VPS37B (VPS37B subunit of ESCRT-I)

Gene

• Entrez ID: 79720
• Gene name: VPS37B subunit of ESCRT-I
• Gene symbol: VPS37B
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12q24.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019654	hsa-miR-378a-3p	Sequencing	20371350
MIRT025496	hsa-miR-34a-5p	Sequencing	20371350
MIRT043537	hsa-miR-331-3p	CLASH	23622248
MIRT039479	hsa-miR-652-3p	CLASH	23622248
MIRT036597	hsa-miR-940	CLASH	23622248
MIRT052888	hsa-miR-3928-3p	CLASH	23622248
MIRT513626	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT513625	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT513624	hsa-miR-130a-3p	PAR-CLIP	23446348
MIRT513623	hsa-miR-130b-3p	PAR-CLIP	23446348
MIRT513622	hsa-miR-301a-3p	PAR-CLIP	23446348
MIRT513621	hsa-miR-301b-3p	PAR-CLIP	23446348
MIRT513620	hsa-miR-3666	PAR-CLIP	23446348
MIRT513619	hsa-miR-4295	PAR-CLIP	23446348
MIRT513618	hsa-miR-454-3p	PAR-CLIP	23446348
MIRT513617	hsa-miR-148a-3p	PAR-CLIP	23446348
MIRT513616	hsa-miR-148b-3p	PAR-CLIP	23446348
MIRT513615	hsa-miR-152-3p	PAR-CLIP	23446348
MIRT513614	hsa-miR-194-3p	PAR-CLIP	23446348
MIRT513613	hsa-miR-1825	PAR-CLIP	23446348
MIRT513612	hsa-miR-518c-5p	PAR-CLIP	23446348
MIRT513611	hsa-miR-4638-3p	PAR-CLIP	23446348
MIRT019654	hsa-miR-378a-3p	PAR-CLIP	23446348
MIRT513610	hsa-miR-378b	PAR-CLIP	23446348
MIRT513609	hsa-miR-378c	PAR-CLIP	23446348
MIRT513608	hsa-miR-378d	PAR-CLIP	23446348
MIRT513607	hsa-miR-378e	PAR-CLIP	23446348
MIRT513606	hsa-miR-378f	PAR-CLIP	23446348
MIRT513604	hsa-miR-378h	PAR-CLIP	23446348
MIRT513605	hsa-miR-378i	PAR-CLIP	23446348
MIRT513603	hsa-miR-422a	PAR-CLIP	23446348
MIRT025496	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT513602	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT513601	hsa-miR-449a	PAR-CLIP	23446348
MIRT513600	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT513599	hsa-miR-296-5p	PAR-CLIP	23446348
MIRT112704	hsa-miR-6724-5p	PAR-CLIP	23446348
MIRT112705	hsa-miR-6773-5p	PAR-CLIP	23446348
MIRT460792	hsa-miR-28-5p	PAR-CLIP	23592263
MIRT460791	hsa-miR-3139	PAR-CLIP	23592263
MIRT460790	hsa-miR-708-5p	PAR-CLIP	23592263
MIRT460788	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT460789	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT036597	hsa-miR-940	PAR-CLIP	23592263
MIRT460787	hsa-miR-4514	PAR-CLIP	23592263
MIRT460786	hsa-miR-4692	PAR-CLIP	23592263
MIRT460785	hsa-miR-3937	PAR-CLIP	23592263
MIRT460784	hsa-miR-4645-5p	PAR-CLIP	23592263
MIRT460783	hsa-miR-4673	PAR-CLIP	23592263
MIRT460782	hsa-miR-6746-5p	PAR-CLIP	23592263
MIRT460781	hsa-miR-4487	PAR-CLIP	23592263
MIRT460780	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT460779	hsa-miR-765	PAR-CLIP	23592263
MIRT460778	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT460777	hsa-miR-8085	PAR-CLIP	23592263
MIRT513625	hsa-miR-19a-3p	HITS-CLIP	22473208
