIP-seq
MIRT2148042	hsa-miR-4799-3p	CLIP-seq
MIRT2368497	hsa-miR-4799-5p	CLIP-seq
MIRT1491138	hsa-miR-500a	CLIP-seq
MIRT2148043	hsa-miR-5095	CLIP-seq
MIRT1491143	hsa-miR-570	CLIP-seq
MIRT1491144	hsa-miR-593	CLIP-seq
MIRT2368498	hsa-miR-595	CLIP-seq
MIRT2148045	hsa-miR-600	CLIP-seq
MIRT2368499	hsa-miR-634	CLIP-seq
MIRT2148032	hsa-miR-376c	CLIP-seq
MIRT2662093	hsa-miR-1275	CLIP-seq
MIRT2662094	hsa-miR-1291	CLIP-seq
MIRT1491100	hsa-miR-136	CLIP-seq
MIRT2148020	hsa-miR-141	CLIP-seq
MIRT2662095	hsa-miR-1910	CLIP-seq
MIRT2368492	hsa-miR-193a-3p	CLIP-seq
MIRT2368493	hsa-miR-193b	CLIP-seq
MIRT2148021	hsa-miR-194	CLIP-seq
MIRT2148022	hsa-miR-200a	CLIP-seq
MIRT2662096	hsa-miR-2467-3p	CLIP-seq
MIRT2148024	hsa-miR-3115	CLIP-seq
MIRT1491111	hsa-miR-3140-3p	CLIP-seq
MIRT2662097	hsa-miR-3144-5p	CLIP-seq
MIRT2662098	hsa-miR-3160-3p	CLIP-seq
MIRT2662099	hsa-miR-3189-3p	CLIP-seq
MIRT2662100	hsa-miR-3191	CLIP-seq
MIRT2148026	hsa-miR-3192	CLIP-seq
MIRT2148027	hsa-miR-326	CLIP-seq
MIRT2662101	hsa-miR-328	CLIP-seq
MIRT2148028	hsa-miR-330-5p	CLIP-seq
MIRT2148029	hsa-miR-335	CLIP-seq
MIRT2148030	hsa-miR-3591-3p	CLIP-seq
MIRT2148031	hsa-miR-3714	CLIP-seq
MIRT2148032	hsa-miR-376c	CLIP-seq
MIRT1491120	hsa-miR-3909	CLIP-seq
MIRT2148034	hsa-miR-3926	CLIP-seq
MIRT2662102	hsa-miR-4254	CLIP-seq
MIRT2662103	hsa-miR-4308	CLIP-seq
MIRT2148037	hsa-miR-4314	CLIP-seq
MIRT2662104	hsa-miR-4525	CLIP-seq
MIRT2148040	hsa-miR-4646-5p	CLIP-seq
MIRT2662105	hsa-miR-4652-5p	CLIP-seq
MIRT2662106	hsa-miR-4665-5p	CLIP-seq
MIRT2662107	hsa-miR-4667-5p	CLIP-seq
MIRT2662108	hsa-miR-4700-5p	CLIP-seq
MIRT2662109	hsa-miR-4723-5p	CLIP-seq
MIRT1491130	hsa-miR-4726-3p	CLIP-seq
MIRT1491132	hsa-miR-4733-3p	CLIP-seq
MIRT2662110	hsa-miR-4793-5p	CLIP-seq
MIRT2148043	hsa-miR-5095	CLIP-seq
MIRT1491140	hsa-miR-515-5p	CLIP-seq
MIRT2148044	hsa-miR-548s	CLIP-seq
MIRT1491143	hsa-miR-570	CLIP-seq
MIRT2148045	hsa-miR-600	CLIP-seq
MIRT2662111	hsa-miR-625	CLIP-seq
MIRT1491146	hsa-miR-764	CLIP-seq
MIRT2662093	hsa-miR-1275	CLIP-seq
MIRT2662094	hsa-miR-1291	CLIP-seq
MIRT1491100	hsa-miR-136	CLIP-seq
MIRT2148020	hsa-miR-141	CLIP-seq
MIRT2662095	hsa-miR-1910	CLIP-seq
MIRT2368492	hsa-miR-193a-3p	CLIP-seq
MIRT2368493	hsa-miR-193b	CLIP-seq
MIRT2148021	hsa-miR-194	CLIP-seq
MIRT2148022	hsa-miR-200a	CLIP-seq
MIRT2662096	hsa-miR-2467-3p	CLIP-seq
MIRT1491111	hsa-miR-3140-3p	CLIP-seq
MIRT2662097	hsa-miR-3144-5p	CLIP-seq
MIRT2662098	hsa-miR-3160-3p	CLIP-seq
MIRT2662099	hsa-miR-3189-3p	CLIP-seq
MIRT2662100	hsa-miR-3191	CLIP-seq
MIRT2662101	hsa-miR-328	CLIP-seq
MIRT2148029	hsa-miR-335	CLIP-seq
MIRT2148030	hsa-miR-3591-3p	CLIP-seq
MIRT2148031	hsa-miR-3714	CLIP-seq
MIRT2148034	hsa-miR-3926	CLIP-seq
MIRT2662102	hsa-miR-4254	CLIP-seq
MIRT2662103	hsa-miR-4308	CLIP-seq
MIRT2662104	hsa-miR-4525	CLIP-seq
MIRT2662105	hsa-miR-4652-5p	CLIP-seq
MIRT2662106	hsa-miR-4665-5p	CLIP-seq
MIRT2662107	hsa-miR-4667-5p	CLIP-seq
MIRT2662108	hsa-miR-4700-5p	CLIP-seq
MIRT2662109	hsa-miR-4723-5p	CLIP-seq
MIRT1491132	hsa-miR-4733-3p	CLIP-seq
MIRT2662110	hsa-miR-4793-5p	CLIP-seq
MIRT2148043	hsa-miR-5095	CLIP-seq
MIRT1491140	hsa-miR-515-5p	CLIP-seq
MIRT2148044	hsa-miR-548s	CLIP-seq
MIRT1491143	hsa-miR-570	CLIP-seq
MIRT2148045	hsa-miR-600	CLIP-seq
MIRT2662111	hsa-miR-625	CLIP-seq
MIRT1491146	hsa-miR-764	CLIP-seq

Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25263562, 26972053, 28199315, 28514442, 33961781, 36931259
GO:0005764	Component	Lysosome	IEA
GO:0005765	Component	Lysosomal membrane	IDA	28199306
GO:0005765	Component	Lysosomal membrane	IEA
GO:0005765	Component	Lysosomal membrane	TAS
GO:0005774	Component	Vacuolar membrane	IBA
GO:0005829	Component	Cytosol	IDA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0031669	Process	Cellular response to nutrient levels	IDA	35831510, 36528027
GO:0034198	Process	Cellular response to amino acid starvation	IBA
GO:0034198	Process	Cellular response to amino acid starvation	IMP	23723238
GO:0035591	Function	Signaling adaptor activity	IBA
GO:0035859	Component	Seh1-associated complex	IBA
GO:0035859	Component	Seh1-associated complex	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061700	Component	GATOR2 complex	IDA	35831510, 36528027
GO:0061700	Component	GATOR2 complex	NAS	23723238
GO:1904262	Process	Negative regulation of TORC1 signaling	NAS	23723238
GO:1904263	Process	Positive regulation of TORC1 signaling	IBA
GO:1904263	Process	Positive regulation of TORC1 signaling	IDA	35831510, 36528027
GO:1904263	Process	Positive regulation of TORC1 signaling	NAS	23723238

MIM	HGNC	e!Ensembl
617418	25706	ENSG00000103091

Q6PJI9

Protein name

GATOR2 complex protein WDR59 (WD repeat-containing protein 59)

Protein function

As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway (PubMed:23723238, PubMed:25457612, PubMed:27487210, PubMed:35831510, PubMed:36528027, PubMed:36577058). The GATOR2 c

PDB

7UHY

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00400	WD40	95 → 134	WD domain, G-beta repeat	Repeat
PF00400	WD40	182 → 220	WD domain, G-beta repeat	Repeat
PF17120	Zn_ribbon_17	918 → 973		Domain

Sequence

MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKW
DIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDL
LVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKP
STAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRKYLNILPCQVPVWKA
RYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDY
QLVTWSRDQTLRMWRVDSQMQRLCANDILDGVDEFIESISLLPEPEKTLHTEDTDHQHTA
SHGEEEALKEDPPRNLLEERKSDQLGLPQTLQQEFSLINVQIRNVNVEMDAADRSCTVSV
HCSNHRVKMLVKFPAQYPNNAAPSFQFINPTTITSTMKAKLLKILKDTALQKVKRGQSCL
EPCLRQLVSCLESFVNQEDSASSNPFALPNSVTPPLPTFARVTTAYGSYQDANIPFPRTS
GARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLY
SGSPTRSEKEQVSISSFYYKERKSRRWKSKREGSDSGNRQIKAAGKVIIQDIACLLPVHK
SLGELYILNVNDIQETCQKNAASALLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWA
RHPFGRQLLESLLAHYCRLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHS
RYPSFTSSGSCSSMSDPGLNTGGWNIAGREAEHLSSPWGESSPEELRFGSLTYSDPRERE
RDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPDPHKGIEFGV
YCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVC
PTGCGCHCLLESTF

Sequence length

974

Interactions

View interactions

	KEGG		Reactome
	mTOR signaling pathway		Amino acids regulate mTORC1

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
DEMENTIA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
LEPROSY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PELVIC ORGAN PROLAPSE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UPPER AERODIGESTIVE TRACT NEOPLASM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (3)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Epilepsies, Partial	Epilepsy	BEFREE	27173016		★★★★★ ★☆☆☆☆ Found in Text Mining only
Focal cortical dysplasia	Focal cortical dysplasia	BEFREE	27173016		★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Pancreatic neoplasm	Pubtator	31917448	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only

WDR59 (WD repeat domain 59)