QTMAN (queuosine-tRNA mannosyltransferase)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 79712 |
| Gene name | Queuosine-tRNA mannosyltransferase |
| Gene symbol | QTMAN |
| Synonyms (NCBI Gene) |
GTDC1Hmat-Xamat-Xa
|
| Chromosome | 2 |
| Chromosome location | 2q22.3 |
|
miRNA
miRNA information provided by mirtarbase database.
557
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q4AE62 | |||||||||||||||
| Protein name | tRNA-queuosine alpha-mannosyltransferase (QTMAN) (EC 2.4.1.110) (Glycosyltransferase-like domain-containing protein 1) (Mannosyltransferase-like protein Xa) (Mat-Xa) | |||||||||||||||
| Protein function | Glycosyltransferase that specifically catalyzes mannosylation of cytoplasmic tRNA(Asp) modified with queuosine at position 34 (queuosine(34)) (PubMed:37992713). Mannosylates the cyclopentene moiety of queuosine(34) in tRNA(Asp) to form mannosyl- | |||||||||||||||
| Family and domains |
Pfam
|
|||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Expressed at high levels in the lung, brain, spleen, testis, placenta. ovary, pancreas, spleen and peripheral blood leukocytes. Expressed at low level in the colon, small intestine, kidney, skeletal muscle and thymus. Expre | |||||||||||||||
| Sequence |
|
|||||||||||||||
| Sequence length | 458 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
|
Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
5
|
|||||||||||||||||||||||||||||||||||||||||||
|
Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
|
|||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||