MIRT513626	hsa-miR-19b-3p	HITS-CLIP	22473208
MIRT513626	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT513625	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT513624	hsa-miR-130a-3p	PAR-CLIP	23446348
MIRT513623	hsa-miR-130b-3p	PAR-CLIP	23446348
MIRT513622	hsa-miR-301a-3p	PAR-CLIP	23446348
MIRT513621	hsa-miR-301b-3p	PAR-CLIP	23446348
MIRT513620	hsa-miR-3666	PAR-CLIP	23446348
MIRT513619	hsa-miR-4295	PAR-CLIP	23446348
MIRT513618	hsa-miR-454-3p	PAR-CLIP	23446348
MIRT513617	hsa-miR-148a-3p	PAR-CLIP	23446348
MIRT513616	hsa-miR-148b-3p	PAR-CLIP	23446348
MIRT513615	hsa-miR-152-3p	PAR-CLIP	23446348
MIRT513614	hsa-miR-194-3p	PAR-CLIP	23446348
MIRT513613	hsa-miR-1825	PAR-CLIP	23446348
MIRT513612	hsa-miR-518c-5p	PAR-CLIP	23446348
MIRT513611	hsa-miR-4638-3p	PAR-CLIP	23446348
MIRT019654	hsa-miR-378a-3p	PAR-CLIP	23446348
MIRT513610	hsa-miR-378b	PAR-CLIP	23446348
MIRT513609	hsa-miR-378c	PAR-CLIP	23446348
MIRT513608	hsa-miR-378d	PAR-CLIP	23446348
MIRT513607	hsa-miR-378e	PAR-CLIP	23446348
MIRT513606	hsa-miR-378f	PAR-CLIP	23446348
MIRT513604	hsa-miR-378h	PAR-CLIP	23446348
MIRT513605	hsa-miR-378i	PAR-CLIP	23446348
MIRT513603	hsa-miR-422a	PAR-CLIP	23446348
MIRT025496	hsa-miR-34a-5p	PAR-CLIP	23446348
MIRT513602	hsa-miR-34c-5p	PAR-CLIP	23446348
MIRT513601	hsa-miR-449a	PAR-CLIP	23446348
MIRT513600	hsa-miR-449b-5p	PAR-CLIP	23446348
MIRT513599	hsa-miR-296-5p	PAR-CLIP	23446348
MIRT112704	hsa-miR-6724-5p	PAR-CLIP	23446348
MIRT112705	hsa-miR-6773-5p	PAR-CLIP	23446348
MIRT460792	hsa-miR-28-5p	PAR-CLIP	23592263
MIRT460791	hsa-miR-3139	PAR-CLIP	23592263
MIRT460790	hsa-miR-708-5p	PAR-CLIP	23592263
MIRT460788	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT460789	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT036597	hsa-miR-940	PAR-CLIP	23592263
MIRT460787	hsa-miR-4514	PAR-CLIP	23592263
MIRT460786	hsa-miR-4692	PAR-CLIP	23592263
MIRT460785	hsa-miR-3937	PAR-CLIP	23592263
MIRT460784	hsa-miR-4645-5p	PAR-CLIP	23592263
MIRT460783	hsa-miR-4673	PAR-CLIP	23592263
MIRT460782	hsa-miR-6746-5p	PAR-CLIP	23592263
MIRT460781	hsa-miR-4487	PAR-CLIP	23592263
MIRT460780	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT460779	hsa-miR-765	PAR-CLIP	23592263
MIRT460778	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT460777	hsa-miR-8085	PAR-CLIP	23592263
MIRT1486758	hsa-miR-4480	CLIP-seq
MIRT1486759	hsa-miR-450b-5p	CLIP-seq
MIRT1486760	hsa-miR-4659a-3p	CLIP-seq
MIRT1486761	hsa-miR-4659b-3p	CLIP-seq
MIRT1486762	hsa-miR-891b	CLIP-seq
MIRT2146385	hsa-miR-1226	CLIP-seq
MIRT2146386	hsa-miR-1275	CLIP-seq
MIRT2146387	hsa-miR-1291	CLIP-seq
MIRT2146388	hsa-miR-129-3p	CLIP-seq
MIRT2146389	hsa-miR-144	CLIP-seq
MIRT2146390	hsa-miR-19a	CLIP-seq
MIRT2146391	hsa-miR-19b	CLIP-seq
MIRT2146392	hsa-miR-3155	CLIP-seq
MIRT2146393	hsa-miR-3155b	CLIP-seq
MIRT2146394	hsa-miR-3190	CLIP-seq
MIRT2146395	hsa-miR-324-5p	CLIP-seq
MIRT2146396	hsa-miR-3656	CLIP-seq
