CCDC121 (coiled-coil domain containing 121)

Gene

• Entrez ID: 79635
• Gene name: Coiled-coil domain containing 121
• Gene symbol: CCDC121
• Synonyms (NCBI Gene): -
• Chromosome: 2
• Chromosome location: 2p23.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022834	hsa-miR-124-3p	Microarray	18668037
MIRT024586	hsa-miR-215-5p	Microarray	19074876
MIRT026670	hsa-miR-192-5p	Microarray	19074876
MIRT647539	hsa-miR-4688	HITS-CLIP	23824327
MIRT647540	hsa-miR-6743-5p	HITS-CLIP	23824327
MIRT647538	hsa-miR-6085	HITS-CLIP	23824327
MIRT647537	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT647536	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT647535	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT647534	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT647533	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT647532	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT647531	hsa-miR-4724-3p	HITS-CLIP	23824327
MIRT647530	hsa-miR-6789-5p	HITS-CLIP	23824327
MIRT647529	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT647528	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT647527	hsa-miR-135b-3p	HITS-CLIP	23824327
MIRT647539	hsa-miR-4688	HITS-CLIP	23824327
MIRT647540	hsa-miR-6743-5p	HITS-CLIP	23824327
MIRT647538	hsa-miR-6085	HITS-CLIP	23824327
MIRT647537	hsa-miR-6813-5p	HITS-CLIP	23824327
MIRT647536	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT647535	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT647534	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT647533	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT647532	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT647531	hsa-miR-4724-3p	HITS-CLIP	23824327
MIRT647530	hsa-miR-6789-5p	HITS-CLIP	23824327
MIRT647529	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT647528	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT647527	hsa-miR-135b-3p	HITS-CLIP	23824327
MIRT867776	hsa-miR-3616-5p	CLIP-seq
MIRT867777	hsa-miR-3647-5p	CLIP-seq
MIRT867778	hsa-miR-4670-3p	CLIP-seq
MIRT867779	hsa-miR-573	CLIP-seq
MIRT867780	hsa-miR-106a	CLIP-seq
MIRT867781	hsa-miR-106b	CLIP-seq
MIRT867782	hsa-miR-17	CLIP-seq
MIRT867783	hsa-miR-20a	CLIP-seq
MIRT867784	hsa-miR-20b	CLIP-seq
MIRT867785	hsa-miR-28-3p	CLIP-seq
MIRT867786	hsa-miR-3153	CLIP-seq
MIRT867787	hsa-miR-3192	CLIP-seq
MIRT867776	hsa-miR-3616-5p	CLIP-seq
MIRT867788	hsa-miR-3647-3p	CLIP-seq
MIRT867777	hsa-miR-3647-5p	CLIP-seq
MIRT867789	hsa-miR-4261	CLIP-seq
MIRT867790	hsa-miR-4314	CLIP-seq
MIRT867791	hsa-miR-4646-5p	CLIP-seq
MIRT867792	hsa-miR-4668-5p	CLIP-seq
MIRT867778	hsa-miR-4670-3p	CLIP-seq
MIRT867793	hsa-miR-4793-5p	CLIP-seq
MIRT867794	hsa-miR-519a	CLIP-seq
MIRT867795	hsa-miR-519b-3p	CLIP-seq
MIRT867796	hsa-miR-519c-3p	CLIP-seq
MIRT867797	hsa-miR-519d	CLIP-seq
MIRT867779	hsa-miR-573	CLIP-seq
MIRT867798	hsa-miR-93	CLIP-seq
MIRT867776	hsa-miR-3616-5p	CLIP-seq
MIRT867777	hsa-miR-3647-5p	CLIP-seq
MIRT867778	hsa-miR-4670-3p	CLIP-seq
MIRT867779	hsa-miR-573	CLIP-seq
MIRT867776	hsa-miR-3616-5p	CLIP-seq
MIRT867777	hsa-miR-3647-5p	CLIP-seq
MIRT867778	hsa-miR-4670-3p	CLIP-seq
MIRT867779	hsa-miR-573	CLIP-seq
MIRT1957503	hsa-miR-183	CLIP-seq
MIRT1957504	hsa-miR-3671	CLIP-seq
MIRT867786	hsa-miR-3153	CLIP-seq
MIRT867787	hsa-miR-3192	CLIP-seq
MIRT867789	hsa-miR-4261	CLIP-seq
MIRT867790	hsa-miR-4314	CLIP-seq
MIRT867791	hsa-miR-4646-5p	CLIP-seq
MIRT867792	hsa-miR-4668-5p	CLIP-seq
MIRT867793	hsa-miR-4793-5p	CLIP-seq
MIRT2194545	hsa-miR-520d-5p	CLIP-seq
MIRT2194546	hsa-miR-524-5p	CLIP-seq
MIRT2194547	hsa-miR-619	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21516116, 25416956, 31515488, 32296183

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6ZUS5
• Protein name: Coiled-coil domain-containing protein 121
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14988	DUF4515	35 → 240	Domain of unknown function (DUF4515)	Family

• Sequence:

  MTDLNKHIKQAQTQRKQLLEESRELHREKLLVQAENRFFLEYLTNKTEEYTEQPEKVWNS
  YLQKSGEIERRRQESASRYAEQISVLKTALLQKENIQSSLKRKLQAMRDIAILKEKQEKE
  IQTLQEETKKVQAETASKTREVQAQLLQEKRLLEKQLSEPDRRLLGKRKRRELNMKAQAL
  KLAAKRFIFEYSCGINRENQQFKKELLQLIEQAQKLTATQSHLENRKQQLQQEQWYLESL
  IQARQRLQGSHNQCLNRQDVPKTTPSLPQGTKSRINPK

• Sequence length: 278

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
FAMILIAL HYPERLIPIDEMIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Stomach Neoplasms	Stomach neoplasms	Pubtator	26330360	Associate	★☆☆☆☆ Found in Text Mining only