MIRT2146397	hsa-miR-3667-3p	CLIP-seq
MIRT2146398	hsa-miR-3677-5p	CLIP-seq
MIRT2146399	hsa-miR-3919	CLIP-seq
MIRT2146400	hsa-miR-3934	CLIP-seq
MIRT2146401	hsa-miR-4304	CLIP-seq
MIRT2146402	hsa-miR-4308	CLIP-seq
MIRT2146403	hsa-miR-4436b-5p	CLIP-seq
MIRT2146404	hsa-miR-4446-3p	CLIP-seq
MIRT2146405	hsa-miR-4468	CLIP-seq
MIRT2146406	hsa-miR-4525	CLIP-seq
MIRT2146407	hsa-miR-4665-5p	CLIP-seq
MIRT2146408	hsa-miR-4685-5p	CLIP-seq
MIRT2146409	hsa-miR-4686	CLIP-seq
MIRT2146410	hsa-miR-4723-5p	CLIP-seq
MIRT2146411	hsa-miR-4733-3p	CLIP-seq
MIRT2146412	hsa-miR-4756-3p	CLIP-seq
MIRT2146413	hsa-miR-484	CLIP-seq
MIRT2146414	hsa-miR-552	CLIP-seq
MIRT2146415	hsa-miR-625	CLIP-seq
MIRT2146416	hsa-miR-661	CLIP-seq
MIRT2146417	hsa-miR-766	CLIP-seq
MIRT2146418	hsa-miR-767-3p	CLIP-seq
MIRT2146419	hsa-miR-891a	CLIP-seq
MIRT2146420	hsa-miR-941	CLIP-seq
MIRT2366868	hsa-miR-1	CLIP-seq
MIRT2366869	hsa-miR-101	CLIP-seq
MIRT2366870	hsa-miR-1204	CLIP-seq
MIRT2366871	hsa-miR-1207-5p	CLIP-seq
MIRT2366872	hsa-miR-122	CLIP-seq
MIRT2366873	hsa-miR-1224-5p	CLIP-seq
MIRT2366874	hsa-miR-1233	CLIP-seq
MIRT2366875	hsa-miR-1247	CLIP-seq
MIRT2366876	hsa-miR-1271	CLIP-seq
MIRT2366877	hsa-miR-1273e	CLIP-seq
MIRT2146386	hsa-miR-1275	CLIP-seq
MIRT2146387	hsa-miR-1291	CLIP-seq
MIRT2146388	hsa-miR-129-3p	CLIP-seq
MIRT2366878	hsa-miR-1297	CLIP-seq
MIRT2366879	hsa-miR-1324	CLIP-seq
MIRT2146389	hsa-miR-144	CLIP-seq
MIRT2366880	hsa-miR-1538	CLIP-seq
MIRT2366881	hsa-miR-15a	CLIP-seq
MIRT2366882	hsa-miR-15b	CLIP-seq
MIRT2366883	hsa-miR-16	CLIP-seq
MIRT2366884	hsa-miR-188-3p	CLIP-seq
MIRT2366885	hsa-miR-1915	CLIP-seq
MIRT2366886	hsa-miR-195	CLIP-seq
MIRT2146390	hsa-miR-19a	CLIP-seq
MIRT2146391	hsa-miR-19b	CLIP-seq
MIRT2366887	hsa-miR-202	CLIP-seq
MIRT2366888	hsa-miR-206	CLIP-seq
MIRT2366889	hsa-miR-2277-3p	CLIP-seq
MIRT2366890	hsa-miR-2278	CLIP-seq
MIRT2366891	hsa-miR-2682	CLIP-seq
MIRT2366892	hsa-miR-26a	CLIP-seq
MIRT2366893	hsa-miR-26b	CLIP-seq
MIRT2366894	hsa-miR-3065-3p	CLIP-seq
MIRT2366895	hsa-miR-3127-5p	CLIP-seq
MIRT2366896	hsa-miR-3136-3p	CLIP-seq
MIRT2366897	hsa-miR-3144-5p	CLIP-seq
MIRT2146392	hsa-miR-3155	CLIP-seq
MIRT2146393	hsa-miR-3155b	CLIP-seq
MIRT2366898	hsa-miR-3156-3p	CLIP-seq
MIRT2366899	hsa-miR-3163	CLIP-seq
MIRT2366900	hsa-miR-3175	CLIP-seq
MIRT2366901	hsa-miR-3180	CLIP-seq
MIRT2366902	hsa-miR-3180-3p	CLIP-seq
MIRT2366903	hsa-miR-3185	CLIP-seq
MIRT2146394	hsa-miR-3190	CLIP-seq
MIRT2366904	hsa-miR-3191	CLIP-seq
MIRT2366905	hsa-miR-3196	CLIP-seq
MIRT2366906	hsa-miR-3198	CLIP-seq
MIRT2366907	hsa-miR-3199	CLIP-seq
MIRT2366908	hsa-miR-320a	CLIP-seq
MIRT2366909	hsa-miR-320b	CLIP-seq
MIRT2366910	hsa-miR-320c	CLIP-seq
MIRT2366911	hsa-miR-320d	CLIP-seq
MIRT2146395	hsa-miR-324-5p	CLIP-seq
MIRT2366912	hsa-miR-335	CLIP-seq
MIRT2366913	hsa-miR-34a	CLIP-seq
MIRT2366914	hsa-miR-3653	CLIP-seq
MIRT2366915	hsa-miR-3658	CLIP-seq
MIRT2146397	hsa-miR-3667-3p	CLIP-seq
MIRT2366916	hsa-miR-3675-5p	CLIP-seq
MIRT2146398	hsa-miR-3677-5p	CLIP-seq
MIRT2366917	hsa-miR-3688-5p	CLIP-seq
MIRT2366918	hsa-miR-3714	CLIP-seq
MIRT2366919	hsa-miR-377	CLIP-seq
MIRT2366920	hsa-miR-378	CLIP-seq
MIRT2366921	hsa-miR-3918	CLIP-seq
MIRT2146400	hsa-miR-3934	CLIP-seq
MIRT2366922	hsa-miR-3940-3p	CLIP-seq
MIRT2366923	hsa-miR-3944-5p	CLIP-seq
MIRT2366924	hsa-miR-424	CLIP-seq
MIRT2366925	hsa-miR-4271	CLIP-seq
MIRT2366926	hsa-miR-4277	CLIP-seq
MIRT2366927	hsa-miR-4285	CLIP-seq
MIRT2366928	hsa-miR-4301	CLIP-seq
MIRT2146401	hsa-miR-4304	CLIP-seq
MIRT2366929	hsa-miR-4309	CLIP-seq
MIRT2366930	hsa-miR-4420	CLIP-seq
MIRT2366931	hsa-miR-4429	CLIP-seq
MIRT2366932	hsa-miR-4447	CLIP-seq
MIRT2366933	hsa-miR-4465	CLIP-seq
MIRT2146405	hsa-miR-4468	CLIP-seq
MIRT2366934	hsa-miR-4472	CLIP-seq
MIRT2366935	hsa-miR-4474-3p	CLIP-seq
MIRT2366936	hsa-miR-449b	CLIP-seq
MIRT2366937	hsa-miR-449c	CLIP-seq
MIRT2366938	hsa-miR-4515	CLIP-seq
MIRT2366939	hsa-miR-451b	CLIP-seq
MIRT2146406	hsa-miR-4525	CLIP-seq
MIRT2366940	hsa-miR-4636	CLIP-seq
MIRT2366941	hsa-miR-4642	CLIP-seq
MIRT2366942	hsa-miR-4643	CLIP-seq
MIRT2366943	hsa-miR-4651	CLIP-seq
MIRT2366944	hsa-miR-4652-5p	CLIP-seq
MIRT2366945	hsa-miR-4662a-3p	CLIP-seq
MIRT2146407	hsa-miR-4665-5p	CLIP-seq
MIRT2366946	hsa-miR-4667-5p	CLIP-seq
MIRT2146408	hsa-miR-4685-5p	CLIP-seq
MIRT2146409	hsa-miR-4686	CLIP-seq
MIRT2366947	hsa-miR-4694-3p	CLIP-seq
MIRT2366948	hsa-miR-4699-5p	CLIP-seq
MIRT2366949	hsa-miR-4700-5p	CLIP-seq
MIRT2366950	hsa-miR-4717-3p	CLIP-seq
MIRT2146410	hsa-miR-4723-5p	CLIP-seq
MIRT2366951	hsa-miR-4725-3p	CLIP-seq
MIRT2366952	hsa-miR-4730	CLIP-seq
MIRT2366953	hsa-miR-4736	CLIP-seq
MIRT2366954	hsa-miR-4743	CLIP-seq
MIRT2366955	hsa-miR-4745-3p	CLIP-seq
MIRT2366956	hsa-miR-4751	CLIP-seq
MIRT2366957	hsa-miR-4757-5p	CLIP-seq
MIRT2366958	hsa-miR-4763-3p	CLIP-seq
MIRT2366959	hsa-miR-4772-3p	CLIP-seq
MIRT2366960	hsa-miR-4799-5p	CLIP-seq
MIRT2146413	hsa-miR-484	CLIP-seq
MIRT2366961	hsa-miR-497	CLIP-seq
MIRT2366962	hsa-miR-518a-5p	CLIP-seq
MIRT2366963	hsa-miR-522	CLIP-seq
MIRT2366964	hsa-miR-527	CLIP-seq
MIRT2366965	hsa-miR-532-3p	CLIP-seq
MIRT2366966	hsa-miR-548an	CLIP-seq
MIRT2366967	hsa-miR-548c-3p	CLIP-seq
MIRT2366968	hsa-miR-564	CLIP-seq
MIRT2366969	hsa-miR-570	CLIP-seq
MIRT2366970	hsa-miR-582-5p	CLIP-seq
MIRT2366971	hsa-miR-608	CLIP-seq
MIRT2366972	hsa-miR-613	CLIP-seq
MIRT2146415	hsa-miR-625	CLIP-seq
MIRT2366973	hsa-miR-637	CLIP-seq
MIRT2366974	hsa-miR-658	CLIP-seq
MIRT2366975	hsa-miR-663b	CLIP-seq
MIRT2366976	hsa-miR-7	CLIP-seq
MIRT2366977	hsa-miR-708	CLIP-seq
MIRT2366978	hsa-miR-760	CLIP-seq
MIRT2366979	hsa-miR-764	CLIP-seq
MIRT2146417	hsa-miR-766	CLIP-seq
MIRT2146418	hsa-miR-767-3p	CLIP-seq
MIRT2366980	hsa-miR-935	CLIP-seq
MIRT2366981	hsa-miR-936	CLIP-seq
MIRT2146420	hsa-miR-941	CLIP-seq
MIRT2366982	hsa-miR-96	CLIP-seq
MIRT2146388	hsa-miR-129-3p	CLIP-seq
MIRT2146399	hsa-miR-3919	CLIP-seq
MIRT2146412	hsa-miR-4756-3p	CLIP-seq
MIRT2146387	hsa-miR-1291	CLIP-seq
MIRT2146388	hsa-miR-129-3p	CLIP-seq
MIRT2366901	hsa-miR-3180	CLIP-seq
MIRT2366902	hsa-miR-3180-3p	CLIP-seq
MIRT2660512	hsa-miR-3184	CLIP-seq
MIRT2366905	hsa-miR-3196	CLIP-seq
MIRT2660513	hsa-miR-3620	CLIP-seq
MIRT2660514	hsa-miR-3622a-5p	CLIP-seq
MIRT2366920	hsa-miR-378	CLIP-seq
MIRT2660515	hsa-miR-423-5p	CLIP-seq
MIRT2146402	hsa-miR-4308	CLIP-seq
MIRT2660516	hsa-miR-4423-3p	CLIP-seq
MIRT2660517	hsa-miR-4467	CLIP-seq
MIRT2660518	hsa-miR-4508	CLIP-seq
MIRT2660519	hsa-miR-4728-5p	CLIP-seq
MIRT2366957	hsa-miR-4757-5p	CLIP-seq
MIRT2660520	hsa-miR-542-3p	CLIP-seq
MIRT2146388	hsa-miR-129-3p	CLIP-seq
MIRT2660513	hsa-miR-3620	CLIP-seq
MIRT2660514	hsa-miR-3622a-5p	CLIP-seq
MIRT2660516	hsa-miR-4423-3p	CLIP-seq
MIRT2660517	hsa-miR-4467	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000813	Component	ESCRT I complex	IBA
GO:0000813	Component	ESCRT I complex	IDA	18005716, 22232651, 22405001
GO:0000813	Component	ESCRT I complex	IEA
GO:0000813	Component	ESCRT I complex	IPI	18005716, 21757351, 32424346
GO:0000813	Component	ESCRT I complex	TAS	20588296
GO:0005515	Function	Protein binding	IPI	15218037, 18005716, 19129479, 21516116, 25416956, 26871637, 28514442, 31515488, 32296183, 33961781, 35271311
GO:0005737	Component	Cytoplasm	IDA	15218037
GO:0005768	Component	Endosome	IDA	17940959
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IDA	17940959
GO:0006612	Process	Protein targeting to membrane	IBA
GO:0006623	Process	Protein targeting to vacuole	IBA
GO:0010008	Component	Endosome membrane	IDA	15218037
GO:0010008	Component	Endosome membrane	NAS	32424346
GO:0010008	Component	Endosome membrane	TAS
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016236	Process	Macroautophagy	IEA
GO:0016236	Process	Macroautophagy	TAS	20588296
GO:0019076	Process	Viral release from host cell	IMP	15218037
GO:0030496	Component	Midbody	IDA	19129479
GO:0031902	Component	Late endosome membrane	IEA
GO:0036258	Process	Multivesicular body assembly	IEA
GO:0036258	Process	Multivesicular body assembly	NAS	32424346
GO:0036258	Process	Multivesicular body assembly	TAS	20588296
GO:0039702	Process	Viral budding via host ESCRT complex	IEA
GO:0039702	Process	Viral budding via host ESCRT complex	TAS	20588296
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IBA
GO:0043328	Process	Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	NAS	32424346
GO:0048306	Function	Calcium-dependent protein binding	IEA
GO:0048306	Function	Calcium-dependent protein binding	IPI	23924735
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0090148	Process	Membrane fission	NAS	32424346
GO:1903774	Process	Positive regulation of viral budding via host ESCRT complex	IMP	15218037

Other IDs

• MIM: 610037
• HGNC: 25754
• e!Ensembl: ENSG00000139722

Protein

• UniProt ID: Q9H9H4
• Protein name: Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
• Protein function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:152180
• PDB: 6VME
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07200	Mod_r	11 → 156	Modifier of rudimentary (Mod(r)) protein	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Expressed in macrophages and lymphocytes. {ECO:0000269|PubMed:15218037}.
• Sequence:

  MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEETQNVQLNKEMTLASNRSLAEGNL
  LYQPQLDTLKARLTQKYQELQVLFEAYQIKKTKLDRQSSSASLETLLALLQAEGAKIEED
  TENMAEKFLDGELPLDSFIDVYQSKRKLAHMRRVKIEKLQEMVLKGQRLPQALAPLPPRL
  PELAPTAPLPYPAPEASGPPAVAPRRIPPPPPPVPAGRLATPFTAAMSSGQAVPYPGLQC
  PPLPPRVGLPTQQGFSSQFVSPYPPPLPQRPPPRLPPHQPGFILQ

• Sequence length: 285

Pathways

KEGG:

Endocytosis

Reactome:

Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
INSOMNIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Alzheimer Disease	Alzheimer disease	Pubtator	31377428	Associate	★☆☆☆☆ Found in Text Mining only